# MISSHA Time Revolution Night Repair Ampoule 5X for dry skin

**Lovi Fit: High fit for dry skin.**
Dry Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/ae/p/missha/time-revolution-night-repair-ampoule-5x/for/dry-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Arab Emirates.

Brand: [MISSHA](https://lovi.care/skincare/ae/brands/missha)
Category: [Serums and treatments](https://lovi.care/skincare/ae/best/serums)

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for dry skin; a few serums fit it even better.

## Why this fit

- Offers excellent skin repair for your dry skin due to Bifida Lysate Ferment and Niacinamide, which enhance barrier resilience and even skin tone. Glycerin and Squalane further support your dry skin by providing essential humectant and emollient actions.
- The formula provides general hydration beneficial for dry or flaky skin, though it is not specialized for these concerns.
- The safety profile is excellent, with no risks of irritation for your dry skin due to the absence of harsh ingredients and the presence of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ae/p/missha/time-revolution-night-repair-ampoule-5x/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ae/p/missha/time-revolution-night-repair-ampoule-5x/for/dry-skin): High (this page)
- [Combination skin](https://lovi.care/skincare/ae/p/missha/time-revolution-night-repair-ampoule-5x/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/ae/p/missha/time-revolution-night-repair-ampoule-5x/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/ae/p/missha/time-revolution-night-repair-ampoule-5x/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/ae/p/missha/time-revolution-night-repair-ampoule-5x/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ae/p/missha/time-revolution-night-repair-ampoule-5x/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/ae/p/missha/time-revolution-night-repair-ampoule-5x/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/ae/p/missha/time-revolution-night-repair-ampoule-5x/for/oily-acne-prone-skin): Average

## Key ingredients

Bifida Lysate Ferment, Niacinamide, Sodium Hyaluronate, Squalane, Extreme Biome

## What the research says

- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical application of Bifida Ferment Lysate strengthens the skin barrier function by upregulating barrier and antimicrobial peptide genes, exhibiting strong antioxidant properties, and decreasing inflammatory cytokine secretion in vitro. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37218728/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))

## What reviewers say

Users consistently praise this ampoule as a powerful anti-aging treatment that delivers deep hydration and a "glass skin" glow overnight, often comparing it favorably to the much more expensive Estée Lauder Advanced Night Repair. It is particularly effective for dry, mature, and sensitive skin types, helping to smooth rough texture and plump fine lines, though a minority of users with sensitivities to fermented ingredients or essential oils experienced irritation.

- Liked: Hydration and glow (mostly mentioned)
- Liked: Estée Lauder dupe (often mentioned)
- Liked: Improves skin texture (often mentioned)
- Liked: Fast absorption (sometimes noted)
- Disliked: Scent irritation (sometimes noted)
- Disliked: Breakouts or irritation (rarely noted)
- Disliked: Opaque packaging (rarely noted)
- Disliked: Sticky finish (rarely noted)

## How to apply

- Apply this serum PM, starting 3×/week and working up to daily use as your skin adjusts.
- Place the serum after cleansing and toner, but right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on slightly damp skin to help lock in extra moisture.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes MISSHA Time Revolution Night Repair Ampoule 5X a great fit for dry skin?

MISSHA Time Revolution Night Repair Ampoule 5X is a great fit because it helps repair your skin barrier, even out skin tone, and deeply quench dryness using ingredients like Bifida Lysate Ferment, Niacinamide, Glycerin, and Squalane. It has a very safe formula that is unlikely to cause irritation while keeping dry skin soft and smooth.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### Which ingredients make this serum a good fit for dry skin?

Bifida Lysate Ferment and Niacinamide make this serum a great fit by repairing your dry skin and strengthening its barrier. Glycerin and Squalane further help by drawing in moisture and keeping your skin soft and smooth.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### What does Bifida Ferment Lysate do for dry skin?

Bifida Ferment Lysate helps dry skin by strengthening the skin barrier and keeping it well hydrated. It also helps calm irritation and protects against everyday stress.
Sources: [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37218728/), [Scientific Reports, 2023](https://pubmed.ncbi.nlm.nih.gov/37803101/)

### What does Niacinamide do for dry skin?

Niacinamide helps dry skin by strengthening the skin barrier, increasing hydration, and reducing water loss. It supports ceramide production and helps keep the surface smooth and calm. This ingredient tends to be very well tolerated and is unlikely to irritate dry skin.
Sources: [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/), [Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/42108609/)

### Where does this serum go in a skincare routine for dry skin?

This treatment goes in your evening routine after cleansing and before your moisturizer. Putting it in the evening keeps things simple and adds safety around sun exposure.

### Can I use this serum with retinol, and in what order?

You can use this treatment with retinol by applying this product first to keep your dry skin calm and hydrated. It is unlikely to cause irritation and may help reduce the discomfort often caused by retinoids.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/)

### How often should I use this serum?

This serum is a great fit to use in the evening as part of your routine for dry skin. It helps repair your skin barrier and provides essential hydration with a very low likelihood of irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/36798538/), [Facial Plastic Surgery, 2014](https://pubmed.ncbi.nlm.nih.gov/24488631/)

### Can this serum clog pores, cause breakouts or purging for dry skin?

This serum is unlikely to cause breakouts or irritation for your dry skin, as it contains soothing components and lacks harsh ingredients. Reviewers report a low likelihood of breakouts, and the formula is safe and gentle for everyday use.

### Is this serum fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (limonene).

## Alternatives for dry skin

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/ae/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/dry-skin) — Superior fit — AED 347.75 at Amazon
- [ma:nyo Bifida Biome Complex Ampoule](https://lovi.care/skincare/ae/p/ma-nyo/bifida-biome-complex-ampoule/for/dry-skin) — Superior fit — AED 99.12 at Amazon
- [KraveBeauty Great Barrier Relief](https://lovi.care/skincare/ae/p/kravebeauty/great-barrier-relief/for/dry-skin) — Superior fit — AED 164.35 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/ae/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — AED 32.95 at Amazon
- Moisturizer: [SKIN1004 Madagascar Centella Probio-Cica Enrich Cream](https://lovi.care/skincare/ae/p/skin1004/madagascar-centella-probio-cica-enrich-cream/for/dry-skin) — Superior fit — AED 34.80 at Amazon
- SPF: [Dr.G Green Mild Up Sun+](https://lovi.care/skincare/ae/p/dr-g/green-mild-up-sun/for/dry-skin) — Superior fit — AED 81.00 at Amazon

## Where to buy

- Amazon.ae: AED 87.50 (https://www.amazon.ae/dp/B09648RPKJ?tag=lovi00-21&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Bifida Lysate Ferment, Butylene Glycol, Glycerin, Propanediol, Betaine, Water, Niacinamide, Pentylene Glycol, 1,2-Hexanediol, Diethoxyethyl Succinate, Chondrus Crispus Extract, Squalane, Panthenol, Polyglyceryl-10 Laurate, Saccharum Officinarum Extract, Hydrogenated Lecithin, Carbomer, Tromethamine, Xanthan Gum, Polyquaternium-51, Ethylhexylglycerin, Adenosine, Dextrin, Theobroma Cacao Extract, Bergamot Oil Fruit, Disodium Edta, Sodium Hyaluronate, Lactobacillus Ferment, Lactobacillus Lysate Ferment, Bifida Ferment Filtrate, Lactobacillus Acerola Cherry Ferment, Lactobacillus Punica Granatum Extract Fruit Ferment, Lactobacillus Soybean Extract Ferment, Lactococcus Ferment, Lactococcus Lysate Ferment, Leuconostoc Radish Root Ferment Filtrate, Pelargonium Graveolens Oil Flower, Beta Vulgaris Root Extract, Brassica Oleracea Capitata Leaf Extract, Daucus Carota Sativa Root Extract Carrot Root Extract, Solanum Melongena Fruit Extract, Blueberry Fruit Extract, Helianthus Annuus Seed Oil Sunflower Seed Oil, Citrus Aurantium Dulcis Peel Oil, Lavandula Angustifolia Oil Lavender Oil, Lupinus Albus Seed Extract, Aspergillus Ferment, Swiftlet Nest Extract, Anthemis Nobilis Oil Flower, Sandalwood Oil, Tocopherol, Ceramide Np, Cholesterol, Limonene
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/missha/time-revolution-night-repair-ampoule-5x/for/dry-skin
- United Kingdom: https://lovi.care/skincare/uk/p/missha/time-revolution-night-repair-ampoule-5x/for/dry-skin
- Ireland: https://lovi.care/skincare/ie/p/missha/time-revolution-night-repair-ampoule-5x/for/dry-skin
- Germany: https://lovi.care/skincare/de/p/missha/time-revolution-night-repair-ampoule-5x/for/dry-skin
- France: https://lovi.care/skincare/fr/p/missha/time-revolution-night-repair-ampoule-5x/for/dry-skin
- Italy: https://lovi.care/skincare/it/p/missha/time-revolution-night-repair-ampoule-5x/for/dry-skin
- Netherlands: https://lovi.care/skincare/nl/p/missha/time-revolution-night-repair-ampoule-5x/for/dry-skin
- Spain: https://lovi.care/skincare/es/p/missha/time-revolution-night-repair-ampoule-5x/for/dry-skin
- Canada: https://lovi.care/skincare/ca/p/missha/time-revolution-night-repair-ampoule-5x/for/dry-skin
- Australia: https://lovi.care/skincare/au/p/missha/time-revolution-night-repair-ampoule-5x/for/dry-skin
- Singapore: https://lovi.care/skincare/sg/p/missha/time-revolution-night-repair-ampoule-5x/for/dry-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/missha/time-revolution-night-repair-ampoule-5x/for/dry-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/missha/time-revolution-night-repair-ampoule-5x/for/dry-skin (this page)