# Skintific vs Sebamed

Page: https://lovi.care/skincare/au/compare/skintific-vs-sebamed

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Australia.

Skintific and Sebamed are thoughtful skincare choices offering distinct approaches to barrier health. The former is warmly loved for its moisturizers, [serums](https://lovi.care/skincare/au/ingredients/serum), and sunscreens, suiting oily acne-prone and oily skin best with star items like the All Day Light Sunscreen Mist, 5X Ceramide Barrier Moisture Gel, and [MUGWORT](https://lovi.care/skincare/au/ingredients/mugwort). Meanwhile, the German brand founded in 1967 relies on scientifically balanced formulas for its gentle cleansers and moisturizers, which best suit sensitive, reactive, and problematic skin through a skin-neutral pH and reliable options such as the Facial Cleanser and Clear Face Care Gel. Ultimately, both differ as the first focuses on targeted concerns like dark spots and acne, while the latter maintains a steady focus on overall barrier health.

Sebamed is a German skincare brand founded in 1967 and owned by Sebapharma GmbH & Co. KG.

[sebamed.ae](https://sebamed.ae/en/article/2/Sebapharma) [sebamed.com](https://sebamed.com/en/info/company/about-us/) [en.wikipedia.org](https://en.wikipedia.org/wiki/Sebamed) [de.wikipedia.org](https://de.wikipedia.org/wiki/Sebamed)

This page compares some of the most popular Skintific and Sebamed products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg26e00df57d).

### Popular Skintific vs Sebamed products

#### Sebamed

- [Clear Face Care Gel](https://lovi.care/skincare/au/p/sebamed/clear-face-care-gel/for/oily-acne-prone-skin) — High fit
- [Facial Cleanser](https://lovi.care/skincare/au/p/sebamed/facial-cleanser/for/combination-skin) — High fit

#### Skintific

- [5X Ceramide Barrier Moisture Gel](https://lovi.care/skincare/au/p/skintific/5x-ceramide-barrier-moisture-gel/for/dry-sensitive-skin) — High fit — [A$19.90 at Amazon](https://www.amazon.com.au/dp/B0GTTJ24GR?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
- [MUGWORT](https://lovi.care/skincare/au/p/skintific/mugwort/for/dry-skin) — Average fit
- [All Day Light Sunscreen Mist](https://lovi.care/skincare/au/p/skintific/all-day-light-sunscreen-mist/for/dark-spots) — High fit
- [AHA BHA PHA LHA Peeling Solution](https://lovi.care/skincare/au/p/skintific/aha-bha-pha-lha-peeling-solution/for/oily-acne-prone-skin) — High fit — [A$19.90 at Amazon](https://www.amazon.com.au/dp/B0GWDVD11H?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
- [MATE FIT](https://lovi.care/skincare/au/p/skintific/mate-fit/for/oily-acne-prone-skin) — High fit

## Questions and answers

### Skintific or Sebamed: which is better?

Neither brand is universally better, as Skintific has a High fit for dry skin with its 5X Ceramide Barrier Moisture Gel, while Sebamed's Facial Cleanser earns a High fit for combination and oily acne-prone skin. Both brands offer products on this page with no added fragrance.

[Scientific Reports, 2022](https://pubmed.ncbi.nlm.nih.gov/35340018/) [International Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18717861/)

### What is the difference between Skintific and Sebamed?

Skintific was founded in 2021 and best fits oily and combination skin with products like its 5X Ceramide Barrier Moisture Gel, while Sebamed was founded in Germany in 1967 and offers options like its Clear Face Care Gel.

[Scientific Reports, 2022](https://pubmed.ncbi.nlm.nih.gov/35340018/)

### Skintific or Sebamed: which moisturizer is better?

For moisturizers on this page, Skintific offers High fit for dry and dry sensitive skin with its 5X Ceramide Barrier Moisture Gel, whereas Sebamed provides High fit for oily acne-prone skin with its Clear Face Care Gel. Both brands list no fragrance in their products on this page.

[Scientific Reports, 2022](https://pubmed.ncbi.nlm.nih.gov/35340018/) [International Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18717861/)

### Which is more affordable, Skintific or Sebamed?

Neither Skintific nor Sebamed lists product pricing on this page, so a direct comparison of affordability is not possible.

### Which causes fewer breakouts, Skintific or Sebamed?

Both brands offer products that help manage acne, with Skintific showing High fit for oily acne-prone skin in its peeling and mist products, and Sebamed showing High fit for oily acne-prone skin in its Clear Face Care Gel and Facial Cleanser. The products on this page list no fragrance, which is unlikely to trigger extra breakouts.

[Scientific Reports, 2022](https://pubmed.ncbi.nlm.nih.gov/35340018/) [International Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18717861/)

### Which brand is older, Skintific or Sebamed?

Sebamed is older, having been founded in Germany in 1967, whereas Skintific was founded more recently in 2021.

### Do Skintific and Sebamed products contain any fragrance?

Every product on this page for both Skintific and Sebamed lists no fragrance in its ingredients.

### Which brand offers a sunscreen product on this page?

Skintific offers a sunscreen product on this page, the All Day Light Sunscreen Mist, which has a High Lovi fit level across all skin types.

## Research behind their key ingredients

- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [Moisturizing and Antiinflammatory Properties of Cosmetic Formulations Containing Centella asiatica Extract](https://pubmed.ncbi.nlm.nih.gov/27168678/) Centella asiatica extract · Indian Journal of Pharmaceutical Sciences, 2016
- [Topical Application of Centella asiatica in Wound Healing: Recent Insights into Mechanisms and Clinical Efficacy](https://pubmed.ncbi.nlm.nih.gov/39458583/) Centella asiatica extract · Pharmaceutics, 2024
- [The effects of a topical gel containing chitosan, 0,2% chlorhexidine, allantoin and despanthenol on the wound healing process subsequent to impacted lower third molar extraction](https://pubmed.ncbi.nlm.nih.gov/27475700/) Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice · Clinical Pharmacology, 2018
- [Alteration of barrier properties, stratum corneum ceramides and microbiome composition in response to lotion application on cosmetic dry skin](https://pubmed.ncbi.nlm.nih.gov/35340018/) Ceramide · Scientific Reports, 2022
- [Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin](https://pubmed.ncbi.nlm.nih.gov/18717861/) Ceramide np, Ceramide eop · International Journal of Dermatology, 2008
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Microneedling by dermapen and glycolic acid peel for the treatment of acne scars: Comparative study](https://pubmed.ncbi.nlm.nih.gov/30548170/) Glycolic acid · Journal of Cosmetic Dermatology, 2019
- [High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin](https://pubmed.ncbi.nlm.nih.gov/11684194/) Witch hazel bark extract · Phytochemistry, 2001
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Glycolic acid · Clinical, Cosmetic and Investigational Dermatology, 2019
- [Systematic Study of Paeonol/Madecassoside Co-Delivery Nanoemulsion Transdermal Delivery System for Enhancing Barrier Repair and Anti-Inflammatory Efficacy](https://pubmed.ncbi.nlm.nih.gov/37446936/) Centella asiatica extract · Molecules, 2023
- [The pivotal role of Bifida Ferment Lysate on reinforcing the skin barrier function and maintaining homeostasis of skin defenses in vitro](https://pubmed.ncbi.nlm.nih.gov/37218728/) Bifida ferment filtrate, Bifida lysate ferment · Journal of Cosmetic Dermatology, 2023
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid](https://pubmed.ncbi.nlm.nih.gov/34348350/) Ceramide np · Skin Pharmacology and Physiology, 2022
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Efficacy and Tolerability of Topical Nicotinamide Plus Antibacterial Adhesive Agents and Zinc-Pyrrolidone Carboxylic Acid Versus Placebo as an Adjuvant Treatment for Moderate Acne Vulgaris in Indonesia: A Multicenter, Double-blind, Randomized, Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/32983333/) Zinc pca · The Journal of Clinical and Aesthetic Dermatology, 2020
- [In vivo and in vitro evaluation of octyl methoxycinnamate liposomes](https://pubmed.ncbi.nlm.nih.gov/24376350/) Ethylhexyl methoxycinnamate · International Journal of Nanomedicine, 2013
- [Effect of seasonal and geographical differences on skin and effect of treatment with an osmoprotectant: Sorbitol](https://pubmed.ncbi.nlm.nih.gov/23752031/) Sorbitol · Journal of Cosmetic Science, 2013
- [Lactobionic acid in a natural alkylpolyglucoside-based vehicle: assessing safety and efficacy aspects in comparison to glycolic acid](https://pubmed.ncbi.nlm.nih.gov/20367666/) Lactobionic acid · Journal of Cosmetic Dermatology, 2010
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025
- [A 10% Lactobionic acid-containing moisturizer reduces skin surface pH without irritation-An in vivo/in vitro study](https://pubmed.ncbi.nlm.nih.gov/30859734/) Lactobionic acid · Journal of Cosmetic Dermatology, 2019
- [Facial disbiosis and UV filters](https://pubmed.ncbi.nlm.nih.gov/39499337/) Ethylhexyl methoxycinnamate · Archives of Dermatological Research, 2024
- [Efficacy of a Topical Formulation on Skin Hydration and Barrier Function in Individuals With Xerosis: A 28-Day Randomized, Split-Leg, Untreated-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42108609/) Dipotassium glycyrrhizate · Journal of Cosmetic Dermatology, 2026
- [Low-temperature extracted Portulaca oleracea L. as a functional ingredient in facial masks for photorejuvenation of sensitive skin](https://pubmed.ncbi.nlm.nih.gov/41182319/) Portulaca oleracea extract · Cutaneous and Ocular Toxicology, 2025
- [Retrospective Review of Dermal Safety Studies of Organic Sunscreens](https://pubmed.ncbi.nlm.nih.gov/40911743/) Homosalate · Journal of Drugs in Dermatology, 2025

## The brands

- Skincare: [Skintific](https://lovi.care/skincare/au/brands/skintific)
- German skincare: [Sebamed](https://lovi.care/skincare/au/brands/sebamed)

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- [La Roche-Posay vs Skintific](https://lovi.care/skincare/au/compare/la-roche-posay-vs-skintific)
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- [Some By Mi vs Skintific](https://lovi.care/skincare/au/compare/some-by-mi-vs-skintific)
- [Some By Mi vs Sebamed](https://lovi.care/skincare/au/compare/some-by-mi-vs-sebamed)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/skintific-vs-sebamed
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- Canada: https://lovi.care/skincare/ca/compare/skintific-vs-sebamed
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- Singapore: https://lovi.care/skincare/sg/compare/skintific-vs-sebamed
- Saudi Arabia: https://lovi.care/skincare/sa/compare/skintific-vs-sebamed
- United Arab Emirates: https://lovi.care/skincare/ae/compare/skintific-vs-sebamed