# Clean & Clear Persa-Gel 10 for dry skin

**Lovi Fit: Low fit for dry skin.**
Dry Skin Fit: Low · Effectiveness: Average · Safety: Concerning.

Page: https://lovi.care/skincare/au/p/clean-and-clear/persa-gel-10/for/dry-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Australia.

Brand: [Clean & Clear](https://lovi.care/skincare/au/brands/clean-and-clear)
Category: [Serums and treatments](https://lovi.care/skincare/au/best/serums)

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A weak match for dry skin; the serums alongside fit it better.

## Why this fit

- Offers moderate treatment for acne-prone skin as benzoyl peroxide helps reduce acne lesions, but it may be too drying for your dry skin due to a lack of sufficient emollient and humectant ingredients.
- While benzoyl peroxide provides moderate exfoliation for dry or flaky skin, its drying nature can potentially worsen flakiness.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/au/p/clean-and-clear/persa-gel-10/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/au/p/clean-and-clear/persa-gel-10/for/dry-skin): Low (this page)
- [Combination skin](https://lovi.care/skincare/au/p/clean-and-clear/persa-gel-10/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/au/p/clean-and-clear/persa-gel-10/for/sensitive-skin): Low
- [Acne-prone skin](https://lovi.care/skincare/au/p/clean-and-clear/persa-gel-10/for/acne-prone-skin): Superior
- [Skin with dark spots](https://lovi.care/skincare/au/p/clean-and-clear/persa-gel-10/for/dark-spots): Low
- [Mature skin](https://lovi.care/skincare/au/p/clean-and-clear/persa-gel-10/for/mature-skin): Low
- [Dry sensitive skin](https://lovi.care/skincare/au/p/clean-and-clear/persa-gel-10/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/au/p/clean-and-clear/persa-gel-10/for/oily-acne-prone-skin): Superior

## Key ingredients

Benzoyl Peroxide, Carbomer Homopolymer Type B, Hydroxypropyl Methylcellulose, Sodium Hydroxide

## What the research says

- Topical benzoyl peroxide may improve acne more effectively than placebo or no treatment, while showing little to no difference compared with adapalene or clindamycin, but with an increased risk of treatment discontinuation due to adverse effects compared to placebo. ([The Cochrane Database of Systematic Reviews, 2020](https://pubmed.ncbi.nlm.nih.gov/32175593/))
- Once-daily fixed-dose clindamycin phosphate 1.2%/benzoyl peroxide 3.1%/adapalene 0.15% gel achieved superior treatment success (52.5%) and greater reductions in inflammatory and noninflammatory lesions compared to vehicle (8.1%) and dyad component gels in participants with moderate-to-severe acne over 12 weeks. ([American Journal of Clinical Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34674160/))
- Twice daily application of a multitargeted dermocosmetic cream provided comparable efficacy to benzoyl peroxide 5% gel in reducing inflammatory, non-inflammatory, and total lesions in 150 Caucasian subjects with mild-to-moderate acne over 56 days, while demonstrating superior skin tolerability. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/))
- Topical clindamycin phosphate 1.2%/adapalene 0.15%/benzoyl peroxide 3.1% gel achieved significantly greater treatment success and lesion reductions compared to vehicle in participants with moderate-to-severe acne. ([Journal of the American Academy of Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37656094/))
- Daily application of adapalene 0.3%/benzoyl peroxide 2.5% gel reduced and prevented atrophic acne scar formation, achieving a total scar count change of -15.5% versus +14.4% for vehicle over 24 weeks in 67 subjects with moderate or severe facial acne. ([American Journal of Clinical Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29549588/))
- Topical chloramphenicol-betamethasone combined with sodium hyaluronate/trehalose/carbomer gel compared to chloramphenicol-betamethasone alone reduced most subjective symptoms at 1 week but increased blurred vision at 4 weeks following strabismus surgery in 31 patients, with no significant differences in conjunctival inflammation between treatments. ([Journal of Ocular Pharmacology and Therapeutics, 2019](https://pubmed.ncbi.nlm.nih.gov/31298607/))
- Incorporating nanoemulsions into hydrogels with increasing Carbopol 934 proportions from 1% to 3% progressively decreased the percutaneous flux rates of terbinafine and citral, increased drug accumulation in the stratum corneum while decreasing it in the epidermis/dermis compared to nanoemulsions alone, and shifted delivery routes from skin appendages to intercellular paths. ([International Journal of Nanomedicine, 2016](https://pubmed.ncbi.nlm.nih.gov/27877042/))
- Topical liquiritin carbomer gel treatment restored skin barrier function, increased barrier proteins and antioxidant enzymes, and decreased inflammatory cytokines and oxidative stress in a mouse model of glucocorticoid-induced skin inflammation. ([Pharmaceutics, 2024](https://pubmed.ncbi.nlm.nih.gov/39204346/))
- Biodegradable wound dressings functionalized with silver nanoparticles showed >99% pathogen growth inhibition, bactericidal effects, free radical scavenging, reduced inflammatory response in macrophages, and accelerated wound healing in animals. ([International Journal of Biological Macromolecules, 2022](https://pubmed.ncbi.nlm.nih.gov/35780920/))
- Hydroxypropyl methylcellulose hydrogel formulations of berberine chloride-loaded escinosomes increased skin residence time and transdermal permeability while maintaining high safety and biocompatibility without skin irritation. ([International Journal of Biological Macromolecules, 2020](https://pubmed.ncbi.nlm.nih.gov/32682035/))

## Why other serums fit dry skin better

- A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/))
- Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days. ([Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/))

## What reviewers say

Based on a very large amount of data, users consistently praise this maximum-strength benzoyl peroxide gel as a highly effective and affordable spot treatment for stubborn acne and cystic bumps. Because of its potency, it frequently causes significant dryness and peeling, making it best suited for oily skin types or targeted application rather than all-over use.

- Liked: Affordable price (mostly mentioned)
- Disliked: Excessive drying (mostly mentioned)
- Liked: Clears pimples (often mentioned)
- Liked: Effective spot treatment (often mentioned)
- Disliked: Bleaches fabrics (often mentioned)
- Disliked: Causes burning (sometimes noted)

## How to apply

- Apply this serum PM, starting 3×/week and working up to daily use as your skin adjusts.
- Place the serum after cleansing and toner, but right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on slightly damp skin to help lock in extra moisture.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### Why is Clean & Clear Persa-Gel 10 a weak match for dry skin?

Clean & Clear Persa-Gel 10 is a weak match for your dry skin because benzoyl peroxide may be too drying due to a lack of sufficient softening and moisture-binding ingredients, and its drying nature can potentially worsen flakiness. A treatment for dry skin needs soothing ingredients, ceramides, niacinamide, propolis, or peptides that provide significant hydration, support skin health, and improve skin texture without any risk of irritation.
Sources: [The Cochrane Database of Systematic Reviews, 2020](https://pubmed.ncbi.nlm.nih.gov/32175593/), [American Journal of Clinical Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34674160/)

### Which ingredients make this treatment a poor fit for dry skin?

This treatment is a weak match for your dry skin because it lacks enough ingredients that add moisture and hold water, which makes the benzoyl peroxide too drying and likely to worsen flakiness. A treatment for dry skin needs soothing and hydrating ingredients like propolis, niacinamide, ceramides, vitamin C, bifida fermentation, and peptides to nourish and support the skin barrier without irritation.
Sources: [The Cochrane Database of Systematic Reviews, 2020](https://pubmed.ncbi.nlm.nih.gov/32175593/)

### What does Benzoyl Peroxide do for dry skin?

Benzoyl peroxide is usually a poor fit for dry skin because it tends to cause bothersome dryness, peeling, and irritation. When treating dry skin with acne, a product of this type needs soothing ingredients like ceramides and gentle, hydrating cleansers to protect the skin barrier.
Sources: [Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37276158/), [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/21637901/)

### What does Water do for dry skin?

Drinking more water helps increase skin hydration and may reduce clinical signs of dryness and roughness, particularly for individuals with lower prior water consumption.
Sources: [Skin Research and Technology, 2018](https://pubmed.ncbi.nlm.nih.gov/29392767/)

### Where does this treatment go in a skincare routine for dry skin?

This treatment goes in the evening routine after cleansing and before moisturizing, though it may be too drying for your dry skin. A product for this skin needs plenty of soothing moisturizers and water-attracting ingredients to keep it soft and calm.

### Can I use this treatment with retinol, and in what order?

It is best not to use this strong acne treatment at the same time as retinol on dry skin, because using them together is likely to cause extreme dryness and irritation. If you choose to use both, apply your retinol on different nights or use this treatment carefully in your evening routine followed by a rich moisturizer to protect your dry skin.
Sources: [American Family Physician, 2012](https://pubmed.ncbi.nlm.nih.gov/23062156/), [The Cochrane Database of Systematic Reviews, 2020](https://pubmed.ncbi.nlm.nih.gov/32175593/)

### How often should I use this treatment?

Clean & Clear Persa-Gel 10 is used in the evening, starting once a week, because it may be too drying for your dry skin. A product of this type needs soothing and hydrating ingredients to keep dry skin soft, smooth, and calm.
Sources: [The Cochrane Database of Systematic Reviews, 2020](https://pubmed.ncbi.nlm.nih.gov/32175593/)

### Can this treatment clog pores, cause breakouts or purging for dry skin?

This treatment is unlikely to clog pores, but it may cause excessive dryness and worsen flakiness on dry skin. To work well for dry skin, a product of this type needs moisturizing ingredients that soothe and hydrate.

### Is this treatment fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (benzyl alcohol).

## Alternatives for dry skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/au/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/dry-skin) — Superior fit — A$16.95 at Amazon
- [ma:nyo Bifida Biome Complex Ampoule](https://lovi.care/skincare/au/p/ma-nyo/bifida-biome-complex-ampoule/for/dry-skin) — Superior fit — A$29.00 at Amazon
- [KraveBeauty Great Barrier Relief](https://lovi.care/skincare/au/p/kravebeauty/great-barrier-relief/for/dry-skin) — Superior fit — A$75.11 at Amazon

## Routine for dry skin

### AM

- Cleanser: [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/au/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/dry-skin) — Superior fit — A$26.59 at Amazon
- Hydrating Toner: [Pyunkang Yul Calming Deep Moisture Toner](https://lovi.care/skincare/au/p/pyunkang-yul/calming-deep-moisture-toner/for/dry-skin) — Superior fit — A$23.99 at Amazon
- Moisturizer: [d'Alba First Spray Serum](https://lovi.care/skincare/au/p/d-alba/first-spray-serum/for/dry-skin) — Superior fit — A$26.09 at Amazon
- SPF: [Bioderma Bioderma Photoderm Mineral SPF 50+](https://lovi.care/skincare/au/p/bioderma/photoderm-mineral-fluide-spf50/for/dry-skin) — Superior fit — A$24.49 at Amazon

### PM

- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/au/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — A$27.35 at Amazon
- Cleanser: [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/au/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/dry-skin) — Superior fit — A$26.59 at Amazon
- Serum or Treatment: [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/au/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/dry-skin) — Superior fit — A$16.95 at Amazon
- Moisturizer: [d'Alba First Spray Serum](https://lovi.care/skincare/au/p/d-alba/first-spray-serum/for/dry-skin) — Superior fit — A$26.09 at Amazon

### Weekly

- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/au/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — A$27.35 at Amazon
- Cleanser: [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/au/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/dry-skin) — Superior fit — A$26.59 at Amazon
- Enzyme Powder: [Fancl Facial Washing Powder](https://lovi.care/skincare/au/p/fancl/facial-washing-powder/for/dry-skin) — High fit — A$35.50 at Amazon
- Nourishing Mask: [MEDIHEAL Vita Essential Mask](https://lovi.care/skincare/au/p/mediheal/vita-essential-mask/for/dry-skin) — Superior fit — A$28.48 at Amazon
- Serum or Treatment: [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/au/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/dry-skin) — Superior fit — A$16.95 at Amazon
- Moisturizer: [d'Alba First Spray Serum](https://lovi.care/skincare/au/p/d-alba/first-spray-serum/for/dry-skin) — Superior fit — A$26.09 at Amazon

## Where to buy

- Amazon.com.au: A$29.99 (https://www.amazon.com.au/dp/B004RR6MI6?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Benzoyl Peroxide, Water, Carbomer Homopolymer Type B, Hydroxypropyl Methylcellulose, Sodium Hydroxide, Laureth-4, Disodium Edta, Benzyl Alcohol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/clean-and-clear/persa-gel-10/for/dry-skin
- United Kingdom: https://lovi.care/skincare/uk/p/clean-and-clear/persa-gel-10/for/dry-skin
- Ireland: https://lovi.care/skincare/ie/p/clean-and-clear/persa-gel-10/for/dry-skin
- Germany: https://lovi.care/skincare/de/p/clean-and-clear/persa-gel-10/for/dry-skin
- France: https://lovi.care/skincare/fr/p/clean-and-clear/persa-gel-10/for/dry-skin
- Italy: https://lovi.care/skincare/it/p/clean-and-clear/persa-gel-10/for/dry-skin
- Netherlands: https://lovi.care/skincare/nl/p/clean-and-clear/persa-gel-10/for/dry-skin
- Spain: https://lovi.care/skincare/es/p/clean-and-clear/persa-gel-10/for/dry-skin
- Canada: https://lovi.care/skincare/ca/p/clean-and-clear/persa-gel-10/for/dry-skin
- Australia: https://lovi.care/skincare/au/p/clean-and-clear/persa-gel-10/for/dry-skin (this page)
- Singapore: https://lovi.care/skincare/sg/p/clean-and-clear/persa-gel-10/for/dry-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/clean-and-clear/persa-gel-10/for/dry-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/clean-and-clear/persa-gel-10/for/dry-skin