# Acetyl hexapeptide-3 and mandelic acid

Page: https://lovi.care/skincare/au/ingredients/acetyl-hexapeptide-3-and-mandelic-acid

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Australia.

Keep them apart

Use them at different times of day by applying your acid first and your peptide later, because acids break down peptides. Acidic products clash with peptides and can make them less effective on your skin. You can switch to a milder acid or wait longer between steps.

- [All about acetyl hexapeptide-3](https://lovi.care/skincare/au/ingredients/acetyl-hexapeptide-3)
- [All about mandelic acid](https://lovi.care/skincare/au/ingredients/mandelic-acid)

### [Acetyl hexapeptide-3](https://lovi.care/skincare/au/ingredients/acetyl-hexapeptide-3) products

- [The Ordinary Multi-Peptide + Copper Peptides 1% Serum](https://lovi.care/skincare/au/p/the-ordinary/multi-peptide-copper-peptides-1-serum/for/mature-skin) — High fit — [A$54.10 at Amazon](https://www.amazon.com.au/dp/B0C9DXGXZ3?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
- [The Ordinary Multi-Peptide + HA Serum](https://lovi.care/skincare/au/p/the-ordinary/multi-peptide-ha-serum/for/dry-skin) — Superior fit — [A$29.90 at Amazon](https://www.amazon.com.au/dp/B0BLHW7JZM?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
- [Medik8 Liquid Peptides](https://lovi.care/skincare/au/p/medik8/liquid-peptides/for/oily-acne-prone-skin) — Average fit — [A$105.10 at Amazon](https://www.amazon.com.au/dp/B07YRY7P81?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
- [La Mer The Treatment Lotion](https://lovi.care/skincare/au/p/la-mer/the-treatment-lotion/for/mature-skin) — Superior fit — [A$250.99 at Amazon](https://www.amazon.com.au/dp/B0B61KKT4K?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
- [Rhode Peptide Glazing Fluid](https://lovi.care/skincare/au/p/rhode/peptide-glazing-fluid/for/mature-skin) — High fit — [A$85.17 at Amazon](https://www.amazon.com.au/dp/B0GNNW5QV3?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
- [The Ordinary Argireline Solution 10%](https://lovi.care/skincare/au/p/the-ordinary/argireline-solution-10/for/mature-skin) — Average fit — [A$16.10 at Amazon](https://www.amazon.com.au/dp/B072JH13CD?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
- [Good Molecules Super Peptide Serum](https://lovi.care/skincare/au/p/good-molecules/super-peptide-serum/for/mature-skin) — High fit
- [Clinique Smart Clinical Repair Wrinkle Correcting Serum](https://lovi.care/skincare/au/p/clinique/smart-clinical-repair-wrinkle-correcting-serum/for/mature-skin) — Average fit — [A$149.95 at Amazon](https://www.amazon.com.au/dp/B09FG8TJDD?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
- [La Mer The Renewal Oil](https://lovi.care/skincare/au/p/la-mer/the-renewal-oil/for/mature-skin) — High fit — [A$521.95 at Amazon](https://www.amazon.com.au/dp/B0163GAMI4?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
- [Estée Lauder Micro Essence Treatment Lotion](https://lovi.care/skincare/au/p/estee-lauder/micro-essence-treatment-lotion/for/oily-acne-prone-skin) — Superior fit
- [The INKEY List Collagen Peptide Serum](https://lovi.care/skincare/au/p/the-inkey-list/collagen-peptide-serum/for/dry-sensitive-skin) — High fit
- [La Mer The Eye Concentrate](https://lovi.care/skincare/au/p/la-mer/the-eye-concentrate/for/mature-skin) — High fit — [A$298.95 at Amazon](https://www.amazon.com.au/dp/B085614WX5?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)

### [Mandelic acid](https://lovi.care/skincare/au/ingredients/mandelic-acid) products

- [The Ordinary Mandelic Acid 10% + HA](https://lovi.care/skincare/au/p/the-ordinary/mandelic-acid-10-ha/for/acne-prone-skin) — Superior fit
- [Nécessaire The Body Retinol](https://lovi.care/skincare/au/p/necessaire/the-body-retinol/for/dark-spots) — Average fit
- [Good Molecules Mandelic Acid Serum](https://lovi.care/skincare/au/p/good-molecules/mandelic-acid-serum/for/dry-sensitive-skin) — Superior fit
- [Glamglow Supermud Clearing Treatment](https://lovi.care/skincare/au/p/glamglow/supermud-clearing-treatment/for/oily-skin) — High fit — [A$94.70 at Amazon](https://www.amazon.com.au/dp/B07DHSKYXR?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
- [Dermalogica PowerBright Dark Spot Peel](https://lovi.care/skincare/au/p/dermalogica/powerbright-dark-spot-peel/for/oily-skin) — Average fit
- [Sofie Pavitt Face Mandelic Clearing Serum](https://lovi.care/skincare/au/p/sofie-pavitt-face/mandelic-clearing-serum/for/oily-acne-prone-skin) — High fit
- [Cetaphil Gentle Exfoliating SA Lotion](https://lovi.care/skincare/au/p/cetaphil/gentle-exfoliating-sa-lotion/for/combination-skin) — High fit — [A$13.79 at Amazon](https://www.amazon.com.au/dp/B0DTYKC2YN?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
- [SkinCeuticals Cell Cycle Catalyst](https://lovi.care/skincare/au/p/skinceuticals/cell-cycle-catalyst/for/oily-acne-prone-skin) — Average fit
- [DIME TBT Serum](https://lovi.care/skincare/au/p/dime/tbt-serum/for/dry-sensitive-skin) — High fit
- [By Wishtrend Mandelic Acid 5% Skin Prep Water](https://lovi.care/skincare/au/p/by-wishtrend/mandelic-acid-5-skin-prep-water/for/acne-prone-skin) — High fit — [A$37.30 at Amazon](https://www.amazon.com.au/dp/B07MC4P4R8?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
- [Haruharu Wonder Black Rice Triple AHA Gentle Cleansing Gel](https://lovi.care/skincare/au/p/haruharu-wonder/black-rice-triple-aha-gentle-cleansing-gel/for/oily-acne-prone-skin) — High fit — [A$18.95 at Amazon](https://www.amazon.com.au/dp/B0CKVL9PGY?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
- [Neutrogena Bright Boost Gel Cream](https://lovi.care/skincare/au/p/neutrogena/bright-boost-gel-cream/for/acne-prone-skin) — High fit

## Questions and answers

### Can you use acetyl hexapeptide-3 and mandelic acid together?

No, you should keep [acetyl hexapeptide-3](https://lovi.care/skincare/au/ingredients/acetyl-hexapeptide-3) and [mandelic acid](https://lovi.care/skincare/au/ingredients/mandelic-acid) apart in your routine. The low pH of mandelic acid can break down the peptide bonds and reduce its effectiveness.

### Which goes first, acetyl hexapeptide-3 or mandelic acid?

Keep acetyl hexapeptide-3 and mandelic acid apart by using them in separate steps or routines, such as AM and PM, because the low pH of mandelic acid may destabilize the peptide.

### Are acetyl hexapeptide-3 and mandelic acid good for sensitive skin?

Keep acetyl hexapeptide-3 and mandelic acid apart in your routine because the low pH of mandelic acid may destabilize peptide bonds and reduce their effectiveness. Use them in separate steps or at different times of day.

## Research on acetyl hexapeptide-3 and mandelic acid

- [The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/23417317/) Acetyl hexapeptide-3 · American Journal of Clinical Dermatology, 2013
- [Comparative study of efficacy and safety of 45% mandelic acid versus 30% salicylic acid peels in mild-to-moderate acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/31553119/) Mandelic acid · Journal of Cosmetic Dermatology, 2020
- [Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin](https://pubmed.ncbi.nlm.nih.gov/33911590/) Acetyl hexapeptide-3 · Annals of Dermatology, 2019
- [Chemical peels for acne vulgaris: a systematic review of randomised controlled trials](https://pubmed.ncbi.nlm.nih.gov/29705755/) Mandelic acid · BMJ Open, 2018
- [The efficacy study of the combination of tripeptide-10-citrulline and acetyl hexapeptide-3. A prospective, randomized controlled study](https://pubmed.ncbi.nlm.nih.gov/28150423/) Acetyl hexapeptide-3 · Journal of Cosmetic Dermatology, 2017
- [The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects](https://pubmed.ncbi.nlm.nih.gov/23607739/) Acetyl hexapeptide-3 · Journal of Cosmetic and Laser Therapy, 2013

## Other combinations

- Keep them apart: [Benzoyl peroxide and mandelic acid](https://lovi.care/skincare/au/ingredients/benzoyl-peroxide-and-mandelic-acid)
- Keep them apart: [Retinol and mandelic acid](https://lovi.care/skincare/au/ingredients/retinol-and-mandelic-acid)
- Depends on the strength: [Niacinamide and mandelic acid](https://lovi.care/skincare/au/ingredients/niacinamide-and-mandelic-acid)
- Work well together: [Mandelic acid and sodium lactate](https://lovi.care/skincare/au/ingredients/mandelic-acid-and-sodium-lactate)
- Work well together: [Mandelic acid and tromethamine](https://lovi.care/skincare/au/ingredients/mandelic-acid-and-tromethamine)
- Keep them apart: [Adapalene and acetyl hexapeptide-3](https://lovi.care/skincare/au/ingredients/adapalene-and-acetyl-hexapeptide-3)
- Keep them apart: [Acetyl hexapeptide-3 and granactive retinoid](https://lovi.care/skincare/au/ingredients/acetyl-hexapeptide-3-and-granactive-retinoid)
- Keep them apart: [Acetyl hexapeptide-3 and hydroxypinacolone retinoate](https://lovi.care/skincare/au/ingredients/acetyl-hexapeptide-3-and-hydroxypinacolone-retinoate)
- Keep them apart: [Pro-retinol and acetyl hexapeptide-3](https://lovi.care/skincare/au/ingredients/pro-retinol-and-acetyl-hexapeptide-3)
- Keep them apart: [Retinal and acetyl hexapeptide-3](https://lovi.care/skincare/au/ingredients/retinal-and-acetyl-hexapeptide-3)
- Keep them apart: [Acetyl hexapeptide-3 and retinoid blend](https://lovi.care/skincare/au/ingredients/acetyl-hexapeptide-3-and-retinoid-blend)
- Depends on the strength: [Retinol and acetyl hexapeptide-3](https://lovi.care/skincare/au/ingredients/retinol-and-acetyl-hexapeptide-3)
- Keep them apart: [Tretinoin and acetyl hexapeptide-3](https://lovi.care/skincare/au/ingredients/tretinoin-and-acetyl-hexapeptide-3)
- Keep them apart: [Vitamin A and acetyl hexapeptide-3](https://lovi.care/skincare/au/ingredients/vitamin-a-and-acetyl-hexapeptide-3)
- Work well together: [Liposome and acetyl hexapeptide-3](https://lovi.care/skincare/au/ingredients/liposome-and-acetyl-hexapeptide-3)
- Work well together: [Acetyl hexapeptide-3 and microcapsule](https://lovi.care/skincare/au/ingredients/acetyl-hexapeptide-3-and-microcapsule)
- Depends on the strength: [Vitamin C and acetyl hexapeptide-3](https://lovi.care/skincare/au/ingredients/vitamin-c-and-acetyl-hexapeptide-3)
- Work well together: [Acetyl hexapeptide-3 and betaine](https://lovi.care/skincare/au/ingredients/acetyl-hexapeptide-3-and-betaine)
- Work well together: [Glycerin and acetyl hexapeptide-3](https://lovi.care/skincare/au/ingredients/glycerin-and-acetyl-hexapeptide-3)
- Work well together: [Acetyl hexapeptide-3 and hyaluronic acid](https://lovi.care/skincare/au/ingredients/acetyl-hexapeptide-3-and-hyaluronic-acid)
- Work well together: [Mandelic acid and betaine](https://lovi.care/skincare/au/ingredients/mandelic-acid-and-betaine)
- Work well together: [Glycerin and mandelic acid](https://lovi.care/skincare/au/ingredients/glycerin-and-mandelic-acid)
- Depends on the strength: [Mandelic acid and hyaluronic acid](https://lovi.care/skincare/au/ingredients/mandelic-acid-and-hyaluronic-acid)
- Depends on the strength: [Niacinamide and acetyl hexapeptide-3](https://lovi.care/skincare/au/ingredients/niacinamide-and-acetyl-hexapeptide-3)
- Work well together: [Panthenol and acetyl hexapeptide-3](https://lovi.care/skincare/au/ingredients/panthenol-and-acetyl-hexapeptide-3)
- Work well together: [Bakuchiol and acetyl hexapeptide-3](https://lovi.care/skincare/au/ingredients/bakuchiol-and-acetyl-hexapeptide-3)
- Work well together: [Arginine and acetyl hexapeptide-3](https://lovi.care/skincare/au/ingredients/arginine-and-acetyl-hexapeptide-3)
- Work well together: [Acetyl hexapeptide-3 and GABA](https://lovi.care/skincare/au/ingredients/acetyl-hexapeptide-3-and-gaba)
- Work well together: [Silk amino acids and acetyl hexapeptide-3](https://lovi.care/skincare/au/ingredients/silk-amino-acids-and-acetyl-hexapeptide-3)
- Work well together: [Taurine and acetyl hexapeptide-3](https://lovi.care/skincare/au/ingredients/taurine-and-acetyl-hexapeptide-3)
- Work well together: [Acetyl hexapeptide-3 and theanine](https://lovi.care/skincare/au/ingredients/acetyl-hexapeptide-3-and-theanine)
- Keep them apart: [AHA blend glycolic and citric acids and acetyl hexapeptide-3](https://lovi.care/skincare/au/ingredients/aha-blend-glycolic-and-citric-acids-and-acetyl-hexapeptide-3)
- Keep them apart: [Acetyl hexapeptide-3 and citric acid](https://lovi.care/skincare/au/ingredients/acetyl-hexapeptide-3-and-citric-acid)
- Keep them apart: [Glycolic acid and acetyl hexapeptide-3](https://lovi.care/skincare/au/ingredients/glycolic-acid-and-acetyl-hexapeptide-3)
- Keep them apart: [Lactic acid and acetyl hexapeptide-3](https://lovi.care/skincare/au/ingredients/lactic-acid-and-acetyl-hexapeptide-3)
- Keep them apart: [Bio-placenta peptides and mandelic acid](https://lovi.care/skincare/au/ingredients/bio-placenta-peptides-and-mandelic-acid)
- Keep them apart: [Carnosine and mandelic acid](https://lovi.care/skincare/au/ingredients/carnosine-and-mandelic-acid)
- Keep them apart: [Mandelic acid and collagen peptide](https://lovi.care/skincare/au/ingredients/mandelic-acid-and-collagen-peptide)
- Keep them apart: [Mandelic acid and copper peptide](https://lovi.care/skincare/au/ingredients/mandelic-acid-and-copper-peptide)
- Keep them apart: [Hexapeptide and mandelic acid](https://lovi.care/skincare/au/ingredients/hexapeptide-and-mandelic-acid)
- Keep them apart: [Mandelic acid and hexapeptide-9](https://lovi.care/skincare/au/ingredients/mandelic-acid-and-hexapeptide-9)
- Keep them apart: [Mandelic acid and palmitoyl pentapeptide-4](https://lovi.care/skincare/au/ingredients/mandelic-acid-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Mandelic acid and palmitoyl tripeptide-1](https://lovi.care/skincare/au/ingredients/mandelic-acid-and-palmitoyl-tripeptide-1)
- Keep them apart: [Mandelic acid and peptide-rich plasma](https://lovi.care/skincare/au/ingredients/mandelic-acid-and-peptide-rich-plasma)
- Keep them apart: [Mandelic acid and triple peptide blend](https://lovi.care/skincare/au/ingredients/mandelic-acid-and-triple-peptide-blend)
- Work well together: [Coenzyme Q10 and acetyl hexapeptide-3](https://lovi.care/skincare/au/ingredients/coenzyme-q10-and-acetyl-hexapeptide-3)
- Work well together: [Green tea and acetyl hexapeptide-3](https://lovi.care/skincare/au/ingredients/green-tea-and-acetyl-hexapeptide-3)
- Work well together: [Vitamin E and acetyl hexapeptide-3](https://lovi.care/skincare/au/ingredients/vitamin-e-and-acetyl-hexapeptide-3)
- Keep them apart: [Adapalene and mandelic acid](https://lovi.care/skincare/au/ingredients/adapalene-and-mandelic-acid)
- Keep them apart: [Mandelic acid and granactive retinoid](https://lovi.care/skincare/au/ingredients/mandelic-acid-and-granactive-retinoid)
- Keep them apart: [Mandelic acid and hydroxypinacolone retinoate](https://lovi.care/skincare/au/ingredients/mandelic-acid-and-hydroxypinacolone-retinoate)
- Keep them apart: [Pro-retinol and mandelic acid](https://lovi.care/skincare/au/ingredients/pro-retinol-and-mandelic-acid)
- Keep them apart: [Retinal and mandelic acid](https://lovi.care/skincare/au/ingredients/retinal-and-mandelic-acid)
- Keep them apart: [Mandelic acid and retinoid blend](https://lovi.care/skincare/au/ingredients/mandelic-acid-and-retinoid-blend)
- Keep them apart: [Tretinoin and mandelic acid](https://lovi.care/skincare/au/ingredients/tretinoin-and-mandelic-acid)
- Work well together: [Acetyl hexapeptide-3 and beta-sitosterol](https://lovi.care/skincare/au/ingredients/acetyl-hexapeptide-3-and-beta-sitosterol)
- Work well together: [Ceramide-building complex and acetyl hexapeptide-3](https://lovi.care/skincare/au/ingredients/ceramide-building-complex-and-acetyl-hexapeptide-3)
- Work well together: [Acetyl hexapeptide-3 and cholesterol](https://lovi.care/skincare/au/ingredients/acetyl-hexapeptide-3-and-cholesterol)
- Work well together: [Acetyl hexapeptide-3 and phytosphingosine](https://lovi.care/skincare/au/ingredients/acetyl-hexapeptide-3-and-phytosphingosine)
- Work well together: [Acetyl hexapeptide-3 and phytosterol](https://lovi.care/skincare/au/ingredients/acetyl-hexapeptide-3-and-phytosterol)
- Work well together: [Acetyl hexapeptide-3 and squalene](https://lovi.care/skincare/au/ingredients/acetyl-hexapeptide-3-and-squalene)
- Work well together: [Acetyl hexapeptide-3 and tri-ceramide complex](https://lovi.care/skincare/au/ingredients/acetyl-hexapeptide-3-and-tri-ceramide-complex)
- Work well together: [Mandelic acid and gluconolactone](https://lovi.care/skincare/au/ingredients/mandelic-acid-and-gluconolactone)
- Work well together: [Mandelic acid and lactobionic acid](https://lovi.care/skincare/au/ingredients/mandelic-acid-and-lactobionic-acid)
- Keep them apart: [Salicylic acid and acetyl hexapeptide-3](https://lovi.care/skincare/au/ingredients/salicylic-acid-and-acetyl-hexapeptide-3)
- Work well together: [Mandelic acid and cholesterol](https://lovi.care/skincare/au/ingredients/mandelic-acid-and-cholesterol)
- Work well together: [Mandelic acid and lauric acid](https://lovi.care/skincare/au/ingredients/mandelic-acid-and-lauric-acid)
- Work well together: [Linoleic acid and mandelic acid](https://lovi.care/skincare/au/ingredients/linoleic-acid-and-mandelic-acid)
- Keep them apart: [Mandelic acid and tri-ceramide complex](https://lovi.care/skincare/au/ingredients/mandelic-acid-and-tri-ceramide-complex)
- Work well together: [Arginine and mandelic acid](https://lovi.care/skincare/au/ingredients/arginine-and-mandelic-acid)
- Work well together: [Mandelic acid and GABA](https://lovi.care/skincare/au/ingredients/mandelic-acid-and-gaba)
- Work well together: [Silk amino acids and mandelic acid](https://lovi.care/skincare/au/ingredients/silk-amino-acids-and-mandelic-acid)
- Work well together: [Taurine and mandelic acid](https://lovi.care/skincare/au/ingredients/taurine-and-mandelic-acid)
- Work well together: [Mandelic acid and theanine](https://lovi.care/skincare/au/ingredients/mandelic-acid-and-theanine)
- Keep them apart: [Acetyl hexapeptide-3 and baking soda](https://lovi.care/skincare/au/ingredients/acetyl-hexapeptide-3-and-baking-soda)
- Keep them apart: [Acetyl hexapeptide-3 and bleach](https://lovi.care/skincare/au/ingredients/acetyl-hexapeptide-3-and-bleach)
- Keep them apart: [Acetyl hexapeptide-3 and potassium hydroxide](https://lovi.care/skincare/au/ingredients/acetyl-hexapeptide-3-and-potassium-hydroxide)
- Keep them apart: [Acetyl hexapeptide-3 and behenyl alcohol](https://lovi.care/skincare/au/ingredients/acetyl-hexapeptide-3-and-behenyl-alcohol)
- Keep them apart: [Acetyl hexapeptide-3 and isopropyl alcohol](https://lovi.care/skincare/au/ingredients/acetyl-hexapeptide-3-and-isopropyl-alcohol)
- Keep them apart: [Acetyl hexapeptide-3 and polyvinyl alcohol](https://lovi.care/skincare/au/ingredients/acetyl-hexapeptide-3-and-polyvinyl-alcohol)
- Work well together: [Ferulic acid and mandelic acid](https://lovi.care/skincare/au/ingredients/ferulic-acid-and-mandelic-acid)
- Work well together: [Vitamin E and mandelic acid](https://lovi.care/skincare/au/ingredients/vitamin-e-and-mandelic-acid)
- Keep them apart: [Copper and acetyl hexapeptide-3](https://lovi.care/skincare/au/ingredients/copper-and-acetyl-hexapeptide-3)
- Keep them apart: [Azelaic acid and mandelic acid](https://lovi.care/skincare/au/ingredients/azelaic-acid-and-mandelic-acid)
- Keep them apart: [Salicylic acid and mandelic acid](https://lovi.care/skincare/au/ingredients/salicylic-acid-and-mandelic-acid)
- Work well together: [Allantoin and mandelic acid](https://lovi.care/skincare/au/ingredients/allantoin-and-mandelic-acid)
- Work well together: [Mandelic acid and bisabolol](https://lovi.care/skincare/au/ingredients/mandelic-acid-and-bisabolol)
- Work well together: [Panthenol and mandelic acid](https://lovi.care/skincare/au/ingredients/panthenol-and-mandelic-acid)
- Keep them apart: [Magnesium and acetyl hexapeptide-3](https://lovi.care/skincare/au/ingredients/magnesium-and-acetyl-hexapeptide-3)
- Keep them apart: [Acetyl hexapeptide-3 and zinc](https://lovi.care/skincare/au/ingredients/acetyl-hexapeptide-3-and-zinc)
- Keep them apart: [Acetyl hexapeptide-3 and zinc sulfate](https://lovi.care/skincare/au/ingredients/acetyl-hexapeptide-3-and-zinc-sulfate)
- Keep them apart: [Benzoyl peroxide and acetyl hexapeptide-3](https://lovi.care/skincare/au/ingredients/benzoyl-peroxide-and-acetyl-hexapeptide-3)
- Keep them apart: [Azelaic acid and acetyl hexapeptide-3](https://lovi.care/skincare/au/ingredients/azelaic-acid-and-acetyl-hexapeptide-3)
- Keep them apart: [Acetyl hexapeptide-3 and protease](https://lovi.care/skincare/au/ingredients/acetyl-hexapeptide-3-and-protease)
- Keep them apart: [Acetyl hexapeptide-3 and superoxide dismutase](https://lovi.care/skincare/au/ingredients/acetyl-hexapeptide-3-and-superoxide-dismutase)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi checks every pairing with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this pairing advice: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/ingredients/acetyl-hexapeptide-3-and-mandelic-acid
- United Kingdom: https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-mandelic-acid
- Ireland: https://lovi.care/skincare/ie/ingredients/acetyl-hexapeptide-3-and-mandelic-acid
- Germany: https://lovi.care/skincare/de/ingredients/acetyl-hexapeptide-3-and-mandelic-acid
- France: https://lovi.care/skincare/fr/ingredients/acetyl-hexapeptide-3-and-mandelic-acid
- Italy: https://lovi.care/skincare/it/ingredients/acetyl-hexapeptide-3-and-mandelic-acid
- Netherlands: https://lovi.care/skincare/nl/ingredients/acetyl-hexapeptide-3-and-mandelic-acid
- Spain: https://lovi.care/skincare/es/ingredients/acetyl-hexapeptide-3-and-mandelic-acid
- Canada: https://lovi.care/skincare/ca/ingredients/acetyl-hexapeptide-3-and-mandelic-acid
- Australia: https://lovi.care/skincare/au/ingredients/acetyl-hexapeptide-3-and-mandelic-acid (this page)
- Singapore: https://lovi.care/skincare/sg/ingredients/acetyl-hexapeptide-3-and-mandelic-acid
- Saudi Arabia: https://lovi.care/skincare/sa/ingredients/acetyl-hexapeptide-3-and-mandelic-acid
- United Arab Emirates: https://lovi.care/skincare/ae/ingredients/acetyl-hexapeptide-3-and-mandelic-acid