# Paula's Choice vs Medik8

Page: https://lovi.care/skincare/au/compare/paula-s-choice-vs-medik8

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Australia.

Paula's Choice and Medik8 are established skincare brands offering [serums](https://lovi.care/skincare/au/ingredients/serum), moisturizers, toners, and more. The American brand, founded in 1995, builds its formulas around [hyaluronic acid](https://lovi.care/skincare/au/ingredients/hyaluronic-acid), [glycerin](https://lovi.care/skincare/au/ingredients/glycerin), and [vitamin c](https://lovi.care/skincare/au/ingredients/vitamin-c), suiting oily and acne-prone skin best. Meanwhile, the British brand, founded in 2009, relies on hyaluronic acid to cater primarily to dry and dry sensitive skin. Both brands differ in their key ingredients, with glycerin in the former significantly increasing skin hydration and restoring barrier function, and hyaluronic acid in the latter lengthening toxin wrinkle effect duration.

Paula's Choice is an American skincare brand founded in 1995 and owned by Unilever since 2021.

[unilever.com](https://www.unilever.com/news/press-and-media/press-releases/2021/unilever-to-acquire-paulas-choice-skincare/) [tracxn.com](https://tracxn.com/d/companies/paulas-choice/__3NzlGcC2yhs-Z9XjkOCar6Dxe0DJgowfl0PAX9OD5s8)

Medik8 is a British skincare brand founded in 2009 and owned by L'Oréal Groupe since 2025.

[loreal.com](https://www.loreal.com/en/press-release/group/l-oreal-groupe-to-acquire-a-majority-stake-in-medik8/) [medik8.com](https://www.medik8.com/pages/founders-story) [tracxn.com](https://tracxn.com/d/companies/medik8/__vqs3N9eL3EfvIq0IoeUPADts7CrlGbzm7kjy9M9QY8o)

This page compares some of the most popular Paula's Choice and Medik8 products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pge076fdac7b).

### Popular Paula's Choice vs Medik8 products

#### Paula's Choice

- [Skin Perfecting 2% BHA Liquid Exfoliant](https://lovi.care/skincare/au/p/paula-s-choice/skin-perfecting-2-bha-liquid-exfoliant/for/oily-skin) — Superior fit — [A$54.00 at Amazon](https://www.amazon.com.au/dp/B0CJH3R48Z?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
- [1% Retinol Treatment](https://lovi.care/skincare/au/p/paula-s-choice/1-retinol-treatment/for/dark-spots) — Superior fit — [A$98.00 at Amazon](https://www.amazon.com.au/dp/B00L5O2ZXK?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
- [10% Azelaic Acid Booster](https://lovi.care/skincare/au/p/paula-s-choice/10-azelaic-acid-booster/for/acne-prone-skin) — High fit — [A$64.00 at Amazon](https://www.amazon.com.au/dp/B00V4PNAI4?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
- [C15 Super Booster](https://lovi.care/skincare/au/p/paula-s-choice/c15-super-booster/for/mature-skin) — High fit — [A$84.00 at Amazon](https://www.amazon.com.au/dp/B0H6N4XPLG?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
- [CLEAR Pore Normalizing Cleanser](https://lovi.care/skincare/au/p/paula-s-choice/clear-pore-normalizing-cleanser/for/oily-acne-prone-skin) — Superior fit — [A$32.00 at Amazon](https://www.amazon.com.au/dp/B07R74CPPY?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
- [10% Niacinamide Booster](https://lovi.care/skincare/au/p/paula-s-choice/10-niacinamide-booster/for/dry-sensitive-skin) — Superior fit — [A$76.00 at Amazon](https://www.amazon.com.au/dp/B01GF1EOB8?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
- [Weightless Body Treatment 2% BHA](https://lovi.care/skincare/au/p/paula-s-choice/weightless-body-treatment-2-bha/for/oily-acne-prone-skin) — Average fit — [A$54.00 at Amazon](https://www.amazon.com.au/dp/B00CS5U172?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
- [Skin Balancing Pore-Reducing Toner](https://lovi.care/skincare/au/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — [A$42.00 at Amazon](https://www.amazon.com.au/dp/B008EPPIQ4?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)

#### Medik8

- [Liquid Peptides](https://lovi.care/skincare/au/p/medik8/liquid-peptides/for/oily-acne-prone-skin) — Average fit — [A$105.10 at Amazon](https://www.amazon.com.au/dp/B07YRY7P81?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
- [CRYSTAL RETINAL 3](https://lovi.care/skincare/au/p/medik8/crystal-retinal-3/for/mature-skin) — High fit
- [C-Tetra Serum](https://lovi.care/skincare/au/p/medik8/c-tetra-serum/for/dry-sensitive-skin) — Average fit — [A$84.27 at Amazon](https://www.amazon.com.au/dp/B094GHRY9B?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
- [Bakuchiol Peptides](https://lovi.care/skincare/au/p/medik8/bakuchiol-peptides/for/dry-skin) — Superior fit — [A$91.10 at Amazon](https://www.amazon.com.au/dp/B08FHWV9KD?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
- [Crystal Retinal Ceramide Eye 3](https://lovi.care/skincare/au/p/medik8/crystal-retinal-ceramide-eye-3/for/mature-skin) — High fit
- [Oxy-R Peptides](https://lovi.care/skincare/au/p/medik8/oxy-r-peptides/for/mature-skin) — Superior fit
- [Total Moisture Daily Facial Cream](https://lovi.care/skincare/au/p/medik8/total-moisture-daily-facial-cream/for/mature-skin) — High fit
- [Hydr8 B5 Intense](https://lovi.care/skincare/au/p/medik8/hydr8-b5-intense/for/dry-skin) — Superior fit

## People Say

Paula's Choice

Medik8

- Hydration and Moisture Mostly Mentioned Mostly Mentioned “Provides an internal level of hydration without leaving any heavy finish. — Paula's Choice Skin Balancing Pore-Reducing Toner” “Absorbs quickly and leaves no greasy residue behind. — Paula's Choice Clear Oil-Free Moisturizer” “Restores moisture — Medik8 Liquid Peptides” “absorbed effortlessly — Medik8 Total Moisture Daily Facial Cream”
- Texture and Pores Mostly Mentioned Often Mentioned “cleared my bumps — Paula's Choice Skin Perfecting 2% BHA Liquid Exfoliant” “skin becomes very smooth — Paula's Choice 1% Retinol Treatment” “pores look smaller — Paula's Choice 10% Niacinamide Booster” “smoother skin — Medik8 Surface Radiance Cleanse”
- Gentle Formulation Often Mentioned Mostly Mentioned “zero irritation or peeling — Medik8 CRYSTAL RETINAL 3” “only Vitamin C my sensitive skin can tolerate — Medik8 C-Tetra Serum” “Best retinol replacement — Medik8 Bakuchiol Peptides” “Finally a vitamin C product I can use — Paula's Choice 25% Vitamin C + Glutathione Clinical Serum”
- Glow and Brightening Often Mentioned Often Mentioned “visible glow — Paula's Choice C15 Super Booster” “acne scars faded — Paula's Choice 10% Azelaic Acid Booster” “I wake up glowing. It adds back that youthful bloom that I've lost. — Medik8 Sleep Glycolic” “unlocked a serious glow — Medik8 C-Tetra Serum”
- Anti-Aging and Firming Sometimes Noted Often Mentioned “skin looks plumper — Paula's Choice Pro-Collagen Multi-Peptide Booster” “softens lines and wrinkles — Paula's Choice 1% Retinol Treatment” “Reduces fine lines — Medik8 Liquid Peptides” “Plumps skin with moisture — Medik8 Bakuchiol Peptides”
- Acne and Cleansing Often Mentioned Rarely Noted “Helped clear my cystic acne — Paula's Choice CLEAR Pore Normalizing Cleanser” “heals blemishes faster — Paula's Choice Skin Perfecting 2% BHA Liquid Exfoliant” “Removes all my makeup easily — Paula's Choice CLEAR Pore Normalizing Cleanser” “pores feel cleaner — Medik8 Surface Radiance Cleanse”
- High Price Point Mostly Mentioned Often Mentioned “Expensive per bottle — Medik8 Liquid Peptides” “very expensive for amount — Medik8 CRYSTAL RETINAL 3” “hefty price tag — Medik8 C-Tetra Serum” “tiny tube — Paula's Choice 10% Azelaic Acid Booster”
- Dryness and Flaking Sometimes Noted Sometimes Noted “slightly drying — Medik8 Surface Radiance Cleanse” “need a thick moisturizer — Medik8 CRYSTAL RETINAL 3” “need more moisture — Medik8 Crystal Retinal Ceramide Eye 3” “peeling and flaking — Paula's Choice 1% Retinol Treatment”
- Packaging Issues Sometimes Noted Sometimes Noted “dropper leaks — Paula's Choice C15 Super Booster” “dropper can be unpredictable — Paula's Choice Pro-Collagen Multi-Peptide Booster” “Glass bottle breaks easily — Medik8 Liquid Peptides” “hard to get last bit — Medik8 CRYSTAL RETINAL 3”

### Paula's Choice vs Medik8 routines for dry skin

#### Medik8-focused routine

- Cleanser: [La Roche-Posay Toleriane Hydrating Gentle Cleanser](https://lovi.care/skincare/au/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/dry-skin) — Superior fit — [A$26.59 at Amazon](https://www.amazon.com.au/dp/B075Q18R92?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Pyunkang Yul Calming Deep Moisture Toner](https://lovi.care/skincare/au/p/pyunkang-yul/calming-deep-moisture-toner/for/dry-skin) — Superior fit — [A$23.99 at Amazon](https://www.amazon.com.au/dp/B08Q6WZ6J1?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [d'Alba First Spray Serum](https://lovi.care/skincare/au/p/d-alba/first-spray-serum/for/dry-skin) — Superior fit — [A$26.09 at Amazon](https://www.amazon.com.au/dp/B0BFQ9RD5B?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Bioderma Photoderm Mineral Fluide SPF50+](https://lovi.care/skincare/au/p/bioderma/photoderm-mineral-fluide-spf50/for/dry-skin) — Superior fit — [A$24.49 at Amazon](https://www.amazon.com.au/dp/B0GP9GJWTD?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/au/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — [A$27.35 at Amazon](https://www.amazon.com.au/dp/B084Q16G8D?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Bakuchiol Peptides](https://lovi.care/skincare/au/p/medik8/bakuchiol-peptides/for/dry-skin) — Superior fit — [A$91.10 at Amazon](https://www.amazon.com.au/dp/B08FHWV9KD?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [FANCL Facial Washing Powder](https://lovi.care/skincare/au/p/fancl/facial-washing-powder/for/dry-skin) — High fit — [A$35.50 at Amazon](https://www.amazon.com.au/dp/B01KTJXVI4?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Once a week
- Nourishing Mask: [MEDIHEAL Vita Essential Mask](https://lovi.care/skincare/au/p/mediheal/vita-essential-mask/for/dry-skin) — Superior fit — [A$28.48 at Amazon](https://www.amazon.com.au/dp/B09XWPL5VN?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Once a week

#### Paula's Choice-focused routine

- Cleanser: [CLEAR Pore Normalizing Cleanser](https://lovi.care/skincare/au/p/paula-s-choice/clear-pore-normalizing-cleanser/for/dry-skin) — Caution fit — [A$32.00 at Amazon](https://www.amazon.com.au/dp/B07R74CPPY?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Skin Recovery Enriched Calming Toner](https://lovi.care/skincare/au/p/paula-s-choice/skin-recovery-enriched-calming-toner/for/dry-skin) — Superior fit — [A$42.00 at Amazon](https://www.amazon.com.au/dp/B00949CII0?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [Replenishing Moisturizer](https://lovi.care/skincare/au/p/paula-s-choice/replenishing-moisturizer/for/dry-skin) — High fit — [A$65.00 at Amazon](https://www.amazon.com.au/dp/B008EPPPDK?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Bioderma Photoderm Mineral Fluide SPF50+](https://lovi.care/skincare/au/p/bioderma/photoderm-mineral-fluide-spf50/for/dry-skin) — Superior fit — [A$24.49 at Amazon](https://www.amazon.com.au/dp/B0GP9GJWTD?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/au/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — [A$27.35 at Amazon](https://www.amazon.com.au/dp/B084Q16G8D?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Pro-Collagen Multi-Peptide Booster](https://lovi.care/skincare/au/p/paula-s-choice/pro-collagen-multi-peptide-booster/for/dry-skin) — Superior fit — [A$89.00 at Amazon](https://www.amazon.com.au/dp/B0BV3F1X4H?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [FANCL Facial Washing Powder](https://lovi.care/skincare/au/p/fancl/facial-washing-powder/for/dry-skin) — High fit — [A$35.50 at Amazon](https://www.amazon.com.au/dp/B01KTJXVI4?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Once a week
- Nourishing Mask: [MEDIHEAL Vita Essential Mask](https://lovi.care/skincare/au/p/mediheal/vita-essential-mask/for/dry-skin) — Superior fit — [A$28.48 at Amazon](https://www.amazon.com.au/dp/B09XWPL5VN?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Once a week

[Buy Medik8 routine · A$283.59 · 97% fit](https://www.amazon.com.au/gp/aws/cart/add.html?ASIN.1=B075Q18R92&Quantity.1=1&ASIN.2=B08Q6WZ6J1&Quantity.2=1&ASIN.3=B0BFQ9RD5B&Quantity.3=1&ASIN.4=B0GP9GJWTD&Quantity.4=1&ASIN.5=B084Q16G8D&Quantity.5=1&ASIN.6=B08FHWV9KD&Quantity.6=1&ASIN.7=B01KTJXVI4&Quantity.7=1&ASIN.8=B09XWPL5VN&Quantity.8=1&AssociateTag=lovi-care-web-routine-22) [Buy Paula's Choice routine · A$343.82 · 86% fit](https://www.amazon.com.au/gp/aws/cart/add.html?ASIN.1=B07R74CPPY&Quantity.1=1&ASIN.2=B00949CII0&Quantity.2=1&ASIN.3=B008EPPPDK&Quantity.3=1&ASIN.4=B0GP9GJWTD&Quantity.4=1&ASIN.5=B084Q16G8D&Quantity.5=1&ASIN.6=B0BV3F1X4H&Quantity.6=1&ASIN.7=B01KTJXVI4&Quantity.7=1&ASIN.8=B09XWPL5VN&Quantity.8=1&AssociateTag=lovi-care-web-routine-22) [See multi-brand routine · 97% fit](https://lovi.care/skincare/au/skin/dry-skin)

### Paula's Choice vs Medik8 routines for oily skin

#### Medik8-focused routine

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/au/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — [A$13.99 at Amazon](https://www.amazon.com.au/dp/B07C5SKVL7?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Some By Mi Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/au/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — [A$34.66 at Amazon](https://www.amazon.com.au/dp/B08125WDCF?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion (with Birch Sap)](https://lovi.care/skincare/au/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/oily-skin) — Superior fit — [A$22.99 at Amazon](https://www.amazon.com.au/dp/B01CLTKI4A?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [La Roche-Posay Anthelios Clear Skin Dry Touch Sunscreen SPF 60](https://lovi.care/skincare/au/p/la-roche-posay/anthelios-clear-skin-dry-touch-sunscreen-spf-60/for/oily-skin) — Superior fit — [A$27.99 at Amazon](https://www.amazon.com.au/dp/B017ROO5TS?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/au/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/oily-skin) — Superior fit — [A$80.43 at Amazon](https://www.amazon.com.au/dp/B0DNJKPSB8?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Caudalie Vinopure Purifying Toner](https://lovi.care/skincare/au/p/caudalie/vinopure-purifying-toner/for/oily-skin) — Superior fit — [A$75.95 at Amazon](https://www.amazon.com.au/dp/B0GFGP11BW?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [CRYSTAL RETINAL 3](https://lovi.care/skincare/au/p/medik8/crystal-retinal-3/for/oily-skin) — High fit — Evening · Once a week
- Enzyme Powder: [FANCL Facial Washing Powder](https://lovi.care/skincare/au/p/fancl/facial-washing-powder/for/oily-skin) — Superior fit — [A$35.50 at Amazon](https://www.amazon.com.au/dp/B01KTJXVI4?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask](https://lovi.care/skincare/au/p/herbivore-botanicals/blue-tansy-bha-and-enzyme-pore-refining-mask/for/oily-skin) — Superior fit — [A$118.35 at Amazon](https://www.amazon.com.au/dp/B015RRNQCY?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Once a week

#### Paula's Choice-focused routine

- Cleanser: [CLEAR Pore Normalizing Cleanser](https://lovi.care/skincare/au/p/paula-s-choice/clear-pore-normalizing-cleanser/for/oily-skin) — Superior fit — [A$32.00 at Amazon](https://www.amazon.com.au/dp/B07R74CPPY?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Advanced Replenishing Toner](https://lovi.care/skincare/au/p/paula-s-choice/advanced-replenishing-toner/for/oily-skin) — High fit — [A$42.00 at Amazon](https://www.amazon.com.au/dp/B00CJWACX2?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Clear Oil-Free Moisturizer](https://lovi.care/skincare/au/p/paula-s-choice/clear-oil-free-moisturizer/for/oily-skin) — High fit — [A$65.00 at Amazon](https://www.amazon.com.au/dp/B07HZWXGJ7?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [La Roche-Posay Anthelios Clear Skin Dry Touch Sunscreen SPF 60](https://lovi.care/skincare/au/p/la-roche-posay/anthelios-clear-skin-dry-touch-sunscreen-spf-60/for/oily-skin) — Superior fit — [A$27.99 at Amazon](https://www.amazon.com.au/dp/B017ROO5TS?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/au/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/oily-skin) — Superior fit — [A$80.43 at Amazon](https://www.amazon.com.au/dp/B0DNJKPSB8?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Caudalie Vinopure Purifying Toner](https://lovi.care/skincare/au/p/caudalie/vinopure-purifying-toner/for/oily-skin) — Superior fit — [A$75.95 at Amazon](https://www.amazon.com.au/dp/B0GFGP11BW?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Niacinamide 20% Treatment](https://lovi.care/skincare/au/p/paula-s-choice/niacinamide-20-treatment/for/oily-skin) — Superior fit — [A$84.00 at Amazon](https://www.amazon.com.au/dp/B083N1H6P7?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [FANCL Facial Washing Powder](https://lovi.care/skincare/au/p/fancl/facial-washing-powder/for/oily-skin) — Superior fit — [A$35.50 at Amazon](https://www.amazon.com.au/dp/B01KTJXVI4?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask](https://lovi.care/skincare/au/p/herbivore-botanicals/blue-tansy-bha-and-enzyme-pore-refining-mask/for/oily-skin) — Superior fit — [A$118.35 at Amazon](https://www.amazon.com.au/dp/B015RRNQCY?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Once a week

[Buy Medik8 routine · A$409.86 · 94% fit](https://www.amazon.com.au/gp/aws/cart/add.html?ASIN.1=B07C5SKVL7&Quantity.1=1&ASIN.2=B08125WDCF&Quantity.2=1&ASIN.3=B01CLTKI4A&Quantity.3=1&ASIN.4=B017ROO5TS&Quantity.4=1&ASIN.5=B0DNJKPSB8&Quantity.5=1&ASIN.6=B0GFGP11BW&Quantity.6=1&ASIN.7=B01KTJXVI4&Quantity.7=1&ASIN.8=B015RRNQCY&Quantity.8=1&AssociateTag=lovi-care-web-routine-22) [Buy Paula's Choice routine · A$561.22 · 92% fit](https://www.amazon.com.au/gp/aws/cart/add.html?ASIN.1=B07R74CPPY&Quantity.1=1&ASIN.2=B00CJWACX2&Quantity.2=1&ASIN.3=B07HZWXGJ7&Quantity.3=1&ASIN.4=B017ROO5TS&Quantity.4=1&ASIN.5=B0DNJKPSB8&Quantity.5=1&ASIN.6=B0GFGP11BW&Quantity.6=1&ASIN.7=B083N1H6P7&Quantity.7=1&ASIN.8=B01KTJXVI4&Quantity.8=1&ASIN.9=B015RRNQCY&Quantity.9=1&AssociateTag=lovi-care-web-routine-22) [See multi-brand routine · 96% fit](https://lovi.care/skincare/au/skin/oily-skin)

### Paula's Choice vs Medik8 routines for combination skin

#### Medik8-focused routine

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/au/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — [A$73.61 at Amazon](https://www.amazon.com.au/dp/B00AU9EBTC?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Paula's Choice Skin Balancing Pore-Reducing Toner](https://lovi.care/skincare/au/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — [A$42.00 at Amazon](https://www.amazon.com.au/dp/B008EPPIQ4?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion (with Birch Sap)](https://lovi.care/skincare/au/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — [A$22.99 at Amazon](https://www.amazon.com.au/dp/B01CLTKI4A?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Pre-Cleanser: [Pyunkang Yul Deep Cleansing Oil](https://lovi.care/skincare/au/p/pyunkang-yul/deep-cleansing-oil/for/combination-skin) — Superior fit — [A$30.99 at Amazon](https://www.amazon.com.au/dp/B08QTT1QBX?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Medicube Zero Pore Pad 2.0](https://lovi.care/skincare/au/p/medicube/zero-pore-pad-2-0/for/combination-skin) — Superior fit — [A$29.90 at Amazon](https://www.amazon.com.au/dp/B09V7Z4TJG?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Bakuchiol Peptides](https://lovi.care/skincare/au/p/medik8/bakuchiol-peptides/for/combination-skin) — High fit — [A$91.10 at Amazon](https://www.amazon.com.au/dp/B08FHWV9KD?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [FANCL Facial Washing Powder](https://lovi.care/skincare/au/p/fancl/facial-washing-powder/for/combination-skin) — Superior fit — [A$35.50 at Amazon](https://www.amazon.com.au/dp/B01KTJXVI4?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask](https://lovi.care/skincare/au/p/herbivore-botanicals/blue-tansy-bha-and-enzyme-pore-refining-mask/for/combination-skin) — Superior fit — [A$118.35 at Amazon](https://www.amazon.com.au/dp/B015RRNQCY?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Once a week

#### Paula's Choice-focused routine

- Cleanser: [CLEAR Pore Normalizing Cleanser](https://lovi.care/skincare/au/p/paula-s-choice/clear-pore-normalizing-cleanser/for/combination-skin) — Superior fit — [A$32.00 at Amazon](https://www.amazon.com.au/dp/B07R74CPPY?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Advanced Replenishing Toner](https://lovi.care/skincare/au/p/paula-s-choice/advanced-replenishing-toner/for/combination-skin) — High fit — [A$42.00 at Amazon](https://www.amazon.com.au/dp/B00CJWACX2?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Clear Oil-Free Moisturizer](https://lovi.care/skincare/au/p/paula-s-choice/clear-oil-free-moisturizer/for/combination-skin) — Average fit — [A$65.00 at Amazon](https://www.amazon.com.au/dp/B07HZWXGJ7?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Pre-Cleanser: [Pyunkang Yul Deep Cleansing Oil](https://lovi.care/skincare/au/p/pyunkang-yul/deep-cleansing-oil/for/combination-skin) — Superior fit — [A$30.99 at Amazon](https://www.amazon.com.au/dp/B08QTT1QBX?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Medicube Zero Pore Pad 2.0](https://lovi.care/skincare/au/p/medicube/zero-pore-pad-2-0/for/combination-skin) — Superior fit — [A$29.90 at Amazon](https://www.amazon.com.au/dp/B09V7Z4TJG?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Niacinamide 20% Treatment](https://lovi.care/skincare/au/p/paula-s-choice/niacinamide-20-treatment/for/combination-skin) — Superior fit — [A$84.00 at Amazon](https://www.amazon.com.au/dp/B083N1H6P7?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [FANCL Facial Washing Powder](https://lovi.care/skincare/au/p/fancl/facial-washing-powder/for/combination-skin) — Superior fit — [A$35.50 at Amazon](https://www.amazon.com.au/dp/B01KTJXVI4?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask](https://lovi.care/skincare/au/p/herbivore-botanicals/blue-tansy-bha-and-enzyme-pore-refining-mask/for/combination-skin) — Superior fit — [A$118.35 at Amazon](https://www.amazon.com.au/dp/B015RRNQCY?tag=lovi-care-web-routine-22&linkCode=osi&th=1&psc=1) — Once a week

[Buy Medik8 routine · A$444.44 · 93% fit](https://www.amazon.com.au/gp/aws/cart/add.html?ASIN.1=B00AU9EBTC&Quantity.1=1&ASIN.2=B008EPPIQ4&Quantity.2=1&ASIN.3=B01CLTKI4A&Quantity.3=1&ASIN.4=B08QTT1QBX&Quantity.4=1&ASIN.5=B09V7Z4TJG&Quantity.5=1&ASIN.6=B08FHWV9KD&Quantity.6=1&ASIN.7=B01KTJXVI4&Quantity.7=1&ASIN.8=B015RRNQCY&Quantity.8=1&AssociateTag=lovi-care-web-routine-22) [Buy Paula's Choice routine · A$437.74 · 89% fit](https://www.amazon.com.au/gp/aws/cart/add.html?ASIN.1=B07R74CPPY&Quantity.1=1&ASIN.2=B00CJWACX2&Quantity.2=1&ASIN.3=B07HZWXGJ7&Quantity.3=1&ASIN.4=B08QTT1QBX&Quantity.4=1&ASIN.5=B09V7Z4TJG&Quantity.5=1&ASIN.6=B083N1H6P7&Quantity.6=1&ASIN.7=B01KTJXVI4&Quantity.7=1&ASIN.8=B015RRNQCY&Quantity.8=1&AssociateTag=lovi-care-web-routine-22) [See multi-brand routine · 95% fit](https://lovi.care/skincare/au/skin/combination-skin)

## Questions and answers

### Paula's Choice or Medik8: which is better?

Paula's Choice and Medik8 both offer great options depending on your goals, with Paula's Choice providing a superior fit for texture and pores as well as acne and cleansing. Medik8 is frequently noted for gentle formulation, deep hydration, and plumping, and the products on this page achieve a superior routine fit for dry skin, combination skin, and skin with dark spots.

### What is the difference between Paula's Choice and Medik8?

Paula's Choice is better suited for texture, pores, acne, and cleansing, while Medik8 is often noted for gentle formulations and hydration. Paula's Choice features fragrance-free formulas across the products on this page, whereas Medik8 includes fragrance in select items like the Total Moisture Daily Facial Cream.

### Paula's Choice or Medik8 for dry skin?

Medik8 is a Superior fit for dry skin, whereas the products on this page from Paula's Choice achieve a High fit. Reviewers note that Medik8 helps provide deep hydration and plumping for dry skin types.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/) [Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/)

### Paula's Choice or Medik8: which cleanser is better?

Paula's Choice is better for acne and cleansing, with multiple cleansers rated as having a Superior fit for oily and acne-prone skin on the products on this page.

### Which is more affordable, Paula's Choice or Medik8?

Medik8 is often noted for a high price point among reviewers on this page, while Paula's Choice faces mentions of high price as well.

### Which brand has more fragrance-free products, Paula's Choice or Medik8?

Paula's Choice has more fragrance-free products, as every product on its page lists no fragrance in its ingredients. In contrast, Medik8 has 11 of 12 products listed as fragrance-free on this page, with its Total Moisture Daily Facial Cream containing fragrance.

### How do the founding years and corporate ownership of Paula's Choice and Medik8 compare?

Paula's Choice was founded in 1995 in the United States and has been owned by Unilever since 2021. Medik8 was founded in 2009 in the United Kingdom and is owned by L'Oréal Groupe.

### Which brand performs better for texture and pores based on review themes?

Paula's Choice performs better for texture and pores based on review themes.

### Paula's Choice or Medik8 for oily skin?

Both Paula's Choice and Medik8 achieve a Superior routine fit for oily skin. Paula's Choice features fragrance-free formulas with key ingredients like [salicylic acid](https://lovi.care/skincare/au/ingredients/salicylic-acid) and [niacinamide](https://lovi.care/skincare/au/ingredients/niacinamide).

### Paula's Choice or Medik8: which moisturizer is better?

Medik8 offers superior routine fit for dry skin compared to Paula's Choice, while both brands feature options with high fit for this skin type. Paula's Choice products on this page list no fragrance, whereas one Medik8 moisturizer includes fragrance.

### Paula's Choice or Medik8 for sensitive skin?

For sensitive skin, Paula's Choice is rated as a Superior fit, while Medik8 is also rated as a Superior fit on this page. Reviewers frequently note that Medik8 offers gentle and non-irritating formulas.

### Paula's Choice or Medik8 for acne-prone skin?

For acne-prone skin, Lovi finds that both Paula's Choice and Medik8 achieve a Superior routine fit. Paula's Choice features fragrance-free formulations with key ingredients like salicylic acid and [green tea](https://lovi.care/skincare/au/ingredients/green-tea) that help manage blemishes, while Medik8 provides gentle alternatives that are unlikely to irritate.

[The Journal of Investigative Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23096708/) [Carcinogenesis, 2001](https://pubmed.ncbi.nlm.nih.gov/11181450/)

## Research behind their key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage](https://pubmed.ncbi.nlm.nih.gov/28155509/) Hyaluronic acid · Drug Delivery, 2017
- [Green tea polyphenol (-)-epigallocatechin-3-gallate treatment of human skin inhibits ultraviolet radiation-induced oxidative stress](https://pubmed.ncbi.nlm.nih.gov/11181450/) Epigallocatechin gallate · Carcinogenesis, 2001
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Formation and stability of oil-in-water nanoemulsions containing rice bran oil: in vitro and in vivo assessments](https://pubmed.ncbi.nlm.nih.gov/21952107/) Rice bran oil · Journal of Nanobiotechnology, 2011
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Hyaluronic acid, Sodium hyaluronate · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [Epigallocatechin-3-gallate improves acne in humans by modulating intracellular molecular targets and inhibiting P. acnes](https://pubmed.ncbi.nlm.nih.gov/23096708/) Epigallocatechin gallate · The Journal of Investigative Dermatology, 2013
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Tocopherol vitamin e, Tocopherol, Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [A topical antioxidant solution containing vitamins C and E stabilized by ferulic acid provides protection for human skin against damage caused by ultraviolet irradiation](https://pubmed.ncbi.nlm.nih.gov/18603326/) Ferulic acid · Journal of the American Academy of Dermatology, 2008
- [Protective effects of a topical antioxidant mixture containing vitamin C, ferulic acid, and phloretin against ultraviolet-induced photodamage in human skin](https://pubmed.ncbi.nlm.nih.gov/19146606/) Ferulic acid · Journal of Cosmetic Dermatology, 2008
- [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017
- [Production and characterization of cosmetic nanoemulsions containing Opuntia ficus-indica (L.) mill extract as moisturizing agent](https://pubmed.ncbi.nlm.nih.gov/25648593/) Hydrolyzed opuntia ficus-indica flower extract · Molecules, 2015
- [Topical anti-inflammatory effects of isorhamnetin glycosides isolated from Opuntia ficus-indica](https://pubmed.ncbi.nlm.nih.gov/25821823/) Hydrolyzed opuntia ficus-indica flower extract · BioMed Research International, 2015
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Bakuchiol · The British Journal of Dermatology, 2019
- [Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo](https://pubmed.ncbi.nlm.nih.gov/19186973/) Ascorbyl glucoside · Journal of Periodontology, 2009
- [Skin-whitening and skin-condition-improving effects of topical oxidized glutathione: a double-blind and placebo-controlled clinical trial in healthy women](https://pubmed.ncbi.nlm.nih.gov/25378941/) Glutathione · Clinical, Cosmetic and Investigational Dermatology, 2014
- [Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo](https://pubmed.ncbi.nlm.nih.gov/27279007/) Chamomilla recutita flower extract matricaria flower extract · International Journal of Molecular Medicine, 2016
- [Topical delivery of tetrahydrocurcumin lipid nanoparticles effectively inhibits skin inflammation: in vitro and in vivo study](https://pubmed.ncbi.nlm.nih.gov/29938544/) Tetrahydrodiferuloylmethane · Drug Development and Industrial Pharmacy, 2018
- [Topical treatment with coenzyme Q10-containing formulas improves skin's Q10 level and provides antioxidative effects](https://pubmed.ncbi.nlm.nih.gov/26648450/) Ubiquinone · BioFactors, 2015
- [Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin](https://pubmed.ncbi.nlm.nih.gov/33037252/) Squalane · Scientific Reports, 2020
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice · Clinical Pharmacology, 2018
- [Urea: a comprehensive review of the clinical literature](https://pubmed.ncbi.nlm.nih.gov/24314769/) Urea · Dermatology Online Journal, 2013
- [A Double-Blind, Randomized Trial Shows the Role of Zonal Priming and Direct Topical Application of Epigallocatechin-3-Gallate in the Modulation of Cutaneous Scarring in Human Skin](https://pubmed.ncbi.nlm.nih.gov/30822414/) Epigallocatechin gallate · The Journal of Investigative Dermatology, 2019
- [Alteration of barrier properties, stratum corneum ceramides and microbiome composition in response to lotion application on cosmetic dry skin](https://pubmed.ncbi.nlm.nih.gov/35340018/) Ceramides · Scientific Reports, 2022
- [Topical benzoyl peroxide for acne](https://pubmed.ncbi.nlm.nih.gov/32175593/) Benzoyl peroxide · The Cochrane Database of Systematic Reviews, 2020
- [Effects of glyceryl glucoside on AQP3 expression, barrier function and hydration of human skin](https://pubmed.ncbi.nlm.nih.gov/22584263/) Glyceryl glucoside · Skin Pharmacology and Physiology, 2012
- [Antioxidant Opuntia ficus-indica Extract Activates AHR-NRF2 Signaling and Upregulates Filaggrin and Loricrin Expression in Human Keratinocytes](https://pubmed.ncbi.nlm.nih.gov/26061570/) Hydrolyzed opuntia ficus-indica flower extract · Journal of Medicinal Food, 2015
- [Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin](https://pubmed.ncbi.nlm.nih.gov/18717861/) Ceramide np · International Journal of Dermatology, 2008
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Tocopherol vitamin e, Ferulic acid · Journal of Cosmetic Dermatology, 2020
- [Licochalcone A activates Nrf2 in vitro and contributes to licorice extract-induced lowered cutaneous oxidative stress in vivo](https://pubmed.ncbi.nlm.nih.gov/25381913/) Licorice root extract, Glycyrrhiza glabra root extract licorice root extract · Experimental Dermatology, 2015
- [Tailoring of Retinyl Palmitate-Based Ethosomal Hydrogel as a Novel Nanoplatform for Acne Vulgaris Management: Fabrication, Optimization, and Clinical Evaluation Employing a Split-Face Comparative Study](https://pubmed.ncbi.nlm.nih.gov/34211271/) Retinyl palmitate · International Journal of Nanomedicine, 2021
- [Inhibitory effect of mulberroside A and its derivatives on melanogenesis induced by ultraviolet B irradiation](https://pubmed.ncbi.nlm.nih.gov/21946069/) Hydroxyresveratrol · Food and Chemical Toxicology, 2011
- [Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls](https://pubmed.ncbi.nlm.nih.gov/18631247/) Camellia oleifera leaf extract camellia sinensis leaf extract, Camellia sinensis leaf extract · Experimental Dermatology, 2009
- [Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/33923739/) Azelaic acid · Pharmaceutics, 2021
- [Clinical, biometric and structural evaluation of the long-term effects of a topical treatment with ascorbic acid and madecassoside in photoaged human skin](https://pubmed.ncbi.nlm.nih.gov/18503551/) Centella asiatica leaf extract · Experimental Dermatology, 2008
- [The clinical effect of glutathione on skin color and other related skin conditions: A systematic review](https://pubmed.ncbi.nlm.nih.gov/30895708/) Glutathione · Journal of Cosmetic Dermatology, 2019
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [Benzoyl peroxide treatment decreases Cutibacterium acnes in shoulder surgery, from skin incision until wound closure](https://pubmed.ncbi.nlm.nih.gov/33545336/) Benzoyl peroxide · Journal of Shoulder and Elbow Surgery, 2021
- [Reduction in the appearance of facial hyperpigmentation after use of moisturizers with a combination of topical niacinamide and N-acetyl glucosamine: results of a randomized, double-blind, vehicle-controlled trial](https://pubmed.ncbi.nlm.nih.gov/19845667/) Acetyl glucosamine · The British Journal of Dermatology, 2010
- [Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine](https://pubmed.ncbi.nlm.nih.gov/17348991/) Acetyl glucosamine · Journal of Cosmetic Dermatology, 2007
- [Efficacy and Safety of a Fixed-Dose Clindamycin Phosphate 1.2%, Benzoyl Peroxide 3.1%, and Adapalene 0.15% Gel for Moderate-to-Severe Acne: A Randomized Phase II Study of the First Triple-Combination Drug](https://pubmed.ncbi.nlm.nih.gov/34674160/) Benzoyl peroxide · American Journal of Clinical Dermatology, 2022
- [A randomized, controlled comparative study of the wrinkle reduction benefits of a cosmetic niacinamide/peptide/retinyl propionate product regimen vs. a prescription 0.02% tretinoin product regimen](https://pubmed.ncbi.nlm.nih.gov/20374604/) Retinyl propionate · The British Journal of Dermatology, 2010
- [The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/23417317/) Acetyl hexapeptide-8 · American Journal of Clinical Dermatology, 2013
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [Adenosine-loaded dissolving microneedle patches to improve skin wrinkles, dermal density, elasticity and hydration](https://pubmed.ncbi.nlm.nih.gov/29574973/) Adenosine · International Journal of Cosmetic Science, 2018
- [Comparative study of efficacy and safety of 45% mandelic acid versus 30% salicylic acid peels in mild-to-moderate acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/31553119/) Mandelic acid · Journal of Cosmetic Dermatology, 2020
- [Treatment of xerosis with a topical formulation containing glyceryl glucoside, natural moisturizing factors, and ceramide](https://pubmed.ncbi.nlm.nih.gov/22916312/) Moisturizing factors nmf, Glyceryl glucoside · The Journal of Clinical and Aesthetic Dermatology, 2012
- [Clinical evidence of the efficacy and safety of a new 3-in-1 anti-aging topical night serum-in-oil containing melatonin, bakuchiol, and ascorbyl tetraisopalmitate: 103 females treated from 28 to 84 days](https://pubmed.ncbi.nlm.nih.gov/30924254/) Tetrahexyldecyl ascorbate · Journal of Cosmetic Dermatology, 2019
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Allantoin, Panthenol · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [Sunscreens and Cosmetic Formulations Containing Ascorbyl Tetraisopalmitate and Rice Peptides for the Improvement of Skin Photoaging: A Double-blind, Randomized Placebo-controlled Clinical Study](https://pubmed.ncbi.nlm.nih.gov/33529350/) Tetrahexyldecyl ascorbate · Photochemistry and Photobiology, 2021
- [Topical glutathione amino acid precursors protect skin against environmental and oxidative stress](https://pubmed.ncbi.nlm.nih.gov/38189670/) Glutathione · Journal of the European Academy of Dermatology and Venereology, 2024
- [An Open-Label Single-Arm, Monocentric Study Assessing the Efficacy and Safety of Natural Pterostilbene (Pterocarpus marsupium) for Skin Brightening and Antiaging Effects](https://pubmed.ncbi.nlm.nih.gov/32099438/) Blueberry fruit extract · Clinical, Cosmetic and Investigational Dermatology, 2020
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Gluconolactone, Glycolic acid · Clinical, Cosmetic and Investigational Dermatology, 2019
- [In vivo skin irritation potential of a Castanea sativa (Chestnut) leaf extract, a putative natural antioxidant for topical application](https://pubmed.ncbi.nlm.nih.gov/18793273/) Chestnut leaf extract · Basic & Clinical Pharmacology & Toxicology, 2008
- [Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin](https://pubmed.ncbi.nlm.nih.gov/33911590/) Acetyl hexapeptide-8 · Annals of Dermatology, 2019
- [Systematic Study of Paeonol/Madecassoside Co-Delivery Nanoemulsion Transdermal Delivery System for Enhancing Barrier Repair and Anti-Inflammatory Efficacy](https://pubmed.ncbi.nlm.nih.gov/37446936/) Centella asiatica leaf extract · Molecules, 2023
- [A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne](https://pubmed.ncbi.nlm.nih.gov/1303072/) Gluconolactone · The Australasian Journal of Dermatology, 1992
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [Clinical evaluation of photoprotective effect by a topical antioxidants combination (tocopherols and tocotrienols)](https://pubmed.ncbi.nlm.nih.gov/21917024/) Tocotrienols · Journal of the European Academy of Dermatology and Venereology, 2012
- [Tocotrienol-rich fraction attenuates UV-induced inflammaging: A bench to bedside study](https://pubmed.ncbi.nlm.nih.gov/28952200/) Tocotrienols · Journal of Cosmetic Dermatology, 2018
- [Fatty acids based α-Tocopherol loaded nanostructured lipid carrier gel: In vitro and in vivo evaluation for moisturizing and anti-aging effects](https://pubmed.ncbi.nlm.nih.gov/32129554/) Vitamin e · Journal of Cosmetic Dermatology, 2020
- [A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid](https://pubmed.ncbi.nlm.nih.gov/34348350/) Ceramide np · Skin Pharmacology and Physiology, 2022
- [Comparison of clinical efficacies of sodium ascorbyl phosphate, retinol and their combination in acne treatment](https://pubmed.ncbi.nlm.nih.gov/19134126/) Sodium ascorbyl phosphate · International Journal of Cosmetic Science, 2009
- [Efficacy and Tolerability of a Skin Brightening/Anti-Aging Cosmeceutical Containing Retinol 0.5%, Niacinamide, Hexylresorcinol, and Resveratrol](https://pubmed.ncbi.nlm.nih.gov/27391637/) Hexylresorcinol · Journal of Drugs in Dermatology, 2016
- [Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications](https://pubmed.ncbi.nlm.nih.gov/25817264/) Palmitoyl tetrapeptide-7 · Journal of Cosmetic Dermatology, 2015
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Antioxidant-based topical formulations influence on the inflammatory response of Japanese skin: A clinical study using non-invasive techniques](https://pubmed.ncbi.nlm.nih.gov/28385617/) Tetrahexyldecyl ascorbate · European Journal of Pharmaceutics and Biopharmaceutics, 2017
- [Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/38734843/) Azelaic acid · Dermatology and Therapy, 2024
- [Efficacy and safety of microencapsulated benzoyl peroxide and microencapsulated tretinoin for the treatment of acne vulgaris: Results from two phase 3 double-blind, randomized, vehicle-controlled studies](https://pubmed.ncbi.nlm.nih.gov/37356627/) Benzoyl peroxide · Journal of the American Academy of Dermatology, 2023
- [A dermocosmetic containing bakuchiol, Ginkgo biloba extract and mannitol improves the efficacy of adapalene in patients with acne vulgaris: result from a controlled randomized trial](https://pubmed.ncbi.nlm.nih.gov/25914553/) Bakuchiol · Clinical, Cosmetic and Investigational Dermatology, 2015
- [Efficacy of a topical serum containing L-ascorbic acid, neohesperidin, pycnogenol, tocopherol, and hyaluronic acid in relation to skin aging signs](https://pubmed.ncbi.nlm.nih.gov/35150043/) Vitamin e · Journal of Cosmetic Dermatology, 2022
- [Superior even skin tone and anti-ageing benefit of a combination of 4-hexylresorcinol and niacinamide](https://pubmed.ncbi.nlm.nih.gov/34958693/) Hexylresorcinol · International Journal of Cosmetic Science, 2022
- [Chemical peels for acne vulgaris: a systematic review of randomised controlled trials](https://pubmed.ncbi.nlm.nih.gov/29705755/) Mandelic acid · BMJ Open, 2018
- [Efficacy and safety of moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese versus 0.02% triamcinolone acetonide cream in decreasing adverse reaction and downtime after ablative fractional carbon dioxide laser resurfacing: A split-face, double-blinded, randomized, controlled trial](https://pubmed.ncbi.nlm.nih.gov/30945430/) Centella asiatica leaf extract · Journal of Cosmetic Dermatology, 2019
- [Retaining Skin Barrier Function Properties of the Stratum Corneum with Components of the Natural Moisturizing Factor-A Randomized, Placebo-Controlled Double-Blind In Vivo Study](https://pubmed.ncbi.nlm.nih.gov/33809557/) Moisturizing factors nmf · Molecules, 2021
- [Development of stable tocopherol succinate-loaded ethosomes to enhance transdermal permeation: In vitro and in vivo characterizations](https://pubmed.ncbi.nlm.nih.gov/35274433/) Vitamin e · Journal of Cosmetic Dermatology, 2022
- [Stretchable skin hydrating PVB patches with controlled pores' size and shape for deliberate evening primrose oil spreading, transport and release](https://pubmed.ncbi.nlm.nih.gov/35929319/) Oenothera biennis oil · Biomaterials Advances, 2022
- [Topical application of jojoba (Simmondsia chinensis L.) wax enhances the synthesis of pro-collagen III and hyaluronic acid and reduces inflammation in the ex-vivo human skin organ culture model](https://pubmed.ncbi.nlm.nih.gov/38344180/) Jojoba seed oil · Frontiers in Pharmacology, 2024
- [Antiacne and antiblotch activities of a formulated combination of Aloe barbadensis leaf powder, Garcinia mangostana peel extract, and Camellia sinensis leaf extract](https://pubmed.ncbi.nlm.nih.gov/31239743/) Camellia oleifera leaf extract camellia sinensis leaf extract, Camellia sinensis leaf extract · Clinical, Cosmetic and Investigational Dermatology, 2019
- [The usefulness of a dermocosmetic containing Myrtus communis extract and azelaic acid for maintenance phase of adult female acne: Results from a randomized exploratory investigator-blinded comparative study](https://pubmed.ncbi.nlm.nih.gov/36729399/) Azelaic acid · Journal of the European Academy of Dermatology and Venereology, 2023
- [Whitening effect of alpha-bisabolol in Asian women subjects](https://pubmed.ncbi.nlm.nih.gov/20642768/) Bisabolol · International Journal of Cosmetic Science, 2010
- [Is benzyl alcohol a significant contact sensitizer?](https://pubmed.ncbi.nlm.nih.gov/35080274/) Benzyl alcohol · Journal of the European Academy of Dermatology and Venereology, 2022
- [Evaluation of moisturizing and irritation potential of sacha inchi oil](https://pubmed.ncbi.nlm.nih.gov/31441999/) Plukenetia volubilis seed oil · Journal of Cosmetic Dermatology, 2020
- [Inhibitory effects of shell of Camellia oleifera Abel extract on mushroom tyrosinase and human skin melanin](https://pubmed.ncbi.nlm.nih.gov/31033161/) Butylene glycol · Journal of Cosmetic Dermatology, 2019
- [Effect of a botanical cleansing lotion on skin sebum and erythema of the face: A randomized controlled blinded half-side comparison](https://pubmed.ncbi.nlm.nih.gov/30022595/) Willow bark extract · Journal of Cosmetic Dermatology, 2019
- [Anti-Inflammatory Effect of a Novel Topical Herbal Composition (VEL-091604) Consisting of Gentian Root, Licorice Root and Willow Bark Extract](https://pubmed.ncbi.nlm.nih.gov/30690691/) Willow bark extract · Planta Medica, 2019
- [Apple Extract (Malus sp.) and Rutin as Photochemopreventive Agents: Evaluation of Ultraviolet B-Induced Alterations on Skin Biopsies and Tissue-Engineered Skin](https://pubmed.ncbi.nlm.nih.gov/32242497/) Pyrus malus fruit extract · Rejuvenation Research, 2020
- [Administration of skin care regimens containing β-glucan for skin recovery after fractional laser therapy: A split-face, double-blinded, vehicle-controlled study](https://pubmed.ncbi.nlm.nih.gov/33128496/) Beta-glucan · Journal of Cosmetic Dermatology, 2021
- [Assessment of Combined Ascorbyl Palmitate (AP) and Sodium Ascorbyl Phosphate (SAP) on Facial Skin Sebum Control in Female Healthy Volunteers](https://pubmed.ncbi.nlm.nih.gov/27756097/) Sodium ascorbyl phosphate · Drug Research, 2017
- [A randomized, double-blind, vehicle-controlled study of a preparation containing undecylenoyl phenylalanine 2% in the treatment of solar lentigines](https://pubmed.ncbi.nlm.nih.gov/19874316/) Undecylenoyl phenylalanine · Clinical and Experimental Dermatology, 2010
- [Two-phase delivery using a horse oil and adenosine-loaded dissolving microneedle patch for skin barrier restoration, moisturization, and wrinkle improvement](https://pubmed.ncbi.nlm.nih.gov/30160014/) Adenosine · Journal of Cosmetic Dermatology, 2019
- [The impacts of sodium lauroyl sarcosinate in facial cleanser on facial skin microbiome and lipidome](https://pubmed.ncbi.nlm.nih.gov/37990616/) Sodium lauroyl sarcosinate · Journal of Cosmetic Dermatology, 2024
- [Nanostructured Lipid Carrier for Topical Application of N-Acetyl Glucosamine](https://pubmed.ncbi.nlm.nih.gov/28101465/) Acetyl glucosamine · Advanced Pharmaceutical Bulletin, 2016
- [Repair of acetone- and sodium lauryl sulphate-damaged human skin barrier function using topically applied emulsions containing barrier lipids](https://pubmed.ncbi.nlm.nih.gov/12482041/) Phytosphingosine · Journal of the European Academy of Dermatology and Venereology, 2002
- [Stability, antioxidant activity, in vivo safety and efficacy of creams with standardized wild apple fruit extract: a comparison of conventional and biodegradable emulsifiers](https://pubmed.ncbi.nlm.nih.gov/31050807/) Pyrus malus fruit extract · International Journal of Cosmetic Science, 2019
- [Borage Oil Treated with Immobilized Lipase Inhibits Melanogenesis](https://pubmed.ncbi.nlm.nih.gov/33128473/) Borago officinalis oil, Borago officinalis seed oil · Lipids, 2020
- [Development, Characterization, and Clinical Investigation of a New Topical Emulsion System Containing a Castanea sativa Spiny Burs Active Extract](https://pubmed.ncbi.nlm.nih.gov/34683927/) Chestnut leaf extract · Pharmaceutics, 2021
- [Development of solid lipid microparticles (SLMs) containing asiatic acid for topical treatment of acne: Characterization, stability, in vitro and in vivo anti-acne assessment](https://pubmed.ncbi.nlm.nih.gov/38460769/) Centella asiatica leaf extract · International Journal of Pharmaceutics, 2024
- [Synergetic Effects of Aloe Vera Extract with Trimethylglycine for Targeted Aquaporin 3 Regulation and Long-Term Skin Hydration](https://pubmed.ncbi.nlm.nih.gov/38611819/) Aloe barbadensis flower extract · Molecules, 2024
- [Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast](https://pubmed.ncbi.nlm.nih.gov/40363772/) Squalane · Molecules, 2025
- [Clinical Development and Evaluation of a Multi-Component Dissolving Microneedle Patch for Skin Pigmentation Disorders](https://pubmed.ncbi.nlm.nih.gov/37571190/) 3-o-ethyl ascorbic acid · Polymers, 2023
- [Fractional microneedle radiofrequency with the application of vitamin C, E, and ferulic acid serum for neck skin rejuvenation: a prospective, double-blinded, split-neck, placebo-controlled trial](https://pubmed.ncbi.nlm.nih.gov/40464749/) Ferulic acid · The Journal of Dermatological Treatment, 2025
- [Supramolecular collagen nanoparticles for anti-wrinkle, skin whitening, and moisturizing effects](https://pubmed.ncbi.nlm.nih.gov/39383579/) Palmitoyl tripeptide-5 · Colloids and Surfaces. B, Biointerfaces, 2025
- [Effects of Investigational Moisturizers on the Skin Barrier and Microbiome following Exposure to Environmental Aggressors: A Randomized Clinical Trial and Ex Vivo Analysis](https://pubmed.ncbi.nlm.nih.gov/37763018/) Hydrolyzed yeast extract · Journal of Clinical Medicine, 2023
- [Epigallocatechin Gallate Enzymatic Alpha Glucosylation Potentiates Its Skin-Lightening Activity-Involvement of Skin Microbiota](https://pubmed.ncbi.nlm.nih.gov/39598779/) Camellia oleifera leaf extract camellia sinensis leaf extract · Molecules, 2024
- [Novel beads made of alpha-cyclodextrin and oil for topical delivery of a lipophilic drug](https://pubmed.ncbi.nlm.nih.gov/17671830/) Glycine soja oil soybean oil · Pharmaceutical Research, 2008
- [Randomized prospective study of low-dose isotretinoin alone and combination with salicylic acid and mandelic peel against acne tarda](https://pubmed.ncbi.nlm.nih.gov/35388606/) Mandelic acid · Journal of Cosmetic Dermatology, 2022
- [Depth-dependent hydration dynamics in human skin: Vehicle-controlled efficacy assessment of a functional 10% urea plus NMF moisturizer by near-infrared confocal spectroscopic imaging (KOSIM IR) and capacitance method complemented by volunteer perception](https://pubmed.ncbi.nlm.nih.gov/35034387/) Moisturizing factors nmf · Skin Research and Technology, 2022
- [Effect of hydroxypropyl-β-cyclodextrin in fluid and semi-solid submicron emulsions on physiological skin parameters during regular in vivo application](https://pubmed.ncbi.nlm.nih.gov/33236374/) Cyclodextrin · International Journal of Cosmetic Science, 2021
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Emulgels Containing Perilla frutescens Seed Oil, Moringa oleifera Seed Oil, and Mixed Seed Oil: Microemulsion and Safety Assessment](https://pubmed.ncbi.nlm.nih.gov/35745923/) Moringa oleifera seed oil · Polymers, 2022
- [Assessment of the efficacy and safety of a new complex skin cream in Asian women: A controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/28512843/) Hydroxyresveratrol · Journal of Cosmetic Dermatology, 2017
- [A randomized controlled trial to compare the effectiveness and safety of adsorbent lotion containing tapioca starch, spent grain wax, Butyrospermum parkii extract, argania spinosa kernel oil, aloe barbadensis, rosehip oil, and allantoin with a low-potency topical corticosteroid in the treatment of intertrigo](https://pubmed.ncbi.nlm.nih.gov/33811776/) Shea butter · Journal of Cosmetic Dermatology, 2022
- [Lactobionic acid in a natural alkylpolyglucoside-based vehicle: assessing safety and efficacy aspects in comparison to glycolic acid](https://pubmed.ncbi.nlm.nih.gov/20367666/) Pha polyhydroxy acid · Journal of Cosmetic Dermatology, 2010
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025
- [Standardized wild apple fruit extract as a bioactive agent in dermocosmetic products for efficacy skin hydration-In vitro and in vivo evaluation](https://pubmed.ncbi.nlm.nih.gov/35048513/) Pyrus malus fruit extract · Journal of Cosmetic Dermatology, 2022
- [Tocopherol succinate-loaded ethosomal gel synthesized by cold method technique: Deeper biophysical characterizations for translational application on human skin](https://pubmed.ncbi.nlm.nih.gov/38268219/) Vitamin e · Journal of Cosmetic Dermatology, 2024
- [The effect of a vitamin A palmitate and antioxidant-containing oil-based moisturizer on photodamaged skin of several body sites](https://pubmed.ncbi.nlm.nih.gov/23438139/) Retinyl palmitate · Journal of Cosmetic Dermatology, 2013
- [TiO2-embedded mesoporous silica with lower porosity is beneficial to adsorb the pollutants and retard UV filter absorption: A possible application for outdoor skin protection](https://pubmed.ncbi.nlm.nih.gov/36455708/) Avobenzone · European Journal of Pharmaceutical Sciences, 2023
- [Prospective, randomized, double-blind clinical study of split-body comparison of topical hydroquinone and hexylresorcinol for skin pigment appearance](https://pubmed.ncbi.nlm.nih.gov/36502500/) Hexylresorcinol · Archives of Dermatological Research, 2023
- [The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects](https://pubmed.ncbi.nlm.nih.gov/23607739/) Acetyl hexapeptide-8 · Journal of Cosmetic and Laser Therapy, 2013
- [Prospective randomized double-blind comparative study of topical acetyl zingerone with tetrahexyldecyl ascorbate versus tetrahexyldecyl ascorbate alone on facial photoaging](https://pubmed.ncbi.nlm.nih.gov/38525606/) Tetrahexyldecyl ascorbate · Journal of Cosmetic Dermatology, 2024
- [Translational Evaluation of a Disodium Adenosine Monophosphate (AMP2Na)-Based Topical Formulation for Physiology-Aligned Skin Rejuvenation: Integrated In Vitro, Ex Vivo, and Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/42278371/) Adenosine · International Journal of Molecular Sciences, 2026
- [Functional properties and skin care effects of sodium trehalose sulfate](https://pubmed.ncbi.nlm.nih.gov/38606717/) Trehalose · Skin Research and Technology, 2024
- [A Double-Blind, 12-Week Study to Evaluate the Antiaging Efficacy of a Cream Containing the NFκB Inhibitor 4-Hexyl-1, 3-Phenylenediol and Ascorbic Acid-2 Glucoside in Adult Females](https://pubmed.ncbi.nlm.nih.gov/27272084/) Ascorbyl glucoside · Journal of Drugs in Dermatology, 2016
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Improving the outcome of treating striae gravidarum by combined therapies using topical β-glucan and 1565-nm non-ablative fractional laser: A prospective randomized vehicle-controlled parallel group study](https://pubmed.ncbi.nlm.nih.gov/35570397/) Beta-glucan · The Journal of Dermatology, 2022
- [Treatment of Stretch Marks Using a New Formulation Combining Nanofractional Radiofrequency Plus Magnetic Nanofractional Radiofrequency](https://pubmed.ncbi.nlm.nih.gov/37171578/) Beta-glucan · Dermatology and Therapy, 2023
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Noninvasive Monitoring of Palmitoyl Hexapeptide-12 in Human Skin Layers: Mechanical Interaction with Skin Components and Its Potential Skincare Benefits](https://pubmed.ncbi.nlm.nih.gov/39964201/) Palmitoyl hexapeptide-12 · ACS Applied Bio Materials, 2025
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate, Tocopheryl acetate vitamin e · Contemporary Clinical Trials Communications, 2021
- [Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos](https://pubmed.ncbi.nlm.nih.gov/39769217/) Ascorbyl glucoside · International Journal of Molecular Sciences, 2024
- [A Randomized Controlled Trial of the Genistein Plus Bakuchiol and Vitamins (GEN+) Product for Male Facial Skin: Effects on Skin Appearance and Properties](https://pubmed.ncbi.nlm.nih.gov/41562471/) Bakuchiol · Skin Research and Technology, 2026
- [Facial disbiosis and UV filters](https://pubmed.ncbi.nlm.nih.gov/39499337/) Octinoxate · Archives of Dermatological Research, 2024
- [Portulaca oleracea extract relieves skin barrier damage induced by increased photosensitivity after GA peeling](https://pubmed.ncbi.nlm.nih.gov/35920724/) Portulaca oleracea extract purslane extract · Cutaneous and Ocular Toxicology, 2022
- [Topical application of retinyl propionate, 4 hexyl resorcinol, and niacinamide reverses molecular and clinical features of ageing](https://pubmed.ncbi.nlm.nih.gov/38685700/) Retinyl propionate · International Journal of Cosmetic Science, 2024
- [Retinyl propionate and climbazole combination demonstrates clinical improvement to the appearance of hyperpigmentation and deep wrinkling with minimal irritation](https://pubmed.ncbi.nlm.nih.gov/28733999/) Retinyl propionate · International Journal of Cosmetic Science, 2017
- [A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimen](https://pubmed.ncbi.nlm.nih.gov/15002657/) Pha polyhydroxy acid · Cutis, 2004
- [Efficacy of a Topical Formulation on Skin Hydration and Barrier Function in Individuals With Xerosis: A 28-Day Randomized, Split-Leg, Untreated-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42108609/) Dipotassium glycyrrhizate · Journal of Cosmetic Dermatology, 2026
- [Impact of dermal emulsions containing diacyl phospholipids, mono acyl phospholipids, sodium lauryl ether sulfate and polysorbate 80 in combination with UVA irradiation on human skin physiology in vivo: A pilot study](https://pubmed.ncbi.nlm.nih.gov/42617898/) Sodium laureth sulfate · International Journal of Pharmaceutics, 2026
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Shea butter · Lasers in Medical Science, 2025
- [Prospective, Randomized, Double-Blind Assessment of Supramolecular Bakuchiol and Terminalia Chebula Extract for Facial Photoaging in Chinese Sensitive Skin Population](https://pubmed.ncbi.nlm.nih.gov/41424674/) Bakuchiol · Health Science Reports, 2025
- [Low-temperature extracted Portulaca oleracea L. as a functional ingredient in facial masks for photorejuvenation of sensitive skin](https://pubmed.ncbi.nlm.nih.gov/41182319/) Portulaca oleracea extract purslane extract · Cutaneous and Ocular Toxicology, 2025
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026
- [A novel facial moisturizer containing Saccharide isomerate accelerates skin barrier restoration following intense pulsed light treatment: a randomized split-face study](https://pubmed.ncbi.nlm.nih.gov/41211697/) Saccharide isomerate · The Journal of Dermatological Treatment, 2025
- [Split-face evaluation: Gluconolactone plus oxybrasion versus gluconolactone plus microneedling. The effects on skin parameters](https://pubmed.ncbi.nlm.nih.gov/37357656/) Gluconolactone · Skin Research and Technology, 2023
- [Preclinical Safety Evaluation of Dual Drug-Loaded Nanolipidic Carriers of Dissolvable Patches: In-Vitro and In-Vivo Safety Assessment](https://pubmed.ncbi.nlm.nih.gov/41186117/) Tetrahydrodiferuloylmethane · Molecular Pharmaceutics, 2025
- [Acai Oil-Based Organogel Containing Hyaluronic Acid for Topical Cosmetic: In Vitro and Ex Vivo Assessment](https://pubmed.ncbi.nlm.nih.gov/39339231/) Euterpe oleracea fruit extract · Pharmaceutics, 2024

## The brands

- American skincare: [Paula's Choice](https://lovi.care/skincare/au/brands/paula-s-choice)
- British skincare: [Medik8](https://lovi.care/skincare/au/brands/medik8)

## More comparisons

- [SKIN1004 vs Paula's Choice](https://lovi.care/skincare/au/compare/skin1004-vs-paula-s-choice)
- [SKIN1004 vs Medik8](https://lovi.care/skincare/au/compare/skin1004-vs-medik8)
- [Anua vs Paula's Choice](https://lovi.care/skincare/au/compare/anua-vs-paula-s-choice)
- [Anua vs Medik8](https://lovi.care/skincare/au/compare/anua-vs-medik8)
- [Medicube vs Paula's Choice](https://lovi.care/skincare/au/compare/medicube-vs-paula-s-choice)
- [Medicube vs Medik8](https://lovi.care/skincare/au/compare/medicube-vs-medik8)
- [The Ordinary vs Paula's Choice](https://lovi.care/skincare/au/compare/the-ordinary-vs-paula-s-choice)
- [The Ordinary vs Medik8](https://lovi.care/skincare/au/compare/the-ordinary-vs-medik8)
- [Beauty of Joseon vs Paula's Choice](https://lovi.care/skincare/au/compare/beauty-of-joseon-vs-paula-s-choice)
- [Beauty of Joseon vs Medik8](https://lovi.care/skincare/au/compare/beauty-of-joseon-vs-medik8)
- [COSRX vs Paula's Choice](https://lovi.care/skincare/au/compare/cosrx-vs-paula-s-choice)
- [COSRX vs Medik8](https://lovi.care/skincare/au/compare/cosrx-vs-medik8)
- [CeraVe vs Paula's Choice](https://lovi.care/skincare/au/compare/cerave-vs-paula-s-choice)
- [CeraVe vs Medik8](https://lovi.care/skincare/au/compare/cerave-vs-medik8)
- [La Roche-Posay vs Paula's Choice](https://lovi.care/skincare/au/compare/la-roche-posay-vs-paula-s-choice)
- [La Roche-Posay vs Medik8](https://lovi.care/skincare/au/compare/la-roche-posay-vs-medik8)
- [Dr. Althea vs Paula's Choice](https://lovi.care/skincare/au/compare/dr-althea-vs-paula-s-choice)
- [Dr. Althea vs Medik8](https://lovi.care/skincare/au/compare/dr-althea-vs-medik8)
- [Some By Mi vs Paula's Choice](https://lovi.care/skincare/au/compare/some-by-mi-vs-paula-s-choice)
- [Some By Mi vs Medik8](https://lovi.care/skincare/au/compare/some-by-mi-vs-medik8)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/paula-s-choice-vs-medik8
- United Kingdom: https://lovi.care/skincare/uk/compare/paula-s-choice-vs-medik8
- Ireland: https://lovi.care/skincare/ie/compare/paula-s-choice-vs-medik8
- Germany: https://lovi.care/skincare/de/compare/paula-s-choice-vs-medik8
- France: https://lovi.care/skincare/fr/compare/paula-s-choice-vs-medik8
- Italy: https://lovi.care/skincare/it/compare/paula-s-choice-vs-medik8
- Netherlands: https://lovi.care/skincare/nl/compare/paula-s-choice-vs-medik8
- Spain: https://lovi.care/skincare/es/compare/paula-s-choice-vs-medik8
- Canada: https://lovi.care/skincare/ca/compare/paula-s-choice-vs-medik8
- Australia: https://lovi.care/skincare/au/compare/paula-s-choice-vs-medik8 (this page)
- Singapore: https://lovi.care/skincare/sg/compare/paula-s-choice-vs-medik8
- Saudi Arabia: https://lovi.care/skincare/sa/compare/paula-s-choice-vs-medik8
- United Arab Emirates: https://lovi.care/skincare/ae/compare/paula-s-choice-vs-medik8