# Estée Lauder Futurist Peptide-Power Serum Primer for combination skin

**Lovi Fit: High fit for combination skin.**
Combination Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/au/p/estee-lauder/futurist-peptide-power-serum-primer/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Australia.

Brand: [Estée Lauder](https://lovi.care/skincare/au/brands/estee-lauder)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/au/best/moisturizers)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best moisturizers for combination skin.

## Why this fit

- Highly suitable for your combination skin, this serum primer utilizes Acetyl Hexapeptide-8 and Palmitoyl Hexapeptide-12 to support collagen stimulation and extracellular matrix synthesis, addressing your oily shine concerns.
- The inclusion of glycerin and sodium hyaluronate ensures excellent moisturizing and plumping effects, further enhancing the skin's overall appearance.
- The product is safe for your skin, as it contains no harsh ingredients and includes soothing components like whey protein and hyaluronic acid.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/au/p/estee-lauder/futurist-peptide-power-serum-primer/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/au/p/estee-lauder/futurist-peptide-power-serum-primer/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/au/p/estee-lauder/futurist-peptide-power-serum-primer/for/combination-skin): High (this page)
- [Sensitive skin](https://lovi.care/skincare/au/p/estee-lauder/futurist-peptide-power-serum-primer/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/au/p/estee-lauder/futurist-peptide-power-serum-primer/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/au/p/estee-lauder/futurist-peptide-power-serum-primer/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/au/p/estee-lauder/futurist-peptide-power-serum-primer/for/mature-skin): Superior
- [Dry sensitive skin](https://lovi.care/skincare/au/p/estee-lauder/futurist-peptide-power-serum-primer/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/au/p/estee-lauder/futurist-peptide-power-serum-primer/for/oily-acne-prone-skin): Average

## Key ingredients

Acetyl Hexapeptide-8, Palmitoyl Hexapeptide-12, Sodium Hyaluronate, Glycerin, Tetrahexyldecyl Ascorbate

## What the research says

- A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo. ([Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/))
- Hyaluronic acid extracts are safe and efficacious products for skin repair when used in tissue regeneration alone or in combination with herbal or Western medicine. ([Journal of Pharmacy & Pharmaceutical Sciences, 2015](https://pubmed.ncbi.nlm.nih.gov/25877441/))
- Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days. ([Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/))
- Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group. ([American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/))
- Acetyl hexapeptide-3 and tripeptide-10 citrulline demonstrated antiwrinkle efficacy and decreased transepidermal water loss in twenty-four healthy volunteers compared to control groups, though synergistic effects between the two peptides remained unclear. ([Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28150423/))
- Palmitoyl hexapeptide-12 permeates the stratum corneum and epidermis, initiating gel formation via endogenous ions and strengthening and repairing the skin barrier after delipidation in human skin. ([ACS Applied Bio Materials, 2025](https://pubmed.ncbi.nlm.nih.gov/39964201/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))

## What reviewers say

This serum-gel primer is highly praised for its hydrating, plumping, and smoothing effects, making it an excellent choice for mature skin or those seeking a radiant, dewy finish. While it excels at creating a smooth, makeup-ready canvas, some users find the packaging frustrating and the price point high for the amount of product provided.

- Liked: Intense hydration (often mentioned)
- Liked: Radiant finish (often mentioned)
- Liked: Makeup-gripping base (sometimes noted)
- Liked: Smooths fine lines (sometimes noted)
- Disliked: High price/value (sometimes noted)
- Disliked: Poor packaging (sometimes noted)
- Disliked: Heavy/comedogenic concerns (rarely noted)

## How to apply

- Use this moisturizer in your AM and PM routine every day to control shine. Always pair with SPF in the morning.
- Apply this moisturizer after your cleanser and toner, right before your morning SPF.
- Gently press a small amount of the moisturizer into your skin and avoid harsh rubbing. Let it ⏳absorb for a minute.
- Apply the moisturizer on slightly damp skin to help it lock in moisture better. This keeps your combination skin balanced.
- Avoid the eye area when applying the moisturizer. Do a patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes Estée Lauder Futurist Peptide-Power Serum Primer a great fit for combination skin?

This moisturizing treatment is a great fit for your combination skin because it uses peptides to support collagen and help manage oily shine. Glycerin and sodium hyaluronate provide deep moisture and plumping effects, while soothing ingredients keep the skin calm and safe from irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/)

### Which ingredients make this serum a good fit for combination skin?

This serum is a great fit for your combination skin because it uses acetyl hexapeptide-8 and palmitoyl hexapeptide-12 to address oily shine while supporting firmness. It also includes glycerin and sodium hyaluronate to provide deep moisture without feeling heavy, alongside soothing ingredients like whey protein.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/)

### What does Argireline do for combination skin?

Argireline helps smooth out lines and keeps combination skin feeling soft when applied twice daily. This ingredient may reduce wrinkle depth and improve overall skin texture, though its absorption through the skin is quite low.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Journal of Cosmetic and Laser Therapy, 2013](https://pubmed.ncbi.nlm.nih.gov/23607739/)

### What does Palmitoyl Hexapeptide-12 do for combination skin?

Palmitoyl Hexapeptide-12 strengthens and repairs the moisture barrier while keeping combination skin smooth and hydrated. This ingredient helps improve skin elasticity and moisture levels through gentle daily use.
Sources: [ACS Applied Bio Materials, 2025](https://pubmed.ncbi.nlm.nih.gov/39964201/), [Journal of Controlled Release, 2026](https://pubmed.ncbi.nlm.nih.gov/41344485/)

### Where does this serum go in a skincare routine for combination skin?

This treatment goes in the evening routine after cleansing and before moisturizing, though some can also be used in the morning or twice a day. Placing it here keeps things simple and provides extra safety around sun exposure.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first to hydrate and help smooth your skin, followed by your retinol product. Using a hydrating serum underneath helps manage dryness and keeps your skin comfortable while using stronger treatments.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### How often should I use this serum?

This serum primer is suitable for daily use in your evening routine, and some formulas may also be used in the morning or twice a day. Glycerin and sodium hyaluronate help keep your skin well-moisturized, while peptides support collagen and help manage oily shine.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can this serum clog pores, cause breakouts or purging for combination skin?

This serum primer is unlikely to clog pores or cause breakouts on combination skin, as it has a very low risk of feeling heavy and contains no harsh ingredients. Glycerin and sodium hyaluronate help keep skin hydrated without causing congestion.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this serum around the eyes or on my body?

This serum primer is generally safe to use on various skin areas, though the page and studies focus on facial application rather than the body. When applying near the eyes, formulas with peptides and hydrating ingredients like sodium hyaluronate and glycerin are often well-tolerated and help smooth fine lines.
Sources: [Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37896378/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for combination skin

- [Isntree Green Tea Fresh Serum](https://lovi.care/skincare/au/p/isntree/green-tea-fresh-serum/for/combination-skin) — High fit — A$34.00 at Amazon
- [Revision Skincare Hydrating Serum](https://lovi.care/skincare/au/p/revision-skincare/hydrating-serum/for/combination-skin) — High fit — A$97.29 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/au/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — A$73.61 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/au/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — A$42.00 at Amazon
- Pre-Cleanser: [Pyunkang Yul Deep Cleansing Oil](https://lovi.care/skincare/au/p/pyunkang-yul/deep-cleansing-oil/for/combination-skin) — Superior fit — A$30.99 at Amazon

## Where to buy

No store in Australia has a checked price for this product, so the page shows none.

## Ingredients

Water, Butylene Glycol, Glycerin, Acetyl Hexapeptide-8, Palmitoyl Hexapeptide-12, Sodium Pca, Whey Lactis Proteine Du Petit-Lait Protein, Glycine Soja Protein Soybean Protein, Sodium Hyaluronate, Acetyl Glucosamine, Lactobacillus Ferment, Tetrahexyldecyl Ascorbate, Chlorella Vulgaris Extract, Algae Extract, Caprylyl Glycol, Caffeine, Hydrolyzed Rice Extract, Laminaria Digitata Extract, Glucose, Artemia Extract, Sucrose, Peg-8, Xanthan Gum, Sodium Polyacryloyldimethyl Taurate, Calcium Chloride, Glyceryl Polymethacrylate, Sodium Hydroxide, Propanediol, Bht, Tocopheryl Acetate, Disodium Edta, Silica, Phenoxyethanol, Potassium Sorbate, Chlorphenesin, Mica, Titanium Dioxide Ci 77891, Iron Oxides Ci 77492, Bismuth Oxychloride, Carmine
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/estee-lauder/futurist-peptide-power-serum-primer/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/estee-lauder/futurist-peptide-power-serum-primer/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/estee-lauder/futurist-peptide-power-serum-primer/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/estee-lauder/futurist-peptide-power-serum-primer/for/combination-skin
- France: https://lovi.care/skincare/fr/p/estee-lauder/futurist-peptide-power-serum-primer/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/estee-lauder/futurist-peptide-power-serum-primer/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/estee-lauder/futurist-peptide-power-serum-primer/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/estee-lauder/futurist-peptide-power-serum-primer/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/estee-lauder/futurist-peptide-power-serum-primer/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/estee-lauder/futurist-peptide-power-serum-primer/for/combination-skin (this page)
- Singapore: https://lovi.care/skincare/sg/p/estee-lauder/futurist-peptide-power-serum-primer/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/estee-lauder/futurist-peptide-power-serum-primer/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/estee-lauder/futurist-peptide-power-serum-primer/for/combination-skin