# Zinc sulfate and hexapeptide-9

Page: https://lovi.care/skincare/au/ingredients/zinc-sulfate-and-hexapeptide-9

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Australia.

Keep them apart

Use them at different times of day, applying the [zinc](https://lovi.care/skincare/au/ingredients/zinc) first, because mixing them together makes the peptide lose its effect. Zinc blocks the peptide from working properly on the skin, reducing the overall anti-aging results. The shopper can separate them by using one in the morning and the other at night.

- [All about zinc sulfate](https://lovi.care/skincare/au/ingredients/zinc-sulfate)
- [All about hexapeptide-9](https://lovi.care/skincare/au/ingredients/hexapeptide-9)

### [Zinc sulfate](https://lovi.care/skincare/au/ingredients/zinc-sulfate) products

- [Bioderma Sébium Gel moussant](https://lovi.care/skincare/au/p/bioderma/sebium-gel-moussant/for/oily-skin) — High fit — [A$18.69 at Amazon](https://www.amazon.com.au/dp/B000TUNMW4?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
- [Vichy Normaderm Phytosolution](https://lovi.care/skincare/au/p/vichy/normaderm-phytosolution/for/oily-skin) — High fit — [A$45.48 at Amazon](https://www.amazon.com.au/dp/B08888BXFJ?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)

### [Hexapeptide-9](https://lovi.care/skincare/au/ingredients/hexapeptide-9) products

- [Elemis Pro-Collagen Night Cream](https://lovi.care/skincare/au/p/elemis/pro-collagen-night-cream/for/dry-sensitive-skin) — Superior fit
- [Murad Cellular Hydration Repair Serum](https://lovi.care/skincare/au/p/murad/cellular-hydration-repair-serum/for/acne-prone-skin) — High fit
- [MARY & MAY 6 Peptide Complex Serum](https://lovi.care/skincare/au/p/mary-and-may/6-peptide-complex-serum/for/mature-skin) — High fit

## Questions and answers

### Can you use zinc sulfate and hexapeptide-9 together?

No, you should keep [zinc sulfate](https://lovi.care/skincare/au/ingredients/zinc-sulfate) and [hexapeptide-9](https://lovi.care/skincare/au/ingredients/hexapeptide-9) apart in your skincare routine. Zinc sulfate is an unchelated metal ion that may [complex](https://lovi.care/skincare/au/ingredients/complex) with peptides and reduce their biological activity.

### Which goes first, zinc sulfate or hexapeptide-9?

Keep zinc sulfate and hexapeptide-9 apart in your routine, as combining them may reduce their biological activity. Use them at separate times of day if you choose to use both.

### Are zinc sulfate and hexapeptide-9 good for sensitive skin?

Zinc sulfate and hexapeptide-9 should be kept apart in your routine because unchelated metal ions may complex with peptides and reduce their biological activity.

## Research on zinc sulfate and hexapeptide-9

- [Novel Cyclized Hexapeptide-9 Outperforms Retinol Against Skin Aging: A Randomized, Double-Blinded, Active- and Vehicle-Controlled Clinical Trial](https://pubmed.ncbi.nlm.nih.gov/40586182/) Hexapeptide-9 · Journal of Cosmetic Dermatology, 2025

## Other combinations

- Keep them apart: [Adapalene and hexapeptide-9](https://lovi.care/skincare/au/ingredients/adapalene-and-hexapeptide-9)
- Keep them apart: [Granactive retinoid and hexapeptide-9](https://lovi.care/skincare/au/ingredients/granactive-retinoid-and-hexapeptide-9)
- Keep them apart: [Hydroxypinacolone retinoate and hexapeptide-9](https://lovi.care/skincare/au/ingredients/hydroxypinacolone-retinoate-and-hexapeptide-9)
- Keep them apart: [Pro-retinol and hexapeptide-9](https://lovi.care/skincare/au/ingredients/pro-retinol-and-hexapeptide-9)
- Keep them apart: [Retinal and hexapeptide-9](https://lovi.care/skincare/au/ingredients/retinal-and-hexapeptide-9)
- Keep them apart: [Retinoid blend and hexapeptide-9](https://lovi.care/skincare/au/ingredients/retinoid-blend-and-hexapeptide-9)
- Depends on the strength: [Retinol and hexapeptide-9](https://lovi.care/skincare/au/ingredients/retinol-and-hexapeptide-9)
- Keep them apart: [Tretinoin and hexapeptide-9](https://lovi.care/skincare/au/ingredients/tretinoin-and-hexapeptide-9)
- Keep them apart: [Vitamin A and hexapeptide-9](https://lovi.care/skincare/au/ingredients/vitamin-a-and-hexapeptide-9)
- Work well together: [Liposome and hexapeptide-9](https://lovi.care/skincare/au/ingredients/liposome-and-hexapeptide-9)
- Work well together: [Microcapsule and hexapeptide-9](https://lovi.care/skincare/au/ingredients/microcapsule-and-hexapeptide-9)
- Depends on the strength: [Vitamin C and hexapeptide-9](https://lovi.care/skincare/au/ingredients/vitamin-c-and-hexapeptide-9)
- Work well together: [Betaine and hexapeptide-9](https://lovi.care/skincare/au/ingredients/betaine-and-hexapeptide-9)
- Work well together: [Glycerin and hexapeptide-9](https://lovi.care/skincare/au/ingredients/glycerin-and-hexapeptide-9)
- Work well together: [Hyaluronic acid and hexapeptide-9](https://lovi.care/skincare/au/ingredients/hyaluronic-acid-and-hexapeptide-9)
- Work well together: [Salicylic acid and zinc sulfate](https://lovi.care/skincare/au/ingredients/salicylic-acid-and-zinc-sulfate)
- Depends on the strength: [Niacinamide and hexapeptide-9](https://lovi.care/skincare/au/ingredients/niacinamide-and-hexapeptide-9)
- Work well together: [Panthenol and hexapeptide-9](https://lovi.care/skincare/au/ingredients/panthenol-and-hexapeptide-9)
- Work well together: [Bakuchiol and hexapeptide-9](https://lovi.care/skincare/au/ingredients/bakuchiol-and-hexapeptide-9)
- Work well together: [Arginine and hexapeptide-9](https://lovi.care/skincare/au/ingredients/arginine-and-hexapeptide-9)
- Work well together: [Hexapeptide-9 and GABA](https://lovi.care/skincare/au/ingredients/hexapeptide-9-and-gaba)
- Work well together: [Silk amino acids and hexapeptide-9](https://lovi.care/skincare/au/ingredients/silk-amino-acids-and-hexapeptide-9)
- Work well together: [Taurine and hexapeptide-9](https://lovi.care/skincare/au/ingredients/taurine-and-hexapeptide-9)
- Work well together: [Hexapeptide-9 and theanine](https://lovi.care/skincare/au/ingredients/hexapeptide-9-and-theanine)
- Keep them apart: [AHA blend glycolic and citric acids and hexapeptide-9](https://lovi.care/skincare/au/ingredients/aha-blend-glycolic-and-citric-acids-and-hexapeptide-9)
- Keep them apart: [Citric acid and hexapeptide-9](https://lovi.care/skincare/au/ingredients/citric-acid-and-hexapeptide-9)
- Keep them apart: [Glycolic acid and hexapeptide-9](https://lovi.care/skincare/au/ingredients/glycolic-acid-and-hexapeptide-9)
- Keep them apart: [Lactic acid and hexapeptide-9](https://lovi.care/skincare/au/ingredients/lactic-acid-and-hexapeptide-9)
- Keep them apart: [Mandelic acid and hexapeptide-9](https://lovi.care/skincare/au/ingredients/mandelic-acid-and-hexapeptide-9)
- Work well together: [Coenzyme Q10 and hexapeptide-9](https://lovi.care/skincare/au/ingredients/coenzyme-q10-and-hexapeptide-9)
- Work well together: [Green tea and hexapeptide-9](https://lovi.care/skincare/au/ingredients/green-tea-and-hexapeptide-9)
- Work well together: [Vitamin E and hexapeptide-9](https://lovi.care/skincare/au/ingredients/vitamin-e-and-hexapeptide-9)
- Work well together: [Hexapeptide-9 and beta-sitosterol](https://lovi.care/skincare/au/ingredients/hexapeptide-9-and-beta-sitosterol)
- Work well together: [Ceramide-building complex and hexapeptide-9](https://lovi.care/skincare/au/ingredients/ceramide-building-complex-and-hexapeptide-9)
- Work well together: [Cholesterol and hexapeptide-9](https://lovi.care/skincare/au/ingredients/cholesterol-and-hexapeptide-9)
- Work well together: [Phytosphingosine and hexapeptide-9](https://lovi.care/skincare/au/ingredients/phytosphingosine-and-hexapeptide-9)
- Work well together: [Phytosterol and hexapeptide-9](https://lovi.care/skincare/au/ingredients/phytosterol-and-hexapeptide-9)
- Work well together: [Hexapeptide-9 and squalene](https://lovi.care/skincare/au/ingredients/hexapeptide-9-and-squalene)
- Work well together: [Hexapeptide-9 and tri-ceramide complex](https://lovi.care/skincare/au/ingredients/hexapeptide-9-and-tri-ceramide-complex)
- Keep them apart: [Salicylic acid and hexapeptide-9](https://lovi.care/skincare/au/ingredients/salicylic-acid-and-hexapeptide-9)
- Keep them apart: [Hexapeptide-9 and baking soda](https://lovi.care/skincare/au/ingredients/hexapeptide-9-and-baking-soda)
- Keep them apart: [Bleach and hexapeptide-9](https://lovi.care/skincare/au/ingredients/bleach-and-hexapeptide-9)
- Keep them apart: [Potassium hydroxide and hexapeptide-9](https://lovi.care/skincare/au/ingredients/potassium-hydroxide-and-hexapeptide-9)
- Keep them apart: [Hexapeptide-9 and behenyl alcohol](https://lovi.care/skincare/au/ingredients/hexapeptide-9-and-behenyl-alcohol)
- Keep them apart: [Hexapeptide-9 and isopropyl alcohol](https://lovi.care/skincare/au/ingredients/hexapeptide-9-and-isopropyl-alcohol)
- Keep them apart: [Polyvinyl alcohol and hexapeptide-9](https://lovi.care/skincare/au/ingredients/polyvinyl-alcohol-and-hexapeptide-9)
- Work well together: [Niacinamide and zinc sulfate](https://lovi.care/skincare/au/ingredients/niacinamide-and-zinc-sulfate)
- Keep them apart: [Copper and hexapeptide-9](https://lovi.care/skincare/au/ingredients/copper-and-hexapeptide-9)
- Keep them apart: [Benzoyl peroxide and hexapeptide-9](https://lovi.care/skincare/au/ingredients/benzoyl-peroxide-and-hexapeptide-9)
- Keep them apart: [Acetyl hexapeptide-3 and zinc sulfate](https://lovi.care/skincare/au/ingredients/acetyl-hexapeptide-3-and-zinc-sulfate)
- Keep them apart: [Bio-placenta peptides and zinc sulfate](https://lovi.care/skincare/au/ingredients/bio-placenta-peptides-and-zinc-sulfate)
- Keep them apart: [Zinc sulfate and collagen peptide](https://lovi.care/skincare/au/ingredients/zinc-sulfate-and-collagen-peptide)
- Keep them apart: [Zinc sulfate and copper peptide](https://lovi.care/skincare/au/ingredients/zinc-sulfate-and-copper-peptide)
- Keep them apart: [Hexapeptide and zinc sulfate](https://lovi.care/skincare/au/ingredients/hexapeptide-and-zinc-sulfate)
- Keep them apart: [Magnesium and hexapeptide-9](https://lovi.care/skincare/au/ingredients/magnesium-and-hexapeptide-9)
- Keep them apart: [Zinc and hexapeptide-9](https://lovi.care/skincare/au/ingredients/zinc-and-hexapeptide-9)
- Keep them apart: [Zinc sulfate and palmitoyl pentapeptide-4](https://lovi.care/skincare/au/ingredients/zinc-sulfate-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Zinc sulfate and palmitoyl tripeptide-1](https://lovi.care/skincare/au/ingredients/zinc-sulfate-and-palmitoyl-tripeptide-1)
- Keep them apart: [Zinc sulfate and peptide-rich plasma](https://lovi.care/skincare/au/ingredients/zinc-sulfate-and-peptide-rich-plasma)
- Keep them apart: [Zinc sulfate and triple peptide blend](https://lovi.care/skincare/au/ingredients/zinc-sulfate-and-triple-peptide-blend)
- Work well together: [Benzoyl peroxide and zinc sulfate](https://lovi.care/skincare/au/ingredients/benzoyl-peroxide-and-zinc-sulfate)
- Keep them apart: [Azelaic acid and hexapeptide-9](https://lovi.care/skincare/au/ingredients/azelaic-acid-and-hexapeptide-9)
- Keep them apart: [Hexapeptide-9 and protease](https://lovi.care/skincare/au/ingredients/hexapeptide-9-and-protease)
- Keep them apart: [Superoxide dismutase and hexapeptide-9](https://lovi.care/skincare/au/ingredients/superoxide-dismutase-and-hexapeptide-9)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi checks every pairing with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this pairing advice: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/ingredients/zinc-sulfate-and-hexapeptide-9
- United Kingdom: https://lovi.care/skincare/uk/ingredients/zinc-sulfate-and-hexapeptide-9
- Ireland: https://lovi.care/skincare/ie/ingredients/zinc-sulfate-and-hexapeptide-9
- Germany: https://lovi.care/skincare/de/ingredients/zinc-sulfate-and-hexapeptide-9
- France: https://lovi.care/skincare/fr/ingredients/zinc-sulfate-and-hexapeptide-9
- Italy: https://lovi.care/skincare/it/ingredients/zinc-sulfate-and-hexapeptide-9
- Netherlands: https://lovi.care/skincare/nl/ingredients/zinc-sulfate-and-hexapeptide-9
- Spain: https://lovi.care/skincare/es/ingredients/zinc-sulfate-and-hexapeptide-9
- Canada: https://lovi.care/skincare/ca/ingredients/zinc-sulfate-and-hexapeptide-9
- Australia: https://lovi.care/skincare/au/ingredients/zinc-sulfate-and-hexapeptide-9 (this page)
- Singapore: https://lovi.care/skincare/sg/ingredients/zinc-sulfate-and-hexapeptide-9
- Saudi Arabia: https://lovi.care/skincare/sa/ingredients/zinc-sulfate-and-hexapeptide-9
- United Arab Emirates: https://lovi.care/skincare/ae/ingredients/zinc-sulfate-and-hexapeptide-9