# CELL BY CELL Soft Enzyme Powder for combination skin

**Lovi Fit: Average fit for combination skin.**
Combination Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/au/p/cell-by-cell/soft-enzyme-powder/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Australia.

Brand: CELL BY CELL
Category: [Exfoliants](https://lovi.care/skincare/au/best/exfoliators)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for combination skin; other products fit it better.

## Why this fit

- Offers moderate cleansing for your combination skin, as Sodium Cocoyl Isethionate and Sodium Lauroyl Glutamate help remove impurities without causing irritation. Aloe Barbadensis Leaf Juice and Sorbitol provide some humectant action, but the formula lacks specialized ingredients to effectively manage oily shine.
- The product is safe for your skin due to the absence of harsh or prohibited ingredients, ensuring no risks of irritation.
- It provides general cleansing benefits suitable for combination skin, though it does not specifically target oiliness.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/au/p/cell-by-cell/soft-enzyme-powder/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/au/p/cell-by-cell/soft-enzyme-powder/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/au/p/cell-by-cell/soft-enzyme-powder/for/combination-skin): Average (this page)
- [Sensitive skin](https://lovi.care/skincare/au/p/cell-by-cell/soft-enzyme-powder/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/au/p/cell-by-cell/soft-enzyme-powder/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/au/p/cell-by-cell/soft-enzyme-powder/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/au/p/cell-by-cell/soft-enzyme-powder/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/au/p/cell-by-cell/soft-enzyme-powder/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/au/p/cell-by-cell/soft-enzyme-powder/for/oily-acne-prone-skin): Average

## Key ingredients

Sodium Cocoyl Isethionate, Aloe Barbadensis Leaf Juice, Collagen, Allantoin, Opuntia Ficus-Indica Stem Extract

## What the research says

- Exogenous sorbitol protected epidermal keratinocytes from osmotic toxicity in vitro and significantly improved skin barrier repair and moisturization in individuals in arid environments. ([Journal of Cosmetic Science, 2013](https://pubmed.ncbi.nlm.nih.gov/23752031/))
- Sodium cocoyl isethionate micelles are too large to penetrate stratum corneum aqueous pores, resulting in significant steric hindrance that prevents skin barrier perturbation and explains its skin mildness. ([Journal of Cosmetic Science, 2007](https://pubmed.ncbi.nlm.nih.gov/17598025/))
- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Topical aloe vera gel significantly accelerated split-thickness skin graft donor-site healing compared to placebo in 12 patients, but showed no significant difference in pain relief. ([Plastic and Reconstructive Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29649056/))
- Topical application of Aloe vera cream reduced postoperative pain at rest and during defecation, accelerated wound healing at two weeks, and decreased analgesic requirements in patients after open hemorrhoidectomy compared to placebo. ([Journal of Alternative and Complementary Medicine, 2010](https://pubmed.ncbi.nlm.nih.gov/20569031/))
- Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35818134/))
- Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks. ([International Journal of Molecular Sciences, 2022](https://pubmed.ncbi.nlm.nih.gov/35163025/))
- Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers. ([Marine Drugs, 2023](https://pubmed.ncbi.nlm.nih.gov/36827098/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))
- Opuntia ficus-indica extract and its isorhamnetin-glucosyl-rhamnoside suppressed nitric oxide, COX-2, TNF-alpha, and IL-6 production in vitro and inhibited croton oil-induced ear edema in vivo. ([BioMed Research International, 2015](https://pubmed.ncbi.nlm.nih.gov/25821823/))
- Opuntia ficus-indica extract activated AHR-NRF2 signaling, inhibited reactive oxygen species generation, and upregulated filaggrin and loricrin expression in human keratinocytes. ([Journal of Medicinal Food, 2015](https://pubmed.ncbi.nlm.nih.gov/26061570/))
- Pre-treating normal human keratinocytes with an Opuntia ficus-indica cladode water extract protected against UVA-induced oxidative stress and apoptosis by inhibiting free radicals, lipid peroxidation, and GSH depletion. ([Bioorganic & Medicinal Chemistry Letters, 2017](https://pubmed.ncbi.nlm.nih.gov/29107540/))

## Why other products fit combination skin better

- Chemical peels with 30% supramolecular salicylic acid effectively treated acne and reduced facial sebum secretion while improving skin hydration and barrier function in 25 patients. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35073439/))
- Daily treatment with a facial serum containing multiple acids reduced post-inflammatory hyperchromia lesion grade and number by 29.4% at 56 days, and decreased skin oiliness by 30.7% at 7 days in Brazilian patients with acne vulgaris. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33617668/))

## What reviewers say

Based on limited data, users consistently describe this cleanser as an exceptionally gentle powder-to-foam exfoliant that effectively smooths skin texture without stripping moisture. It is frequently recommended for sensitive, acne-prone, and oily skin types, with many users reporting a reduction in small bumps and a baby-soft finish after use.

- Liked: Gentle exfoliation (mostly mentioned)
- Liked: Skin texture improvement (often mentioned)
- Liked: Deep cleansing (sometimes noted)
- Liked: Non-stripping (sometimes noted)
- Disliked: Packaging design (sometimes noted)
- Disliked: Clumping issues (rarely noted)
- Disliked: Messy application (rarely noted)
- Disliked: Price vs. quantity (rarely noted)

## How to apply

- Could be used as part of your PM routine once a week. Start 3x/week and build up to daily use if your skin tolerates it well.
- Apply the enzyme powder cleanser after your regular cleanser and toner, but before your moisturizer.
- Pour a small amount into wet hands and rub together to create a creamy foam, then massage gently onto the face.
- Apply the enzyme powder cleanser on slightly damp skin to help activate the gentle exfoliating enzymes.
- Avoid the eye area and do a patch test before your first use to ensure your skin feels comfortable.
- Video: https://storage.pora.ai/2d8db6e67371d665a6a7736b5ed5d762.mp4

## Questions and answers

### How well does CELL BY CELL Soft Enzyme Powder work for combination skin?

CELL BY CELL Soft Enzyme Powder works moderately well for combination skin because it removes impurities safely without irritation, but a cleanser of this type needs specialized ingredients to effectively manage oily shine and keep the skin balanced.
Sources: [Journal of Cosmetic Science, 2007](https://pubmed.ncbi.nlm.nih.gov/17598025/)

### Which ingredients make this cleanser a good fit for combination skin?

Sodium Cocoyl Isethionate and Sodium Lauroyl Glutamate make this cleanser a good fit because they gently remove dirt without causing irritation. Aloe Barbadensis Leaf Juice and Sorbitol also help by bringing moisture to the skin. To work best for combination skin, a cleanser of this type needs ingredients that effectively manage oily shine and provide gentle exfoliation.
Sources: [Journal of Cosmetic Science, 2013](https://pubmed.ncbi.nlm.nih.gov/23752031/)

### What does Sodium Cocoyl Isethionate do for combination skin?

Sodium cocoyl isethionate helps clean combination skin gently without drying out the dry parts or stripping natural moisture. Its large cleansing structures are too big to sink into the skin barrier, which keeps your face feeling soft and comfortable instead of tight.
Sources: [Journal of Cosmetic Science, 2007](https://pubmed.ncbi.nlm.nih.gov/17598025/), [Molecules, 2022](https://pubmed.ncbi.nlm.nih.gov/35335373/)

### What does Aloe Vera Leaf Juice do for combination skin?

Aloe vera leaf juice helps keep combination skin hydrated by increasing water content without making it oily. It also helps calm redness and supports skin recovery.
Sources: [Skin Research and Technology, 2006](https://pubmed.ncbi.nlm.nih.gov/17026654/), [Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/)

### Where does it go in a skincare routine for combination skin?

This enzyme powder is used as a weekly step in a combination skin routine, after your makeup remover and cleanser. While it safely cleanses without irritation, it lacks specialized ingredients to effectively manage oily shine, which combination skin requires for a better fit.

### Can I use it with retinol, and in what order?

You can use this powder cleanser alongside retinol, but apply them at different times or days since the powder acts as an exfoliант that may make your skin sensitive if layered directly with strong active ingredients. Use this gentle cleanser on your weekly routine days to wash your face before applying your treatments and moisturizers.

### How often should I use this cleanser?

This enzyme powder is used once a week as part of your routine. Combination skin needs products that help manage oily shine and balance oil production.

### Can it clog pores, cause breakouts or purging for combination skin?

It is unlikely to clog pores or cause breakouts on combination skin because its gentle cleansers wash away impurities without irritating the skin barrier. However, because it lacks specialized ingredients to manage oily shine, combination skin needs added ingredients that balance oil production and keep pores clear.
Sources: [Journal of Cosmetic Science, 2007](https://pubmed.ncbi.nlm.nih.gov/17598025/)

### Is it fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for combination skin

- [Dr. Barbara Sturm Enzyme Cleanser](https://lovi.care/skincare/au/p/dr-barbara-sturm/enzyme-cleanser/for/combination-skin) — High fit — A$114.68 at Amazon
- [Fancl Deep Clear Washing Powder](https://lovi.care/skincare/au/p/fancl/deep-clear-washing-powder/for/combination-skin) — High fit — A$30.00 at Amazon
- [Tatcha The Rice Polish: Deep](https://lovi.care/skincare/au/p/tatcha/the-rice-polish-deep/for/combination-skin) — High fit — A$113.00 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/au/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — A$73.61 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/au/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — A$42.00 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/au/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — A$22.99 at Amazon

## Where to buy

No store in Australia has a checked price for this product, so the page shows none.

## Ingredients

Zea Mays Starch, Sodium Cocoyl Isethionate, Sodium Lauroyl Glutamate, Aloe Barbadensis Leaf Juice, Opuntia Ficus-Indica Stem Extract, Allantoin, Collagen, Sorbitol, Ascorbyl Palmitate, Isopropyl Palmitate, Grapefruit Seed Extract, Pollen Extract, Titanium Dioxide, Citric Acid, Disodium Edta
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/cell-by-cell/soft-enzyme-powder/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/cell-by-cell/soft-enzyme-powder/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/cell-by-cell/soft-enzyme-powder/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/cell-by-cell/soft-enzyme-powder/for/combination-skin
- France: https://lovi.care/skincare/fr/p/cell-by-cell/soft-enzyme-powder/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/cell-by-cell/soft-enzyme-powder/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/cell-by-cell/soft-enzyme-powder/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/cell-by-cell/soft-enzyme-powder/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/cell-by-cell/soft-enzyme-powder/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/cell-by-cell/soft-enzyme-powder/for/combination-skin (this page)
- Singapore: https://lovi.care/skincare/sg/p/cell-by-cell/soft-enzyme-powder/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/cell-by-cell/soft-enzyme-powder/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/cell-by-cell/soft-enzyme-powder/for/combination-skin