# Eucerin Hyaluron-Filler Epigenetic Serum for oily acne-prone skin

**Lovi Fit: Average fit for oily acne-prone skin.**
Oily Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/au/p/eucerin/hyaluron-filler-epigenetic-serum/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Australia.

Brand: [Eucerin](https://lovi.care/skincare/au/brands/eucerin)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/au/best/moisturizers)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily acne-prone skin; other moisturizers fit it better.

## Why this fit

- Offers excellent moisturizing and plumping for your oily skin due to Hyaluronic Acid and Glycerin, which hydrate and smooth skin texture without causing irritation.
- While beneficial for general hydration and supportive for acne-prone skin, the formula lacks targeted ingredients to directly address your concerns of acne, blemishes, and breakouts.
- The safety profile is excellent, with no risks of irritation for your oily skin due to the absence of harsh ingredients and the presence of soothing components like Panthenol.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/au/p/eucerin/hyaluron-filler-epigenetic-serum/for/oily-skin): Low
- [Dry skin](https://lovi.care/skincare/au/p/eucerin/hyaluron-filler-epigenetic-serum/for/dry-skin): Warning
- [Combination skin](https://lovi.care/skincare/au/p/eucerin/hyaluron-filler-epigenetic-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/au/p/eucerin/hyaluron-filler-epigenetic-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/au/p/eucerin/hyaluron-filler-epigenetic-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/au/p/eucerin/hyaluron-filler-epigenetic-serum/for/dark-spots): Low
- [Mature skin](https://lovi.care/skincare/au/p/eucerin/hyaluron-filler-epigenetic-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/au/p/eucerin/hyaluron-filler-epigenetic-serum/for/dry-sensitive-skin): Caution
- [Oily acne-prone skin](https://lovi.care/skincare/au/p/eucerin/hyaluron-filler-epigenetic-serum/for/oily-acne-prone-skin): Average (this page)

## Key ingredients

Glycerin, Hyaluronic Acid

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))

## Why other moisturizers fit oily acne-prone skin better

- A Tris/Arg-formulated cleanser significantly decreased noninflammatory and inflammatory acne and pore size with keratotic plugs compared to an AEC/AC cleanser in male Thai subjects with mild to moderate acne over 4 weeks. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31347768/))
- Gluconolactone 14% solution significantly improved mild to moderate acne by reducing inflamed and non-inflamed lesions similarly to 5% benzoyl peroxide, but with fewer side-effects in 150 patients. ([The Australasian Journal of Dermatology, 1992](https://pubmed.ncbi.nlm.nih.gov/1303072/))
- A peel-off facial mask containing myoinositol and trehalose-loaded liposomes improved adult female acne by decreasing lesion counts, sebum production, GAGS scores, and local androgen levels while increasing beclin-1 levels. ([Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28342238/))

## What reviewers say

Based on a very large amount of data, users consistently report that the serum provides an immediate boost of hydration, leaving skin feeling significantly smoother, softer, and more radiant. While many observed a reduction in fine lines and a "plumped" effect within a few weeks, a small minority experienced skin irritation or felt the anti-aging results were not visible enough to justify the price.

- Liked: Lightweight, fast absorption (mostly mentioned)
- Liked: Layers well (often mentioned)
- Liked: Smoother, plumper skin (often mentioned)
- Liked: Pleasant, subtle scent (sometimes noted)
- Liked: Radiant, fresh glow (sometimes noted)
- Disliked: High price point (sometimes noted)
- Disliked: Allergic reactions (rarely noted)
- Disliked: No visible results (rarely noted)
- Disliked: Scent too strong (rarely noted)

## How to apply

- Use this AM and PM routine every day to help clear your skin. Always remember to finish with SPF in the morning.
- Apply the moisturizer after your cleanser and toner, right before your SPF during the day.
- Gently press a small amount into your skin and avoid rubbing to keep pores clear.
- Apply on clean, slightly damp skin to help the product absorb better and control oil.
- Avoid the sensitive eye area and do a simple patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Eucerin Hyaluron-Filler Epigenetic Serum work for oily acne-prone skin?

This serum is an average fit for your oily acne-prone skin because it hydrates and smooths your skin without causing irritation, but it lacks targeted ingredients to directly address breakouts. To work better for this skin type, a moisturizing treatment needs ingredients like Niacinamide or ceramides to regulate oil and target blemishes without clogging pores.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Which ingredients make this serum a good fit for oily acne-prone skin?

Hyaluronic Acid and Glycerin make this serum a good fit by hydrating and smoothing your skin without causing irritation, while Panthenol soothes it. It also needs ingredients like Niacinamide to target acne, blemishes, and breakouts, along with pore-balancing components that regulate oil production.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Water do for oily acne-prone skin?

Water helps keep oily, acne-prone skin hydrated without making it greasy. Keeping skin hydrated is important because acne treatments can dry it out and irritate the skin barrier.
Sources: [Journal of Drugs in Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40196957/)

### What does Glycerin do for oily acne-prone skin?

Glycerin helps keep oily acne-prone skin hydrated without feeling heavy. It draws moisture into the skin while supporting the skin barrier so it stays soft and balanced.
Sources: [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Where does this serum go in a skincare routine for oily acne-prone skin?

This treatment goes in the evening routine after cleansing and toning, and before moisturizing. Putting treatments in the evening provides simplicity and extra safety around sun exposure.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first to hydrate your skin and then following with your retinol. This product is unlikely to cause irritation for your oily skin, though an oily acne-prone routine needs a treatment with active ingredients that directly target breakouts and blemishes.

### How often should I use this serum?

You can use this treatment in the evening as part of your routine. Daily application helps keep your oily skin hydrated and smooth without causing irritation.
Sources: [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can this serum clog pores, cause breakouts or purging for oily acne-prone skin?

This serum is unlikely to clog pores or cause irritation on your oily skin due to soothing components like Panthenol and the absence of harsh ingredients, but because it lacks targeted ingredients for blemishes, this skin type needs oil-control agents and blemish-fighting ingredients to properly manage breakouts.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Can I use this serum around the eyes or on my body?

You can use this moisturizing treatment around the eyes and on the body because it provides gentle hydration with very good skin tolerance. To properly care for thin or body skin, this type of product needs hydrating ingredients like hyaluronic acid and glycerin, along with soothing components like panthenol.
Sources: [Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37896378/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is this serum fragrance-free and alcohol-free?

It contains fragrance (parfum) and drying alcohol (alcohol denat).

## Alternatives for oily acne-prone skin

- [Elizavecca Witch Piggy Hell Pore Control Hyaluronic Acid 97%](https://lovi.care/skincare/au/p/elizavecca/witch-piggy-hell-pore-control-hyaluronic-acid-97/for/oily-acne-prone-skin) — Superior fit — A$25.90 at Amazon
- [Torriden DIVE-IN Low Molecular Hyaluronic Acid Serum](https://lovi.care/skincare/au/p/torriden/dive-in-low-molecular-hyaluronic-acid-serum/for/oily-acne-prone-skin) — Superior fit — A$26.00 at Amazon
- [COSRX Hydrium Triple Hyaluronic Moisture Ampoule](https://lovi.care/skincare/au/p/cosrx/hydrium-triple-hyaluronic-moisture-ampoule/for/oily-acne-prone-skin) — High fit — A$42.40 at Amazon

## Pairs well with

- Cleanser: [Paula's Choice CLEAR Pore Normalizing Cleanser](https://lovi.care/skincare/au/p/paula-s-choice/clear-pore-normalizing-cleanser/for/oily-acne-prone-skin) — Superior fit — A$32.00 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/au/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-acne-prone-skin) — Superior fit — A$42.00 at Amazon
- SPF: [La Roche-Posay Anthelios Clear Skin Dry Touch Sunscreen SPF 60](https://lovi.care/skincare/au/p/la-roche-posay/anthelios-clear-skin-dry-touch-sunscreen-spf-60/for/oily-acne-prone-skin) — Superior fit — A$27.99 at Amazon

## Where to buy

- Amazon.com.au: A$80.99 (https://www.amazon.com.au/dp/B08HDNW8D6?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
Prices checked 3 Nov 2026.

## Ingredients

Water, Glycerin, Alcohol Denat, Hyaluronic Acid, Epicelline, Panthenol, Glyceryl Glucoside, Sodium Hydroxide, Phenoxyethanol, Parfum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/eucerin/hyaluron-filler-epigenetic-serum/for/oily-acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/eucerin/hyaluron-filler-epigenetic-serum/for/oily-acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/eucerin/hyaluron-filler-epigenetic-serum/for/oily-acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/eucerin/hyaluron-filler-epigenetic-serum/for/oily-acne-prone-skin
- France: https://lovi.care/skincare/fr/p/eucerin/hyaluron-filler-epigenetic-serum/for/oily-acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/eucerin/hyaluron-filler-epigenetic-serum/for/oily-acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/eucerin/hyaluron-filler-epigenetic-serum/for/oily-acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/eucerin/hyaluron-filler-epigenetic-serum/for/oily-acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/eucerin/hyaluron-filler-epigenetic-serum/for/oily-acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/eucerin/hyaluron-filler-epigenetic-serum/for/oily-acne-prone-skin (this page)
- Singapore: https://lovi.care/skincare/sg/p/eucerin/hyaluron-filler-epigenetic-serum/for/oily-acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/eucerin/hyaluron-filler-epigenetic-serum/for/oily-acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/eucerin/hyaluron-filler-epigenetic-serum/for/oily-acne-prone-skin