Tatcha The Silk Sunscreen SPF 50 for combination skin

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Questions and answers

What the research says

• Hyaluronic acid extracts are safe and efficacious products for skin repair when used in tissue regeneration alone or in combination with herbal or Western medicine.

  Journal of Pharmacy & Pharmaceutical Sciences, 2015

• Optimized transfersomes loaded with epigallocatechin-3-gallate and hyaluronic acid increased cell viability while reducing lipid peroxidation, intracellular ROS, and MMP expression in HaCaT cells, and exhibited higher skin permeation and deposition compared to plain EGCG.

  Drug Delivery, 2017

• Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles selectively inhibited C. acnes, outperformed erythromycin in preclinical acne models, and safely reduced acne lesions and redness in a clinical trial.

  Journal of Controlled Release, 2025

• Topical treatment of nicotinamide, alone or in combination with other active ingredients, reduces the progression of skin aging and hyperpigmentation in clinical trials while being well tolerated.

  Antioxidants, 2021

• Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.

  Journal of Cosmetic Dermatology, 2021

• Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.

  The Journal of Investigative Dermatology, 2008

• Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.

  Dermatologic Surgery, 2005

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• Topical 0.5% hyaluronic-ZnO nanogel applied twice daily reduced inflammatory-lesion counts by 58% at week four in human subjects compared to baseline without causing erythema.

  Biomedicines, 2025

• Nels cream achieved a similar reduction in inflammatory and noninflammatory lesion counts compared to 5% benzoyl peroxide in acne vulgaris patients, but caused significantly fewer side-effects such as peeling and dryness.

  Clinical and Experimental Dermatology, 2000

• Topically applied coated and uncoated zinc oxide nanoparticles under flexing and massage are retained in the stratum corneum with no significant penetration into the viable epidermis and no cellular toxicity in human skin.

  Nanomedicine, 2016

• Bacterial cellulose wound dressing containing silk sericin and PHMB improved wound quality and reduced pain compared to Bactigras in patients with split-thickness skin graft donor-site wounds.

  Archives of Dermatological Research, 2018

• A bacterial nanocellulose wound dressing incorporating polyhexamethylene biguanide and sericin showed no skin irritation in healthy volunteers and significantly promoted wound healing with lower wound size and higher collagen formation in full-thickness rat wounds compared to controls.

  Archives of Dermatological Research, 2016

• Topical application of sericin gels increased skin intrinsic moisturization, hydroxyproline content, and epidermal hydration while decreasing transepidermal water loss and skin impedance in healthy human volunteers.

  Journal of Cosmetic Dermatology, 2005

• Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts.

  Molecules, 2025

• Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway.

  Antioxidants, 2025

Ingredients

Zinc Oxide, Water, C12-15 Alkyl Benzoate, Caprylic Capric Triglyceride, Lauryl Peg-8 Dimethicone, Dimethicone, Isododecane, Tridecyl Salicylate, Hdi Trimethylol Hexyllactone Crosspolymer, Propanediol, Caprylyl Methicone, Polymethylsilsesquioxane, Niacinamide, Saccharomyces Rice Ferment Filtrate, Silica, Squalane, Camellia Sinensis Leaf Extract, Cladosiphon Okamuranus Extract, Hydrolyzed Silk, Bisabolol, Allantoin, Tocopherol, Theobroma Cacao Seed Extract, Arctium Lappa Root Extract, Kappaphycus Alvarezii Extract, Sodium Hyaluronate, Lecithin, Caesalpinia Spinosa Fruit Extract, Lactobacillus, Maltodextrin, Caprylyl Glycol, Dimethicone Crosspolymer, Hydrogenated Lecithin, Tetrasodium Glutamate Diacetate, Peg-10, Polyglyceryl-2 Dipolyhydroxystearate, Propylene Glycol, Lauryl Peg-10 Tris Trimethylsiloxy Silylethyl Dimethicone, Polyglyceryl-4 Diisostearate Polyhydroxystearate Sebacate, Butylene Glycol, Phosphoric Acid, Sodium Hydroxide, Sodium Chloride, Hexylene Glycol, Ethylhexylglycerin, Phenoxyethanol

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.