# MISSHA Time Revolution Night Repair Ampoule 5X for dry sensitive skin

**Lovi Fit: High fit for dry sensitive skin.**
Dry Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/ae/p/missha/time-revolution-night-repair-ampoule-5x/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Arab Emirates.

Brand: [MISSHA](https://lovi.care/skincare/ae/brands/missha)
Category: [Serums and treatments](https://lovi.care/skincare/ae/best/serums)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for dry sensitive skin; a few serums fit it even better.

## Why this fit

- This product offers excellent skin repair for your dry and sensitive skin, as Bifida Lysate Ferment and Niacinamide work to enhance barrier resilience and even skin tone. Glycerin and Panthenol provide moderate hydration, addressing dryness and flakiness effectively.
- The inclusion of Squalane and Sodium Hyaluronate further supports barrier repair and offers additional humectant benefits, making it highly suitable for your dry skin type.
- The formulation is safe for your skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ae/p/missha/time-revolution-night-repair-ampoule-5x/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ae/p/missha/time-revolution-night-repair-ampoule-5x/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/ae/p/missha/time-revolution-night-repair-ampoule-5x/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/ae/p/missha/time-revolution-night-repair-ampoule-5x/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/ae/p/missha/time-revolution-night-repair-ampoule-5x/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/ae/p/missha/time-revolution-night-repair-ampoule-5x/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ae/p/missha/time-revolution-night-repair-ampoule-5x/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/ae/p/missha/time-revolution-night-repair-ampoule-5x/for/dry-sensitive-skin): High (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/ae/p/missha/time-revolution-night-repair-ampoule-5x/for/oily-acne-prone-skin): Average

## Key ingredients

Bifida Lysate Ferment, Niacinamide, Sodium Hyaluronate, Squalane, Extreme Biome

## What the research says

- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- Hyaluronic acid extracts are safe and efficacious products for skin repair when used in tissue regeneration alone or in combination with herbal or Western medicine. ([Journal of Pharmacy & Pharmaceutical Sciences, 2015](https://pubmed.ncbi.nlm.nih.gov/25877441/))
- Application of squalene/phosphotungstate calcium nanowires (Sql/PWC) oleogel on UVB-irradiated skin decreased epidermal thickness, increased dermal thickness, and promoted the expression of elastin, collagen, and skin barrier markers through antioxidant and anti-inflammatory activities. ([Journal of Nanobiotechnology, 2025](https://pubmed.ncbi.nlm.nih.gov/40001122/))
- Topical application of Bifida Ferment Lysate strengthens the skin barrier function by upregulating barrier and antimicrobial peptide genes, exhibiting strong antioxidant properties, and decreasing inflammatory cytokine secretion in vitro. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37218728/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))

## What reviewers say

Users consistently praise this ampoule as a powerful anti-aging treatment that delivers deep hydration and a "glass skin" glow overnight, often comparing it favorably to the much more expensive Estée Lauder Advanced Night Repair. It is particularly effective for dry, mature, and sensitive skin types, helping to smooth rough texture and plump fine lines, though a minority of users with sensitivities to fermented ingredients or essential oils experienced irritation.

- Liked: Hydration and glow (mostly mentioned)
- Liked: Estée Lauder dupe (often mentioned)
- Liked: Improves skin texture (often mentioned)
- Liked: Fast absorption (sometimes noted)
- Disliked: Scent irritation (sometimes noted)
- Disliked: Breakouts or irritation (rarely noted)
- Disliked: Opaque packaging (rarely noted)
- Disliked: Sticky finish (rarely noted)

## How to apply

- Use this PM routine for your evening skincare. Start using the serum 3 times a week and increase to daily use if your skin feels comfortable.
- Apply the serum after cleansing and toner, but right before your moisturizer. This step locks in deep hydration for dry skin.
- Gently press 2-3 drops of the serum into your skin using your palms. Let it absorb completely for a minute ⏱ before applying your next product.
- Since your skin is sensitive, apply the serum on completely dry skin for better tolerance and less irritation.
- Avoid the sensitive eye area during application. Always do a patch test before your first use to ensure your skin reacts well.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes MISSHA Time Revolution Ampoule 5X a great fit for dry sensitive skin?

This treatment is a great fit because ingredients like glycerin, panthenol, squalane, and sodium hyaluronate soothe dryness and flakiness while keeping your skin hydrated. It also helps repair your skin barrier and even out your skin tone with bifida lysate ferment and niacinamide, and it is very safe for sensitive skin without harsh or prohibited ingredients.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Which ingredients make this serum a good fit for dry sensitive skin?

Bifida Lysate Ferment and Niacinamide help strengthen your skin barrier, while Glycerin, Panthenol, Squalane, and Sodium Hyaluronate provide essential moisture to soothe dryness and flakiness. These ingredients work safely together to keep dry and sensitive skin calm and smooth.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### What does Bifida Ferment Lysate do for dry sensitive skin?

Bifida Ferment Lysate helps soothe dry sensitive skin by calming irritation and keeping moisture locked in. It strengthens your skin barrier so it stays soft and smooth against everyday stress. Using a product with this ingredient may also lower redness and keep your skin comfortable.
Sources: [Scientific Reports, 2023](https://pubmed.ncbi.nlm.nih.gov/37803101/), [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37218728/)

### What does Niacinamide do for dry sensitive skin?

Niacinamide helps dry sensitive skin by calming irritation and keeping moisture locked in so your face feels soft and smooth. It works to build up your skin barrier and calm redness while being very gentle and unlikely to cause irritation.
Sources: [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/), [International Journal of Pharmaceutics, 2013](https://pubmed.ncbi.nlm.nih.gov/23220080/)

### Where does this serum go in a skincare routine for dry sensitive skin?

This serum goes in your evening routine as a treatment step after your soothing toner and before your moisturizer. Using treatments in the evening helps keep things simple and provides extra safety around sun exposure.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying it as your treatment step in the evening routine after cleansing and toning, and before your moisturizer. It helps soothe dryness and strengthen your skin, and is unlikely to cause irritation.

### How often should I use this serum?

You can use this treatment in your evening routine. Using it daily helps address dryness and flakiness while keeping your skin calm.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Can this serum clog pores, cause breakouts or purging for dry sensitive skin?

This serum is unlikely to cause breakouts or clogged pores for dry sensitive skin, as it has a very low likelihood of causing irritation or breakouts according to reviews. Its gentle ingredients like Squalane and Sodium Hyaluronate help keep your skin smooth and calm without heavy residue.
Sources: [Journal of Pharmacy & Pharmaceutical Sciences, 2015](https://pubmed.ncbi.nlm.nih.gov/25877441/)

### Is this serum fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (limonene).

## Alternatives for dry sensitive skin

- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/ae/p/skinceuticals/c-e-ferulic/for/dry-sensitive-skin) — Superior fit — AED 715.99 at Amazon
- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/ae/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/dry-sensitive-skin) — Superior fit — AED 347.75 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/ae/p/augustinus-bader/the-serum/for/dry-sensitive-skin) — Superior fit — AED 1,348.00 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/ae/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — AED 32.95 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/ae/p/clarins/soothing-toning-lotion/for/dry-sensitive-skin) — Superior fit — AED 81.41 at Amazon
- Moisturizer with Sun Protection: [Dr.G Green Mild Up Sun+](https://lovi.care/skincare/ae/p/dr-g/green-mild-up-sun/for/dry-sensitive-skin) — Superior fit — AED 81.00 at Amazon

## Where to buy

- Amazon.ae: AED 87.50 (https://www.amazon.ae/dp/B09648RPKJ?tag=lovi00-21&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Bifida Lysate Ferment, Butylene Glycol, Glycerin, Propanediol, Betaine, Water, Niacinamide, Pentylene Glycol, 1,2-Hexanediol, Diethoxyethyl Succinate, Chondrus Crispus Extract, Squalane, Panthenol, Polyglyceryl-10 Laurate, Saccharum Officinarum Extract, Hydrogenated Lecithin, Carbomer, Tromethamine, Xanthan Gum, Polyquaternium-51, Ethylhexylglycerin, Adenosine, Dextrin, Theobroma Cacao Extract, Bergamot Oil Fruit, Disodium Edta, Sodium Hyaluronate, Lactobacillus Ferment, Lactobacillus Lysate Ferment, Bifida Ferment Filtrate, Lactobacillus Acerola Cherry Ferment, Lactobacillus Punica Granatum Extract Fruit Ferment, Lactobacillus Soybean Extract Ferment, Lactococcus Ferment, Lactococcus Lysate Ferment, Leuconostoc Radish Root Ferment Filtrate, Pelargonium Graveolens Oil Flower, Beta Vulgaris Root Extract, Brassica Oleracea Capitata Leaf Extract, Daucus Carota Sativa Root Extract Carrot Root Extract, Solanum Melongena Fruit Extract, Blueberry Fruit Extract, Helianthus Annuus Seed Oil Sunflower Seed Oil, Citrus Aurantium Dulcis Peel Oil, Lavandula Angustifolia Oil Lavender Oil, Lupinus Albus Seed Extract, Aspergillus Ferment, Swiftlet Nest Extract, Anthemis Nobilis Oil Flower, Sandalwood Oil, Tocopherol, Ceramide Np, Cholesterol, Limonene
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/missha/time-revolution-night-repair-ampoule-5x/for/dry-sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/missha/time-revolution-night-repair-ampoule-5x/for/dry-sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/missha/time-revolution-night-repair-ampoule-5x/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/missha/time-revolution-night-repair-ampoule-5x/for/dry-sensitive-skin
- France: https://lovi.care/skincare/fr/p/missha/time-revolution-night-repair-ampoule-5x/for/dry-sensitive-skin
- Italy: https://lovi.care/skincare/it/p/missha/time-revolution-night-repair-ampoule-5x/for/dry-sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/missha/time-revolution-night-repair-ampoule-5x/for/dry-sensitive-skin
- Spain: https://lovi.care/skincare/es/p/missha/time-revolution-night-repair-ampoule-5x/for/dry-sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/missha/time-revolution-night-repair-ampoule-5x/for/dry-sensitive-skin
- Australia: https://lovi.care/skincare/au/p/missha/time-revolution-night-repair-ampoule-5x/for/dry-sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/missha/time-revolution-night-repair-ampoule-5x/for/dry-sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/missha/time-revolution-night-repair-ampoule-5x/for/dry-sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/missha/time-revolution-night-repair-ampoule-5x/for/dry-sensitive-skin (this page)