# Galderma vs Sebamed

Page: https://lovi.care/skincare/au/compare/galderma-vs-sebamed

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Australia.

Galderma and Sebamed are established European skincare houses known for addressing distinct dermatological needs through targeted formulations. The Swiss pioneer focuses on potent [serums](https://lovi.care/skincare/au/ingredients/serum) tailored for oily, acne-prone, and mature complexions, with top ratings for Epiduo Gel and Benzac variants. Meanwhile, the German brand champions gentle cleansers and thoughtful moisturizers using scientifically balanced, skin-neutral pH formulas to support reactive and sensitive skin. While both prioritize clinical efficacy, the former emphasizes intensive active treatments, whereas the latter centers its steady approach on foundational barrier health.

Galderma is a Swiss skincare brand founded in 1981 and owned by Galderma Group AG.

[en.wikipedia.org](https://en.wikipedia.org/wiki/Galderma)

Sebamed is a German skincare brand founded in 1967 and owned by Sebapharma GmbH & Co. KG.

[sebamed.ae](https://sebamed.ae/en/article/2/Sebapharma) [sebamed.com](https://sebamed.com/en/info/company/about-us/) [en.wikipedia.org](https://en.wikipedia.org/wiki/Sebamed) [de.wikipedia.org](https://de.wikipedia.org/wiki/Sebamed)

This page compares some of the most popular Galderma and Sebamed products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg22aa678d06).

### Popular Galderma vs Sebamed products

#### Galderma

- [Epiduo Gel](https://lovi.care/skincare/au/p/galderma/epiduo-gel/for/acne-prone-skin) — High fit
- [Benzac AC 5](https://lovi.care/skincare/au/p/galderma/benzac-ac-5/for/oily-acne-prone-skin) — High fit — [A$25.49 at Amazon](https://www.amazon.com.au/dp/B076VMBQKP?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
- [Benzac AC Mild Strength 2.5% Acne Gel](https://lovi.care/skincare/au/p/galderma/benzac-ac-mild-strength-2-5-acne-gel/for/oily-acne-prone-skin) — High fit — [A$24.59 at Amazon](https://www.amazon.com.au/dp/B08GKHH72J?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)

#### Sebamed

- [Clear Face Care Gel](https://lovi.care/skincare/au/p/sebamed/clear-face-care-gel/for/oily-acne-prone-skin) — High fit
- [Facial Cleanser](https://lovi.care/skincare/au/p/sebamed/facial-cleanser/for/combination-skin) — High fit

## Questions and answers

### Galderma or Sebamed: which is better?

Galderma is better for oily and acne-prone skin, as Lovi rates its acne-clearing [serums](https://lovi.care/skincare/au/ingredients/serum) High for these skin types, though reviewers note they may cause severe dryness and irritation. Sebamed is a good alternative when you want gentle cleansers and moisturizers suitable for combination and sensitive skin.

[The Cochrane Database of Systematic Reviews, 2020](https://pubmed.ncbi.nlm.nih.gov/32175593/) [American Journal of Clinical Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29549588/)

### What is the difference between Galderma and Sebamed?

Galderma has a High Lovi fit for oily and acne-prone skin with its effective acne-clearing serums, whereas Sebamed offers a High fit for combination and sensitive skin with its gentle products on this page.

[The Cochrane Database of Systematic Reviews, 2020](https://pubmed.ncbi.nlm.nih.gov/32175593/) [American Journal of Clinical Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29549588/)

### Which is more affordable, Galderma or Sebamed?

The provided page and studies do not contain pricing information, so it is not possible to determine whether Galderma or Sebamed is more affordable.

### Which causes fewer breakouts, Galderma or Sebamed?

Galderma has a High fit level for oily and acne-prone skin with the products on this page, whereas Sebamed has an Average fit level for acne-prone skin. [Benzoyl peroxide](https://lovi.care/skincare/au/ingredients/benzoyl-peroxide) in Galderma treatments helps reduce acne.

[The Cochrane Database of Systematic Reviews, 2020](https://pubmed.ncbi.nlm.nih.gov/32175593/) [Journal of Shoulder and Elbow Surgery, 2021](https://pubmed.ncbi.nlm.nih.gov/33545336/)

### Which brand was founded earlier, Galderma or Sebamed?

Sebamed was founded earlier in 1967 in Germany, while Galderma was founded later in 1981 in Switzerland.

### Do any of the products from Galderma or Sebamed contain fragrance?

Every product from Galderma and Sebamed on this page lists no fragrance in its ingredients.

### Which brand has products specifically rated as having a High Lovi fit for dry skin?

Neither brand has products on this page rated as having a High Lovi fit for dry skin, as Galderma's dry skin fits range from Low to Caution and Sebamed's are Average.

## Research behind their key ingredients

- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [The effects of a topical gel containing chitosan, 0,2% chlorhexidine, allantoin and despanthenol on the wound healing process subsequent to impacted lower third molar extraction](https://pubmed.ncbi.nlm.nih.gov/27475700/) Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice · Clinical Pharmacology, 2018
- [Topical benzoyl peroxide for acne](https://pubmed.ncbi.nlm.nih.gov/32175593/) Benzoyl peroxide, Benzoyl peroxide 25mg g · The Cochrane Database of Systematic Reviews, 2020
- [Prevention and Reduction of Atrophic Acne Scars with Adapalene 0.3%/Benzoyl Peroxide 2.5% Gel in Subjects with Moderate or Severe Facial Acne: Results of a 6-Month Randomized, Vehicle-Controlled Trial Using Intra-Individual Comparison](https://pubmed.ncbi.nlm.nih.gov/29549588/) Adapalene · American Journal of Clinical Dermatology, 2018
- [Benzoyl peroxide treatment decreases Cutibacterium acnes in shoulder surgery, from skin incision until wound closure](https://pubmed.ncbi.nlm.nih.gov/33545336/) Benzoyl peroxide, Benzoyl peroxide 25mg g · Journal of Shoulder and Elbow Surgery, 2021
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Efficacy and Safety of a Fixed-Dose Clindamycin Phosphate 1.2%, Benzoyl Peroxide 3.1%, and Adapalene 0.15% Gel for Moderate-to-Severe Acne: A Randomized Phase II Study of the First Triple-Combination Drug](https://pubmed.ncbi.nlm.nih.gov/34674160/) Benzoyl peroxide, Benzoyl peroxide 25mg g · American Journal of Clinical Dermatology, 2022
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [A topical gel of tea tree oil nanoemulsion containing adapalene versus adapalene marketed gel in patients with acne vulgaris: a randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/34251536/) Adapalene · Archives of Dermatological Research, 2022
- [Development of Multifunctional Cosmetic Cream Using Bioactive Materials from Streptomyces sp. T65 with Synthesized Mesoporous Silica Particles SBA-15](https://pubmed.ncbi.nlm.nih.gov/32224894/) Silicon dioxide · Antioxidants, 2020
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin](https://pubmed.ncbi.nlm.nih.gov/11684194/) Witch hazel bark extract · Phytochemistry, 2001
- [Formulating octyl methoxycinnamate in hybrid lipid-silica nanoparticles: An innovative approach for UV skin protection](https://pubmed.ncbi.nlm.nih.gov/32395645/) Silicon dioxide · Heliyon, 2020
- [Clindamycin phosphate 1.2%/adapalene 0.15%/benzoyl peroxide 3.1% gel for moderate-to-severe acne: Efficacy and safety results from two randomized phase 3 trials](https://pubmed.ncbi.nlm.nih.gov/37656094/) Adapalene · Journal of the American Academy of Dermatology, 2023
- [Efficacy and safety of microencapsulated benzoyl peroxide and microencapsulated tretinoin for the treatment of acne vulgaris: Results from two phase 3 double-blind, randomized, vehicle-controlled studies](https://pubmed.ncbi.nlm.nih.gov/37356627/) Benzoyl peroxide, Benzoyl peroxide 25mg g · Journal of the American Academy of Dermatology, 2023
- [Semi-Solid Dosage Forms Containing Pranoprofen-Loaded NLC as Topical Therapy for Local Inflammation: In Vitro, Ex Vivo and In Vivo Evaluation](https://pubmed.ncbi.nlm.nih.gov/37367119/) Carbomer 940 · Gels, 2023
- [Effect of seasonal and geographical differences on skin and effect of treatment with an osmoprotectant: Sorbitol](https://pubmed.ncbi.nlm.nih.gov/23752031/) Sorbitol · Journal of Cosmetic Science, 2013
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025

## The brands

- Swiss skincare: [Galderma](https://lovi.care/skincare/au/brands/galderma)
- German skincare: [Sebamed](https://lovi.care/skincare/au/brands/sebamed)

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- [The Ordinary vs Galderma](https://lovi.care/skincare/au/compare/the-ordinary-vs-galderma)
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- [CeraVe vs Galderma](https://lovi.care/skincare/au/compare/cerave-vs-galderma)
- [CeraVe vs Sebamed](https://lovi.care/skincare/au/compare/cerave-vs-sebamed)
- [La Roche-Posay vs Galderma](https://lovi.care/skincare/au/compare/la-roche-posay-vs-galderma)
- [La Roche-Posay vs Sebamed](https://lovi.care/skincare/au/compare/la-roche-posay-vs-sebamed)
- [Dr. Althea vs Galderma](https://lovi.care/skincare/au/compare/dr-althea-vs-galderma)
- [Dr. Althea vs Sebamed](https://lovi.care/skincare/au/compare/dr-althea-vs-sebamed)
- [Some By Mi vs Galderma](https://lovi.care/skincare/au/compare/some-by-mi-vs-galderma)
- [Some By Mi vs Sebamed](https://lovi.care/skincare/au/compare/some-by-mi-vs-sebamed)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/galderma-vs-sebamed
- United Kingdom: https://lovi.care/skincare/uk/compare/galderma-vs-sebamed
- Ireland: https://lovi.care/skincare/ie/compare/galderma-vs-sebamed
- Germany: https://lovi.care/skincare/de/compare/galderma-vs-sebamed
- France: https://lovi.care/skincare/fr/compare/galderma-vs-sebamed
- Italy: https://lovi.care/skincare/it/compare/galderma-vs-sebamed
- Netherlands: https://lovi.care/skincare/nl/compare/galderma-vs-sebamed
- Spain: https://lovi.care/skincare/es/compare/galderma-vs-sebamed
- Canada: https://lovi.care/skincare/ca/compare/galderma-vs-sebamed
- Australia: https://lovi.care/skincare/au/compare/galderma-vs-sebamed (this page)
- Singapore: https://lovi.care/skincare/sg/compare/galderma-vs-sebamed
- Saudi Arabia: https://lovi.care/skincare/sa/compare/galderma-vs-sebamed
- United Arab Emirates: https://lovi.care/skincare/ae/compare/galderma-vs-sebamed
