# SKIN1004 Madagascar Centella Probio-cica Intensive Ampoule for sensitive skin

**Lovi Fit: Superior fit for sensitive skin.**
Normal Skin Fit: Superior · Effectiveness: Superior · Safety: Excellent.

Page: https://lovi.care/skincare/ae/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Arab Emirates.

Brand: [SKIN1004](https://lovi.care/skincare/ae/brands/skin1004)
Category: [Serums and treatments](https://lovi.care/skincare/ae/best/serums)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best serums for sensitive skin.

## Why this fit

- Excellent suitability for your normal skin and goals of reducing redness and irritation is provided by Lactobacillus Centella Asiatica Extract Ferment Filtrate and Centella Asiatica Extract, which offer potent anti-inflammatory and soothing benefits.
- Ceramide NP and Polyhydroxystearic Acid further enhance skin barrier resilience, ensuring your skin remains hydrated and protected.
- The product is safe for your sensitive skin, featuring soothing ingredients like Panthenol and Allantoin with no harsh or irritating components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ae/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ae/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/ae/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/ae/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/sensitive-skin): Superior (this page)
- [Acne-prone skin](https://lovi.care/skincare/ae/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/ae/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ae/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/ae/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/ae/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/oily-acne-prone-skin): High

## Key ingredients

Lactobacillus Centella Asiatica Extract Ferment Filtrate, Centella Asiatica Extract, Ceramide Np, Allantoin, Panthenol

## What the research says

- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Emulsions containing ceramides 1 and 3 improved skin hydration and reduced transepidermal water loss in sodium lauryl sulfate-irritated skin of fifteen healthy Asian women compared to a control emulsion. ([International Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18717861/))
- A lipid mixture enriched by ceramide NP with fatty acids of diverse chain lengths significantly improved skin barrier recovery rate, stratum corneum integrity, and hydration compared to a vehicle cream in healthy adult male volunteers with corticosteroid-impaired skin. ([Skin Pharmacology and Physiology, 2022](https://pubmed.ncbi.nlm.nih.gov/34348350/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))
- Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two. ([Auris, Nasus, Larynx, 2020](https://pubmed.ncbi.nlm.nih.gov/32067777/))
- A combination serum containing galactomyces ferment filtrate, dexpanthenol, and Centella asiatica effectively treated post-acne hyperpigmentation in subjects with colored skin by significantly increasing lightness scores in Fitzpatrick skin type V and reducing the melanin index in Fitzpatrick skin type IV compared to placebo. ([Skinmed, 2021](https://pubmed.ncbi.nlm.nih.gov/33938432/))

## What reviewers say

This ampoule is widely celebrated for repairing damaged skin barriers and soothing irritation, particularly for dry, sensitive, or mature skin types. Users consistently praise its rich, milky texture that provides deep hydration and a radiant glow without a sticky residue. However, it is often deemed too heavy for oily skin or humid weather. This summary is based on a very large amount of data and should be definitely taken into account.

- Liked: Soothing and calming (mostly mentioned)
- Liked: Deeply moisturizing (often mentioned)
- Liked: Luxurious texture (often mentioned)
- Liked: Barrier repair (sometimes noted)
- Disliked: Too heavy (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Dropper issues (rarely noted)
- Disliked: Scent concerns (rarely noted)

## How to apply

- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes SKIN1004 Probio-cica Intensive Ampoule one of the best fits for sensitive skin?

This product is an exceptional fit for sensitive skin because it uses fermented centella extract to powerfully calm redness and irritation. Ingredients like ceramide NP and polyhydroxystearic acid help build up your skin barrier so it stays protected, while panthenol and allantoin soothe without any harsh components.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Which ingredients make this ampoule a good fit for sensitive skin?

This ampoule is a great fit for sensitive skin because it features soothing ingredients like Lactobacillus Centella Asiatica Extract Ferment Filtrate, Centella Asiatica Extract, Panthenol, and Allantoin that help reduce redness and irritation. Ceramide NP and Polyhydroxystearic Acid also work to strengthen your skin barrier and keep it protected.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### What does Lactobacillus do for sensitive skin?

Lactobacillus helps calm sensitive skin and keeps it comfortable by reducing redness, lowering inflammation, and supporting the skin's moisture barrier. This ingredient may also improve hydration, making dry or reactive areas feel much softer and smoother over time.
Sources: [Experimental Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/31021014/), [Scientific Reports, 2023](https://pubmed.ncbi.nlm.nih.gov/37803101/)

### What does Centella Asiatica Extract do for sensitive skin?

Centella asiatica extract helps calm sensitive skin and keeps it comfortable by easing irritation and supporting moisture retention. Using this ingredient helps soothe redness and supports a healthy skin barrier with a very low likelihood of irritation.
Sources: [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40682399/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Where does this ampoule go in a skincare routine for sensitive skin?

This ampoule goes in your evening routine after your toner and before your moisturizer. Putting it in the evening keeps things simple and protects your skin around sun exposure.

### Can I use this ampoule with retinol, and in what order?

You can use this ampoule with retinol by applying the ampoule after your retinol or soothing toner to help calm and hydrate your skin. Featuring soothing ingredients like panthenol and allantoin with no harsh components, it is safe for sensitive skin and helps keep your skin barrier protected.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### How often should I use this ampoule?

Apply this treatment in your evening routine, as this timing offers extra safety around sun exposure. Centella Asiatica Extract and Panthenol help calm and hydrate sensitive skin.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Can this ampoule clog pores, cause breakouts or purging for sensitive skin?

This ampoule is unlikely to cause breakouts or clog pores for sensitive skin, as it features soothing ingredients like Panthenol and Allantoin with no harsh components. It is safe for your skin, though some reviewers occasionally mention that it feels a bit heavy.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/)

## Alternatives for sensitive skin

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/ae/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/sensitive-skin) — Superior fit — AED 347.75 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/ae/p/skinceuticals/c-e-ferulic/for/sensitive-skin) — High fit — AED 715.99 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/ae/p/neogen-dermalogy/real-vitamin-c-serum/for/sensitive-skin) — High fit — AED 89.30 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ae/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — AED 84.53 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/ae/p/clarins/soothing-toning-lotion/for/sensitive-skin) — Superior fit — AED 81.41 at Amazon
- Moisturizer with Sun Protection: [Bioderma Bioderma Photoderm Mineral SPF 50+](https://lovi.care/skincare/ae/p/bioderma/photoderm-mineral-fluide-spf50/for/sensitive-skin) — Superior fit — AED 65.10 at Amazon

## Where to buy

- Amazon.ae: AED 38.50 (https://www.amazon.ae/dp/B0BTRWGQNV?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- Lookfantastic: AED 74.00 (https://www.lookfantastic.ae/p/skin1004-madagascar-centella-probio-cica-intensive-ampoule-50ml/16858551/)
Prices checked 13 Oct – 6 Nov 2026.

## Ingredients

Lactobacillus Centella Asiatica Extract Ferment Filtrate, Centella Asiatica Extract, Ceramide Np, Polyhydroxystearic Acid, Betaine, Allantoin, Panthenol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/sensitive-skin (this page)