# Avène Cicalfate Repair Cream for acne-prone skin

**Lovi Fit: High fit for acne-prone skin.**
Combination Skin Fit: Average · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/au/p/avene/cicalfate-repair-cream/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Australia.

Brand: [Avène](https://lovi.care/skincare/au/brands/avene)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/au/best/moisturizers)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for acne-prone skin; a few moisturizers fit it even better.

## Why this fit

- Offers moderate benefits for your acne, blemishes, and breakouts due to the presence of zinc oxide and copper sulfate which have anti-inflammatory and antimicrobial properties.
- It provides excellent moisturizing and skin repair, enhancing barrier resilience and promoting healing, though it lacks sufficient ingredients for optimal oil control on oily areas of your combination skin.
- The safety profile is excellent, with no risks of irritation for your acne-prone skin due to the absence of prohibited or harsh ingredients and the presence of soothing ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/au/p/avene/cicalfate-repair-cream/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/au/p/avene/cicalfate-repair-cream/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/au/p/avene/cicalfate-repair-cream/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/au/p/avene/cicalfate-repair-cream/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/au/p/avene/cicalfate-repair-cream/for/acne-prone-skin): High (this page)
- [Skin with dark spots](https://lovi.care/skincare/au/p/avene/cicalfate-repair-cream/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/au/p/avene/cicalfate-repair-cream/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/au/p/avene/cicalfate-repair-cream/for/dry-sensitive-skin): Superior
- [Oily acne-prone skin](https://lovi.care/skincare/au/p/avene/cicalfate-repair-cream/for/oily-acne-prone-skin): Average

## Key ingredients

Zinc Oxide, Glycerin, Beeswax, Copper Sulfate, Caprylic Capric Triglyceride

## What the research says

- Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles selectively inhibited C. acnes, outperformed erythromycin in preclinical acne models, and safely reduced acne lesions and redness in a clinical trial. ([Journal of Controlled Release, 2025](https://pubmed.ncbi.nlm.nih.gov/40254135/))
- Topical 0.5% hyaluronic-ZnO nanogel applied twice daily reduced inflammatory-lesion counts by 58% at week four in human subjects compared to baseline without causing erythema. ([Biomedicines, 2025](https://pubmed.ncbi.nlm.nih.gov/41007718/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical application of an emollient emulsion containing 15.0% caprylic/capric triglyceride doubled the amount of urocanic acid isomers and increased skin hydration with reduced transepidermal water loss in healthy subjects, though it did not prevent ultraviolet-induced urocanic acid isomerization. ([Life, 2023](https://pubmed.ncbi.nlm.nih.gov/37109405/))
- Nels cream achieved a similar reduction in inflammatory and noninflammatory lesion counts compared to 5% benzoyl peroxide in acne vulgaris patients, but caused significantly fewer side-effects such as peeling and dryness. ([Clinical and Experimental Dermatology, 2000](https://pubmed.ncbi.nlm.nih.gov/10671963/))
- Topically applied coated and uncoated zinc oxide nanoparticles under flexing and massage are retained in the stratum corneum with no significant penetration into the viable epidermis and no cellular toxicity in human skin. ([Nanomedicine, 2016](https://pubmed.ncbi.nlm.nih.gov/27102240/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Topical application of a honey, olive oil, and beeswax mixture three times daily for up to 4 weeks resulted in clinical responses in 86% of patients with pityriasis versicolor, 78% with tinea cruris, and 75% with tinea corporis. ([Complementary Therapies in Medicine, 2004](https://pubmed.ncbi.nlm.nih.gov/15130571/))
- A prototype body cream containing bee venom, propolis, honey, beeswax, and royal jelly demonstrated stability for 90 days, high antioxidant capacity of 85.45%, lack of cytotoxicity with over 70% cell viability, and no irritation or allergic reaction in dermatological analysis, while improving skin parameters in a panel test. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35238152/))
- MUD1 protected human dermal fibroblasts against AAPH-induced oxidative stress by increasing cell viability, reducing oxidative damage, improving mitochondrial functionality, and enhancing wound healing capacities. ([International Journal of Molecular Sciences, 2018](https://pubmed.ncbi.nlm.nih.gov/30235888/))
- A single application of a topical formulation containing copper sulfate pentahydrate and Hypericum perforatum effectively managed HSV-1 and HSV-2 lesions with lower odds of burning, stinging, acute pain, erythema, and vesiculation compared to topical 5% Acyclovir cream in adult patients. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22270204/))

## What reviewers say

Users frequently report that the product separates into oil and water, and some find its texture too heavy or greasy for acne-prone skin.

- Liked: Restores skin barrier (mostly mentioned)
- Disliked: Product separation (mostly mentioned)
- Liked: Rich and protective (often mentioned)
- Liked: Soothing and calming (often mentioned)
- Liked: Gentle formula (sometimes noted)
- Liked: Versatile healing (sometimes noted)
- Disliked: Greasy texture (sometimes noted)
- Disliked: Acne breakouts (rarely noted)
- Disliked: Packaging issues (rarely noted)
- Disliked: White cast (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help keep breakouts under control.
- Apply after your cleanser and toner, and make sure to use your SPF right after in the morning.
- Gently spread a small amount of moisturizer over your face using soft motions. Let it absorb into the skin for a minute before getting dressed or applying makeup.
- Apply on slightly damp skin to help lock in extra moisture. This keeps your combination skin balanced without feeling heavy.
- Avoid the eye area and do a patch test before your first use. Stop using if you feel any irritation.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes Avène Cicalfate Cream a great fit for acne-prone skin?

Avène Cicalfate Repair Cream is a great fit for acne-prone skin because zinc oxide and copper sulfate help calm breakouts and blemishes while keeping the skin safe from irritation. It also provides deep moisturizing and repair to help your skin heal.
Sources: [Journal of Controlled Release, 2025](https://pubmed.ncbi.nlm.nih.gov/40254135/), [Biomedicines, 2025](https://pubmed.ncbi.nlm.nih.gov/41007718/)

### Which ingredients make this cream a good fit for acne-prone skin?

Zinc oxide and copper sulfate make this cream a great fit for your acne-prone skin because they help calm redness and fight blemishes. It is unlikely to cause irritation while keeping your skin soft and healed.
Sources: [Journal of Controlled Release, 2025](https://pubmed.ncbi.nlm.nih.gov/40254135/), [Biomedicines, 2025](https://pubmed.ncbi.nlm.nih.gov/41007718/)

### What does Zinc Oxide do for acne-prone skin?

Zinc oxide helps calm acne-prone skin by reducing breakouts, redness, and the bacteria linked to pimples. Studies show that using it on your skin is generally safe and unlikely to cause irritation.
Sources: [Journal of Controlled Release, 2025](https://pubmed.ncbi.nlm.nih.gov/40254135/), [Biomedicines, 2025](https://pubmed.ncbi.nlm.nih.gov/41007718/)

### What does Glycerin do for acne-prone skin?

Glycerin helps keep acne-prone skin hydrated and calm without clogging pores or feeling heavy. It supports the skin barrier so it stays soft and smooth while handling everyday treatments.
Sources: [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/), [International Journal of Toxicology, 2019](https://pubmed.ncbi.nlm.nih.gov/31840548/)

### Where does this cream go in a skincare routine for acne-prone skin?

This cream goes in your evening routine as a treatment step after cleansing and toning, followed by your moisturizer. It is unlikely to cause irritation for acne-prone skin and helps soothe blemishes while supporting skin repair.
Sources: [Journal of Controlled Release, 2025](https://pubmed.ncbi.nlm.nih.gov/40254135/), [Biomedicines, 2025](https://pubmed.ncbi.nlm.nih.gov/41007718/)

### Can I use this cream with retinol, and in what order?

You can use this cream alongside retinol by applying the treatment first and following it with your moisturizer in the evening routine. Using a barrier-enhancing moisturizer helps reduce irritation and dryness while supporting skin recovery during active treatments.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [The Journal of Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/24930436/)

### How often should I use this cream?

You can use this cream daily as a moisturizing treatment to help soothe acne-prone skin and support your skin barrier. Regular daily applications are unlikely to cause irritation and help keep skin calm and hydrated.
Sources: [Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/14571069/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can this cream clog pores, cause breakouts or purging for acne-prone skin?

Avène Cicalfate Repair Cream is a great fit because it helps calm breakouts with zinc oxide and copper sulfate while keeping irritation very unlikely. Reviewers rarely report acne breakouts from it, though it can feel greasy for some.
Sources: [Journal of Controlled Release, 2025](https://pubmed.ncbi.nlm.nih.gov/40254135/), [Biomedicines, 2025](https://pubmed.ncbi.nlm.nih.gov/41007718/)

### Can I use this cream around the eyes or on my body?

Avène Cicalfate Repair Cream is well suited for the thin skin around the eyes and various body areas because it has a very safe formula with soothing ingredients and no harsh irritants. It is unlikely to cause irritation while providing deep moisture and repair to delicate or dry areas.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for acne-prone skin

- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/au/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/acne-prone-skin) — Superior fit — A$24.00 at Amazon
- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/au/p/cosrx/advanced-snail-96-mucin-power-essence/for/acne-prone-skin) — Superior fit — A$18.90 at Amazon
- [belif The True Cream Aqua Bomb](https://lovi.care/skincare/au/p/belif/the-true-cream-aqua-bomb/for/acne-prone-skin) — High fit — A$50.56 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/au/p/cerave/foaming-facial-cleanser/for/acne-prone-skin) — Superior fit — A$13.99 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/au/p/some-by-mi/snail-truecica-miracle-repair-toner/for/acne-prone-skin) — Superior fit — A$34.66 at Amazon
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/au/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/acne-prone-skin) — Superior fit — A$80.43 at Amazon

## Where to buy

- Amazon.com.au: A$24.99 (https://www.amazon.com.au/dp/B07YBCJBG2?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, Caprylic Capric Triglyceride, Mineral Oil, Glycerin, Hydrogenated Oil, Zinc Oxide, Propylene Glycol, Polyglyceryl-2 Sesquiisostearate, Peg-22 Dodecyl Glycol Copolymer, Aluminum Stearate, Aquaphilus Dolomiae Ferment Filtrate, Arginine, Beeswax, Copper Sulfate, Magnesium Stearate, Microcrystalline Wax, Tromethamine, Zinc Sulfate
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/avene/cicalfate-repair-cream/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/avene/cicalfate-repair-cream/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/avene/cicalfate-repair-cream/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/avene/cicalfate-repair-cream/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/avene/cicalfate-repair-cream/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/avene/cicalfate-repair-cream/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/avene/cicalfate-repair-cream/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/avene/cicalfate-repair-cream/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/avene/cicalfate-repair-cream/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/avene/cicalfate-repair-cream/for/acne-prone-skin (this page)
- Singapore: https://lovi.care/skincare/sg/p/avene/cicalfate-repair-cream/for/acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/avene/cicalfate-repair-cream/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/avene/cicalfate-repair-cream/for/acne-prone-skin