GUERLAIN Abeille Royale Day Cream for sensitive skin

How to apply

Questions and answers

What the research says

• Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components.

  Molecules, 2023

• Applying an essence containing royal jelly extract significantly increased the stratum corneum water content of the cheeks compared to placebo in healthy Japanese adults over 4 weeks.

  Journal of Cosmetic Dermatology, 2022

• A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events.

  Lasers in Medical Science, 2025

• A prototype body cream containing bee venom, propolis, honey, beeswax, and royal jelly demonstrated stability for 90 days, high antioxidant capacity of 85.45%, lack of cytotoxicity with over 70% cell viability, and no irritation or allergic reaction in dermatological analysis, while improving skin parameters in a panel test.

  Journal of Cosmetic Dermatology, 2022

• Royal jelly protects against epidermal stress caused by UVB and menadione through the upregulation of NQO1 expression by its active compound 10-hydroxy-2-decenoic acid.

  International Journal of Molecular Sciences, 2021

• Defensin-1 from royal jelly stimulated MMP-9 secretion and increased keratinocyte migration and wound closure in vitro, and promoted re-epithelisation and wound closure in uninfected excision wounds.

  Scientific Reports, 2017

• Honey-based dressings reduced mean healing duration, length of hospital stay, and VAS pain scores compared with povidone iodine-based dressings in 1236 participants.

  Journal of Wound Care, 2021

• Topical honey application improved the mean duration of attacks and pain, occurrence of crusting, and healing time compared to acyclovir cream in 16 adult patients with recurrent labial and genital herpes lesions.

  Medical Science Monitor, 2004

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers.

  Experimental Dermatology, 2003

• Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation.

  Journal of Periodontology, 2009

• Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream.

  Journal of Cosmetic Dermatology, 2022

• A skin barrier restoring cream with shea butter, silkflo, and vitamin E increased type I procollagen synthesis, enhanced antioxidant enzyme activity, decreased reactive oxygen species generation, and promoted hyaluronic acid production in H2O2-stimulated human keratinocyte cells compared to untreated cells.

  International Journal of Cosmetic Science, 2025

Ingredients

Water, Glycerin, Propanediol, C15-19 Alkane, Isononyl Isononanoate, Honey, Jojoba Esters, Glyceryl Stearate, Peg-100 Stearate, Cellulose, Ammonium Acryloyldimethyltaurate Vp Copolymer, Cetyl Alcohol, Dimethicone, Stearyl Alcohol, Royal Jelly, Phenoxyethanol, Ascorbyl Glucoside, Caprylyl Glycol, Steareth-21, Parfum, Butyrospermum Parkii Butter Shea Butter, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Avena Sativa Kernel Extract Oat Kernel Extract, Tocopheryl Acetate, Xanthan Gum, Sodium Hydroxide, Tetrasodium Edta, Glyceryl Polymethacrylate, Centella Asiatica Leaf Extract, Sodium Hyaluronate, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Peg-8, Tocopherol, Sodium Benzoate, Butylene Glycol, Sodium Lactate, Palmitoyl Hexapeptide-12, Zingiber Officinale Root Extract, Bht, Citric Acid

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.