# NEOCUTIS Bio Serum Firm for sensitive skin

**Lovi Fit: High fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/ae/p/neocutis/bio-serum-firm/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Arab Emirates.

Brand: [NEOCUTIS](https://lovi.care/skincare/ae/brands/neocutis)
Category: [Serums and treatments](https://lovi.care/skincare/ae/best/serums)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for sensitive skin; a few serums fit it even better.

## Why this fit

- Highly suitable for your normal skin, this serum utilizes Glycerin and Sodium Hyaluronate for effective humectant action and Squalane for emollient benefits, supporting your skin's hydration needs.
- The inclusion of peptides like Tetrapeptide-21 and Palmitoyl Tripeptide-1 Acetate offers excellent firming and plumping effects, complementing the general skincare benefits for your redness and irritation.
- The formulation is safe for your sensitive skin, as it lacks harsh ingredients and contains soothing components like Glycerin and Sodium Hyaluronate.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ae/p/neocutis/bio-serum-firm/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ae/p/neocutis/bio-serum-firm/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/ae/p/neocutis/bio-serum-firm/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/ae/p/neocutis/bio-serum-firm/for/sensitive-skin): High (this page)
- [Acne-prone skin](https://lovi.care/skincare/ae/p/neocutis/bio-serum-firm/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/ae/p/neocutis/bio-serum-firm/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ae/p/neocutis/bio-serum-firm/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/ae/p/neocutis/bio-serum-firm/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/ae/p/neocutis/bio-serum-firm/for/oily-acne-prone-skin): Average

## Key ingredients

Rejuvenating Growth Factor, Peptides, Sodium Hyaluronate, Acetyl Glucosamine, Aminopropyl Ascorbyl Phosphate

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants. ([Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/))
- A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo. ([Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical 2% N-acetyl glucosamine reduced facial hyperpigmentation in an 8-week split-face clinical test, with an even greater effect observed when combined with 4% niacinamide. ([Journal of Cosmetic Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17348991/))
- N-acetyl-glucosamine-loaded nanostructured lipid carriers successfully delivered the hydrophilic agent through the skin and reduced melanin distribution in healthy volunteers. ([Advanced Pharmaceutical Bulletin, 2016](https://pubmed.ncbi.nlm.nih.gov/28101465/))
- Topical cosmetic products containing hyaluronic acid, N-acetyl glucosamine, and gamma-amino butyric acid improved skin hydration by 24.28% to 33.60%, elasticity by 11.98%, and skin lightening by 5.26% over 2 months in 20 female participants. ([Journal of Cosmetic and Laser Therapy, 2019](https://pubmed.ncbi.nlm.nih.gov/30040516/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))

## What reviewers say

Users frequently report significant improvements in skin texture and hydration, with many experiencing smoother skin and a reduction in fine lines and increased firmness within the first week. The product is also often praised for its hydrating and plumping effects, leaving skin with a dewy glow and appearing more radiant. While a substantial number of users find the anti-aging results to be worth the cost, the high price point is a commonly mentioned drawback.

- Disliked: High price (mostly mentioned)
- Liked: Hydrating and Plumping (often mentioned)
- Liked: Improves Skin Texture (often mentioned)
- Liked: Reduces Fine Lines (often mentioned)
- Liked: Fast Results (sometimes noted)
- Liked: Gentle on Skin (sometimes noted)
- Disliked: Irritation/Reactions (rarely noted)
- Disliked: Lack of Results (rarely noted)
- Disliked: Product Pilling (rarely noted)

## How to apply

- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Bio Serum Firm a great fit for sensitive skin?

Neocutis Bio Serum Firm is a great fit because it uses glycerin and sodium hyaluronate to keep skin hydrated without causing irritation. The formula is safe for sensitive skin as it lacks harsh ingredients and includes soothing components. Additionally, peptides help firm and plump the skin while complementing care for redness.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for sensitive skin?

Glycerin and Sodium Hyaluronate help keep your skin feeling hydrated and calm, while Squalane provides soothing benefits without any harsh ingredients. These components work together to support a safe and gentle experience for your sensitive skin.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Growth Factor do for sensitive skin?

Growth factor helps soothe sensitive skin and may improve skin texture and fine lines with a low risk of irritation. It supports skin healing and barrier recovery, making it a gentle option for delicate skin types.
Sources: [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37222303/), [Skin Pharmacology and Physiology, 2013](https://pubmed.ncbi.nlm.nih.gov/23108135/)

### What do Peptides do for sensitive skin?

Peptides help support the skin barrier and improve the feel of sensitive skin by encouraging firmness and a smooth look. When paired with soothing and hydrating ingredients, peptide products are generally well tolerated and unlikely to cause irritation.
Sources: [Advanced Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39783908/), [Journal of Biomedical Materials Research, 1998](https://pubmed.ncbi.nlm.nih.gov/9457557/)

### Where does this serum go in a skincare routine for sensitive skin?

This serum goes in your evening routine after your toner and before your moisturizer. Putting it at night gives you extra safety around sun exposure, and the formula is safe for sensitive skin because it lacks harsh ingredients and contains soothing components like glycerin and sodium hyaluronate.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying it after your retinol and letting it absorb, as its soothing ingredients help calm potential dryness and irritation. It is safe for sensitive skin because it lacks harsh components and relies on gentle hydrators.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### How often should I use this serum?

This serum is a great fit for your sensitive skin and is meant to be used in the evening as part of your routine. It safely helps keep your skin hydrated and smooth while firming and plumping without causing irritation.
Sources: [Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can this serum clog pores, cause breakouts or purging for sensitive skin?

This serum is unlikely to clog pores or cause breakouts on sensitive skin, as it avoids heavy, pore-clogging ingredients and features lightweight hydrating components like Glycerin and Sodium Hyaluronate. Irritation and adverse reactions are also rarely reported by reviewers, making it a safe choice for your skin type.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for sensitive skin

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/ae/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/sensitive-skin) — Superior fit — AED 347.75 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/ae/p/skinceuticals/c-e-ferulic/for/sensitive-skin) — High fit — AED 715.99 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/ae/p/neogen-dermalogy/real-vitamin-c-serum/for/sensitive-skin) — High fit — AED 89.30 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ae/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — AED 84.53 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/ae/p/clarins/soothing-toning-lotion/for/sensitive-skin) — Superior fit — AED 81.41 at Amazon
- Moisturizer with Sun Protection: [Bioderma Bioderma Photoderm Mineral SPF 50+](https://lovi.care/skincare/ae/p/bioderma/photoderm-mineral-fluide-spf50/for/sensitive-skin) — Superior fit — AED 65.10 at Amazon

## Where to buy

No store in United Arab Emirates has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Caprylic Capric Triglyceride, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Squalane, Aminopropyl Ascorbyl Phosphate, Sodium Hyaluronate, Hydrolyzed Sodium Hyaluronate, Cutaneous Lysate, Tetrapeptide-21, Palmitoyl Tripeptide-1 Acetate, Butylene Glycol, Ethylhexylglycerin, Pullulan, Acetyl Glucosamine, Ethylene Acrylic Acid Copolymer, Polysorbate 60, Proline, Arginine, Glycine, Glutamine, Chlorphenesin, Nannochloropsis Oculata Extract, Capryloyl Carnosine, Poloxamer 338, Silica, Trifluoroacetyl Tripeptide-2, Dextran, Sorbitan Isostearate, Potassium Sorbate, Sodium Benzoate, Tocopherol, Disodium Edta, Sodium Hydroxide, Phenoxyethanol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/neocutis/bio-serum-firm/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/neocutis/bio-serum-firm/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/neocutis/bio-serum-firm/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/neocutis/bio-serum-firm/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/neocutis/bio-serum-firm/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/neocutis/bio-serum-firm/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/neocutis/bio-serum-firm/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/neocutis/bio-serum-firm/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/neocutis/bio-serum-firm/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/neocutis/bio-serum-firm/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/neocutis/bio-serum-firm/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/neocutis/bio-serum-firm/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/neocutis/bio-serum-firm/for/sensitive-skin (this page)