# Shiseido vs Grown Alchemist

Page: https://lovi.care/skincare/au/compare/shiseido-vs-grown-alchemist

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Australia.

Shiseido and Grown Alchemist are a historic Japanese skincare brand founded in 1872 and an esteemed botanical counterpart, respectively. The brand from Japan is beloved for its sophisticated moisturizers, gentle cleansers, protective sunscreens, nourishing [serums](https://lovi.care/skincare/au/ingredients/serum), and more, all formulated with key ingredients like [glycerin](https://lovi.care/skincare/au/ingredients/glycerin), while its Australian counterpart is loved for its cleansers and serums, as well as its formulas. The former suits sensitive skin and oily skin best, owing to their balanced formulations, whereas the latter suits sensitive, dry, and combination skin best. They differ because Shiseido features standout products for particular concerns, including the Treatment Softener for acne-prone skin, the Benefiance Wrinkle Smoothing Day Cream for skin with dark spots, and the Essential Energy Hydrating Cream for mature skin, while Grown Alchemist offers the Hydra-Restore Cream Cleanser, Instant Smoothing Serum, and Gentle Gel Facial Cleanser for those same respective concerns.

Shiseido is a Japanese skincare brand founded in 1872 and owned by Shiseido Company, Limited.

[corp.shiseido.com](https://corp.shiseido.com/en/company/info/) [en.wikipedia.org](https://en.wikipedia.org/wiki/Shiseido) [marketscreener.com](https://www.marketscreener.com/quote/stock/SHISEIDO-COMPANY-LIMITED-6492328/news/Shiseido-Company-Limited-Announces-CEO-Changes-Effective-January-1-2025-47501230/)

This page compares some of the most popular Shiseido and Grown Alchemist products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pgac28808f9b).

### Popular Shiseido vs Grown Alchemist products

#### Grown Alchemist

- [Gentle Gel Facial Cleanser](https://lovi.care/skincare/au/p/grown-alchemist/gentle-gel-facial-cleanser/for/dry-sensitive-skin) — Average fit
- [Hydra-Restore Cream Cleanser](https://lovi.care/skincare/au/p/grown-alchemist/hydra-restore-cream-cleanser/for/sensitive-skin) — High fit — [A$52.00 at Amazon](https://www.amazon.com.au/dp/B00G3J8ISI?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
- [Instant Smoothing Serum](https://lovi.care/skincare/au/p/grown-alchemist/instant-smoothing-serum/for/dry-sensitive-skin) — Average fit

#### Shiseido

- [Benefiance Wrinkle Smoothing Eye Cream](https://lovi.care/skincare/au/p/shiseido/benefiance-wrinkle-smoothing-eye-cream/for/mature-skin) — High fit
- [Ultimune Power Infusing Concentrate](https://lovi.care/skincare/au/p/shiseido/ultimune-power-infusing-concentrate/for/sensitive-skin) — Average fit — [A$95.95 at Amazon](https://www.amazon.com.au/dp/B09CPC419P?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
- [VITAL PERFECTION](https://lovi.care/skincare/au/p/shiseido/vital-perfection/for/mature-skin) — Average fit — [A$107.95 at Amazon](https://www.amazon.com.au/dp/B00P0TWYB4?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
- [Clarifying Cleansing Foam](https://lovi.care/skincare/au/p/shiseido/clarifying-cleansing-foam/for/mature-skin) — Average fit
- [Essential Energy Hydrating Cream](https://lovi.care/skincare/au/p/shiseido/essential-energy-hydrating-cream/for/mature-skin) — Superior fit — [A$119.50 at Amazon](https://www.amazon.com.au/dp/B0795264YR?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
- [Activating Essence](https://lovi.care/skincare/au/p/shiseido/activating-essence/for/dry-skin) — High fit
- [FUTURE SOLUTION LX](https://lovi.care/skincare/au/p/shiseido/future-solution-lx/for/sensitive-skin) — High fit
- [Bio-Performance Advanced Super Revitalizing Cream](https://lovi.care/skincare/au/p/shiseido/bio-performance-advanced-super-revitalizing-cream/for/dry-skin) — Warning fit — [A$82.00 at Amazon](https://www.amazon.com.au/dp/B01C44OIUW?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)

## People Say

Shiseido

Grown Alchemist

- Deep hydration Mostly Mentioned Mostly Mentioned “Immediate sensation of comfort — Shiseido Benefiance Wrinkle Smoothing Eye Cream” “skin feels plump, soft and nourished, eliminates dryness, bouncy feel — Shiseido VITAL PERFECTION” “Skin feels more hydrated — Shiseido Activating Essence” “Skin version of chugging water — Grown Alchemist Instant Smoothing Serum”
- Pleasant scent Sometimes Noted Mostly Mentioned “Smells amazing — Grown Alchemist Gentle Gel Facial Cleanser” “smell is divine — Grown Alchemist Hydra-Restore Cream Cleanser” “Pleasant floral fragrance, relaxing, luxurious smell. — Shiseido Ultimune Power Infusing Concentrate”
- Luxurious texture Mostly Mentioned Often Mentioned “silky smooth, rich but non-greasy, absorbs quickly, melts into skin — Shiseido VITAL PERFECTION” “Velvety, rich cream texture — Shiseido Benefiance Wrinkle Smoothing Eye Cream” “Velvety texture — Shiseido FUTURE SOLUTION LX” “silkiest cleanser — Grown Alchemist Hydra-Restore Cream Cleanser”
- Gentle on skin Rarely Noted Mostly Mentioned “Perfect for sensitive skin — Grown Alchemist Gentle Gel Facial Cleanser” “calms my skin down — Grown Alchemist Hydra-Restore Cream Cleanser” “No irritation — Shiseido Essential Energy Hydrating Cream”
- Lightweight texture Sometimes Noted Often Mentioned “Airy-soft texture — Shiseido Essential Energy Hydrating Cream” “absorbs quickly — Shiseido White Lucent Brightening Gel Cream” “Very light weight — Grown Alchemist Instant Smoothing Serum”
- Anti-aging and firming Often Mentioned Sometimes Noted “Smoothed out crow's feet — Shiseido Benefiance Wrinkle Smoothing Eye Cream” “Skin looks brighter, more radiant, and "glowy." — Shiseido Ultimune Power Infusing Concentrate” “tighter jawline, lifted appearance, improved elasticity, less sagging — Shiseido VITAL PERFECTION” “Smooths out fine lines — Grown Alchemist Instant Smoothing Serum”
- High price point Mostly Mentioned Often Mentioned “expensive for what it is — Grown Alchemist Hydra-Restore Cream Cleanser” “A bit pricey — Grown Alchemist Instant Smoothing Serum” “Very expensive for the size — Shiseido Benefiance Wrinkle Smoothing Eye Cream”
- Strong fragrance and scent issues Often Mentioned Often Mentioned “Too perfumy notes — Grown Alchemist Gentle Gel Facial Cleanser” “smells medicinal — Grown Alchemist Hydra-Restore Cream Cleanser” “old lady smell — Shiseido Eudermine Revitalizing Essence”
- Packaging and bottle issues Sometimes Noted Often Mentioned “heavy to travel — Shiseido Eudermine Revitalizing Essence” “Heavy bottle but plastic pump, cannot see remaining product, straw too short to get last drops. — Shiseido Ultimune Power Infusing Concentrate” “heavy jar, waste of plastic, faulty pump (on dispenser versions) — Shiseido VITAL PERFECTION” “tube cracks easily — Grown Alchemist Hydra-Restore Cream Cleanser”

## Questions and answers

### Shiseido or Grown Alchemist: which is better?

Shiseido is generally better for deep hydration and anti-aging care, whereas Grown Alchemist is better for gentle, fragrance-free routines. Topical [hyaluronic acid](https://lovi.care/skincare/au/ingredients/hyaluronic-acid) in the products on this page helps improve skin quality and signs of aging.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### What is the difference between Shiseido and Grown Alchemist?

Shiseido offers a wide range of products with luxurious textures that provide deep hydration and anti-aging benefits, while Grown Alchemist focuses on gentle, fragrance-free cleansers that are well-suited for sensitive skin. Topical hyaluronic acid, a key ingredient featured across Shiseido products, helps improve skin quality and signs of aging.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Shiseido or Grown Alchemist: which cleanser is better?

Shiseido features cleansers that Lovi rates as High for oily and combination skin, such as the Deep Cleansing Foam. Grown Alchemist offers fragrance-free options like the Hydra-Restore Cream Cleanser, which Lovi rates as High for dry, sensitive, and mature skin.

### Which is more affordable, Shiseido or Grown Alchemist?

Grown Alchemist is more affordable on this page, as high price point is noted as a negative review theme for Shiseido.

### Which causes fewer breakouts, Shiseido or Grown Alchemist?

Grown Alchemist is unlikely to cause breakouts because all the products on this page are fragrance-free and gentle, whereas Shiseido features several products that reviewers note can occasionally lead to skin irritation.

### Between Shiseido and Grown Alchemist, which brand offers fragrance-free products?

Between the two brands, Grown Alchemist offers fragrance-free options because every product on this page lists no fragrance in its ingredients.

### Which brand performs better for deep hydration according to reviewer themes?

Shiseido performs better for deep hydration compared to Grown Alchemist according to reviewer themes on this page.

### When comparing the two skincare lines, which brand is associated with anti-aging and firming benefits?

When comparing the products on this page, Shiseido is the brand associated with anti-aging and firming benefits.

## Research behind their key ingredients

- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Final report on the safety assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate](https://pubmed.ncbi.nlm.nih.gov/11766131/) Benzyl alcohol · International Journal of Toxicology, 2001
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate molecule · Dermatologic Therapy, 2022
- [Caffeine's mechanisms of action and its cosmetic use](https://pubmed.ncbi.nlm.nih.gov/23075568/) Caffeine · Skin Pharmacology and Physiology, 2013
- [Peroxidated squalene induces the production of inflammatory mediators in HaCaT keratinocytes: a possible role in acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/16778793/) Squalane · The Journal of Investigative Dermatology, 2006
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Tocopherol · Journal of Cosmetic Dermatology, 2020
- [Psychophysical study of the effects of topical application of menthol in healthy volunteers](https://pubmed.ncbi.nlm.nih.gov/16527405/) Menthol · Pain, 2006
- [Evaluation of efficacy and tolerance of a nighttime topical antioxidant containing resveratrol, baicalin, and vitamin e for treatment of mild to moderately photodamaged skin](https://pubmed.ncbi.nlm.nih.gov/25607790/) Scutellaria baicalensis root extract · Journal of Drugs in Dermatology, 2014
- [Ethanol extracts of Sanguisorba officinalis L. suppress TNF-α/IFN-γ-induced pro-inflammatory chemokine production in HaCaT cells](https://pubmed.ncbi.nlm.nih.gov/26655409/) Sanguisorba officinalis root extract · Phytomedicine, 2015
- [Skin barrier disruption by sodium lauryl sulfate-exposure alters the expressions of involucrin, transglutaminase 1, profilaggrin, and kallikreins during the repair phase in human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/18007579/) Sodium lauryl sulfate · The Journal of Investigative Dermatology, 2008
- [Panax ginseng induces human Type I collagen synthesis through activation of Smad signaling](https://pubmed.ncbi.nlm.nih.gov/16890388/) Panax ginseng root extract · Journal of Ethnopharmacology, 2007
- [Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin](https://pubmed.ncbi.nlm.nih.gov/33037252/) Squalane · Scientific Reports, 2020
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf extract · Clinical Pharmacology, 2018
- [Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls](https://pubmed.ncbi.nlm.nih.gov/18631247/) Camellia sinensis leaf extract · Experimental Dermatology, 2009
- [A review of topical high-concentration L-menthol as a translational model of cold allodynia and hyperalgesia](https://pubmed.ncbi.nlm.nih.gov/23963768/) Menthol · European Journal of Pain, 2014
- [Design, preparation, and evaluation of liposomal gel formulations for treatment of acne: in vitro and in vivo studies](https://pubmed.ncbi.nlm.nih.gov/30442066/) Lauric acid · Drug Development and Industrial Pharmacy, 2019
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [In vitro antioxidant, collagenase inhibition, and in vivo anti-wrinkle effects of combined formulation containing Punica granatum, Ginkgo biloba, Ficus carica, and Morus alba fruits extract](https://pubmed.ncbi.nlm.nih.gov/26203268/) Ginkgo biloba leaf extract · Clinical, Cosmetic and Investigational Dermatology, 2015
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [Another Reason for Using Caffeine in Dermocosmetics: Sunscreen Adjuvant](https://pubmed.ncbi.nlm.nih.gov/31130869/) Caffeine · Frontiers in Physiology, 2019
- [High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin](https://pubmed.ncbi.nlm.nih.gov/11684194/) Witch hazel leaf extract · Phytochemistry, 2001
- [Efficacy of olive leaf extract-containing cream for facial rejuvenation: A pilot study](https://pubmed.ncbi.nlm.nih.gov/32333467/) Olive leaf extract · Journal of Cosmetic Dermatology, 2020
- [Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications](https://pubmed.ncbi.nlm.nih.gov/25817264/) Palmitoyl tetrapeptide-7, Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2015
- [Changes in Skin Barrier Function after Repeated Exposition to Phospholipid-Based Surfactants and Sodium Dodecyl Sulfate In Vivo and Corneocyte Surface Analysis by Atomic Force Microscopy](https://pubmed.ncbi.nlm.nih.gov/33804924/) Sodium lauryl sulfate · Pharmaceutics, 2021
- [A novel model of inflammatory pain in human skin involving topical application of sodium lauryl sulfate](https://pubmed.ncbi.nlm.nih.gov/20358390/) Sodium lauryl sulfate · Inflammation Research, 2010
- [Subclinical, non-erythematous irritation with an open assay model (washing): sodium lauryl sulfate (SLS) versus sodium laureth sulfate (SLES)](https://pubmed.ncbi.nlm.nih.gov/11278060/) Sodium laureth sulfate · Food and Chemical Toxicology, 2001
- [A Rose Extract Protects the Skin against Stress Mediators: A Potential Role of Olfactory Receptors](https://pubmed.ncbi.nlm.nih.gov/33081083/) Rose bud · Molecules, 2020
- [Antiacne and antiblotch activities of a formulated combination of Aloe barbadensis leaf powder, Garcinia mangostana peel extract, and Camellia sinensis leaf extract](https://pubmed.ncbi.nlm.nih.gov/31239743/) Camellia sinensis leaf extract · Clinical, Cosmetic and Investigational Dermatology, 2019
- [Is benzyl alcohol a significant contact sensitizer?](https://pubmed.ncbi.nlm.nih.gov/35080274/) Benzyl alcohol · Journal of the European Academy of Dermatology and Venereology, 2022
- [In vivo and in vitro evaluation of octyl methoxycinnamate liposomes](https://pubmed.ncbi.nlm.nih.gov/24376350/) Ethylhexyl methoxycinnamate · International Journal of Nanomedicine, 2013
- [A retrospective assessment and comparison of the effectiveness of benzoyl peroxide; the combination of topical niacinamide, gallic acid, and lauric acid; and the combination of benzoyl peroxide and erythromycin in acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/32390309/) Lauric acid · Dermatologic Therapy, 2020
- [Effect of a botanical cleansing lotion on skin sebum and erythema of the face: A randomized controlled blinded half-side comparison](https://pubmed.ncbi.nlm.nih.gov/30022595/) Willow bark extract · Journal of Cosmetic Dermatology, 2019
- [Anti-Inflammatory Effect of a Novel Topical Herbal Composition (VEL-091604) Consisting of Gentian Root, Licorice Root and Willow Bark Extract](https://pubmed.ncbi.nlm.nih.gov/30690691/) Willow bark extract · Planta Medica, 2019
- [Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast](https://pubmed.ncbi.nlm.nih.gov/40363772/) Squalane · Molecules, 2025
- [Synergetic Effects of Aloe Vera Extract with Trimethylglycine for Targeted Aquaporin 3 Regulation and Long-Term Skin Hydration](https://pubmed.ncbi.nlm.nih.gov/38611819/) Betaine · Molecules, 2024
- [Microbicidal activity of tripotassium phosphate and fatty acids toward spoilage and pathogenic bacteria associated with poultry](https://pubmed.ncbi.nlm.nih.gov/16013388/) Myristic acid · Journal of Food Protection, 2005
- [Clinical Development and Evaluation of a Multi-Component Dissolving Microneedle Patch for Skin Pigmentation Disorders](https://pubmed.ncbi.nlm.nih.gov/37571190/) 2-o-ethyl ascorbic acid · Polymers, 2023
- [Synergistic approach for acne vulgaris treatment using glycerosomes loaded with lincomycin and lauric acid: Formulation, in silico, in vitro, LC-MS/MS skin deposition assay and in vivo evaluation](https://pubmed.ncbi.nlm.nih.gov/37805147/) Lauric acid · International Journal of Pharmaceutics, 2023
- [Noninvasive evaluation of the influence of aucubin-containing cosmetic macroemulsion on selected skin parameters](https://pubmed.ncbi.nlm.nih.gov/32750209/) Plantago extract · Journal of Cosmetic Dermatology, 2021
- [Effect of hydroxypropyl-β-cyclodextrin in fluid and semi-solid submicron emulsions on physiological skin parameters during regular in vivo application](https://pubmed.ncbi.nlm.nih.gov/33236374/) Cyclodextrin · International Journal of Cosmetic Science, 2021
- [Formulation of Ascorbic Acid and Betaine-based Therapeutic Deep Eutectic System for Enhanced Transdermal Delivery of Ascorbic Acid](https://pubmed.ncbi.nlm.nih.gov/38794349/) Betaine · Pharmaceutics, 2024
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Anatomical site differences of sodium lauryl sulfate-induced irritation: randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/30637727/) Sodium lauryl sulfate · The British Journal of Dermatology, 2019
- [A controlled, three-part trial to investigate the barrier function and skin hydration properties of six skin protectants](https://pubmed.ncbi.nlm.nih.gov/16439809/) Dimethicone · Ostomy/wound Management, 2005
- [The use of different concentrations of betaine as a reducing irritation agent in soaps monitored visually and non-invasively](https://pubmed.ncbi.nlm.nih.gov/12535284/) Betaine · Skin Research and Technology, 2003
- [Skin recovery by Lavandula angustifolia leaf callus extract: Redox control of Nrf2 signaling](https://pubmed.ncbi.nlm.nih.gov/40345503/) Lavandula angustifolia oil lavender oil · Free Radical Biology & Medicine, 2025
- [Rosa gallica and its active compound, cyanidin-3,5-O-diglucoside, improve skin hydration via the GLK signaling pathway](https://pubmed.ncbi.nlm.nih.gov/36573713/) Rose bud · BioFactors, 2023
- [Moisturizing Effects of Diglycerol Combined with Glycerol on Human Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/27430380/) Diglycerin · Journal of Oleo Science, 2016
- [Ginkgo biloba leaves extract's cosmeceutical evaluation: a preliminary assessments on human volunteers towards achieving improved skin condition and rejuvenation](https://pubmed.ncbi.nlm.nih.gov/37074796/) Ginkgo biloba leaf extract · Drug Development and Industrial Pharmacy, 2023
- [Combining Topical and Oral Botanicals for Skin Redness, Pigmentation, Sleep, and Mood: A Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/36431167/) Theanine · Journal of Clinical Medicine, 2022
- [Antioxidant and membrane-protective effects of the 3-O-ethyl ascorbic acid-cannabigerol system on UVB-irradiated human keratinocytes](https://pubmed.ncbi.nlm.nih.gov/39778604/) 2-o-ethyl ascorbic acid · Free Radical Biology & Medicine, 2025
- [Clinical efficacy of herbal extract cream on the skin hydration, elasticity, thickness, and dermis density for aged skin: A randomized controlled double-blind study](https://pubmed.ncbi.nlm.nih.gov/30636339/) Botanical extracts · Journal of Cosmetic Dermatology, 2019
- [Functional properties and skin care effects of sodium trehalose sulfate](https://pubmed.ncbi.nlm.nih.gov/38606717/) Trehalose · Skin Research and Technology, 2024
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Transdermal Delivery of Baicalin Based on Bio-Vesicles and Its Efficacy in Antiaging of the Skin](https://pubmed.ncbi.nlm.nih.gov/39946269/) Scutellaria baicalensis root extract · Journal of Cosmetic Dermatology, 2025
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Effect of isosecotanapartholide isolated from Artemisia princeps Pampanini on IL‑33 production and STAT‑1 activation in HaCaT keratinocytes](https://pubmed.ncbi.nlm.nih.gov/28447741/) Artemisia princeps leaf extract · Molecular Medicine Reports, 2017
- [Liposomal formulation of a vitamin C derivative: a promising strategy to increase skin permeability](https://pubmed.ncbi.nlm.nih.gov/39985147/) 2-o-ethyl ascorbic acid · Journal of Liposome Research, 2025
- [Thermostable hyaluronic acid-based dissolving microneedles with high-loading capacity: design, optimization, and transdermal delivery of anti-aging ingredients](https://pubmed.ncbi.nlm.nih.gov/41628877/) 2-o-ethyl ascorbic acid · International Journal of Biological Macromolecules, 2026
- [Influence of the emulsifier on nanostructure and clinical application of liquid crystalline emulsions](https://pubmed.ncbi.nlm.nih.gov/36918671/) Camellia seed oil · Scientific Reports, 2023
- [Development and efficacy assessments of tea seed oil makeup remover](https://pubmed.ncbi.nlm.nih.gov/27988044/) Camellia seed oil · Annales Pharmaceutiques Francaises, 2017
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [Potassium 4-Methoxysalicylate (4MSK) Exerts a Skin Lightening Effect by Acting on Melanocytes and Keratinocytes](https://pubmed.ncbi.nlm.nih.gov/40071590/) Potassium methoxysalicylate · Journal of Cosmetic Dermatology, 2025
- [New Chalcone-Derived Molecule for the Topical Regulation of Hyperpigmentation and Skin Aging](https://pubmed.ncbi.nlm.nih.gov/39598529/) Angelica keiskei leaf extract · Pharmaceutics, 2024
- [Mitigation of ultraviolet-induced erythema and inflammation by para-hydroxycinnamic acid in human skin](https://pubmed.ncbi.nlm.nih.gov/39138602/) Ethylhexyl methoxycinnamate · International Journal of Cosmetic Science, 2025
- [Facial disbiosis and UV filters](https://pubmed.ncbi.nlm.nih.gov/39499337/) Ethylhexyl methoxycinnamate, Octocrylene · Archives of Dermatological Research, 2024
- [Effects of fermented tea seed oil on the skin lipid barrier and microbiome of sensitive skin](https://pubmed.ncbi.nlm.nih.gov/41319188/) Camellia seed oil · International Journal of Cosmetic Science, 2026
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026
- [Mechanistic understanding and peptide ingredient screening for type III collagen via biological knowledge graph and molecular docking](https://pubmed.ncbi.nlm.nih.gov/42683869/) Palmitoyl tetrapeptide-7, Palmitoyl tripeptide-1 · International Journal of Cosmetic Science, 2026
- [Efficacy of anti-sebum moisturizing cream containing 2% l-carnitine and 5% epigallocatechin gallate in seborrhea: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/37194909/) Uji green tea extract · Journal of Cosmetic Dermatology, 2023
- [Efficacy of a Topical Formulation on Skin Hydration and Barrier Function in Individuals With Xerosis: A 28-Day Randomized, Split-Leg, Untreated-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42108609/) Dipotassium glycyrrhizate · Journal of Cosmetic Dermatology, 2026
- [Impact of dermal emulsions containing diacyl phospholipids, mono acyl phospholipids, sodium lauryl ether sulfate and polysorbate 80 in combination with UVA irradiation on human skin physiology in vivo: A pilot study](https://pubmed.ncbi.nlm.nih.gov/42617898/) Sodium laureth sulfate · International Journal of Pharmaceutics, 2026
- [Retrospective Review of Dermal Safety Studies of Organic Sunscreens](https://pubmed.ncbi.nlm.nih.gov/40911743/) Homosalate · Journal of Drugs in Dermatology, 2025

## The brands

- Japanese skincare: [Shiseido](https://lovi.care/skincare/au/brands/shiseido)
- Skincare: [Grown Alchemist](https://lovi.care/skincare/au/brands/grown-alchemist)

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- [COSRX vs Shiseido](https://lovi.care/skincare/au/compare/cosrx-vs-shiseido)
- [COSRX vs Grown Alchemist](https://lovi.care/skincare/au/compare/cosrx-vs-grown-alchemist)
- [CeraVe vs Shiseido](https://lovi.care/skincare/au/compare/cerave-vs-shiseido)
- [CeraVe vs Grown Alchemist](https://lovi.care/skincare/au/compare/cerave-vs-grown-alchemist)
- [La Roche-Posay vs Shiseido](https://lovi.care/skincare/au/compare/la-roche-posay-vs-shiseido)
- [La Roche-Posay vs Grown Alchemist](https://lovi.care/skincare/au/compare/la-roche-posay-vs-grown-alchemist)
- [Dr. Althea vs Shiseido](https://lovi.care/skincare/au/compare/dr-althea-vs-shiseido)
- [Dr. Althea vs Grown Alchemist](https://lovi.care/skincare/au/compare/dr-althea-vs-grown-alchemist)
- [Some By Mi vs Shiseido](https://lovi.care/skincare/au/compare/some-by-mi-vs-shiseido)
- [Some By Mi vs Grown Alchemist](https://lovi.care/skincare/au/compare/some-by-mi-vs-grown-alchemist)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/shiseido-vs-grown-alchemist
- United Kingdom: https://lovi.care/skincare/uk/compare/shiseido-vs-grown-alchemist
- Ireland: https://lovi.care/skincare/ie/compare/shiseido-vs-grown-alchemist
- Germany: https://lovi.care/skincare/de/compare/shiseido-vs-grown-alchemist
- France: https://lovi.care/skincare/fr/compare/shiseido-vs-grown-alchemist
- Italy: https://lovi.care/skincare/it/compare/shiseido-vs-grown-alchemist
- Netherlands: https://lovi.care/skincare/nl/compare/shiseido-vs-grown-alchemist
- Spain: https://lovi.care/skincare/es/compare/shiseido-vs-grown-alchemist
- Canada: https://lovi.care/skincare/ca/compare/shiseido-vs-grown-alchemist
- Australia: https://lovi.care/skincare/au/compare/shiseido-vs-grown-alchemist (this page)
- Singapore: https://lovi.care/skincare/sg/compare/shiseido-vs-grown-alchemist
- Saudi Arabia: https://lovi.care/skincare/sa/compare/shiseido-vs-grown-alchemist
- United Arab Emirates: https://lovi.care/skincare/ae/compare/shiseido-vs-grown-alchemist