# Obagi Tretinoin Cream for oily skin

**Lovi Fit: High fit for oily skin.**
Oily Skin Fit: Superior · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/ae/p/obagi/tretinoin-cream/for/oily-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Arab Emirates.

Brand: [Obagi](https://lovi.care/skincare/ae/brands/obagi)
Category: [Serums and treatments](https://lovi.care/skincare/ae/best/serums)

This fit is calculated for the concerns frequently associated with oily skin: shine, enlarged pores, blackheads, and blemishes. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for oily skin; a few serums fit it even better.

## Why this fit

- Offers excellent treatment for acne lesions and blemishes, as tretinoin in moderate concentrations exfoliates and regulates sebum production, which is highly beneficial for your oily skin.
- The presence of stearic acid and isopropyl myristate further supports skin renewal and hydration, complementing the primary action for your skin type.
- The formulation is safe for your oily skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ae/p/obagi/tretinoin-cream/for/oily-skin): High (this page)
- [Dry skin](https://lovi.care/skincare/ae/p/obagi/tretinoin-cream/for/dry-skin): Low
- [Combination skin](https://lovi.care/skincare/ae/p/obagi/tretinoin-cream/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/ae/p/obagi/tretinoin-cream/for/sensitive-skin): Low
- [Acne-prone skin](https://lovi.care/skincare/ae/p/obagi/tretinoin-cream/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/ae/p/obagi/tretinoin-cream/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/ae/p/obagi/tretinoin-cream/for/mature-skin): Low
- [Dry sensitive skin](https://lovi.care/skincare/ae/p/obagi/tretinoin-cream/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/ae/p/obagi/tretinoin-cream/for/oily-acne-prone-skin): Average

## Key ingredients

Tretinoin, Stearic Acid, Isopropyl Myristate, Stearyl Alcohol, Xanthan Gum

## What the research says

- Tretinoin-loaded nano lipid carriers resulted in a significantly higher rate of decrease in acne lesions and greater reduction in porphyrin production compared to conventional tretinoin cream in patients with mild to moderate acne vulgaris. ([Archives of Dermatological Research, 2022](https://pubmed.ncbi.nlm.nih.gov/34146120/))
- A galenic compound containing essential oils and tretinoin demonstrated anti-acne efficacy and anti-inflammatory activity, significantly reducing papular erythema and retinoid-induced rashes compared to clindamycin-tretinoin gel in sixty volunteers over 30 days. ([Clinical, Cosmetic and Investigational Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32210603/))
- Propylene glycol increased trans epidermal water loss significantly compared to other skin penetration enhancers, while isopropyl myristate significantly increased kallikrein 5 activity when applied to human subjects. ([International Journal of Pharmaceutics, 2014](https://pubmed.ncbi.nlm.nih.gov/25305378/))
- Repeated application of concentrated water-in-oil emulsions over four weeks caused no skin irritation, positively affected skin properties, and delivered almost 50% of the applied fluorescein sodium, with isopropyl myristate showing superior penetration performance compared to liquid paraffin in healthy volunteers. ([International Journal of Pharmaceutics, 2019](https://pubmed.ncbi.nlm.nih.gov/31525444/))
- A topical xanthan gum nanogel containing gamma-oryzanol-loaded nanostructured lipid carriers and nanosized TiO2 and MBBT filters demonstrated high photoprotection with an SPF of 34 and no skin irritation or sensitization in a rat model. ([Pharmaceuticals, 2023](https://pubmed.ncbi.nlm.nih.gov/37242453/))
- Topical tretinoin improves clinical appearance of photoaging in terms of wrinkling, mottled hyperpigmentation, sallowness, and lentigines and is safe and well tolerated. ([International Journal of Women's Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35620028/))
- Topical tretinoin daily application for 10 to 12 months produced an 80 percent increase in collagen I formation in photodamaged human skin compared with a 14 percent decrease with vehicle alone. ([The New England Journal of Medicine, 1993](https://pubmed.ncbi.nlm.nih.gov/8336752/))
- Topical tretinoin precursors and tretinoin showed no significant difference in efficacy for moderate to severe facial photodamage in 20 patients, while tretinoin precursors caused erythema six times less frequently. ([JAMA Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35675051/))
- Sodium dodecyl sulfate treatment disrupts the ordered intercellular lipid lamellar structure in hairless mouse stratum corneum, and immersion in a ceramide 3, cholesterol, and stearic acid mixture successfully reorganizes this ordered lamellar structure. ([Biophysical Chemistry, 2001](https://pubmed.ncbi.nlm.nih.gov/11254216/))
- Increasing the softness of pressure-sensitive adhesives using isopropyl myristate decreased pain and stripped corneocytes during removal without significantly changing human skin dermal peeling force. ([Skin Research and Technology, 2007](https://pubmed.ncbi.nlm.nih.gov/17374065/))
- A modern cold cream formulation using a self-emulsionable excipient with isopropyl myristate shows improved preparation ease, stability, rheological qualities, and moisture and emollient power compared to traditional cerates. ([Bollettino Chimico Farmaceutico, 1996](https://pubmed.ncbi.nlm.nih.gov/8942063/))
- Biodegradable wound dressings functionalized with silver nanoparticles showed >99% pathogen growth inhibition, bactericidal effects, free radical scavenging, reduced inflammatory response in macrophages, and accelerated wound healing in animals. ([International Journal of Biological Macromolecules, 2022](https://pubmed.ncbi.nlm.nih.gov/35780920/))
- Dense chitosan-xanthan membranes associated with multipotent mesenchymal stromal cells accelerated wound healing in Wistar rats compared to untreated conditions, demonstrating safety and feasibility for dermo-epidermal wound treatment. ([Journal of Biomaterials Applications, 2015](https://pubmed.ncbi.nlm.nih.gov/25281644/))
- Glycerol crosslinked vitamin E loaded xanthan gum and gellan gum nanoemulgels scavenged 88.5% of free radicals, reduced transepidermal water loss by up to 33.3%, and improved moisture content and skin structural characteristics in a murine dry skin model. ([International Journal of Biological Macromolecules, 2025](https://pubmed.ncbi.nlm.nih.gov/41224059/))

## What reviewers say

Based on a very large amount of data, this product is highly effective for acne-prone, sun-damaged, or aging skin, significantly improving hyperpigmentation, fine lines, and skin texture for a smoother, clearer complexion. Users frequently report an adjustment period with peeling, dryness, and irritation, particularly those with sensitive or dry skin.

- Disliked: Causes skin peeling (mostly mentioned)
- Liked: Clears acne breakouts (often mentioned)
- Liked: Fades dark spots (often mentioned)
- Disliked: High price point (often mentioned)
- Liked: Improves skin texture (sometimes noted)
- Liked: Reduces fine lines (sometimes noted)
- Disliked: Initial acne purging (sometimes noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week and build up to daily use if your skin tolerates it well.
- Apply the serum after cleansing and toning, but right before your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin. Let it absorb ⏱ for a minute before applying the next product.
- Apply the serum on clean and dry skin since your skin is not sensitive and you want to target oily shine. This helps control excess oil throughout the night.
- Avoid the delicate eye area and do a patch test before using the serum for the very first time.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Obagi Tretinoin Cream a great fit for oily skin?

Obagi Tretinoin Cream is a great fit for your oily skin because it offers excellent treatment for acne lesions and blemishes, as tretinoin exfoliates and regulates oil production. The formula also supports skin renewal and hydration while remaining very safe without harsh or irritating ingredients.
Sources: [Archives of Dermatological Research, 2022](https://pubmed.ncbi.nlm.nih.gov/34146120/), [Clinical, Cosmetic and Investigational Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32210603/)

### Which ingredients make this cream a good fit for oily skin?

Obagi Tretinoin Cream is a great fit for oily skin because tretinoin helps clear breakouts by managing oil and renewing the skin. Additionally, ingredients like stearic acid and isopropyl myristate support hydration and renewal without causing irritation.
Sources: [Archives of Dermatological Research, 2022](https://pubmed.ncbi.nlm.nih.gov/34146120/), [Clinical, Cosmetic and Investigational Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32210603/)

### What does Tretinoin do for oily skin?

Tretinoin helps keep oily skin clear by reducing blemishes and clearing clogged pores. It speeds up skin renewal, which may reduce breakouts and leave your skin looking smoother over time.
Sources: [Archives of Dermatological Research, 2022](https://pubmed.ncbi.nlm.nih.gov/34146120/), [Clinical Therapeutics, 1992](https://pubmed.ncbi.nlm.nih.gov/1283729/)

### What does Stearic Acid do for oily skin?

Stearic acid helps restore and protect the natural protective barrier of oily skin when it has been stripped or disrupted by harsh treatments. This ingredient works best alongside ceramides and cholesterol to rebuild the normal structure of your skin so it feels smooth and stays balanced.
Sources: [Biophysical Chemistry, 2001](https://pubmed.ncbi.nlm.nih.gov/11254216/)

### Where does this cream go in a skincare routine for oily skin?

This cream goes in the evening routine after cleansing and before moisturizing, fitting well into an oily skin regimen. Using it at night helps avoid extra sun exposure risks while the tretinoin treats blemishes and balances oil.

### Can I use this cream with vitamin C, and in what order?

You can use this cream alongside vitamin C by applying vitamin C in the morning and this treatment at night, as using them at separate times helps prevent extra irritation on your oily skin.

### How often should I use this cream?

Use this treatment in your evening routine once a week to start, and if your skin tolerates it well and you see good results, you can carefully use it more often. Topical treatments are placed in the evening for simplicity and extra safety around sun exposure.

### Can this cream clog pores, cause breakouts or purging for oily skin?

Yes, this cream may cause initial acne purging and skin peeling while it helps clear blemishes and regulate oil on your oily skin. It is unlikely to cause other irritation since it has a very safe formula, though some temporary breakouts are common when starting out.
Sources: [Archives of Dermatological Research, 2022](https://pubmed.ncbi.nlm.nih.gov/34146120/), [Clinical, Cosmetic and Investigational Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32210603/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Stearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for oily skin

- [Clinique Fresh Pressed Daily Booster with Pure Vitamin C 10%](https://lovi.care/skincare/ae/p/clinique/fresh-pressed-daily-booster-with-pure-vitamin-c-10/for/oily-skin) — Superior fit — AED 365.22 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/ae/p/skinceuticals/c-e-ferulic/for/oily-skin) — High fit — AED 715.99 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/ae/p/neogen-dermalogy/real-vita-c-serum/for/oily-skin) — High fit — AED 89.30 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/ae/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — AED 49.95 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/ae/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — AED 49.99 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/ae/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/oily-skin) — Superior fit — AED 33.40 at Amazon

## Where to buy

No store in United Arab Emirates has a checked price for this product, so the page shows none.

## Ingredients

Tretinoin, Stearic Acid, Isopropyl Myristate, Peg-40 Stearate, Stearyl Alcohol, Xanthan Gum, Sorbic Acid, Dibutyl Hydroxy Toluene, Water
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/obagi/tretinoin-cream/for/oily-skin
- United Kingdom: https://lovi.care/skincare/uk/p/obagi/tretinoin-cream/for/oily-skin
- Ireland: https://lovi.care/skincare/ie/p/obagi/tretinoin-cream/for/oily-skin
- Germany: https://lovi.care/skincare/de/p/obagi/tretinoin-cream/for/oily-skin
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- Canada: https://lovi.care/skincare/ca/p/obagi/tretinoin-cream/for/oily-skin
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- Singapore: https://lovi.care/skincare/sg/p/obagi/tretinoin-cream/for/oily-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/obagi/tretinoin-cream/for/oily-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/obagi/tretinoin-cream/for/oily-skin (this page)