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Perricone MD Rejuvenating Moisturizer for skin with dark spots

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes

Perricone MD Rejuvenating Moisturizer

Average

  • AverageNormal Skin Fit
  • AverageEffectiveness
  • HighSafety

Works for skin with dark spots; other moisturizers fit it better.

This fit is calculated for the concerns frequently associated with dark spots: hyperpigmentation, sun spots, and uneven skin tone. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.

Page built Nov 8, 2026How the Fit score works

Lovi Assistant explains

  • Offers moderate moisturizing for your normal skin due to glycerin and dimethicone, which hydrate and smooth texture, but it does not specifically target your main goal of pigmentation.
  • Tetrahexyldecyl ascorbate and macadamia ternifolia seed oil provide antioxidant activity and nourishment, offering general skincare benefits that are supportive but not optimized for your concerns.
  • The product is safe for your normal skin, with no risks of irritation from harsh ingredients and the inclusion of soothing rosemary leaf extract.

How to apply

  • Could be used as part of your AM and PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
  • Apply this moisturizer after your cleanser and toner, right before your morning SPF.
  • Gently press a small amount of the moisturizer into your skin. Avoid rubbing it too hard so it absorbs nicely.
  • For the best moisture, you can apply it when your skin is slightly damp. This helps your skin stay soft and happy.
  • Remember to avoid the eye area when applying. Always do a patch test before your first use.

People Say

★4.6Overall rating based on 1.0k+ reviews

This moisturizer is praised for its rich texture that plumps, firms, and smooths aging or dry skin without greasiness. Many users report reduced fine lines and improved radiance. Some users experienced product pilling or sensitivity to the fragrance.

Highlights

  • Deeply hydrating Often Mentioned
    • “Keeps my skin moist without the acne.”
    • “Very rich and nourishing.”
    • “Replenishes fragile skin.”
  • Improves texture Often Mentioned
    • “Skin looks smoother, with no discoloration.”
    • “Visibly plumper, firmer, and smoother.”
    • “Skin feels better, smoother and brighter.”
  • Non-greasy formula Sometimes Noted
    • “It's non greasy, absorbs right in.”
    • “Absorbs quickly without any residual grease.”
    • “Not greasy or sticky.”
  • Reduces lines Sometimes Noted
    • “Plumps my skin to reduce the look of fine lines.”
    • “Targets deep wrinkles and creases.”
    • “Saw a reduction in the appearance of fine lines.”
  • Product pilling Sometimes Noted
    • “When I try to apply my liquid makeup over it it rolls up.”
    • “It all pealed away. It looked like a snow storm.”
    • “I do not really experience pilling unless I use too much.”
  • Fragrance sensitivity Rarely Noted
    • “A few reviewers found the fragrance too strong.”
    • “Unfortunately had an allergic reaction.”
    • “Experienced minor irritation.”
  • White cast Rarely Noted
    • “Leaves this white flaky texture on my face.”
    • “Had to really blend so it didn't appear to leave a white cast.”
    • “Doesn't leave a whitecast (after 7 days).”

Sources: lovi.care, perriconemd.com, lovelyskin.com, walmart.com, ipsy.com, nordstrom.com, and more

Questions and answers

How well does Perricone MD Rejuvenating Moisturizer work for skin with dark spots?

This moisturizer works reasonably well to hydrate and smooth your skin, though it is not specifically designed to fade dark spots. A moisturizing treatment for this skin needs effective brightening ingredients alongside gentle hydrating components to successfully target pigmentation without causing irritation.

Clinical, Cosmetic and Investigational Dermatology, 2017

Which ingredients make this cream a good fit for skin with dark spots?

This cream is not an ideal fit for dark spots because it lacks targeted brightening ingredients, though it does include vitamin C and plant oils that offer general nourishment. Skin with dark spots needs effective brightening ingredients alongside soothing and moisturizing components to tackle pigmentation while keeping the skin calm and hydrated.

What does Acyl-Glutathione do for skin with dark spots?

Acyl-Glutathione helps fade dark spots and brightens your overall skin tone while smoothing out the surface. This ingredient has a safe profile and works by improving pigmentation, though individual results may vary.

The Journal of Clinical and Aesthetic Dermatology, 2025Molecules, 2026

What does Vitamin C do for skin with dark spots?

Vitamin C helps fade dark spots and brightens uneven skin tone by slowing down pigment production. Daily use also helps calm redness and protects against further sun damage.

Journal of Cosmetic Dermatology, 2023Dermatologic Surgery, 2005

Where does this cream go in a skincare routine for skin with dark spots?

This moisturizing treatment goes in the morning routine after a hydrating toner and before sunscreen, and in the evening routine after your treatment step. While it helps hydrate and smooth normal skin, it is not optimized for your dark spots, so skin with dark spots needs a dedicated brightening serum containing ingredients like vitamin C or kojic acid.

Journal of Drugs in Dermatology, 2023Journal of Cosmetic and Laser Therapy, 2012

Can I use this cream with retinol, and in what order?

You can use this cream alongside retinol, applying the retinol first and following with this moisturizer to help keep your skin soft and smooth. This product is safe for your skin with no harsh ingredients, though a moisturizer that specifically targets dark spots with brightening ingredients would work better for your main goal.

How often should I use this cream?

You can use this moisturizing treatment twice daily to keep your normal skin soft and hydrated. Skin with dark spots needs a dedicated brightening serum containing ingredients like vitamin C or niacinamide to specifically fade discoloration.

Journal of Cosmetic Dermatology, 2020Journal of Drugs in Dermatology, 2015

Can this cream clog pores, cause breakouts or purging for skin with dark spots?

This cream is unlikely to clog pores or cause breakouts on your skin, as it has a safe profile with gentle ingredients and soothing rosemary leaf extract. To better target dark spots, this skin needs dedicated brightening ingredients like vitamin C or niacinamide alongside gentle exfoliants.

Can I use this cream around the eyes or on my body?

You can use this moisturizing treatment around the eyes and on the body because it has a safe formula with soothing rosemary leaf extract and gentle hydrators like glycerin that smooth texture. However, skin with dark spots needs a product that specifically targets pigmentation with specialized brightening ingredients.

Surgical and Radiologic Anatomy, 2002

Is this cream fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (parfum, citronellol, limonene, and linalool). Cetearyl alcohol is a fatty alcohol, which soften the skin.

What the research says

Why other moisturizers fit skin with dark spots better

Ingredients

Water, Ethylhexyl Palmitate, Glycerin, Dimethicone, Cetearyl Alcohol, Glyceryl Stearate, Polysorbate 60, Palmitoyl Glycine, S-Palmitoylglutathione, Tetrahexyldecyl Ascorbate, Peg-100 Stearate, Ribose, Lactic Acid, Linum Usitatissimum Seed Oil, Macadamia Ternifolia Seed Oil, Polyglyceryl-10 Stearate, Ethylhexylglycerin, Salvia Hispanica Seed Oil, Tocopherol, Helianthus Annuus Seed Oil Sunflower Seed Oil, Rosmarinus Officinalis Leaf Extract Rosemary Leaf Extract, Tetrasodium Glutamate Diacetate, Sodium Hydroxide, Polyacrylamide, Sodium Acrylates Copolymer, Polysilicone-11, Hydrogenated Polyisobutene, C13-14 Isoparaffin, Laureth-7, Phenoxyethanol, Parfum, Citronellol, Hydroxycitronellal, Limonene, Linalool

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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