# Eucerin Hyaluron-Filler Epigenetic Serum for combination skin

**Lovi Fit: Average fit for combination skin.**
Combination Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/au/p/eucerin/hyaluron-filler-epigenetic-serum/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Australia.

Brand: [Eucerin](https://lovi.care/skincare/au/brands/eucerin)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/au/best/moisturizers)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for combination skin; other moisturizers fit it better.

## Why this fit

- Offers moderate moisturizing for your combination skin, as glycerin and hyaluronic acid provide hydration without exacerbating oiliness. Panthenol further supports skin barrier function and hydration.
- This serum offers general skincare benefits, addressing oily shine by providing essential hydration.
- The safety profile is excellent, with no risks of irritation due to the absence of harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/au/p/eucerin/hyaluron-filler-epigenetic-serum/for/oily-skin): Low
- [Dry skin](https://lovi.care/skincare/au/p/eucerin/hyaluron-filler-epigenetic-serum/for/dry-skin): Warning
- [Combination skin](https://lovi.care/skincare/au/p/eucerin/hyaluron-filler-epigenetic-serum/for/combination-skin): Average (this page)
- [Sensitive skin](https://lovi.care/skincare/au/p/eucerin/hyaluron-filler-epigenetic-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/au/p/eucerin/hyaluron-filler-epigenetic-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/au/p/eucerin/hyaluron-filler-epigenetic-serum/for/dark-spots): Low
- [Mature skin](https://lovi.care/skincare/au/p/eucerin/hyaluron-filler-epigenetic-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/au/p/eucerin/hyaluron-filler-epigenetic-serum/for/dry-sensitive-skin): Caution
- [Oily acne-prone skin](https://lovi.care/skincare/au/p/eucerin/hyaluron-filler-epigenetic-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Glycerin, Hyaluronic Acid

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))

## What reviewers say

Based on a very large amount of data, users consistently report that the serum provides an immediate boost of hydration, leaving skin feeling significantly smoother, softer, and more radiant. While many observed a reduction in fine lines and a "plumped" effect within a few weeks, a small minority experienced skin irritation or felt the anti-aging results were not visible enough to justify the price.

- Liked: Lightweight, fast absorption (mostly mentioned)
- Liked: Layers well (often mentioned)
- Liked: Smoother, plumper skin (often mentioned)
- Liked: Pleasant, subtle scent (sometimes noted)
- Liked: Radiant, fresh glow (sometimes noted)
- Disliked: High price point (sometimes noted)
- Disliked: Allergic reactions (rarely noted)
- Disliked: No visible results (rarely noted)
- Disliked: Scent too strong (rarely noted)

## How to apply

- Use this moisturizer in your AM and PM routine every day to control shine. Always pair with SPF in the morning.
- Apply this moisturizer after your cleanser and toner, right before your morning SPF.
- Gently press a small amount of the moisturizer into your skin and avoid harsh rubbing. Let it ⏳absorb for a minute.
- Apply the moisturizer on slightly damp skin to help it lock in moisture better. This keeps your combination skin balanced.
- Avoid the eye area when applying the moisturizer. Do a patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Hyaluron-Filler Epigenetic Serum work for combination skin?

Eucerin Hyaluron-Filler Epigenetic Serum works moderately well for your combination skin, offering hydration with glycerin and hyaluronic acid without making it oily, while panthenol helps support your skin barrier. A moisturizing treatment for combination skin needs effective hydrating and skin-repairing ingredients that enhance vitality and radiance without causing irritation or excess oiliness, along with components like ceramides to boost moisture retention.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Which ingredients make this serum a good fit for combination skin?

Glycerin and hyaluronic acid make this serum a good fit for your combination skin because they provide essential hydration without making your skin oily, while panthenol helps support your skin barrier. A moisturizing treatment for combination skin needs effective hydrating ingredients that balance moisture levels and control oily shine without causing irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### What does Water do for combination skin?

Water helps keep combination skin hydrated, though a product of this type needs additional barrier-protecting ingredients like ceramides or petrolatum to lock in that moisture and support overall skin health.

### What does Glycerin do for combination skin?

Glycerin helps keep combination skin soft and smooth by pulling moisture in and keeping it there. It improves hydration and supports your skin barrier, which is unlikely to cause irritation.
Sources: [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Where does this serum go in a skincare routine for combination skin?

This serum goes in the evening routine after cleansing and before moisturizing. Putting treatments in the evening helps provide simplicity and extra safety around sun exposure.

### Can I use this serum with retinol, and in what order?

You can use this treatment with retinol by applying the serum before your retinol product. Combination skin needs a product that provides lightweight hydration with glycerin and hyaluronic acid without making oily areas heavier, while panthenol helps keep the skin barrier strong and comfortable.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### How often should I use this serum?

You can use this treatment in the evening as part of your routine. Combination skin needs products with light hydrators and balancing ingredients that deliver moisture without feeling heavy or greasy.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this serum clog pores, cause breakouts or purging for combination skin?

This serum is unlikely to cause breakouts or clog pores on combination skin, as it provides hydration with glycerin and hyaluronic acid without adding heaviness. Its safety profile is excellent with no harsh ingredients, though a product for this skin also needs oil-balancing care to manage shine fully.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this serum around the eyes or on my body?

You can use this serum on the thin skin around your eyes and on your body, as its gentle ingredients are safe and well-tolerated. However, combination skin needs a moisturizing treatment with lightweight hydrators like glycerin and hyaluronic acid plus barrier-supporting panthenol to keep dry areas soft without making oily zones greasy.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is this serum fragrance-free and alcohol-free?

It contains fragrance (parfum) and drying alcohol (alcohol denat).

## Alternatives for combination skin

- [Elizavecca Witch Piggy Hell Pore Control Hyaluronic Acid 97%](https://lovi.care/skincare/au/p/elizavecca/witch-piggy-hell-pore-control-hyaluronic-acid-97/for/combination-skin) — High fit — A$25.90 at Amazon
- [Torriden DIVE-IN Low Molecular Hyaluronic Acid Serum](https://lovi.care/skincare/au/p/torriden/dive-in-low-molecular-hyaluronic-acid-serum/for/combination-skin) — High fit — A$26.00 at Amazon
- [MEDI-PEEL Peptide 9 Volume White Cica All-in-one Essence](https://lovi.care/skincare/au/p/medi-peel/peptide-9-volume-white-cica-all-in-one-essence/for/combination-skin) — High fit — A$38.48 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/au/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — A$73.61 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/au/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — A$42.00 at Amazon
- Pre-Cleanser: [Pyunkang Yul Deep Cleansing Oil](https://lovi.care/skincare/au/p/pyunkang-yul/deep-cleansing-oil/for/combination-skin) — Superior fit — A$30.99 at Amazon

## Where to buy

- Amazon.com.au: A$80.99 (https://www.amazon.com.au/dp/B08HDNW8D6?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
Prices checked 3 Nov 2026.

## Ingredients

Water, Glycerin, Alcohol Denat, Hyaluronic Acid, Epicelline, Panthenol, Glyceryl Glucoside, Sodium Hydroxide, Phenoxyethanol, Parfum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/eucerin/hyaluron-filler-epigenetic-serum/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/eucerin/hyaluron-filler-epigenetic-serum/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/eucerin/hyaluron-filler-epigenetic-serum/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/eucerin/hyaluron-filler-epigenetic-serum/for/combination-skin
- France: https://lovi.care/skincare/fr/p/eucerin/hyaluron-filler-epigenetic-serum/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/eucerin/hyaluron-filler-epigenetic-serum/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/eucerin/hyaluron-filler-epigenetic-serum/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/eucerin/hyaluron-filler-epigenetic-serum/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/eucerin/hyaluron-filler-epigenetic-serum/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/eucerin/hyaluron-filler-epigenetic-serum/for/combination-skin (this page)
- Singapore: https://lovi.care/skincare/sg/p/eucerin/hyaluron-filler-epigenetic-serum/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/eucerin/hyaluron-filler-epigenetic-serum/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/eucerin/hyaluron-filler-epigenetic-serum/for/combination-skin