Prequel Barrier Therapy Skin Protectant Cream for dry skin
Oat
Multi-Ceramides
Allantoin
AdenosineSuperior
- HighDry Skin Fit
- HighEffectiveness
- ExcellentSafety
One of the best products for dry skin.
This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Excellent for your dry skin, this product's oat and ceramides deeply hydrate and support your skin barrier, while shea butter provides emollient nourishment.
- The inclusion of allantoin further soothes and protects your dry or flaky skin, enhancing overall comfort and resilience.
- This formula is exceptionally safe for your skin, containing no harsh ingredients and featuring oat and allantoin to prevent irritation.
People Say
★4.6Overall rating based on 300+ reviewsWhile the vast majority find it deeply hydrating and an excellent value for the size, a subset of users reported burning sensations or breakouts, and the product faced a significant recall in 2024 due to contamination concerns.
Highlights
Great value Often Mentioned
- “tube is huge”
- “amazing value”
- “lasts for months”
- “unbeatable price per ounce”
Non-greasy texture Often Mentioned
- “no greasy finish”
- “absorbs quickly”
- “light enough for face”
- “perfect balance of moisture”
Versatile use Sometimes Noted
- “use it head to toe”
- “great for tattoo healing”
- “replaced my face and body lotion”
- “safe for eyelids”
Availability issues Sometimes Noted
- “always sold out”
- “hard to find”
- “waiting months for restock”
- “finally back in stock”
Burning sensation Sometimes Noted
- “made my face burn”
- “caused raw red patches”
- “stung my sensitive skin”
- “irritated my neck”
Recall history Sometimes Noted
- “recalled due to bacteria”
- “caused an infection”
- “threw my tube away”
- “waiting for safe restock”
Caused breakouts Rarely Noted
- “gave me horrible acne”
- “clogged my pores”
- “caused whiteheads on chin”
- “too heavy for my acne-prone skin”
Sources: lovi.care, prequelskin.com, reddit.com, gopicky.com, skinsort.com, and more
Questions and answers
What makes Prequel Barrier Therapy Skin Protectant Cream one of the best fits for dry skin?
This cream is one of the best fits for your dry skin because its oat and multi-ceramides deeply hydrate and support your skin barrier while shea butter provides smooth nourishment. Allantoin further calms and protects flaky skin to enhance your overall comfort and resilience.
Which ingredients make this cream a good fit for dry skin?
This cream is an exceptional fit for dry skin because its oat and multi-ceramides deeply hydrate and support your skin barrier, while shea butter provides rich nourishment. Additionally, allantoin and adenosine help soothe and protect flaky skin to enhance overall comfort.
What does Oat do for dry skin?
Oat helps soothe and deeply moisturize dry skin by repairing the skin barrier and easing itch and roughness. It is unlikely to cause irritation and may significantly improve overall skin comfort.
Journal of Drugs in Dermatology, 2016Journal of Drugs in Dermatology, 2015
What do Ceramides do for dry skin?
Ceramides help keep dry skin soft by strengthening the outer barrier and locking in hydration. This improvement in barrier integrity reduces dryness and protects against irritation.
The British Journal of Dermatology, 2022Dermatologic Therapy, 2019
Where does this cream go in a skincare routine for dry skin?
This cream goes as the moisturizer step in your morning routine and your evening routine. Using a moisturizer daily helps hydrate dry skin and supports your skin barrier.
The Journal of Dermatological Treatment, 2022Scientific Reports, 2022
Can I use this cream with retinol, and in what order?
You can use this cream with retinol by applying the cream after your retinol treatment in the evening routine to help lock in moisture and soothe dryness. Using a barrier-supporting moisturizer helps improve skin comfort and reduces the irritation often caused by retinol.
How often should I use this cream?
You can use this cream daily as part of your morning and evening routine to keep dry skin hydrated and comfortable. Regular use of moisturizers with these ingredients helps improve skin barrier function and reduces dryness.
The Journal of Dermatological Treatment, 2022Scientific Reports, 2022
Can this cream clog pores, cause breakouts or purging for dry skin?
This cream is unlikely to clog pores or cause breakouts for dry skin, as its risk of causing breakouts is very low. Its rich blend of oat, multi-ceramides, and shea butter deeply hydrates and nourishes your skin without heavy oils.
Is this cream fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol. Cetyl alcohol is a fatty alcohol, which soften the skin.
What the research says
Application of Body Lotion for 5 weeks on cosmetic dry skin improved barrier properties, increased levels of cholesterol, ceramides, and long-chain fatty acids, increased beneficial skin bacteria, and enhanced microbiome functional potential compared to baseline.
Scientific Reports, 2022Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel.
Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016A repair cream containing Rhealba oat plantlets extract, l-ALA-l-GLU dipeptide, and hyaluronic acid provided immediate relief and was judged by doctors as good or very good in 96.8% of cases for wound healing in 2,363 patients following dermatological acts.
Clinical, Cosmetic and Investigational Dermatology, 2018Topically applied Avena sativa and Avena Rhealba oatmeal extracts significantly reduced skin irritation parameters including a* parameter increase and blood flow increase compared to vehicle in 12 healthy individuals subjected to the sodium lauryl sulfate irritation model.
Skin Pharmacology and Applied Skin Physiology, 2002Colloidal oat extracts diminished pro-inflammatory cytokines in vitro and colloidal oat lotion improved skin dryness, scaling, roughness, and itch intensity in healthy female subjects compared to baseline.
Journal of Drugs in Dermatology, 2015A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo.
Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment.
Aesthetic Plastic Surgery, 2018Prophylactic application of a topical scar gel containing Allium cepae extract, allantoin, and heparin significantly improves patient-assessed scar color, stiffness, and irregularity compared to no treatment in women following a cesarean section.
Journal of Drugs in Dermatology, 2014Topical adenosine treatment significantly increased the anagen hair growth rate and thick hair rate compared to placebo in Japanese women with female pattern hair loss over 12 months.
The Journal of Dermatology, 2008Topical application of a disodium adenosine monophosphate-based formulation reduced wrinkles and hyperpigmentation while improving hydration, barrier function, skin lifting, and epidermal turnover in female participants.
International Journal of Molecular Sciences, 2026Adenosine and cordycepin stimulate the Wnt/beta-catenin signaling pathway through adenosine receptor and PKA activation, promoting cell proliferation, migration, and growth factor secretion in cultured dermal fibroblasts.
International Journal of Molecular Sciences, 2021
Ingredients
Oat, Water, Carthamus Tinctorius Seed Oil, Cetyl Alcohol, Glycerin, Butyrospermum Parkii Butter, Caprylic Capric Triglyceride, Dimethicone, C10-18 Triglycerides, Allantoin, Adenosine, Cetearyl Olivate, Sorbitan Olivate, Ceramide Ap, Ceramide Eos, Ceramide Eop, Ceramide Np, Ceramide Ns, Cholesterol, Caprooyl Phytosphingosine, Caprooyl Sphingosine, Glycolipids, Sodium Stearoyl Glutamate, Behenic Acid, Ceteareth-25, Glycine Soja Sterols, Hydrogenated Palm Glycerides, Hydrogenated Palm Glycerides Kernel, Carbomer, Phenoxyethanol, Ethylhexylglycerin, Tocopheryl Acetate, Tetrasodium Glutamate Diacetate, Sodium Hydroxide
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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