# Eucerin Hyaluron-Filler Epigenetic Serum for sensitive skin

**Lovi Fit: Average fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/au/p/eucerin/hyaluron-filler-epigenetic-serum/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Australia.

Brand: [Eucerin](https://lovi.care/skincare/au/brands/eucerin)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/au/best/moisturizers)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for sensitive skin; other moisturizers fit it better.

## Why this fit

- Suitable for normal skin, this serum offers moderate moisturizing due to glycerin and hyaluronic acid, which provide hydration that can support your redness and irritation.
- Panthenol further aids in barrier repair, offering general skincare benefits that align with your needs.
- The formula is safe for your sensitive skin, as it lacks prohibited or harsh ingredients that could cause irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/au/p/eucerin/hyaluron-filler-epigenetic-serum/for/oily-skin): Low
- [Dry skin](https://lovi.care/skincare/au/p/eucerin/hyaluron-filler-epigenetic-serum/for/dry-skin): Warning
- [Combination skin](https://lovi.care/skincare/au/p/eucerin/hyaluron-filler-epigenetic-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/au/p/eucerin/hyaluron-filler-epigenetic-serum/for/sensitive-skin): Average (this page)
- [Acne-prone skin](https://lovi.care/skincare/au/p/eucerin/hyaluron-filler-epigenetic-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/au/p/eucerin/hyaluron-filler-epigenetic-serum/for/dark-spots): Low
- [Mature skin](https://lovi.care/skincare/au/p/eucerin/hyaluron-filler-epigenetic-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/au/p/eucerin/hyaluron-filler-epigenetic-serum/for/dry-sensitive-skin): Caution
- [Oily acne-prone skin](https://lovi.care/skincare/au/p/eucerin/hyaluron-filler-epigenetic-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Glycerin, Hyaluronic Acid

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))

## What reviewers say

Based on a very large amount of data, users consistently report that the serum provides an immediate boost of hydration, leaving skin feeling significantly smoother, softer, and more radiant. While many observed a reduction in fine lines and a "plumped" effect within a few weeks, a small minority experienced skin irritation or felt the anti-aging results were not visible enough to justify the price.

- Liked: Lightweight, fast absorption (mostly mentioned)
- Liked: Layers well (often mentioned)
- Liked: Smoother, plumper skin (often mentioned)
- Liked: Pleasant, subtle scent (sometimes noted)
- Liked: Radiant, fresh glow (sometimes noted)
- Disliked: High price point (sometimes noted)
- Disliked: Allergic reactions (rarely noted)
- Disliked: No visible results (rarely noted)
- Disliked: Scent too strong (rarely noted)

## How to apply

- Use this soothing AM and PM routine every day to keep your normal skin calm. Always remember to apply SPF in the morning after your moisturizer.
- Apply your moisturizer after your toner in the morning, and after your serum in the evening. This step locks in hydration and protects your skin.
- Gently press a small amount of the moisturizer evenly across your face. Avoid rubbing to keep your sensitive skin happy and calm.
- You can apply this gentle formula on dry or slightly damp skin for the best comfort. It works wonderfully on clean skin to soothe redness and irritation.
- Do a patch test before your very first use to check your skin's reaction. Avoid getting the product directly into your eyes .
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Eucerin Epigenetic Serum work for sensitive skin?

This serum works reasonably well for sensitive skin, offering moderate moisture with glycerin and hyaluronic acid while panthenol helps calm redness and irritation. It is safe and lacks harsh ingredients, though a moisturizing treatment for this skin needs richer soothing ingredients, optimal hydration, and a well-balanced formula to keep it calm and comfortable.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for sensitive skin?

Glycerin, hyaluronic acid, and panthenol make this serum a good fit for sensitive skin by providing hydration and helping repair the skin barrier to calm redness and irritation. This moisturizing treatment works for sensitive skin, but a product of this type needs to be highly effective in soothing and hydrating with safe concentrations of beneficial ingredients to achieve a top fit.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Water do for sensitive skin?

Using cool water for facial cleansing preserves skin barrier integrity and lowers skin surface pH in healthy adults. This helps keep skin calm and hydrated without causing the irritation associated with warmer water.
Sources: [International Journal of Cosmetic Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42722630/)

### What does Glycerin do for sensitive skin?

Glycerin helps keep sensitive skin soft and deeply hydrated while supporting the skin barrier. It is unlikely to cause irritation and may protect against dryness and roughness.
Sources: [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/), [Acta Dermato-venereologica, 1999](https://pubmed.ncbi.nlm.nih.gov/10598752/)

### Where does this serum go in a skincare routine for sensitive skin?

This serum goes in the evening routine after your soothing toner and before your moisturizer. It works for your sensitive skin, though sensitive skin generally needs products with gentle hydrators like glycerin and hyaluronic acid, barrier-repairing panthenol, and no harsh irritants.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first to help hydrate and calm your skin before the retinol. This product is safe for sensitive skin, but because it is an average fit, sensitive skin often does better with a product that focuses specifically on soothing and restoring the skin barrier with extra calming ingredients.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### How often should I use this serum?

Use this serum in your evening routine as outlined by Lovi, applying it after your cleansing and toning steps. Because it is an average fit for your sensitive skin, this type of product also needs extra soothing and barrier-repairing ingredients to keep your skin calm and hydrated.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this serum clog pores, cause breakouts or purging for sensitive skin?

This serum is unlikely to clog pores or cause breakouts on sensitive skin, as its formula lacks heavy ingredients that typically block pores. It is generally well tolerated, though sensitive skin sometimes reacts to scented formulas or alcohol denat.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Can I use this serum around the eyes or on my body?

This serum is safe to use around the eyes and on the body, though it provides only moderate moisture for these delicate areas. Thin skin requires a moisturizing treatment with rich hydrators and barrier-repairing ingredients to fully protect against dryness and irritation.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Is this serum fragrance-free and alcohol-free?

It contains fragrance (parfum) and drying alcohol (alcohol denat).

## Alternatives for sensitive skin

- [Torriden DIVE-IN Low Molecular Hyaluronic Acid Serum](https://lovi.care/skincare/au/p/torriden/dive-in-low-molecular-hyaluronic-acid-serum/for/sensitive-skin) — High fit — A$26.00 at Amazon
- [COSRX Hydrium Triple Hyaluronic Moisture Ampoule](https://lovi.care/skincare/au/p/cosrx/hydrium-triple-hyaluronic-moisture-ampoule/for/sensitive-skin) — High fit — A$42.40 at Amazon
- [Elizavecca Witch Piggy Hell Pore Control Hyaluronic Acid 97%](https://lovi.care/skincare/au/p/elizavecca/witch-piggy-hell-pore-control-hyaluronic-acid-97/for/sensitive-skin) — High fit — A$25.90 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/au/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — A$73.61 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/au/p/clarins/soothing-toning-lotion/for/sensitive-skin) — Superior fit — A$54.00 at Amazon
- Moisturizer with Sun Protection: [Bioderma Bioderma Photoderm Mineral SPF 50+](https://lovi.care/skincare/au/p/bioderma/photoderm-mineral-fluide-spf50/for/sensitive-skin) — Superior fit — A$24.49 at Amazon

## Where to buy

- Amazon.com.au: A$80.99 (https://www.amazon.com.au/dp/B08HDNW8D6?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
Prices checked 3 Nov 2026.

## Ingredients

Water, Glycerin, Alcohol Denat, Hyaluronic Acid, Epicelline, Panthenol, Glyceryl Glucoside, Sodium Hydroxide, Phenoxyethanol, Parfum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/eucerin/hyaluron-filler-epigenetic-serum/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/eucerin/hyaluron-filler-epigenetic-serum/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/eucerin/hyaluron-filler-epigenetic-serum/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/eucerin/hyaluron-filler-epigenetic-serum/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/eucerin/hyaluron-filler-epigenetic-serum/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/eucerin/hyaluron-filler-epigenetic-serum/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/eucerin/hyaluron-filler-epigenetic-serum/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/eucerin/hyaluron-filler-epigenetic-serum/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/eucerin/hyaluron-filler-epigenetic-serum/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/eucerin/hyaluron-filler-epigenetic-serum/for/sensitive-skin (this page)
- Singapore: https://lovi.care/skincare/sg/p/eucerin/hyaluron-filler-epigenetic-serum/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/eucerin/hyaluron-filler-epigenetic-serum/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/eucerin/hyaluron-filler-epigenetic-serum/for/sensitive-skin