# SU:M37 Losec Summa Elixir Night Ampoule for mature skin **Lovi Fit: Average fit for mature skin.** Normal Skin Fit: High · Effectiveness: Average · Safety: High. Page: https://lovi.care/skincare/ae/p/su-m37/losec-summa-elixir-night-ampoule/for/mature-skin The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Arab Emirates. Brand: [SU:M37](https://lovi.care/skincare/ae/brands/su-m37) Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/ae/best/moisturizers) This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app. Works for mature skin; other moisturizers fit it better. ## Why this fit - Offers excellent moisturizing treatment for your normal skin, with glycerin and panthenol enhancing barrier resilience and hydration. Numerous fermented ingredients and botanical extracts provide antioxidant activity and support skin barrier repair, making it highly suitable for your skin type. - While beneficial for general hydration, the formulation does not specifically target your concerns of wrinkles and fine lines. - The product is safe for your normal skin, as it lacks harsh ingredients and includes soothing components like Beta-Glucan and Centella Asiatica Extract. ## Fit by skin type - [Oily skin](https://lovi.care/skincare/ae/p/su-m37/losec-summa-elixir-night-ampoule/for/oily-skin): Average - [Dry skin](https://lovi.care/skincare/ae/p/su-m37/losec-summa-elixir-night-ampoule/for/dry-skin): Average - [Combination skin](https://lovi.care/skincare/ae/p/su-m37/losec-summa-elixir-night-ampoule/for/combination-skin): Average - [Sensitive skin](https://lovi.care/skincare/ae/p/su-m37/losec-summa-elixir-night-ampoule/for/sensitive-skin): Average - [Acne-prone skin](https://lovi.care/skincare/ae/p/su-m37/losec-summa-elixir-night-ampoule/for/acne-prone-skin): Average - [Skin with dark spots](https://lovi.care/skincare/ae/p/su-m37/losec-summa-elixir-night-ampoule/for/dark-spots): Average - [Mature skin](https://lovi.care/skincare/ae/p/su-m37/losec-summa-elixir-night-ampoule/for/mature-skin): Average (this page) - [Dry sensitive skin](https://lovi.care/skincare/ae/p/su-m37/losec-summa-elixir-night-ampoule/for/dry-sensitive-skin): Average - [Oily acne-prone skin](https://lovi.care/skincare/ae/p/su-m37/losec-summa-elixir-night-ampoule/for/oily-acne-prone-skin): Average ## Key ingredients Lactobacillus Soybean Extract Ferment, Panthenol, Gold, Wine Extract, Beta-Glucan ## What the research says - Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)) - A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)) - A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)) - Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)) - Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)) - ANT1 soybean extract cream ameliorated complications and enhanced skin recovery after Nd:YAG laser therapy in 45 Asian women, with higher concentrations significantly reducing wrinkles, spots, and pores compared to placebo. ([Annals of Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29369914/)) - Genistein and daidzein inhibited UVB-induced hydrogen peroxide production in keratinocytes acting as free radical scavengers with negligible skin disruption, whereas glycitein showed no protective activity. ([International Journal of Pharmaceutics, 2008](https://pubmed.ncbi.nlm.nih.gov/18761396/)) - A phytoestrogen-enriched cosmetic formulation containing biotransformed soybean extract increased collagen-I expression in fibroblast cells and skin explants in an estrogen receptor beta-dependent manner without harming skin microbiota. ([Brazilian Journal of Medical and Biological Research = Revista Brasileira de Pesquisas Medicas E Biologicas, 2023](https://pubmed.ncbi.nlm.nih.gov/37878883/)) - Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/)) - Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/)) - Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two. ([Auris, Nasus, Larynx, 2020](https://pubmed.ncbi.nlm.nih.gov/32067777/)) - Topically delivered gold-coated silica microparticles combined with laser pulses reduced inflammatory lesions compared with sham treatments in patients with moderate-to-severe facial acne. ([The Journal of Investigative Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25748556/)) - Laser-activated gold microparticles combined with topical retinoids reduced inflammatory lesion counts by 68% at month 12 in 52 patients with mild-to-moderate inflammatory facial acne. ([Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37943275/)) - Combined treatment with a micro-diamond and micro-gold topical serum and a 1064 nm picosecond Nd:YAG laser produced moderate clinical improvement and high participant satisfaction in 40% of participants for facial skin rejuvenation with minimal side effects. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/35304935/)) - Treatment with Jacquez grapes wine extract protected a three-dimensional tissue culture model of human epidermis against UVB-induced oxidative damage by preventing ROS-mediated alterations. ([Toxicology in Vitro, 2006](https://pubmed.ncbi.nlm.nih.gov/16901675/)) - The V. vinifera skin extract (ACH37) scavenged reactive oxygen species, prevented inflammation, modulated extracellular matrix remodeling, increased telomere length and telomerase activity, and reversed UV-induced gene suppression in in vitro and ex vivo assays. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37464908/)) - Skin care regimens containing beta-glucan improved hemoglobin index, skin hydration, and transepidermal water loss compared to vehicle control in 20 patients undergoing fractional laser therapy. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33128496/)) - Treatment with topical formulations containing beta-glucan combined with nanofractional radiofrequency plus magnetic nanofractional radiofrequency showed the best efficacy and was tolerable and effective in Chinese women with abdominal stretch marks compared to control groups. ([Dermatology and Therapy, 2023](https://pubmed.ncbi.nlm.nih.gov/37171578/)) - Topical beta-glucan mildly improved striae gravidarum, 1565-nm non-ablative fractional laser showed better results than topical beta-glucan, and the combined strategy further improved striae gravidarum atrophy compared to single treatment. ([The Journal of Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35570397/)) ## Why other moisturizers fit mature skin better - Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/)) - Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)) - Treatment with a combination of niacinamide and hyaluronic acid improved skin aging signs and demonstrated a senomorphic effect by decreasing SASP and autocrine signaling genes in women. ([Scientific Reports, 2024](https://pubmed.ncbi.nlm.nih.gov/39009698/)) ## What reviewers say Based on limited data, this night ampoule is highly rated for providing intensive hydration and a radiant glow, particularly for dry or mature skin. Users appreciate its luxurious texture and skin barrier repair benefits. However, the high price point and the presence of essential oils and alcohol are noted concerns, with some experiencing a heavy finish or availability issues. - Liked: Intensive hydration (mostly mentioned) - Liked: Radiance and glow (often mentioned) - Disliked: High price point (often mentioned) - Liked: Luxurious texture (sometimes noted) - Liked: Skin barrier repair (sometimes noted) - Disliked: Availability issues (sometimes noted) - Disliked: Potential irritants (sometimes noted) - Disliked: Heavy/sticky finish (rarely noted) ## How to apply - Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help smooth fine lines. - Apply this product after your toner and serum, but before your SPF in the morning. Follow your cleanser and toner steps to keep your skin balanced. - Gently press a small amount into your face and neck. Avoid rubbing the skin too harshly to prevent extra tension. - Apply the moisturizer on slightly damp skin to help lock in extra moisture. Clean skin helps the product absorb much more evenly. - Avoid the sensitive eye area during application. Do a quick patch test before your very first use to stay safe. - Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4 ## Questions and answers ### How well does SU:M37 Losec Summa Elixir Night Ampoule work for mature skin? This moisturizing treatment works for mature skin, though other products fit it better. To fit mature skin well, a product of this type needs effective anti-wrinkle ingredients alongside hydrating agents like glycerin and panthenol. Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/) ### Which ingredients make this serum a good fit for mature skin? This moisturizing treatment works well for mature skin thanks to hydrating and soothing components like glycerin, panthenol, Beta-Glucan, and Centella Asiatica Extract, which help improve moisture and support skin barrier repair. However, for a mature skin type, a product of this type also needs dedicated anti-wrinkle ingredients to effectively target fine lines and wrinkles. Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/) ### What does Lactobacillus Soybean Extract Ferment do for mature skin? Lactobacillus Soybean Extract Ferment is not a strong match for mature skin because it lacks the targeted firming ingredients and deep nourishment this skin type needs to stay smooth and soft. ### What does Panthenol do for mature skin? Panthenol helps mature skin by increasing moisture and reducing water loss, which makes the skin feel softer and smoother. It also improves elasticity and reduces the appearance of wrinkles while soothing irritation. Sources: [Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29577586/), [Lasers in Medical Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42686896/) ### Where does this serum go in a skincare routine for mature skin? This treatment goes in the evening routine after cleansing and toning, and before moisturizing. To better fit mature skin, this type of product needs targeted wrinkle-smoothing ingredients and actives. ### Can I use this serum with retinol, and in what order? You can use this moisturizing treatment in the evening before your retinol to help your skin adjust. Applying a hydrating barrier product like this first may reduce dryness and irritation while supporting your skin. Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/) ### How often should I use this serum? This treatment is intended for evening use as part of your routine. While it provides good moisture and soothing benefits, a product for mature skin also needs targeted anti-aging ingredients like retinoids or peptides to help smooth out wrinkles and fine lines. Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/) ### Can this serum clog pores, cause breakouts or purging for mature skin? This moisturizing treatment is unlikely to clog pores or cause breakouts for mature skin since it lacks harsh ingredients and includes soothing components like beta-glucan and Centella Asiatica extract. To better address mature skin concerns like wrinkles and fine lines, a product of this type needs targeted ingredients like retinol, peptides, or concentrated antioxidants. Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/) ### Can I use this serum around the eyes or on my body? You can use this moisturizing treatment around the eyes and on your body, as it has a very safe formula with soothing components like beta-glucan and Centella Asiatica extract. To properly fit mature skin, a product of this type needs concentrated anti-aging ingredients and botanical extracts that target wrinkles and fine lines. ### Is this serum fragrance-free and alcohol-free? It has no fragrance and contains drying alcohol (alcohol denat). ## Alternatives for mature skin - [MISSHA Super Aqua Ultra Hyalron Ampoule](https://lovi.care/skincare/ae/p/missha/super-aqua-ultra-hyalron-ampoule/for/mature-skin) — High fit — AED 107.99 at Amazon - [COSRX Hydrium Triple Hyaluronic Moisture Ampoule](https://lovi.care/skincare/ae/p/cosrx/hydrium-triple-hyaluronic-moisture-ampoule/for/mature-skin) — Average fit — AED 60.00 at Amazon - [Torriden DIVE-IN Low Molecular Hyaluronic Acid Serum](https://lovi.care/skincare/ae/p/torriden/dive-in-low-molecular-hyaluronic-acid-serum/for/mature-skin) — Average fit — AED 45.00 at Amazon ## Pairs well with - Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ae/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — AED 84.53 at Amazon - Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/ae/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — AED 65.43 at Amazon - SPF: [SKIN1004 MADAGASCAR CENTELLA AIR-FIT SUNCREAM PLUS](https://lovi.care/skincare/ae/p/skin1004/madagascar-centella-air-fit-suncream-plus/for/mature-skin) — Superior fit — AED 39.45 at Amazon ## Where to buy No store in United Arab Emirates has a checked price for this product, so the page shows none. ## Ingredients Water, Glycerin, Propanediol, Alcohol Denat, 1,2-Hexanediol, Butylene Glycol, Lactobacillus Soybean Extract Ferment, Chondrus Crispus Extract, Bis-Peg-18 Methyl Ether Dimethyl Silane, Panthenol, Peg-40 Hydrogenated Castor Oil, Saccharomyces Barley Seed Ferment Filtrate, Saccharomyces Potato Extract Ferment Filtrate, Lauryl Dimethicone Polyglycerin-3 Crosspolymer, Polymethylsilsesquioxane, Tromethamine, Glyceryl Acrylate Acrylic Acid Copolymer, Wine Extract, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Carbomer, Polyquaternium-51, Gold, Euterpe Oleracea Fruit Extract, Vinegar, Bergamot Oil Fruit, Sodium Polyacrylate, Adenosine, Blueberry Fruit Extract, Lactobacillus Pear Juice Ferment Filtrate, Grapefruit Peel Oil, Lactobacillus Wasabia Japonica Extract Root Ferment, Saccharomyces Grape Extract Ferment, Lactobacillus Water Hyacinth Ferment, Lactobacillus Ginseng Root Ferment Filtrate, Lactobacillus Rye Flour Ferment, Saccharomyces Xylinum Black Tea Ferment, Monascus Rice Ferment, Trisodium Edta, Carthamus Tinctorius Flower Extract, Rosa Damascena Oil Flower, Phyllanthus Emblica Fruit Extract, Artemisia Annua Extract, Neem Leaf Extract, Beta-Glucan, Camellia Sinensis Leaf Extract, Elettaria Cardamomum Seed Oil, Cananga Odorata Oil Flower, Lavandula Angustifolia Oil Lavender Oil, Caprylic Capric Triglyceride, Pogostemon Cablin Oil, Salvia Officinalis Leaf Extract, Zingiber Officinale Root Extract, Clove Flower Extract, Yeast Extract Ferment, Lactobacillus Punica Granatum Extract Fruit Ferment, Diospyros Kaki Fruit Extract, Cucumis Sativus Fruit Extract, Melissa Officinalis Extract, Brassica Oleracea Capitata Leaf Extract, Rehmannia Glutinosa Root Extract, Morus Bombycis Leaf Extract, Ficus Carica Fruit Extract, Perilla Frutescens Leaf Extract, Geranium Robertianum Extract, Ipomoea Batatas Root Extract, Acorus Calamus Root Extract, Undaria Pinnatifida Extract, Pyrus Malus Fruit Extract, Leuconostoc Radish Root Extract, Fraxinus Excelsior Leaf Extract, Brassica Rapa Leaf Extract Turnip Leaf Extract, Rosmarinus Officinalis Leaf Extract Rosemary Leaf Extract, Nelumbo Nucifera Root Extract, Thymus Vulgaris Leaf Extract, Onion Bulb Extract, Portulaca Oleracea Extract, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Codonopsis Lanceolata Root Extract, Ginkgo Biloba Nut Extract, Lavandula Angustifolia Flower Extract Lavender Flower Extract, Sesamum Indicum Seed Extract, Citrus Unshiu Peel Extract, Grifola Frondosa Fruiting Body Extract, Fennel Fruit Extract, Daucus Carota Sativa Root Extract Carrot Root Extract, Parsley Extract, Platycodon Grandiflorum Root Extract, Watermelon Fruit Extract, Lonicera Japonica Flower Extract Honeysuckle Flower Extract, Eriobotrya Japonica Leaf Extract, Houttuynia Cordata Extract, Ocimum Basilicum Leaf Extract, Artemisia Princeps Leaf Extract, Panicum Miliaceum Seed Extract, Sasa Veitchii Leaf Extract, Acer Palmatum Leaf Extract, Glechoma Hederacea Extract, Schizonepeta Tenuifolia Extract, Chamomilla Recutita Flower Extract Matricaria Flower Extract, Anemarrhena Asphodeloides Root Extract, Equisetum Arvense Extract, Spinach Leaf Extract, Cassia Obtusifolia Seed Extract, Centella Asiatica Extract, Dandelion Leaf Extract, Camellia Japonica Leaf Extract, Trichosanthes Kirilowii Root Extract, Lycium Chinense Fruit Extract, Allium Sativum Bulb Extract, Illicium Verum Fruit Extract Anise Fruit Extract, Prunus Armeniaca Fruit Extract Apricot Fruit Extract, Citrus Junos Fruit Extract, Beta Vulgaris Root Extract, Musa Sapientum Fruit Extract, Rubus Idaeus Fruit Extract Raspberry Fruit Extract, Carica Papaya Fruit Extract, Phaseolus Angularis Seed Extract, Hemerocallis Fulva Flower Extract, Hypericum Perforatum Stem Extract Flower Leaf, Curcuma Longa Root Extract, Coriandrum Sativum Leaf Extract Fruit, Helianthus Annuus Seed Extract Sunflower Seed Extract, Nigella Sativa Seed Extract, Lentinus Edodes Extract, Cymbopogon Citratus Extract, Plantago Major Seed Extract, Marrubium Vulgare Extract, Cichorium Intybus Root Extract, Prunus Persica Fruit Extract, Peppermint Stem Extract Flower Leaf, Chaenomeles Sinensis Fruit Extract, Bergamot Leaf Extract, Lippia Citriodora Leaf Extract, Akebia Quinata Extract, Crataegus Cuneata Fruit Extract, Actinidia Polygama Fruit Extract, Prunus Salicina Fruit Extract, Jasminum Sambac Flower Extract Jasmine Flower Extract, Citrus Aurantium Dulcis Oil Flower, Cinnamomum Zeylanicum Bark Extract, Valeriana Officinalis Root Extract Rhizome, Honey Extract, Boswellia Serrata Extract Resin ## About the Lovi Fit Lovi: Unbiased, science-based skincare AI trained on real user outcomes. Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning. Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board). Page built Nov 8, 2026. 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