Dermalogica Stress Positive Eye Lift for skin with dark spots

Questions and answers

What the research says

• Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer.

  The British Journal of Dermatology, 2002

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• Profhilo treatment led to significant improvements in superficial skin hydration and transepidermal water loss over time in Chinese females, while demonstrating good product tolerability.

  Aesthetic Plastic Surgery, 2026

• Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.

  Journal of Cosmetic Dermatology, 2021

• Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.

  The Journal of Investigative Dermatology, 2008

• Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.

  Dermatologic Surgery, 2005

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• Clay jojoba oil facial masks reduced total skin lesions by a mean of 54% after 6 weeks in 133 participants with acne-prone, lesioned skin and mild acne compared to baseline.

  Forschende Komplementarmedizin, 2012

• Topical application of jojoba wax reduced LPS-induced secretion of IL-6, IL-8, and TNFα by approximately 30% and increased the synthesis of pro-collagen III and hyaluronic acid compared to untreated skin in an ex-vivo human skin organ culture model.

  Frontiers in Pharmacology, 2024

• Topical jojoba oil application in male mice decreased exercise-induced pro-inflammatory gene expression (Il-1b and Il-6 in soleus, Il-1b in gastrocnemius) compared to untreated exercised mice.

  Biomolecules, 2025

• Diglucosyl gallic acid exhibits stronger tyrosinase inhibition than VC with an IC50 of 2.68 mg/mL, and its application as a cosmetic ingredient improves skin brightness while reducing ultraviolet spots, melanin, and erythema in human volunteers.

  International Journal of Cosmetic Science, 2022

• Topical moisturizers improved skin barrier function and surface moisture, while a postbiotic moisturizer with yeast extract uniquely supported microbiome balance and modulated biomarkers of skin barrier, structure, and inflammation in participants and ex vivo explants exposed to environmental aggressors.

  Journal of Clinical Medicine, 2023

• A maintenance therapy with a cosmeceutical formulation containing hydroxyphenoxy propionic acid, ellagic acid, yeast extract, and salicylic acid over 20 weeks significantly improved even skin tone, spot intensity, spot size, and overall hyperpigmentation in 33 healthy subjects with moderate facial dyspigmentation.

  Journal of Drugs in Dermatology, 2015

• A methanol yeast extract increases proliferation and migration while decreasing entrance into senescence and apoptosis phases in 3T3 fibroblast cells.

  Journal of Cosmetic Science, 2014

Ingredients

Water, Dimethicone, Pentylene Glycol, Sorbitol, Jojoba Seed Oil, Butylene Glycol, Glycerin, Peg-40 Hydrogenated Castor Oil, Saccharomyces Lysate Ferment Filtrate, Tephrosia Purpurea Seed Extract, Hydrolyzed Sodium Hyaluronate, Niacinamide, Diglucosyl Gallic Acid, Citrus Reticulata Oil Leaf Tangerine Oil Leaf, Ammonium Acryloyldimethyltaurate Vp Copolymer, Sea Water, Propanediol, Sodium Hyaluronate, Vetiveria Zizanoides Oil Root, Lavandula Angustifolia Oil Lavender Oil, Rosa Damascena Oil Flower, Salvia Sclarea Oil, Hydrolyzed Algin, Rosewood Oil Wood, Cananga Odorata Oil Flower, Glyceryl Stearate Se, Methyl Lactate, Peg-100 Stearate, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Tocopherol, Sucrose, Caprylic Capric Triglyceride, Ethylhexylglycerin, Sodium Hydroxide, Tetrasodium Glutamate Diacetate, Aminomethyl Propanol, Xanthan Gum, Linalool, Geraniol, Phenoxyethanol

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.