# Phytosphingosine and triple peptide blend

Page: https://lovi.care/skincare/au/ingredients/phytosphingosine-and-triple-peptide-blend

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Australia.

Work well together

Use them together in the same routine, applying the peptide blend first and the [phytosphingosine](https://lovi.care/skincare/au/ingredients/phytosphingosine) right after to lock in moisture. Phytosphingosine helps your skin absorb the peptides better while strengthening your natural moisture barrier. If your skin feels sensitive, you can apply them on alternate nights or switch to a gentler product.

- [All about phytosphingosine](https://lovi.care/skincare/au/ingredients/phytosphingosine)
- [All about triple peptide blend](https://lovi.care/skincare/au/ingredients/triple-peptide-blend)

### [Phytosphingosine](https://lovi.care/skincare/au/ingredients/phytosphingosine) products

- [CeraVe Hydrating Facial Cleanser](https://lovi.care/skincare/au/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — [A$19.39 at Amazon](https://www.amazon.com.au/dp/B07C5XPXDC?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
- [CeraVe PM Facial Moisturizing Lotion](https://lovi.care/skincare/au/p/cerave/pm-facial-moisturizing-lotion/for/acne-prone-skin) — Superior fit — [A$36.14 at Amazon](https://www.amazon.com.au/dp/B00365DABC?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
- [Aestura Atobarrier 365 Cream](https://lovi.care/skincare/au/p/aestura/atobarrier-365-cream/for/dry-skin) — High fit — [A$43.95 at Amazon](https://www.amazon.com.au/dp/B09YDCCJBJ?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
- [Cetaphil Ceramide Serum](https://lovi.care/skincare/au/p/cetaphil/ceramide-serum/for/acne-prone-skin) — Superior fit — [A$36.72 at Amazon](https://www.amazon.com.au/dp/B0CZD72G5W?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
- [Bioderma Atoderm Intensive Eye](https://lovi.care/skincare/au/p/bioderma/atoderm-intensive-eye/for/acne-prone-skin) — High fit
- [Obagi Rebalance Skin Barrier Recovery Cream](https://lovi.care/skincare/au/p/obagi/rebalance-skin-barrier-recovery-cream/for/dry-sensitive-skin) — High fit
- [Elizabeth Arden Advanced Ceramide Capsules Daily Youth Restoring Serum](https://lovi.care/skincare/au/p/elizabeth-arden/advanced-ceramide-capsules-daily-youth-restoring-serum/for/oily-skin) — High fit — [A$120.73 at Amazon](https://www.amazon.com.au/dp/B09B2Q1NZ7?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)

### [Triple peptide blend](https://lovi.care/skincare/au/ingredients/triple-peptide-blend) products

- [Drunk Elephant A-Passioni Retinol Cream](https://lovi.care/skincare/au/p/drunk-elephant/a-passioni-retinol-cream/for/mature-skin) — High fit — [A$71.86 at Amazon](https://www.amazon.com.au/dp/B08TGGGZM5?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)

## Questions and answers

### Can you use phytosphingosine and triple peptide blend together?

Yes, [phytosphingosine](https://lovi.care/skincare/au/ingredients/phytosphingosine) and [triple peptide blend](https://lovi.care/skincare/au/ingredients/triple-peptide-blend) work well together to enhance skin barrier repair and support skin structure. Combining these ingredients helps improve absorption and reinforces the skin.

[Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/) [Journal of the European Academy of Dermatology and Venereology, 2002](https://pubmed.ncbi.nlm.nih.gov/12482041/)

### Which goes first, phytosphingosine or triple peptide blend?

Phytosphingosine and triple peptide blend work well together because combining them helps enhance skin barrier repair and support. Lovi rates this combination as Superior.

[Journal of the European Academy of Dermatology and Venereology, 2002](https://pubmed.ncbi.nlm.nih.gov/12482041/) [Journal of Cosmetic Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/20618556/)

### Are phytosphingosine and triple peptide blend good for sensitive skin?

Phytosphingosine and triple peptide blend work well together to help repair and support the skin barrier, making them beneficial for dry, mature, and barrier-impaired skin.

[Journal of the European Academy of Dermatology and Venereology, 2002](https://pubmed.ncbi.nlm.nih.gov/12482041/) [Journal of Cosmetic Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/20618556/)

## Research on phytosphingosine and triple peptide blend

- [Anti-microbial and -inflammatory activity and efficacy of phytosphingosine: an in vitro and in vivo study addressing acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/18489348/) Phytosphingosine · International Journal of Cosmetic Science, 2007
- [Anti-Wrinkle Benefits of Peptides Complex Stimulating Skin Basement Membrane Proteins Expression](https://pubmed.ncbi.nlm.nih.gov/31861912/) Triple peptide blend · International Journal of Molecular Sciences, 2019
- [Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications](https://pubmed.ncbi.nlm.nih.gov/25817264/) Triple peptide blend · Journal of Cosmetic Dermatology, 2015
- [Repair of acetone- and sodium lauryl sulphate-damaged human skin barrier function using topically applied emulsions containing barrier lipids](https://pubmed.ncbi.nlm.nih.gov/12482041/) Phytosphingosine · Journal of the European Academy of Dermatology and Venereology, 2002
- [Salicyloyl-phytosphingosine: a novel agent for the repair of photoaged skin](https://pubmed.ncbi.nlm.nih.gov/18489360/) Phytosphingosine · International Journal of Cosmetic Science, 2007
- [Synergistic action of a triple peptide complex on an essential extra-cellular matrix protein exhibits significant anti-aging benefits](https://pubmed.ncbi.nlm.nih.gov/20618556/) Triple peptide blend · Journal of Cosmetic Dermatology, 2010

## Other combinations

- Keep them apart: [Adapalene and triple peptide blend](https://lovi.care/skincare/au/ingredients/adapalene-and-triple-peptide-blend)
- Keep them apart: [Granactive retinoid and triple peptide blend](https://lovi.care/skincare/au/ingredients/granactive-retinoid-and-triple-peptide-blend)
- Keep them apart: [Hydroxypinacolone retinoate and triple peptide blend](https://lovi.care/skincare/au/ingredients/hydroxypinacolone-retinoate-and-triple-peptide-blend)
- Keep them apart: [Pro-retinol and triple peptide blend](https://lovi.care/skincare/au/ingredients/pro-retinol-and-triple-peptide-blend)
- Keep them apart: [Retinal and triple peptide blend](https://lovi.care/skincare/au/ingredients/retinal-and-triple-peptide-blend)
- Keep them apart: [Retinoid blend and triple peptide blend](https://lovi.care/skincare/au/ingredients/retinoid-blend-and-triple-peptide-blend)
- Depends on the strength: [Retinol and triple peptide blend](https://lovi.care/skincare/au/ingredients/retinol-and-triple-peptide-blend)
- Keep them apart: [Tretinoin and triple peptide blend](https://lovi.care/skincare/au/ingredients/tretinoin-and-triple-peptide-blend)
- Keep them apart: [Vitamin A and triple peptide blend](https://lovi.care/skincare/au/ingredients/vitamin-a-and-triple-peptide-blend)
- Work well together: [Liposome and triple peptide blend](https://lovi.care/skincare/au/ingredients/liposome-and-triple-peptide-blend)
- Work well together: [Microcapsule and triple peptide blend](https://lovi.care/skincare/au/ingredients/microcapsule-and-triple-peptide-blend)
- Keep them apart: [Vitamin C and triple peptide blend](https://lovi.care/skincare/au/ingredients/vitamin-c-and-triple-peptide-blend)
- Work well together: [Betaine and triple peptide blend](https://lovi.care/skincare/au/ingredients/betaine-and-triple-peptide-blend)
- Work well together: [Glycerin and triple peptide blend](https://lovi.care/skincare/au/ingredients/glycerin-and-triple-peptide-blend)
- Work well together: [Hyaluronic acid and triple peptide blend](https://lovi.care/skincare/au/ingredients/hyaluronic-acid-and-triple-peptide-blend)
- Depends on the strength: [Niacinamide and triple peptide blend](https://lovi.care/skincare/au/ingredients/niacinamide-and-triple-peptide-blend)
- Work well together: [Panthenol and triple peptide blend](https://lovi.care/skincare/au/ingredients/panthenol-and-triple-peptide-blend)
- Work well together: [Bakuchiol and triple peptide blend](https://lovi.care/skincare/au/ingredients/bakuchiol-and-triple-peptide-blend)
- Work well together: [Arginine and triple peptide blend](https://lovi.care/skincare/au/ingredients/arginine-and-triple-peptide-blend)
- Work well together: [Triple peptide blend and GABA](https://lovi.care/skincare/au/ingredients/triple-peptide-blend-and-gaba)
- Work well together: [Silk amino acids and triple peptide blend](https://lovi.care/skincare/au/ingredients/silk-amino-acids-and-triple-peptide-blend)
- Work well together: [Taurine and triple peptide blend](https://lovi.care/skincare/au/ingredients/taurine-and-triple-peptide-blend)
- Work well together: [Triple peptide blend and theanine](https://lovi.care/skincare/au/ingredients/triple-peptide-blend-and-theanine)
- Keep them apart: [AHA blend glycolic and citric acids and triple peptide blend](https://lovi.care/skincare/au/ingredients/aha-blend-glycolic-and-citric-acids-and-triple-peptide-blend)
- Keep them apart: [Citric acid and triple peptide blend](https://lovi.care/skincare/au/ingredients/citric-acid-and-triple-peptide-blend)
- Keep them apart: [Glycolic acid and triple peptide blend](https://lovi.care/skincare/au/ingredients/glycolic-acid-and-triple-peptide-blend)
- Keep them apart: [Lactic acid and triple peptide blend](https://lovi.care/skincare/au/ingredients/lactic-acid-and-triple-peptide-blend)
- Keep them apart: [Mandelic acid and triple peptide blend](https://lovi.care/skincare/au/ingredients/mandelic-acid-and-triple-peptide-blend)
- Work well together: [Coenzyme Q10 and triple peptide blend](https://lovi.care/skincare/au/ingredients/coenzyme-q10-and-triple-peptide-blend)
- Work well together: [Green tea and triple peptide blend](https://lovi.care/skincare/au/ingredients/green-tea-and-triple-peptide-blend)
- Work well together: [Vitamin E and triple peptide blend](https://lovi.care/skincare/au/ingredients/vitamin-e-and-triple-peptide-blend)
- Work well together: [Acetyl hexapeptide-3 and phytosphingosine](https://lovi.care/skincare/au/ingredients/acetyl-hexapeptide-3-and-phytosphingosine)
- Work well together: [Bio-placenta peptides and phytosphingosine](https://lovi.care/skincare/au/ingredients/bio-placenta-peptides-and-phytosphingosine)
- Work well together: [Collagen peptide and phytosphingosine](https://lovi.care/skincare/au/ingredients/collagen-peptide-and-phytosphingosine)
- Work well together: [Phytosphingosine and copper peptide](https://lovi.care/skincare/au/ingredients/phytosphingosine-and-copper-peptide)
- Work well together: [Hexapeptide and phytosphingosine](https://lovi.care/skincare/au/ingredients/hexapeptide-and-phytosphingosine)
- Work well together: [Phytosphingosine and hexapeptide-9](https://lovi.care/skincare/au/ingredients/phytosphingosine-and-hexapeptide-9)
- Work well together: [Phytosphingosine and palmitoyl pentapeptide-4](https://lovi.care/skincare/au/ingredients/phytosphingosine-and-palmitoyl-pentapeptide-4)
- Work well together: [Phytosphingosine and palmitoyl tripeptide-1](https://lovi.care/skincare/au/ingredients/phytosphingosine-and-palmitoyl-tripeptide-1)
- Work well together: [Phytosphingosine and peptide-rich plasma](https://lovi.care/skincare/au/ingredients/phytosphingosine-and-peptide-rich-plasma)
- Work well together: [Beta-sitosterol and triple peptide blend](https://lovi.care/skincare/au/ingredients/beta-sitosterol-and-triple-peptide-blend)
- Work well together: [Ceramide-building complex and triple peptide blend](https://lovi.care/skincare/au/ingredients/ceramide-building-complex-and-triple-peptide-blend)
- Work well together: [Cholesterol and triple peptide blend](https://lovi.care/skincare/au/ingredients/cholesterol-and-triple-peptide-blend)
- Work well together: [Phytosterol and triple peptide blend](https://lovi.care/skincare/au/ingredients/phytosterol-and-triple-peptide-blend)
- Work well together: [Squalene and triple peptide blend](https://lovi.care/skincare/au/ingredients/squalene-and-triple-peptide-blend)
- Work well together: [Tri-ceramide complex and triple peptide blend](https://lovi.care/skincare/au/ingredients/tri-ceramide-complex-and-triple-peptide-blend)
- Keep them apart: [Salicylic acid and triple peptide blend](https://lovi.care/skincare/au/ingredients/salicylic-acid-and-triple-peptide-blend)
- Keep them apart: [Triple peptide blend and baking soda](https://lovi.care/skincare/au/ingredients/triple-peptide-blend-and-baking-soda)
- Keep them apart: [Bleach and triple peptide blend](https://lovi.care/skincare/au/ingredients/bleach-and-triple-peptide-blend)
- Keep them apart: [Potassium hydroxide and triple peptide blend](https://lovi.care/skincare/au/ingredients/potassium-hydroxide-and-triple-peptide-blend)
- Keep them apart: [Behenyl alcohol and triple peptide blend](https://lovi.care/skincare/au/ingredients/behenyl-alcohol-and-triple-peptide-blend)
- Keep them apart: [Isopropyl alcohol and triple peptide blend](https://lovi.care/skincare/au/ingredients/isopropyl-alcohol-and-triple-peptide-blend)
- Keep them apart: [Polyvinyl alcohol and triple peptide blend](https://lovi.care/skincare/au/ingredients/polyvinyl-alcohol-and-triple-peptide-blend)
- Keep them apart: [Copper and triple peptide blend](https://lovi.care/skincare/au/ingredients/copper-and-triple-peptide-blend)
- Keep them apart: [Magnesium and triple peptide blend](https://lovi.care/skincare/au/ingredients/magnesium-and-triple-peptide-blend)
- Keep them apart: [Zinc and triple peptide blend](https://lovi.care/skincare/au/ingredients/zinc-and-triple-peptide-blend)
- Keep them apart: [Zinc sulfate and triple peptide blend](https://lovi.care/skincare/au/ingredients/zinc-sulfate-and-triple-peptide-blend)
- Keep them apart: [Benzoyl peroxide and triple peptide blend](https://lovi.care/skincare/au/ingredients/benzoyl-peroxide-and-triple-peptide-blend)
- Keep them apart: [Azelaic acid and triple peptide blend](https://lovi.care/skincare/au/ingredients/azelaic-acid-and-triple-peptide-blend)
- Keep them apart: [Protease and triple peptide blend](https://lovi.care/skincare/au/ingredients/protease-and-triple-peptide-blend)
- Keep them apart: [Superoxide dismutase and triple peptide blend](https://lovi.care/skincare/au/ingredients/superoxide-dismutase-and-triple-peptide-blend)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi checks every pairing with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this pairing advice: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/ingredients/phytosphingosine-and-triple-peptide-blend
- United Kingdom: https://lovi.care/skincare/uk/ingredients/phytosphingosine-and-triple-peptide-blend
- Ireland: https://lovi.care/skincare/ie/ingredients/phytosphingosine-and-triple-peptide-blend
- Germany: https://lovi.care/skincare/de/ingredients/phytosphingosine-and-triple-peptide-blend
- France: https://lovi.care/skincare/fr/ingredients/phytosphingosine-and-triple-peptide-blend
- Italy: https://lovi.care/skincare/it/ingredients/phytosphingosine-and-triple-peptide-blend
- Netherlands: https://lovi.care/skincare/nl/ingredients/phytosphingosine-and-triple-peptide-blend
- Spain: https://lovi.care/skincare/es/ingredients/phytosphingosine-and-triple-peptide-blend
- Canada: https://lovi.care/skincare/ca/ingredients/phytosphingosine-and-triple-peptide-blend
- Australia: https://lovi.care/skincare/au/ingredients/phytosphingosine-and-triple-peptide-blend (this page)
- Singapore: https://lovi.care/skincare/sg/ingredients/phytosphingosine-and-triple-peptide-blend
- Saudi Arabia: https://lovi.care/skincare/sa/ingredients/phytosphingosine-and-triple-peptide-blend
- United Arab Emirates: https://lovi.care/skincare/ae/ingredients/phytosphingosine-and-triple-peptide-blend
