# CLEARSTEM CELLRENEW Serum for oily acne-prone skin

**Lovi Fit: Average fit for oily acne-prone skin.**
Oily Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/au/p/clearstem/cellrenew-serum/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Australia.

Brand: [CLEARSTEM](https://lovi.care/skincare/au/brands/clearstem)
Category: [Serums and treatments](https://lovi.care/skincare/au/best/serums)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily acne-prone skin; other serums fit it better.

## Why this fit

- Highly suitable for your oily skin due to the presence of Camellia Sinensis and Ganoderma Lucidum, which offer antioxidant and seboregulation properties to help manage oiliness.
- The serum provides excellent hydration and protection with antioxidants and sodium hyaluronate, though its benefits for your acne, blemishes, and breakouts are supportive rather than targeted.
- The safety profile is excellent, with no risks of irritation for your oily skin due to the absence of harsh ingredients and the inclusion of soothing agents like Camellia Sinensis and Aloe Barbadensis.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/au/p/clearstem/cellrenew-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/au/p/clearstem/cellrenew-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/au/p/clearstem/cellrenew-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/au/p/clearstem/cellrenew-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/au/p/clearstem/cellrenew-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/au/p/clearstem/cellrenew-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/au/p/clearstem/cellrenew-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/au/p/clearstem/cellrenew-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/au/p/clearstem/cellrenew-serum/for/oily-acne-prone-skin): Average (this page)

## Key ingredients

Sodium Hyaluronate, Ganoderma Lucidum, Bio-Available Collagen Cells Stem, Antioxidants, Curcuma Longa

## What the research says

- Epigallocatechin-3-gallate significantly improved acne in patients compared to the control side during an 8-week clinical trial. ([The Journal of Investigative Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23096708/))
- Topical application of (-)-epigallocatechin-3-gallate (EGCG) to human skin before UV irradiation decreases UV-induced production of hydrogen peroxide by 68-90% and nitric oxide by 30-100%, inhibits leukocyte infiltration and lipid peroxidation by 41-84%, and restores glutathione levels and glutathione peroxidase activity compared to UV exposure alone. ([Carcinogenesis, 2001](https://pubmed.ncbi.nlm.nih.gov/11181450/))
- Small extracellular vesicles derived from Aloe vera peels exhibited antioxidant activity, reduced intracellular ROS levels, enhanced human skin cell migration, and upregulated antioxidant-related gene expression in H2O2-treated human keratinocytes. ([Tissue Engineering and Regenerative Medicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34313971/))
- Topical epigallocatechin-3-gallate application and zonal priming reduced scar thickness and VEGFA, decreased mast cells, increased M2 macrophages and hydration, and improved elasticity compared with placebo in human scars. ([The Journal of Investigative Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30822414/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical application of soap enriched with Ganoderma lucidum and goat's milk for 3 days resulted in almost complete regression of annular cutaneous sarcoidosis lesions in a 44-year-old male patient. ([Dermatology and Therapy, 2016](https://pubmed.ncbi.nlm.nih.gov/26868374/))
- Ganoderma lucidum polysaccharides at concentrations of 10, 20, and 40 ΓΖg/mL significantly increased fibroblast viability, migration, and CICP and TGF-Β1 expression compared to the control group, and external use in mice significantly increased wound healing rates and reduced healing time. ([Chinese Journal of Integrative Medicine, 2019](https://pubmed.ncbi.nlm.nih.gov/30552545/))
- Ethanolic extracts of Ganoderma lucidum rich in triterpenoids and phenolic acids exhibit antioxidant, anti-inflammatory, antityrosinase, antimicrobial, and cytotoxic effects, and can be successfully incorporated into topical cosmeceutical formulations while preserving their bioactivities. ([Food and Chemical Toxicology, 2017](https://pubmed.ncbi.nlm.nih.gov/28760544/))
- Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35818134/))
- Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks. ([International Journal of Molecular Sciences, 2022](https://pubmed.ncbi.nlm.nih.gov/35163025/))
- Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers. ([Marine Drugs, 2023](https://pubmed.ncbi.nlm.nih.gov/36827098/))
- Topical application of curcumin or turmeric treats various skin conditions by leveraging antioxidant, anti-inflammatory, and antimicrobial properties. ([Skin Pharmacology and Physiology, 2023](https://pubmed.ncbi.nlm.nih.gov/38008088/))
- Topical formulations of curcumin target oxidative damage and inflammation to improve wound healing in animal models. ([Drug Discovery Today, 2017](https://pubmed.ncbi.nlm.nih.gov/28711364/))
- A curcumin-loaded spanlastic anti-aging gel utilizing formula F5 incorporated into 2% HPMC E50 demonstrated sustained release action, compatibility, and the ability to penetrate skin layers to a depth of about 112.5 um without signs of irritation. ([Saudi Pharmaceutical Journal, 2024](https://pubmed.ncbi.nlm.nih.gov/38178851/))

## Why other serums fit oily acne-prone skin better

- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo. ([BioMed Research International, 2022](https://pubmed.ncbi.nlm.nih.gov/35342760/))

## What reviewers say

Based on a very large amount of data, users with acne-prone, sensitive, and reactive skin highly praise this product for calming inflammation, improving hydration, and supporting skin barrier repair. Many report smoother texture and reduced redness. Some users note it is a gentle, long-term support product rather than an overnight solution for deep-seated skin concerns.

- Liked: Acne-safe formula (mostly mentioned)
- Liked: Calms inflammation (often mentioned)
- Liked: Improves skin texture (often mentioned)
- Liked: Deeply hydrating (sometimes noted)
- Disliked: High price point (sometimes noted)
- Disliked: Slow visible results (sometimes noted)
- Disliked: Insufficient for severe acne (rarely noted)

## How to apply

- Could be used as part of your PM routine. Start 3 times a week and build up to daily use if your skin tolerates it well.
- Apply your serum after cleansing and toning, but before putting on your moisturizer.
- Gently press 2 to 3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on clean, dry skin to help manage your blemishes safely.
- Do a patch test before your first use and avoid the delicate eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does CLEARstem CELLRENEW Serum work for oily acne-prone skin?

This serum works moderately well for oily acne-prone skin, as it manages oil and provides hydration with a very safe, soothing formula, though its support for breakouts is secondary. To fit this skin type best, treatments need targeted blemish-fighting ingredients like niacinamide, propolis, or Vitamin C alongside oil-controlling components.
Sources: [The Journal of Investigative Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23096708/), [Carcinogenesis, 2001](https://pubmed.ncbi.nlm.nih.gov/11181450/)

### Which ingredients make this serum a good fit for oily acne-prone skin?

Camellia Sinensis and Ganoderma Lucidum make this serum a good fit for oily skin because they help manage oiliness and provide antioxidant protection. To fit oily acne-prone skin even better, a treatment of this type needs ingredients like niacinamide, propolis, or Vitamin C that actively target acne and blemishes while keeping skin comfortable and balanced.
Sources: [The Journal of Investigative Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23096708/), [Carcinogenesis, 2001](https://pubmed.ncbi.nlm.nih.gov/11181450/)

### What does Hyaluronic Acid do for oily acne-prone skin?

Hyaluronic acid helps calm oily acne-prone skin by reducing sebum production and lipid synthesis in sebaceous glands. It also supports skin barrier function and improves hydration while helping deliver treatments without causing irritation.
Sources: [The Journal of Investigative Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28163068/), [Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35796638/)

### What does Reishi Mushroom Extract do for oily acne-prone skin?

Reishi Mushroom Extract helps calm oily, acne-prone skin by soothing inflammation and protecting against damage that can worsen breakouts. It also improves overall skin quality to keep your face looking clear and healthy.
Sources: [Advances in Experimental Medicine and Biology, 2019](https://pubmed.ncbi.nlm.nih.gov/31777026/), [Fitoterapia, 2025](https://pubmed.ncbi.nlm.nih.gov/40381851/)

### Where does this serum go in a skincare routine for oily acne-prone skin?

This treatment goes in the evening routine after cleansing and before moisturizing. Products of this type work best for this skin when they include targeted acne-fighting ingredients like salicylic acid or benzoyl peroxide.

### Can I use it with retinol, and in what order?

Yes, you can use this treatment with retinol in your evening routine, applying the treatment after your cleansing toner and before your moisturizer. To best care for oily acne-prone skin, this type of product also needs targeted blemish-fighting ingredients and oil-balancing agents.

### How often should I use this serum?

You can use this serum in your evening routine, applying it after cleansing and before moisturizing. This skincare product is unlikely to cause irritation on your oily skin.

### Can it clog pores, cause breakouts or purging for oily acne-prone skin?

This serum is unlikely to cause breakouts or clog pores on oily skin because it lacks harsh ingredients and includes soothing aloe and green tea, though its effects on your acne are only supportive. To truly clear blemishes and breakouts, this skin type needs targeted blemish-fighting ingredients like salicylic acid or benzoyl peroxide.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for oily acne-prone skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/au/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/oily-acne-prone-skin) — Superior fit — A$16.95 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/au/p/neogen-dermalogy/real-vitamin-c-serum/for/oily-acne-prone-skin) — Superior fit — A$50.60 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/au/p/neogen-dermalogy/real-vita-c-serum/for/oily-acne-prone-skin) — High fit — A$50.60 at Amazon

## Pairs well with

- Cleanser: [Paula's Choice CLEAR Pore Normalizing Cleanser](https://lovi.care/skincare/au/p/paula-s-choice/clear-pore-normalizing-cleanser/for/oily-acne-prone-skin) — Superior fit — A$32.00 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/au/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-acne-prone-skin) — Superior fit — A$42.00 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/au/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/oily-acne-prone-skin) — Superior fit — A$22.99 at Amazon

## Where to buy

No store in Australia has a checked price for this product, so the page shows none.

## Ingredients

Antioxidants, Camellia Sinensis, Sodium Hyaluronate, Ganoderma Lucidum, Curcuma Longa, Trifolium Pratense, Peppermint Essence, Curcuma Extract, Aloe Barbadensis, Panthenol B5, Bio-Available Collagen Cells Stem, Kunzea Pomifera Fruit Extract
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/clearstem/cellrenew-serum/for/oily-acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/clearstem/cellrenew-serum/for/oily-acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/clearstem/cellrenew-serum/for/oily-acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/clearstem/cellrenew-serum/for/oily-acne-prone-skin
- France: https://lovi.care/skincare/fr/p/clearstem/cellrenew-serum/for/oily-acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/clearstem/cellrenew-serum/for/oily-acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/clearstem/cellrenew-serum/for/oily-acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/clearstem/cellrenew-serum/for/oily-acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/clearstem/cellrenew-serum/for/oily-acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/clearstem/cellrenew-serum/for/oily-acne-prone-skin (this page)
- Singapore: https://lovi.care/skincare/sg/p/clearstem/cellrenew-serum/for/oily-acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/clearstem/cellrenew-serum/for/oily-acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/clearstem/cellrenew-serum/for/oily-acne-prone-skin