# DRMTLGY Needle-less Serum for dry sensitive skin

**Lovi Fit: High fit for dry sensitive skin.**
Dry Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/au/p/drmtlgy/needle-less-serum/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Australia.

Brand: [DRMTLGY](https://lovi.care/skincare/au/brands/drmtlgy)
Category: [Serums and treatments](https://lovi.care/skincare/au/best/serums)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for dry sensitive skin; a few serums fit it even better.

## Why this fit

- Offers excellent plumping and firming for your dry and sensitive skin due to Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, and Palmitoyl Tripeptide-5, which work synergistically to enhance skin elasticity and reduce the appearance of fine lines.
- The inclusion of Sodium Hyaluronate and Glycerin provides significant hydration, addressing your dry or flaky skin concerns by drawing moisture to the surface and improving overall skin texture.
- The formulation is safe for your dry and sensitive skin, as it contains soothing ingredients like Panthenol and Glycerin and lacks harsh or irritating components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/au/p/drmtlgy/needle-less-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/au/p/drmtlgy/needle-less-serum/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/au/p/drmtlgy/needle-less-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/au/p/drmtlgy/needle-less-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/au/p/drmtlgy/needle-less-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/au/p/drmtlgy/needle-less-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/au/p/drmtlgy/needle-less-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/au/p/drmtlgy/needle-less-serum/for/dry-sensitive-skin): High (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/au/p/drmtlgy/needle-less-serum/for/oily-acne-prone-skin): High

## Key ingredients

Sodium Hyaluronate, Niacinamide, Palmitoyl Tripeptide-1, Ceramide Eop, Glycerin

## What the research says

- Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants. ([Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/))
- A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo. ([Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Palmitoyl tetrapeptide-7, acetyl hexapeptide-8, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-10 significantly increased type III collagen levels in human dermal fibroblasts following UV exposure, with their combination demonstrating a greater effect in vitro and enhancing type I, III, and IV collagen levels in ex vivo skin tissues compared to individual components. ([International Journal of Cosmetic Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42683869/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))

## What reviewers say

While many report softer fine lines and improved texture, critical reviews often note that the "needle-less" claim is marketing hyperbole, as the product functions more as a high-quality hydrating peptide serum than a true alternative to injectables.

- Liked: Hydrating and plumping (mostly mentioned)
- Liked: Excellent texture (often mentioned)
- Liked: Sensitive skin friendly (sometimes noted)
- Liked: Softens fine lines (sometimes noted)
- Disliked: No visible results (sometimes noted)
- Disliked: Price point (rarely noted)
- Disliked: Scent and packaging (rarely noted)

## How to apply

- Use this PM routine for your evening skincare. Start using the serum 3 times a week and increase to daily use if your skin feels comfortable.
- Apply the serum after cleansing and toner, but right before your moisturizer. This step locks in deep hydration for dry skin.
- Gently press 2-3 drops of the serum into your skin using your palms. Let it absorb completely for a minute ⏱ before applying your next product.
- Since your skin is sensitive, apply the serum on completely dry skin for better tolerance and less irritation.
- Avoid the sensitive eye area during application. Always do a patch test before your first use to ensure your skin reacts well.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes the Needle-less Serum a great fit for dry sensitive skin?

This serum is a great fit because it plumps and firms your skin with peptides while drawing in deep hydration with sodium hyaluronate and glycerin. It also keeps your delicate skin calm and comfortable by using soothing ingredients like panthenol without any harsh irritants.
Sources: [Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for dry sensitive skin?

This serum is a great fit because Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, and Palmitoyl Tripeptide-5 firm and smooth your dry sensitive skin. Sodium Hyaluronate and Glycerin draw in moisture to stop flaking, while Panthenol and Glycerin calm irritation.
Sources: [Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/), [Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/)

### What does Hyaluronic Acid do for dry sensitive skin?

Hyaluronic acid is a great fit for dry, sensitive skin because it brings a large boost in hydration, making the skin feel soft and smooth while improving barrier function. It helps calm tightness and dryness, and is unlikely to cause irritation.
Sources: [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/), [Dermatology and Therapy, 2021](https://pubmed.ncbi.nlm.nih.gov/34176098/)

### What does Niacinamide do for dry sensitive skin?

Niacinamide helps dry sensitive skin by calming irritation and keeping moisture locked in so your face feels soft and smooth. It works to build up your skin barrier and calm redness while being very gentle and unlikely to cause irritation.
Sources: [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/), [International Journal of Pharmaceutics, 2013](https://pubmed.ncbi.nlm.nih.gov/23220080/)

### Where does this serum go in a skincare routine for dry sensitive skin?

This treatment goes in your evening routine after cleansing and a soothing toner, followed by a moisturizer. Putting treatments in the evening keeps things simple and provides extra safety around sun exposure.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first to keep your dry skin calm and hydrated before layering retinol on top. This routine helps your skin tolerate the retinol while minimizing dryness and irritation.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/)

### How often should I use this serum?

You can use this treatment in the evening as part of your routine for dry and sensitive skin. It helps keep your skin calm while smoothing fine lines and adding moisture.
Sources: [Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/), [Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/)

### Can this serum clog pores, cause breakouts or purging for dry sensitive skin?

This serum is unlikely to clog pores or cause breakouts on dry sensitive skin. Its hydrating ingredients and soothing components are gentle and well-tolerated without harsh elements.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for dry sensitive skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/au/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/dry-sensitive-skin) — Superior fit — A$16.95 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/au/p/augustinus-bader/the-serum/for/dry-sensitive-skin) — Superior fit — A$639.95 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/au/p/neogen-dermalogy/real-vitamin-c-serum/for/dry-sensitive-skin) — High fit — A$50.60 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/au/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — A$19.39 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/au/p/clarins/soothing-toning-lotion/for/dry-sensitive-skin) — Superior fit — A$54.00 at Amazon
- Moisturizer with Sun Protection: [Bioderma Bioderma Photoderm Mineral SPF 50+](https://lovi.care/skincare/au/p/bioderma/photoderm-mineral-fluide-spf50/for/dry-sensitive-skin) — Superior fit — A$24.49 at Amazon

## Where to buy

No store in Australia has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Sodium Chondroitin Sulfate, Sodium Hyaluronate, Pisum Sativum Extract, Bambusa Vulgaris Stem Extract Leaf, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Ceramide Eop, Glucosamine Hcl, Glycosaminoglycans, Ceramide Np, Palmitoyl Tripeptide-5, Ceramide Ap, Phytosphingosine, Cholesterol, Niacinamide, Sodium Lauroyl Lactylate, Methylglucoside Phosphate, Copper Lysinate Prolinate, Panthenol, Phenoxyethanol, Ethylhexylglycerin, Polysorbate 20, Disodium Edta, Butylene Glycol, Carbomer, Xanthan Gum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/drmtlgy/needle-less-serum/for/dry-sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/drmtlgy/needle-less-serum/for/dry-sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/drmtlgy/needle-less-serum/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/drmtlgy/needle-less-serum/for/dry-sensitive-skin
- France: https://lovi.care/skincare/fr/p/drmtlgy/needle-less-serum/for/dry-sensitive-skin
- Italy: https://lovi.care/skincare/it/p/drmtlgy/needle-less-serum/for/dry-sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/drmtlgy/needle-less-serum/for/dry-sensitive-skin
- Spain: https://lovi.care/skincare/es/p/drmtlgy/needle-less-serum/for/dry-sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/drmtlgy/needle-less-serum/for/dry-sensitive-skin
- Australia: https://lovi.care/skincare/au/p/drmtlgy/needle-less-serum/for/dry-sensitive-skin (this page)
- Singapore: https://lovi.care/skincare/sg/p/drmtlgy/needle-less-serum/for/dry-sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/drmtlgy/needle-less-serum/for/dry-sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/drmtlgy/needle-less-serum/for/dry-sensitive-skin