# numbuzin Goodbye Blemish Serum for acne-prone skin

**Lovi Fit: High fit for acne-prone skin.**
Combination Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/ae/p/numbuzin/goodbye-blemish-serum/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Arab Emirates.

Brand: [numbuzin](https://lovi.care/skincare/ae/brands/numbuzin)
Category: [Serums and treatments](https://lovi.care/skincare/ae/best/serums)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for acne-prone skin; a few serums fit it even better.

## Why this fit

- This serum is highly suitable for your combination skin, as niacinamide helps regulate sebum production while multiple forms of vitamin C and Hippophae Rhamnoides Extract work to brighten your skin tone and target inflammation associated with acne and blemishes.
- The inclusion of Centella Asiatica Extract and Chamomilla Recutita Flower Extract provides soothing benefits, complementing the active ingredients and enhancing overall skin comfort.
- The product has a very good safety profile, with no harsh ingredients and a focus on calming components, making it safe for your skin.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ae/p/numbuzin/goodbye-blemish-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/ae/p/numbuzin/goodbye-blemish-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/ae/p/numbuzin/goodbye-blemish-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/ae/p/numbuzin/goodbye-blemish-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/ae/p/numbuzin/goodbye-blemish-serum/for/acne-prone-skin): High (this page)
- [Skin with dark spots](https://lovi.care/skincare/ae/p/numbuzin/goodbye-blemish-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ae/p/numbuzin/goodbye-blemish-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/ae/p/numbuzin/goodbye-blemish-serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/ae/p/numbuzin/goodbye-blemish-serum/for/oily-acne-prone-skin): High

## Key ingredients

Niacinamide, Hippophae Rhamnoides Extract, Curcuma Longa Root Extract, Centella Asiatica Extract, Ascorbic Acid

## What the research says

- Topical emulsions containing Hippophae rhamnoides and Cassia fistula plant extracts significantly reduced skin sebum contents compared to placebo in patients with grade I and grade II acne vulgaris. ([Postepy Dermatologii I Alergologii, 2014](https://pubmed.ncbi.nlm.nih.gov/25254008/))
- A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of a sea buckthorn fruit extract formulation significantly reduced skin sebum secretion in 10 healthy human volunteers compared to the control base over an 8-week period. ([Journal of Pharmacy & Bioallied Sciences, 2010](https://pubmed.ncbi.nlm.nih.gov/21814424/))
- Topical application of a 5% Hippophae rhamnoides oil-in-water emulsion significantly improved skin hydration (p=0.0003) and transepidermal water loss (p=0.0087) compared to a placebo base formulation in 13 healthy male subjects over 84 days. ([Pakistan Journal of Pharmaceutical Sciences, 2014](https://pubmed.ncbi.nlm.nih.gov/25362595/))
- Sea buckthorn seed oil prevents UV-induced disturbances in redox balance and lipid metabolism in human keratinocytes and fibroblasts by reducing reactive oxygen species and lipid peroxidation products while enhancing antioxidant levels. ([Antioxidants, 2018](https://pubmed.ncbi.nlm.nih.gov/30142919/))
- Topical application of curcumin or turmeric treats various skin conditions by leveraging antioxidant, anti-inflammatory, and antimicrobial properties. ([Skin Pharmacology and Physiology, 2023](https://pubmed.ncbi.nlm.nih.gov/38008088/))
- Topical formulations of curcumin target oxidative damage and inflammation to improve wound healing in animal models. ([Drug Discovery Today, 2017](https://pubmed.ncbi.nlm.nih.gov/28711364/))
- A curcumin-loaded spanlastic anti-aging gel utilizing formula F5 incorporated into 2% HPMC E50 demonstrated sustained release action, compatibility, and the ability to penetrate skin layers to a depth of about 112.5 um without signs of irritation. ([Saudi Pharmaceutical Journal, 2024](https://pubmed.ncbi.nlm.nih.gov/38178851/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))

## What reviewers say

Users with acne-prone and sensitive skin frequently praise this serum for its lightweight, gel-like texture that effectively soothes inflammation and gradually fades post-acne hyperpigmentation. While the majority report a brighter, more even complexion without irritation, a subset of users notes that visible results require patience and consistent use over several weeks.

- Liked: Lightweight texture (mostly mentioned)
- Liked: Fades dark spots (often mentioned)
- Liked: Gentle formula (often mentioned)
- Liked: Soothing and calming (often mentioned)
- Disliked: Slow results (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Price vs size (rarely noted)

## How to apply

- Use your serum as part of your PM routine and start 3x/week before working up to daily use.
- Apply this treatment after cleansing and toner, and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the product on clean, dry skin to help manage your breakouts safely.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Numbuzin Goodbye Blemish Serum a great fit for acne-prone skin?

Numbuzin Goodbye Blemish Serum is a great fit because niacinamide helps balance oil, while vitamin C and fruit extracts target inflammation and brighten dark spots. Centella Asiatica extract and chamomile add extra comfort, and the gentle formula is unlikely to irritate your skin.
Sources: [Postepy Dermatologii I Alergologii, 2014](https://pubmed.ncbi.nlm.nih.gov/25254008/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Which ingredients make this serum a good fit for acne-prone skin?

This serum is a great fit for your acne-prone skin because niacinamide helps balance oil, while vitamin C and seabuckthorn extract target redness and dark spots. Centella asiatica and turmeric extracts also help calm irritation and keep your skin comfortable.
Sources: [Postepy Dermatologii I Alergologii, 2014](https://pubmed.ncbi.nlm.nih.gov/25254008/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### What does Niacinamide do for acne-prone skin?

Niacinamide helps acne-prone skin by reducing both inflamed and uninflamed breakouts and calming redness. It is also very helpful for keeping oily skin balanced by cutting down on excess oil production, and it is well tolerated by most people.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38299457/), [Cureus, 2024](https://pubmed.ncbi.nlm.nih.gov/38725769/)

### What does Sea Buckthorn Extract do for acne-prone skin?

Sea buckthorn extract helps balance acne-prone skin by reducing excess oil production. Clinical evaluation shows that topical emulsions containing this extract significantly decrease skin sebum levels in people with mild to moderate acne.
Sources: [Postepy Dermatologii I Alergologii, 2014](https://pubmed.ncbi.nlm.nih.gov/25254008/)

### Where does this serum go in a skincare routine for acne-prone skin?

This serum goes in the evening routine, as treatments with active ingredients are placed at night for simplicity and extra safety around sun exposure. It has a very good safety profile and is unlikely to irritate your skin.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the treatment after your cleanser and before your moisturizer, but it is best to alternate nights or use one in the morning and one at night to keep your skin calm. This helps you get the brightening and soothing benefits without overwhelming your skin with too many strong actives at once.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/)

### How often should I use this serum?

You can use Numbuzin Goodbye Blemish Serum in your evening routine, applying it after your cleansing toner and before your moisturizer. It is unlikely to irritate your acne-prone skin, as it features a gentle formula with soothing ingredients like centella asiatica and niacinamide to help calm redness and control oil.
Sources: [Postepy Dermatologii I Alergologii, 2014](https://pubmed.ncbi.nlm.nih.gov/25254008/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Can this serum clog pores, cause breakouts or purging for acne-prone skin?

This serum is unlikely to cause breakouts for acne-prone skin since it features a very safe formula centered on calming ingredients and niacinamide to help regulate oily skin. While a small number of reviewers report breakouts, the product's focus on soothing plant extracts helps keep skin comfortable.
Sources: [Postepy Dermatologii I Alergologii, 2014](https://pubmed.ncbi.nlm.nih.gov/25254008/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Is this serum fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (citral and limonene).

## Alternatives for acne-prone skin

- [Clinique Fresh Pressed Daily Booster with Pure Vitamin C 10%](https://lovi.care/skincare/ae/p/clinique/fresh-pressed-daily-booster-with-pure-vitamin-c-10/for/acne-prone-skin) — Superior fit — AED 365.22 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/ae/p/skinceuticals/c-e-ferulic/for/acne-prone-skin) — Superior fit — AED 715.99 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/ae/p/neogen-dermalogy/real-vitamin-c-serum/for/acne-prone-skin) — Superior fit — AED 89.30 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/ae/p/cerave/foaming-facial-cleanser/for/acne-prone-skin) — Superior fit — AED 49.95 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/ae/p/some-by-mi/snail-truecica-miracle-repair-toner/for/acne-prone-skin) — Superior fit — AED 49.99 at Amazon
- Moisturizer: [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/ae/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/acne-prone-skin) — Superior fit — AED 91.81 at Amazon

## Where to buy

- Amazon.ae: AED 47.08 (https://www.amazon.ae/dp/B09158RQ79?tag=lovi00-21&linkCode=osi&th=1&psc=1)
Prices checked 5 Nov 2026.

## Ingredients

Hippophae Rhamnoides Extract, Butylene Glycol, Methyl Gluceth-20, Dipropylene Glycol, Glycerin, 1,2-Hexanediol, Niacinamide, Melia Azadirachta Flower Extract, Ocimum Sanctum Leaf Extract, Melia Azadirachta Leaf Extract, Curcuma Longa Root Extract, Corallina Officinalis Extract, Lemon Peel Oil, Citrus Aurantium Dulcis Peel Oil, Citrus Aurantifolia Oil, Polygonum Cuspidatum Root Extract, Scutellaria Baicalensis Root Extract, Camellia Sinensis Leaf Extract, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Chamomilla Recutita Flower Extract Matricaria Flower Extract, Rosmarinus Officinalis Leaf Extract Rosemary Leaf Extract, Centella Asiatica Extract, Ascorbyl Glucoside, Ascorbic Acid, 3-O-Ethyl Ascorbic Acid, Panthenol, Sodium Hyaluronate, Dipotassium Glycyrrhizate, Glycereth-26, Ammonium Acryloyldimethyltaurate Vp Copolymer, Polyglyceryl-10 Laurate, Carbomer, Allantoin, Tromethamine, Water, Hydrolyzed Jojoba Esters, Disodium Edta, Citral, Limonene
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/numbuzin/goodbye-blemish-serum/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/numbuzin/goodbye-blemish-serum/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/numbuzin/goodbye-blemish-serum/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/numbuzin/goodbye-blemish-serum/for/acne-prone-skin
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- Singapore: https://lovi.care/skincare/sg/p/numbuzin/goodbye-blemish-serum/for/acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/numbuzin/goodbye-blemish-serum/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/numbuzin/goodbye-blemish-serum/for/acne-prone-skin (this page)