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VR vs Sesderma

VR and Sesderma are distinguished skincare brands known for meeting evolving daily needs through considered design and meticulously engineered formulas. VR offers sensorial moisturizers best suited for combination, sensitive, and dry skin, with a standout PDRN CREAM for acne-prone skin, whereas the Spanish brand Sesderma provides advanced serums utilizing botanical extracts and active compounds for sensitive, hyperpigmented, and aging skin types, featuring the Azelac RU Serum for acne-prone skin. Both brands refine skin texture and promote radiant complexions, though they differ in their origins, specific active ingredients, and sensory experiences.

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

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This page compares some of the most popular VR and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular VR vs Sesderma products

Questions and answers

VR or Sesderma: which is better?

VR achieves a High fit for sensitive skin with its fragrance-free PDRN CREAM, whereas Sesderma achieves a High fit for acne-prone skin and skin with dark spots using its Azelac RU Serum.

What is the difference between VR and Sesderma?

VR and Sesderma differ mainly in their skin type fits and formulas, as Lovi rates VR's PDRN CREAM at High for sensitive skin with no fragrance listed, while Sesderma's Azelac RU Serum is rated High for acne-prone skin and dark spots but contains fragrance.

Which is more affordable, VR or Sesderma?

Neither VR nor Sesderma lists pricing information for the products on this page, so affordability cannot be compared.

Which causes fewer breakouts, VR or Sesderma?

For acne-prone skin, Sesderma earns a High Lovi fit with its Azelac RU Serum, whereas VR's PDRN CREAM achieves an Average fit across the products on this page. Azelaic acid helps reduce acne breakouts, and Azelac RU Serum contains fragrance.

Pharmaceutics, 2021

Which brand was founded earlier, VR or Sesderma?

Sesderma was founded in 1989 in Spain, whereas VR was founded later in 2018.

Do VR products contain fragrance compared to Sesderma?

VR has no fragrance listed in any of the products on this page, whereas the Azelac RU Serum by Sesderma includes fragrance.

How well does the VR PDRN Cream suit sensitive skin compared to the Sesderma Azelac RU Serum?

VR PDRN Cream achieves a High fit on sensitive skin, whereas Sesderma Azelac RU Serum reaches only an Average fit. Furthermore, the products on this page by VR list no fragrance in their ingredients, while the Azelac RU Serum by Sesderma includes fragrance.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

How does it fit your skin?

Scan your face, then any product: Lovi shows how well it fits you and what fits even better.