# Squalene

Page: https://lovi.care/skincare/au/ingredients/squalene

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Australia.

Squalene deeply softens the skin, fights daily damage, boosts moisture, and supports healthy tissue based on research models, while also visibly increasing skin thickness, [collagen](https://lovi.care/skincare/au/ingredients/collagen), and plumping compounds when paired with [vitamin C](https://lovi.care/skincare/au/ingredients/vitamin-c). This gentle oil suits most skin types and is easily found in lightweight [serums](https://lovi.care/skincare/au/ingredients/serum). It fits smoothly into your daily routine, working especially well alongside [bio-placenta peptides](https://lovi.care/skincare/au/ingredients/bio-placenta-peptides), [hexapeptide](https://lovi.care/skincare/au/ingredients/hexapeptide), and [acetyl hexapeptide-3](https://lovi.care/skincare/au/ingredients/acetyl-hexapeptide-3).

[Molecules, 2009](https://pubmed.ncbi.nlm.nih.gov/19169201/) [Scientific Reports, 2020](https://pubmed.ncbi.nlm.nih.gov/33037252/)

This page shows squalene products with a Lovi page. For every product, and a routine built for your skin, use the Lovi app.

### Popular squalene products

- [Clinique Even Better Clinical Dark Spot Corrector](https://lovi.care/skincare/au/p/clinique/even-better-clinical-dark-spot-corrector/for/oily-skin) — High fit
- [Elizabeth Arden Advanced Ceramide Capsules Daily Youth Restoring Serum](https://lovi.care/skincare/au/p/elizabeth-arden/advanced-ceramide-capsules-daily-youth-restoring-serum/for/oily-skin) — High fit — [A$120.73 at Amazon](https://www.amazon.com.au/dp/B09B2Q1NZ7?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)

### Other squalene products

- [Clinique Even Better Clinical Dark Spot Corrector](https://lovi.care/skincare/au/p/clinique/even-better-clinical-dark-spot-corrector/for/oily-skin) — High fit
- [Aestura A-Cica 365 Blemish Calming Serum](https://lovi.care/skincare/au/p/aestura/a-cica-365-blemish-calming-serum/for/sensitive-skin) — High fit — [A$65.00 at Amazon](https://www.amazon.com.au/dp/B09Z6L7NRC?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
- [Elizabeth Arden Advanced Ceramide Capsules Daily Youth Restoring Serum](https://lovi.care/skincare/au/p/elizabeth-arden/advanced-ceramide-capsules-daily-youth-restoring-serum/for/oily-skin) — High fit — [A$120.73 at Amazon](https://www.amazon.com.au/dp/B09B2Q1NZ7?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
- [Perricone MD Vitamin C Ester CCC+ Ferulic Brightening Under-Eye Cream](https://lovi.care/skincare/au/p/perricone-md/vitamin-c-ester-ccc-ferulic-brightening-under-eye-cream/for/dark-spots) — High fit

## What to combine squalene with

Ingredient Together How to use them

[Bio-placenta peptides](https://lovi.care/skincare/au/ingredients/bio-placenta-peptides) Works well Use them together in the same routine, applying the squalene after your peptide product, because the squalene helps the peptides absorb better. [Squalene and bio-placenta peptides](https://lovi.care/skincare/au/ingredients/bio-placenta-peptides-and-squalene) [Hexapeptide](https://lovi.care/skincare/au/ingredients/hexapeptide) Works well Use them together by applying the peptide [serum](https://lovi.care/skincare/au/ingredients/serum) first, because the squalene oil helps it sink in and locks in moisture. [Squalene and hexapeptide](https://lovi.care/skincare/au/ingredients/hexapeptide-and-squalene) [Acetyl hexapeptide-3](https://lovi.care/skincare/au/ingredients/acetyl-hexapeptide-3) Works well Use them together in the same routine, applying the squalene after the peptide. [Squalene and acetyl hexapeptide-3](https://lovi.care/skincare/au/ingredients/acetyl-hexapeptide-3-and-squalene) [Collagen peptide](https://lovi.care/skincare/au/ingredients/collagen-peptide) Works well Use them together by applying the [collagen peptide](https://lovi.care/skincare/au/ingredients/collagen-peptide) first, because lipids help peptides sink in better. [Squalene and collagen peptide](https://lovi.care/skincare/au/ingredients/collagen-peptide-and-squalene) [Copper peptide](https://lovi.care/skincare/au/ingredients/copper-peptide) Works well Use them together in the same routine, applying the squalene after the [copper peptide](https://lovi.care/skincare/au/ingredients/copper-peptide). [Squalene and copper peptide](https://lovi.care/skincare/au/ingredients/copper-peptide-and-squalene) [Hexapeptide-9](https://lovi.care/skincare/au/ingredients/hexapeptide-9) Works well Use them together in the same routine, applying the squalene after the [hexapeptide-9](https://lovi.care/skincare/au/ingredients/hexapeptide-9), because the oil helps the peptide sink in better. [Squalene and hexapeptide-9](https://lovi.care/skincare/au/ingredients/hexapeptide-9-and-squalene) [Peptide-rich plasma](https://lovi.care/skincare/au/ingredients/peptide-rich-plasma) Works well Use them together in the same routine, applying the squalene after your peptide product. [Squalene and peptide-rich plasma](https://lovi.care/skincare/au/ingredients/peptide-rich-plasma-and-squalene) [Triple peptide blend](https://lovi.care/skincare/au/ingredients/triple-peptide-blend) Works well Use them together in the same routine, applying your peptide blend first and following with your squalane. [Squalene and triple peptide blend](https://lovi.care/skincare/au/ingredients/squalene-and-triple-peptide-blend) [Palmitoyl pentapeptide-4](https://lovi.care/skincare/au/ingredients/palmitoyl-pentapeptide-4) Works well Use them together in the same routine, applying the squalane after the peptide. [Squalene and palmitoyl pentapeptide-4](https://lovi.care/skincare/au/ingredients/squalene-and-palmitoyl-pentapeptide-4) [Palmitoyl tripeptide-1](https://lovi.care/skincare/au/ingredients/palmitoyl-tripeptide-1) Works well Use them together in the same routine, applying the peptide serum first and following with the squalane. [Squalene and palmitoyl tripeptide-1](https://lovi.care/skincare/au/ingredients/squalene-and-palmitoyl-tripeptide-1)

From the ingredient rules behind the "Works well with" and "Don't mix with" notes on every product in the Lovi app.

## Questions and answers

### What does squalene do for the skin?

Squalene acts as an emollient, antioxidant, hydrating agent, and antitumor substance for the skin based on scientific models.

[Molecules, 2009](https://pubmed.ncbi.nlm.nih.gov/19169201/)

### How do you use squalene?

Squalene acts as an emollient, antioxidant, hydrating agent, and antitumor substance based on studies. It helps the skin by providing these protective and moisturizing benefits.

[Molecules, 2009](https://pubmed.ncbi.nlm.nih.gov/19169201/)

### Should you use squalene in the morning or at night?

Squalene may be used both morning and night as a hydrating emollient and antioxidant.

[Molecules, 2009](https://pubmed.ncbi.nlm.nih.gov/19169201/)

### Can you use squalene every day?

Yes, you can use squalene every day because it acts as a gentle emollient and hydrating agent for the skin.

[Molecules, 2009](https://pubmed.ncbi.nlm.nih.gov/19169201/)

### Does squalene cause purging or irritation?

Squalene is unlikely to cause purging or irritation because it is a natural emollient that is well tolerated by the skin. It acts as a hydrating agent and antioxidant to support the skin barrier.

[Molecules, 2009](https://pubmed.ncbi.nlm.nih.gov/19169201/)

### Which skin types is squalene best for?

Squalene is best for dry skin as it acts as an emollient and hydrating agent.

[Molecules, 2009](https://pubmed.ncbi.nlm.nih.gov/19169201/)

### Can you use squalene with bio-placenta peptides?

Yes, you can use squalene with [bio-placenta peptides](https://lovi.care/skincare/au/ingredients/bio-placenta-peptides) in the same routine by applying the squalene after your peptide product, because the squalene helps the peptides absorb better.

## Research on squalene

- [Biological and pharmacological activities of squalene and related compounds: potential uses in cosmetic dermatology](https://pubmed.ncbi.nlm.nih.gov/19169201/) Squalene · Molecules, 2009
- [Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin](https://pubmed.ncbi.nlm.nih.gov/33037252/) Squalene · Scientific Reports, 2020

## Combining squalene

- Work well together: [Acetyl hexapeptide-3 and squalene](https://lovi.care/skincare/au/ingredients/acetyl-hexapeptide-3-and-squalene)
- Work well together: [Bio-placenta peptides and squalene](https://lovi.care/skincare/au/ingredients/bio-placenta-peptides-and-squalene)
- Work well together: [Collagen peptide and squalene](https://lovi.care/skincare/au/ingredients/collagen-peptide-and-squalene)
- Work well together: [Copper peptide and squalene](https://lovi.care/skincare/au/ingredients/copper-peptide-and-squalene)
- Work well together: [Hexapeptide and squalene](https://lovi.care/skincare/au/ingredients/hexapeptide-and-squalene)
- Work well together: [Hexapeptide-9 and squalene](https://lovi.care/skincare/au/ingredients/hexapeptide-9-and-squalene)
- Work well together: [Squalene and palmitoyl pentapeptide-4](https://lovi.care/skincare/au/ingredients/squalene-and-palmitoyl-pentapeptide-4)
- Work well together: [Squalene and palmitoyl tripeptide-1](https://lovi.care/skincare/au/ingredients/squalene-and-palmitoyl-tripeptide-1)
- Work well together: [Peptide-rich plasma and squalene](https://lovi.care/skincare/au/ingredients/peptide-rich-plasma-and-squalene)
- Work well together: [Squalene and triple peptide blend](https://lovi.care/skincare/au/ingredients/squalene-and-triple-peptide-blend)

## Brands with squalene

- American skincare: [Elizabeth Arden](https://lovi.care/skincare/au/brands/elizabeth-arden)
- American skincare: [Clinique](https://lovi.care/skincare/au/brands/clinique)
- American skincare: [Perricone MD](https://lovi.care/skincare/au/brands/perricone-md)
- Korean skincare: [Aestura](https://lovi.care/skincare/au/brands/aestura)

## Related ingredients

- [Bio-placenta peptides](https://lovi.care/skincare/au/ingredients/bio-placenta-peptides)
- [Hexapeptide](https://lovi.care/skincare/au/ingredients/hexapeptide)
- [Acetyl hexapeptide-3](https://lovi.care/skincare/au/ingredients/acetyl-hexapeptide-3)
- [Collagen peptide](https://lovi.care/skincare/au/ingredients/collagen-peptide)
- [Copper peptide](https://lovi.care/skincare/au/ingredients/copper-peptide)
- [Hexapeptide-9](https://lovi.care/skincare/au/ingredients/hexapeptide-9)
- [Peptide-rich plasma](https://lovi.care/skincare/au/ingredients/peptide-rich-plasma)
- [Triple peptide blend](https://lovi.care/skincare/au/ingredients/triple-peptide-blend)
- [Palmitoyl pentapeptide-4](https://lovi.care/skincare/au/ingredients/palmitoyl-pentapeptide-4)
- [Palmitoyl tripeptide-1](https://lovi.care/skincare/au/ingredients/palmitoyl-tripeptide-1)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi checks every ingredient with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this ingredient guide: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/ingredients/squalene
- United Kingdom: https://lovi.care/skincare/uk/ingredients/squalene
- Ireland: https://lovi.care/skincare/ie/ingredients/squalene
- Germany: https://lovi.care/skincare/de/ingredients/squalene
- France: https://lovi.care/skincare/fr/ingredients/squalene
- Italy: https://lovi.care/skincare/it/ingredients/squalene
- Netherlands: https://lovi.care/skincare/nl/ingredients/squalene
- Spain: https://lovi.care/skincare/es/ingredients/squalene
- Canada: https://lovi.care/skincare/ca/ingredients/squalene
- Australia: https://lovi.care/skincare/au/ingredients/squalene (this page)
- Singapore: https://lovi.care/skincare/sg/ingredients/squalene
- Saudi Arabia: https://lovi.care/skincare/sa/ingredients/squalene
- United Arab Emirates: https://lovi.care/skincare/ae/ingredients/squalene