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Perricone MD Rejuvenating Moisturizer for dry skin

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes

Perricone MD Rejuvenating Moisturizer

Average

  • AverageDry Skin Fit
  • AverageEffectiveness
  • HighSafety

Works for dry skin; other moisturizers fit it better.

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.

Page built Nov 8, 2026How the Fit score works

Lovi Assistant explains

  • Offers moderate suitability for your dry skin as Glycerin and Macadamia Ternifolia Seed Oil provide excellent moisturizing and barrier resilience, though it lacks more potent emollient ingredients for optimal results.
  • The presence of S-Palmitoylglutathione offers antioxidant activity, complementing the hydration benefits for dry or flaky skin.
  • The product is safe for your dry skin, containing no harsh ingredients and including soothing components like Glycerin and Macadamia Ternifolia Seed Oil.

How to apply

  • Could be used as part of your AM or PM routine. Start using it 3 times a week and work your way up to daily use.
  • Apply your moisturizer after your toner and before your sunscreen in the morning. At night, use it as the final step after your serum.
  • Gently press a small amount of the moisturizer into your skin. Avoid rubbing to keep your dry skin happy.
  • Apply the moisturizer on slightly damp skin to help lock in extra hydration. This is great for soothing dry and flaky areas .
  • Avoid the sensitive eye area and do a patch test before your first use .

People Say

★4.6Overall rating based on 1.0k+ reviews

This moisturizer is praised for its rich texture that plumps, firms, and smooths aging or dry skin without greasiness. Many users report reduced fine lines and improved radiance. Some users experienced product pilling or sensitivity to the fragrance.

Highlights

  • Deeply hydrating Often Mentioned
    • “Keeps my skin moist without the acne.”
    • “Very rich and nourishing.”
    • “Replenishes fragile skin.”
  • Improves texture Often Mentioned
    • “Skin looks smoother, with no discoloration.”
    • “Visibly plumper, firmer, and smoother.”
    • “Skin feels better, smoother and brighter.”
  • Non-greasy formula Sometimes Noted
    • “It's non greasy, absorbs right in.”
    • “Absorbs quickly without any residual grease.”
    • “Not greasy or sticky.”
  • Reduces lines Sometimes Noted
    • “Plumps my skin to reduce the look of fine lines.”
    • “Targets deep wrinkles and creases.”
    • “Saw a reduction in the appearance of fine lines.”
  • Product pilling Sometimes Noted
    • “When I try to apply my liquid makeup over it it rolls up.”
    • “It all pealed away. It looked like a snow storm.”
    • “I do not really experience pilling unless I use too much.”
  • Fragrance sensitivity Rarely Noted
    • “A few reviewers found the fragrance too strong.”
    • “Unfortunately had an allergic reaction.”
    • “Experienced minor irritation.”
  • White cast Rarely Noted
    • “Leaves this white flaky texture on my face.”
    • “Had to really blend so it didn't appear to leave a white cast.”
    • “Doesn't leave a whitecast (after 7 days).”

Sources: lovi.care, perriconemd.com, lovelyskin.com, walmart.com, ipsy.com, nordstrom.com, and more

Questions and answers

How well does Perricone MD Rejuvenating Moisturizer work for dry skin?

This moisturizer works moderately well for dry skin, as glycerin and macadamia seed oil help hydrate and support the skin barrier, though other products fit this skin type better. To achieve optimal results for dry skin, a product of this type needs more potent emollient ingredients, rich moisture-retaining agents, and soothing components to ensure deep nourishment and comfort.

Clinical, Cosmetic and Investigational Dermatology, 2017

Which ingredients make this cream a good fit for dry skin?

Glycerin and Macadamia Ternifolia Seed Oil help make this cream a good fit for dry skin by providing solid moisture and barrier support. To work best for very dry skin, a product of this type needs richer emollients and stronger moisturizing ingredients like hyaluronic acid.

Clinical, Cosmetic and Investigational Dermatology, 2017

What does Acyl-Glutathione do for dry skin?

Acyl-glutathione helps protect dry skin by boosting antioxidant defenses and supporting moisture levels. It is unlikely to irritate dry skin and may help keep it feeling soft and smooth.

The Journal of Clinical and Aesthetic Dermatology, 2025

What does Vitamin C do for dry skin?

Vitamin C helps keep dry skin hydrated and makes it feel soft and smooth. Daily use may also improve overall skin texture and brightness over time.

Photochemistry and Photobiology, 2021Skin Research and Technology, 2008

Where does it go in a skincare routine for dry skin?

This moisturizer goes in the morning routine after your hydrating toner and before your sunscreen, and in the evening routine as your final step after your treatment. It helps keep your skin soft and comfortable by providing moderate hydration and barrier support, though dry skin generally needs richer, more potent softening ingredients for optimal results.

The Journal of Dermatological Treatment, 2022Clinical, Cosmetic and Investigational Dermatology, 2017

Can I use this cream with retinol, and in what order?

You can use this cream alongside retinol by applying the retinol first and following it with this moisturizer to help keep your skin comfortable and hydrated. This type of skin needs a product packed with rich, heavy barrier-softening ingredients to achieve the best results on dry skin.

Cutis, 2006

How often should I use it?

You can use this moisturizing treatment twice a day as part of your morning and evening routine to keep your dry skin soft and hydrated. Daily application helps improve skin moisture and supports the skin barrier, though dry skin generally needs richer emollient ingredients for optimal results.

Journal of Cosmetic Dermatology, 2020Health Science Reports, 2021

Can this cream clog pores, cause breakouts or purging for dry skin?

This moisturizing treatment is unlikely to clog pores or cause breakouts for dry skin, as it contains no harsh ingredients and is generally safe for your skin type. To truly comfort dry skin, this type of product needs richer softening ingredients to keep it feeling completely smooth.

Clinical, Cosmetic and Investigational Dermatology, 2017

Can I use it around the eyes or on my body?

You can use this moisturizing treatment around your eyes and on your body, as it has a very safe profile for the skin. However, because dry skin needs stronger softening ingredients and richer moisture for optimal results, a product of this type needs more potent emollients.

Is this cream fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (parfum, citronellol, limonene, and linalool). Cetearyl alcohol is a fatty alcohol, which soften the skin.

What the research says

Why other moisturizers fit dry skin better

Ingredients

Water, Ethylhexyl Palmitate, Glycerin, Dimethicone, Cetearyl Alcohol, Glyceryl Stearate, Polysorbate 60, Palmitoyl Glycine, S-Palmitoylglutathione, Tetrahexyldecyl Ascorbate, Peg-100 Stearate, Ribose, Lactic Acid, Linum Usitatissimum Seed Oil, Macadamia Ternifolia Seed Oil, Polyglyceryl-10 Stearate, Ethylhexylglycerin, Salvia Hispanica Seed Oil, Tocopherol, Helianthus Annuus Seed Oil Sunflower Seed Oil, Rosmarinus Officinalis Leaf Extract Rosemary Leaf Extract, Tetrasodium Glutamate Diacetate, Sodium Hydroxide, Polyacrylamide, Sodium Acrylates Copolymer, Polysilicone-11, Hydrogenated Polyisobutene, C13-14 Isoparaffin, Laureth-7, Phenoxyethanol, Parfum, Citronellol, Hydroxycitronellal, Limonene, Linalool

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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How does it fit your skin?

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