# SkinMedica Dermal Repair Cream for mature skin

**Lovi Fit: High fit for mature skin.**
Normal Skin Fit: Superior · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/ae/p/skinmedica/dermal-repair-cream/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Arab Emirates.

Brand: [SkinMedica](https://lovi.care/skincare/ae/brands/skinmedica)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/ae/best/moisturizers)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for mature skin; a few moisturizers fit it even better.

## Why this fit

- Excellent suitability for your normal skin is provided by Tetrahexyldecyl Ascorbate and Tocopheryl Acetate, which offer antioxidant activity and support barrier repair, addressing your wrinkles and fine lines.
- Sodium Hyaluronate and Retinyl Palmitate further enhance moisturizing and smoothing effects, contributing to a more hydrated and refined skin texture.
- The product is safe for your skin, with Aloe Barbadensis Leaf Juice and Algae Extract providing soothing benefits and no harsh ingredients present.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ae/p/skinmedica/dermal-repair-cream/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ae/p/skinmedica/dermal-repair-cream/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/ae/p/skinmedica/dermal-repair-cream/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/ae/p/skinmedica/dermal-repair-cream/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/ae/p/skinmedica/dermal-repair-cream/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/ae/p/skinmedica/dermal-repair-cream/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ae/p/skinmedica/dermal-repair-cream/for/mature-skin): High (this page)
- [Dry sensitive skin](https://lovi.care/skincare/ae/p/skinmedica/dermal-repair-cream/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/ae/p/skinmedica/dermal-repair-cream/for/oily-acne-prone-skin): Average

## Key ingredients

Tetrahexyldecyl Ascorbate, Sodium Hyaluronate, Aloe Barbadensis Leaf Juice, Dimethicone, Glycerin

## What the research says

- Retinyl palmitate-loaded non-ionic lamellar liquid crystalline systems provided a significant reduction of orbicular wrinkles in human volunteers compared to systems without retinyl palmitate. ([Colloids and Surfaces. B, Biointerfaces, 2011](https://pubmed.ncbi.nlm.nih.gov/21411295/))
- A vitamin A palmitate and antioxidant-containing oil-based moisturizer improved fine lines, wrinkles, pigmentation, tone, texture, dryness, firmness, and clarity across various body sites compared to a no-treatment group over 12 weeks. ([Journal of Cosmetic Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23438139/))
- Topical application of 1% Fucus vesiculosus extract gel twice daily for five weeks significantly decreased skin thickness and improved elasticity in human cheek skin compared with controls. ([Journal of Cosmetic Science, 2002](https://pubmed.ncbi.nlm.nih.gov/11917251/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Topical aloe vera gel significantly accelerated split-thickness skin graft donor-site healing compared to placebo in 12 patients, but showed no significant difference in pain relief. ([Plastic and Reconstructive Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29649056/))
- Topical application of Aloe vera cream reduced postoperative pain at rest and during defecation, accelerated wound healing at two weeks, and decreased analgesic requirements in patients after open hemorrhoidectomy compared to placebo. ([Journal of Alternative and Complementary Medicine, 2010](https://pubmed.ncbi.nlm.nih.gov/20569031/))
- Wearing an N95 mask alone compared to using dimethicone cream or hydrocolloid dressing caused more adverse skin reactions among 73 military health care workers, with no significant differences in fit test failure rates between groups. ([Military Medicine, 2024](https://pubmed.ncbi.nlm.nih.gov/38771104/))
- A dimethicone skin protectant lotion significantly decreased visual scoring and transepidermal water loss compared to vehicle control and SLS-only treated sites in 12 healthy humans exposed to sodium lauryl sulfate. ([Skin Research and Technology, 2000](https://pubmed.ncbi.nlm.nih.gov/11428946/))
- Treatment with a moisturizer containing dimethicone and glycerine increased epidermal thickness by 0.019 mm, improved barrier function by decreasing transepidermal water loss by 13%, decreased melanin intensity, and induced keratins 6 and 16 in fifteen women with moderately photoaged forearms. ([Clinical and Experimental Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17137484/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))

## What reviewers say

This product is highly praised for delivering intense, lasting hydration, significantly improving skin texture and softness, and promoting a more youthful appearance. It is particularly beneficial for dry, mature, or climate-stressed skin. Some users with oily or acne-prone skin find it too rich.

- Liked: Deeply hydrating (mostly mentioned)
- Liked: Improves texture (often mentioned)
- Liked: Anti-aging benefits (sometimes noted)
- Liked: Non-greasy feel (sometimes noted)
- Disliked: Expensive product (sometimes noted)
- Disliked: Causes breakouts (rarely noted)
- Disliked: Packaging issues (rarely noted)
- Disliked: Unpleasant scent (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help smooth fine lines.
- Apply this product after your toner and serum, but before your SPF in the morning. Follow your cleanser and toner steps to keep your skin balanced.
- Gently press a small amount into your face and neck. Avoid rubbing the skin too harshly to prevent extra tension.
- Apply the moisturizer on slightly damp skin to help lock in extra moisture. Clean skin helps the product absorb much more evenly.
- Avoid the sensitive eye area during application. Do a quick patch test before your very first use to stay safe.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes SkinMedica Dermal Repair Cream a great fit for mature skin?

SkinMedica Dermal Repair Cream is a great fit for mature skin because it features ingredients like Tetrahexyldecyl Ascorbate and Tocopheryl Acetate, which offer antioxidant activity and support barrier repair to address wrinkles and fine lines. Additionally, Sodium Hyaluronate and Retinyl Palmitate enhance hydration and smooth the skin texture, while Aloe Barbadensis Leaf Juice and Algae Extract provide soothing benefits.
Sources: [Colloids and Surfaces. B, Biointerfaces, 2011](https://pubmed.ncbi.nlm.nih.gov/21411295/)

### Which ingredients make this cream a good fit for mature skin?

Tetrahexyldecyl ascorbate and tocopheryl acetate make this cream a great fit by offering antioxidant support to address wrinkles and fine lines. Sodium hyaluronate and retinyl palmitate further enhance hydration and help smooth your skin texture.
Sources: [Colloids and Surfaces. B, Biointerfaces, 2011](https://pubmed.ncbi.nlm.nih.gov/21411295/)

### What does Vitamin C do for mature skin?

Vitamin C helps smooth out wrinkles, fade dark spots, and calm redness on mature skin. It also boosts collagen production to make skin firmer and protects against everyday environmental stress.
Sources: [The Journal of Clinical and Aesthetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/29104718/), [Dermatologic Surgery, 2002](https://pubmed.ncbi.nlm.nih.gov/11896774/)

### What does Hyaluronic Acid do for mature skin?

Hyaluronic acid helps mature skin by deeply boosting moisture, improving elasticity, and smoothing the appearance of fine lines and wrinkles. Regular use keeps the skin looking plump and soft while supporting overall firmness and hydration.
Sources: [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/), [Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38591218/)

### Where does this cream go in a skincare routine for mature skin?

This moisturizing treatment goes in the morning routine after a hydrating toner and before sunscreen, and in the evening routine after your treatment step. Daily use helps hydrate and smooth mature skin while offering antioxidant protection and soothing benefits.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/), [Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/36607762/)

### Can I use this cream with retinol, and in what order?

You can use this cream alongside retinol by applying the retinol first and following it with this moisturizer to help keep your skin comfortable. This routine helps smooth fine lines while minimizing dryness and irritation.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this cream?

SkinMedica Dermal Repair Cream is a great fit for mature skin and is generally applied twice daily as part of your morning and evening routine. Regular use helps keep dry skin hydrated and smooth while improving the look of fine lines and wrinkles.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Journal of Drugs in Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/26151786/)

### Can this cream clog pores, cause breakouts or purging for mature skin?

This moisturizing treatment is unlikely to clog pores or cause breakouts for mature skin, as it has a very low complaint rate for this issue. It features gentle ingredients like soothing aloe and hydrating hyaluronic acid to keep your skin calm and comfortable.

### Can I use this cream around the eyes or on my body?

This moisturizing treatment is well-suited for mature skin and can be used on the body, though extra care is needed around the thin skin of the eyes. Its hydrating ingredients help smooth fine lines and support skin structure safely.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37896378/)

### Is this cream fragrance-free and alcohol-free?

It contains fragrance (parfum, linalool, geraniol, and citronellol) and drying alcohol (alcohol denat).

## Alternatives for mature skin

- [Obagi Hydrate Luxe Moisture-Rich Cream](https://lovi.care/skincare/ae/p/obagi/hydrate-luxe/for/mature-skin) — Superior fit — AED 244.74 at Amazon
- [SKIN1004 Madagascar Centella Probio-Cica Enrich Cream](https://lovi.care/skincare/ae/p/skin1004/madagascar-centella-probio-cica-enrich-cream/for/mature-skin) — Superior fit — AED 34.80 at Amazon
- [L'Occitane Immortelle Divine Cream](https://lovi.care/skincare/ae/p/l-occitane/immortelle-divine-cream/for/mature-skin) — Superior fit — AED 480.00 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ae/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — AED 84.53 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/ae/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — AED 65.43 at Amazon
- SPF: [SKIN1004 MADAGASCAR CENTELLA AIR-FIT SUNCREAM PLUS](https://lovi.care/skincare/ae/p/skin1004/madagascar-centella-air-fit-suncream-plus/for/mature-skin) — Superior fit — AED 39.45 at Amazon

## Where to buy

No store in United Arab Emirates has a checked price for this product, so the page shows none.

## Ingredients

Water, Tetrahexyldecyl Ascorbate, Tocopheryl Acetate, Dimethicone, Polymethyl Methacrylate, Glyceryl Stearate, Stearic Acid, Panthenol, Aloe Barbadensis Leaf Juice, Algae Extract, Sodium Hyaluronate, Palmitoyl Hydrolyzed Wheat Protein, Cetyl Esters, Brassica Campestris Aleurites Fordi Oil Copolymer, Panicum Miliaceum Seed Extract, Phytosterols, Tocotrienols, Squalene, Rice Bran Cera, Allantoin, Avena Sativa Kernel Extract, Squalane, Pyridoxine Dipalmitate, Stearyl Glycyrrhetinate, Retinyl Palmitate, Tocopherol, Tocopheryl Linoleate, Aspergillus Aspidosperma Quebracho Ferment, Zea Mays Oil, Phenyl Trimethicone, Cyclopentasiloxane, Polysilicone-11, Lecithin, Glycerin, Cetearyl Alcohol, Carbomer, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Alcohol Denat, Sodium Hydroxide, Tromethamine, Disodium Edta, Phenoxyethanol, Ethylhexylglycerin, Potassium Sorbate, Parfum, Linalool, Geraniol, Citronellol, Beta-Carotene Ci 40800
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/skinmedica/dermal-repair-cream/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/skinmedica/dermal-repair-cream/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/skinmedica/dermal-repair-cream/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/skinmedica/dermal-repair-cream/for/mature-skin
- France: https://lovi.care/skincare/fr/p/skinmedica/dermal-repair-cream/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/skinmedica/dermal-repair-cream/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/skinmedica/dermal-repair-cream/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/skinmedica/dermal-repair-cream/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/skinmedica/dermal-repair-cream/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/skinmedica/dermal-repair-cream/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/skinmedica/dermal-repair-cream/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/skinmedica/dermal-repair-cream/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/skinmedica/dermal-repair-cream/for/mature-skin (this page)