# ISDIN vs Theramid

Page: https://lovi.care/skincare/au/compare/isdin-vs-theramid

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Australia.

ISDIN and Theramid are two Spanish skincare brands that offer sophisticated moisturizers, advanced sunscreens, targeted [serums](https://lovi.care/skincare/au/ingredients/serum), and soothing eye products. The first brand is known for gentle yet effective compositions that suit sensitive and oily acne-prone skin best, while the second brand provides thoughtful compositions suitable for balanced, dry, combination, oily, and sensitive skin. They differ primarily in their founding years, ownership, and specific standout options like Fusion [Water](https://lovi.care/skincare/au/ingredients/water) or Ceramide Treatment, but both deliver meticulously engineered formulas to help users achieve a balanced, radiant complexion.

ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.

[puig.com](https://www.puig.com/en/newsroom/new-chapter-for-Isdin-Puig-to-assume-full-ownership/) [beautymatter.com](https://beautymatter.com/articles/puig-to-take-full-ownership-of-isdin-in-1-39-billion-deal) [uploads.puig.com](https://uploads.puig.com/uploads/Puig_NP_Sept_14_EN_fc21e2f47a.pdf)

Theramid is a Spanish skincare brand founded in 2022 and owned by Cosnova Group since 2026.

[cosmeticsbusiness.com](https://cosmeticsbusiness.com/cosnova-acquires-niche-beauty-labs-expand-skin-care)

This page compares some of the most popular ISDIN and Theramid products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg91d892a5a6).

### Popular ISDIN vs Theramid products

#### Theramid

- [Copper Peptide](https://lovi.care/skincare/au/p/theramid/copper-peptide/for/oily-skin) — High fit
- [DERMA-PEPTIDES](https://lovi.care/skincare/au/p/theramid/derma-peptides/for/mature-skin) — High fit
- [Ceramide Treatment](https://lovi.care/skincare/au/p/theramid/ceramide-treatment/for/dry-sensitive-skin) — Superior fit

#### ISDIN

- [Eryfotona Actinica](https://lovi.care/skincare/au/p/isdin/eryfotona-actinica/for/mature-skin) — Superior fit
- [Fusion Water](https://lovi.care/skincare/au/p/isdin/fusion-water/for/dry-sensitive-skin) — Superior fit
- [K-Ox Eyes](https://lovi.care/skincare/au/p/isdin/k-ox-eyes/for/dry-skin) — High fit
- [Hyaluronic Concentrate](https://lovi.care/skincare/au/p/isdin/hyaluronic-concentrate/for/sensitive-skin) — High fit
- [Hyaluronic Moisture](https://lovi.care/skincare/au/p/isdin/hyaluronic-moisture/for/dry-sensitive-skin) — Average fit
- [Flavo-C Serum](https://lovi.care/skincare/au/p/isdin/flavo-c-serum/for/sensitive-skin) — High fit — [A$30.99 at Amazon](https://www.amazon.com.au/dp/B0947C56TC?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
- [Uradin Lotion 10](https://lovi.care/skincare/au/p/isdin/uradin-lotion-10/for/dry-skin) — High fit
- [Retinal Intense Serum](https://lovi.care/skincare/au/p/isdin/retinal-intense-serum/for/acne-prone-skin) — High fit

## People Say

ISDIN

Theramid

- Lightweight and Fast-Absorbing Texture Mostly Mentioned Mostly Mentioned “absorbs instantly — ISDIN Eryfotona Actinica” “ultra-light fluid product, which makes it super easy to apply — ISDIN Fusion Water” “the texture is a sophisticated, lightweight gel that absorbs almost instantly without leaving a sticky residue — Theramid Copper Peptide” “Absorbs quickly — Theramid DERMA-PEPTIDES”
- Gentle on Sensitive Skin and Non-Irritating Often Mentioned Often Mentioned “Sensitive/reactive skin tolerates — ISDIN Hyaluronic Moisture” “no excessive exfoliation — ISDIN Retinal Intense Serum” “Suitable for sensitive skin — Theramid DERMA-PEPTIDES” “incredibly gentle... I experienced zero redness or irritation — Theramid Copper Peptide”
- Hydration, Plumping, and Barrier Repair Often Mentioned Often Mentioned “Improved moisture and texture — ISDIN Hyaluronic Moisture” “Skin feels intensely hydrated — ISDIN Hyaluronic Concentrate” “Only thing that got my barrier under control — Theramid Ceramide Treatment” “Provides long-lasting hydration — Theramid Ceramide Treatment”
- Visible Anti-Aging and Firmness Rarely Noted Mostly Mentioned “Fine lines are less visible — Theramid DERMA-PEPTIDES” “my skin feels incredibly fed and plump — Theramid Copper Peptide” “softening fine lines — ISDIN Retinal Intense Serum”
- Makeup Compatibility and Finish Often Mentioned Not noted “acts like a primer — ISDIN Eryfotona Actinica” “dries down matte — ISDIN Eryfotona Actinica” “My skin felt sooo hydrated and looks so plump and dewey. — ISDIN Fusion Water”
- High Price and Value Concerns Often Mentioned Rarely Noted “Didn't work better than cheaper options — Theramid Ceramide Treatment” “very expensive — ISDIN Eryfotona Actinica”
- Fragrance and Scent Issues Often Mentioned Rarely Noted “Didn't like the scent — Theramid Ceramide Treatment” “smell is overpowering — ISDIN Eryfotona Actinica”

## Questions and answers

### ISDIN or Theramid: which is better?

ISDIN and Theramid each excel in different areas, with ISDIN standing out for its makeup-friendly sunscreens and Theramid offering stronger visible anti-aging and firmness benefits according to reviewer themes.

### What is the difference between ISDIN and Theramid?

ISDIN and Theramid are both Spanish skincare brands, but ISDIN was founded in 1975 and is known for its makeup-friendly sunscreens, while Theramid is a newer brand founded in 2022 that does better for visible anti-aging and firmness. The products on this page from Theramid are entirely fragrance-free, whereas several ISDIN products include fragrance in their formulas.

### ISDIN or Theramid: which moisturizer is better?

When comparing moisturizers, ISDIN and Theramid each have distinct options on this page, but Theramid is noted for better results in visible anti-aging and barrier repair. Lovi rates Theramid Ceramide Treatment with a Superior fit for dry sensitive skin and High for dry skin, while ISDIN offers options like Hyaluronic Moisture with average fits across most skin types.

[Scientific Reports, 2022](https://pubmed.ncbi.nlm.nih.gov/35340018/) [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Which is more affordable, ISDIN or Theramid?

Reviewers note that both ISDIN and Theramid come with high price and value concerns, making affordability a common issue across both brands.

### Which causes fewer breakouts, ISDIN or Theramid?

ISDIN and Theramid are equal when it comes to being gentle on sensitive skin and non-irritating. The products on this page for both brands offer options that help with acne-prone skin, such as ISDIN Eryfotona Actinica and Theramid [Copper Peptide](https://lovi.care/skincare/au/ingredients/copper-peptide).

### How do the founding years and corporate ownerships of ISDIN and Theramid compare?

ISDIN was founded in 1975 in Spain and is owned by Puig, whereas Theramid was founded in 2022 in Spain and is owned by the Cosnova Group.

### Which brand has more fragrance-free products according to the page?

Theramid has more fragrance-free products on this page, as every Theramid product lists no fragrance in its ingredients. In contrast, five of the eight ISDIN products on this page contain fragrance.

### How does the Lovi fit level of Ceramide Treatment differ between dry sensitive skin and oily skin?

Ceramide Treatment has a Superior Lovi fit for dry sensitive skin. Its fit for oily skin is Average.

[Scientific Reports, 2022](https://pubmed.ncbi.nlm.nih.gov/35340018/)

## Research behind their key ingredients

- [Hyaluronic acid and wound healing](https://pubmed.ncbi.nlm.nih.gov/25877441/) Sodium hyaluronate · Journal of Pharmacy & Pharmaceutical Sciences, 2015
- [Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage](https://pubmed.ncbi.nlm.nih.gov/28155509/) Antioxidants · Drug Delivery, 2017
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Ascorbic acid, Tocopherol · Journal of Cosmetic Dermatology, 2020
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Bakuchiol · The British Journal of Dermatology, 2019
- [Moisturizing and Antiinflammatory Properties of Cosmetic Formulations Containing Centella asiatica Extract](https://pubmed.ncbi.nlm.nih.gov/27168678/) Madecassic acid · Indian Journal of Pharmaceutical Sciences, 2016
- [Alteration of barrier properties, stratum corneum ceramides and microbiome composition in response to lotion application on cosmetic dry skin](https://pubmed.ncbi.nlm.nih.gov/35340018/) Ceramide · Scientific Reports, 2022
- [Antiaging efficacy of melatonin-based day and night creams: a randomized, split-face, assessor-blinded proof-of-concept trial](https://pubmed.ncbi.nlm.nih.gov/29416368/) Melatonin · Clinical, Cosmetic and Investigational Dermatology, 2018
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin, Madecassic acid · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [The Effects of a Standardized Extract of Centella asiatica on Postlaser Resurfacing Wound Healing on the Face: A Split-Face, Double-Blind, Randomized, Placebo-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/32310680/) Madecassic acid · Journal of Alternative and Complementary Medicine, 2020
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [Stable Ozonides with Vitamin E Acetate versus Corticosteroid in the Treatment of Lichen Sclerosus in Foreskin: Evaluation of Effects on Inflammation](https://pubmed.ncbi.nlm.nih.gov/30991399/) Tocopheryl acetate · Urologia Internationalis, 2019
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [Systematic Study of Paeonol/Madecassoside Co-Delivery Nanoemulsion Transdermal Delivery System for Enhancing Barrier Repair and Anti-Inflammatory Efficacy](https://pubmed.ncbi.nlm.nih.gov/37446936/) Centella asiatica · Molecules, 2023
- [Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles in acne treatment: A preclinical and clinical approach](https://pubmed.ncbi.nlm.nih.gov/40254135/) Zinc oxide · Journal of Controlled Release, 2025
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [The pivotal role of Bifida Ferment Lysate on reinforcing the skin barrier function and maintaining homeostasis of skin defenses in vitro](https://pubmed.ncbi.nlm.nih.gov/37218728/) Bifida lysate ferment · Journal of Cosmetic Dermatology, 2023
- [Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications](https://pubmed.ncbi.nlm.nih.gov/25817264/) Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7 · Journal of Cosmetic Dermatology, 2015
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022
- [Effects of 1,3-propanediol associated, or not, with butylene glycol and/or glycerol on skin hydration and skin barrier function](https://pubmed.ncbi.nlm.nih.gov/37699769/) Propanediol · International Journal of Cosmetic Science, 2024
- [Positive and ecobiological contribution in skin photoprotection of ectoine and mannitol combined in vivo with UV filters](https://pubmed.ncbi.nlm.nih.gov/37539499/) Ectoin · Journal of Cosmetic Dermatology, 2024
- [Comparison of methods for assessing photoprotection against ultraviolet A in vivo](https://pubmed.ncbi.nlm.nih.gov/3819071/) Butyl methoxydibenzoylmethane · Journal of the American Academy of Dermatology, 1987
- [Using ordered mesoporous silica SBA-15 to limit cutaneous penetration and transdermal permeation of organic UV filters](https://pubmed.ncbi.nlm.nih.gov/31437563/) Butyl methoxydibenzoylmethane · International Journal of Pharmaceutics, 2019
- [Topical Zinc Oxide Nanoparticle Formulations for Acne Vulgaris: A Systematic Review of Pre-Clinical and Early-Phase Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/41007718/) Zinc oxide · Biomedicines, 2025
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Enhancing Photoprotection and Mitigating Ex Vivo Stratum Corneum Oxidative Stress: A Multifunctional Strategy Combining Rosmarinic Acid with UVB Filters](https://pubmed.ncbi.nlm.nih.gov/40227214/) Octocrylene · Antioxidants, 2025
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025
- [TiO2-embedded mesoporous silica with lower porosity is beneficial to adsorb the pollutants and retard UV filter absorption: A possible application for outdoor skin protection](https://pubmed.ncbi.nlm.nih.gov/36455708/) Butyl methoxydibenzoylmethane · European Journal of Pharmaceutical Sciences, 2023
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Ginkgo biloba leaves extract's cosmeceutical evaluation: a preliminary assessments on human volunteers towards achieving improved skin condition and rejuvenation](https://pubmed.ncbi.nlm.nih.gov/37074796/) Ginkgo biloba leaf extract · Drug Development and Industrial Pharmacy, 2023
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery](https://pubmed.ncbi.nlm.nih.gov/36279763/) Hydrolyzed hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [Facial disbiosis and UV filters](https://pubmed.ncbi.nlm.nih.gov/39499337/) Ethylhexyl salicylate · Archives of Dermatological Research, 2024
- [The clinical efficacy of a new emulsion for acne and conspicuous facial pore amelioration](https://pubmed.ncbi.nlm.nih.gov/38140770/) Lens esculenta seed extract · Journal of Cosmetic Dermatology, 2024
- [Retrospective Review of Dermal Safety Studies of Organic Sunscreens](https://pubmed.ncbi.nlm.nih.gov/40911743/) Ethylhexyl salicylate · Journal of Drugs in Dermatology, 2025
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026
- [Mechanistic understanding and peptide ingredient screening for type III collagen via biological knowledge graph and molecular docking](https://pubmed.ncbi.nlm.nih.gov/42683869/) Palmitoyl tetrapeptide-7, Palmitoyl tripeptide-1 · International Journal of Cosmetic Science, 2026
- [Prospective, Randomized, Double-Blind Assessment of Supramolecular Bakuchiol and Terminalia Chebula Extract for Facial Photoaging in Chinese Sensitive Skin Population](https://pubmed.ncbi.nlm.nih.gov/41424674/) Bakuchiol · Health Science Reports, 2025
- [Augmented Skin Beneficial Effects of Thermus Thermophilus and Bacillus Subtilis Mixed-Culture Ferment Extract by Tripeptide GHK-Cu](https://pubmed.ncbi.nlm.nih.gov/42573538/) Copper tripeptide-1 · Skin Research and Technology, 2026

## The brands

- Spanish skincare: [ISDIN](https://lovi.care/skincare/au/brands/isdin)
- Spanish skincare: [Theramid](https://lovi.care/skincare/au/brands/theramid)

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## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

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