# MEDIHEAL Madecassoside Essential Mask for acne-prone skin

**Lovi Fit: High fit for acne-prone skin.**
Combination Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/ae/p/mediheal/madecassoside-essential-mask/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Arab Emirates.

Brand: [MEDIHEAL](https://lovi.care/skincare/ae/brands/mediheal)
Category: [Face masks](https://lovi.care/skincare/ae/best/face-masks)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best nourishing masks for acne-prone skin.

## Why this fit

- Offers high suitability for your combination skin, as niacinamide helps regulate oil production while madecassoside and centella asiatica extract provide anti-inflammatory and barrier-strengthening benefits for your acne-prone skin.
- The formula also includes soothing botanicals like chamomile and purslane extracts, which further calm irritation and support skin repair.
- The safety profile is excellent, with no harsh ingredients and a focus on soothing components that minimize the risk of irritation for your skin.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ae/p/mediheal/madecassoside-essential-mask/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ae/p/mediheal/madecassoside-essential-mask/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/ae/p/mediheal/madecassoside-essential-mask/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/ae/p/mediheal/madecassoside-essential-mask/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/ae/p/mediheal/madecassoside-essential-mask/for/acne-prone-skin): High (this page)
- [Skin with dark spots](https://lovi.care/skincare/ae/p/mediheal/madecassoside-essential-mask/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ae/p/mediheal/madecassoside-essential-mask/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/ae/p/mediheal/madecassoside-essential-mask/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/ae/p/mediheal/madecassoside-essential-mask/for/oily-acne-prone-skin): High

## Key ingredients

Madecassoside, Niacinamide, Centella Asiatica Extract, Aloe Barbadensis Leaf Juice, Resveratrol

## What the research says

- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical aloe vera gel significantly accelerated split-thickness skin graft donor-site healing compared to placebo in 12 patients, but showed no significant difference in pain relief. ([Plastic and Reconstructive Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29649056/))
- Topical application of Aloe vera cream reduced postoperative pain at rest and during defecation, accelerated wound healing at two weeks, and decreased analgesic requirements in patients after open hemorrhoidectomy compared to placebo. ([Journal of Alternative and Complementary Medicine, 2010](https://pubmed.ncbi.nlm.nih.gov/20569031/))
- Formulations containing 0.10%, 0.25%, and 0.50% freeze-dried Aloe vera extract increased stratum corneum water content compared with the vehicle in 20 female subjects, while transepidermal water loss was not modified. ([Skin Research and Technology, 2006](https://pubmed.ncbi.nlm.nih.gov/17026654/))
- Topical CE Ferulic plus resveratrol BE serum following ablative fractional CO2 laser treatment reduced erythema index (308.9 vs. 325.3), shortened complete scabbing detachment time (6.0 vs. 6.5 days), decreased melanin index (-7.4% vs. +0.2%), and improved skin hydration compared to normal saline in 51 Chinese patients. ([Journal of the European Academy of Dermatology and Venereology, 2024](https://pubmed.ncbi.nlm.nih.gov/38828801/))
- Topical treatment with a combination of pyridine-2, 4-dicarboxylic acid diethyl ester and resveratrol significantly increased hair density in 79 Caucasian female subjects starting from 1.5 months compared to baseline. ([International Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/31960447/))
- A nighttime topical antioxidant containing resveratrol, baicalin, and vitamin E significantly improved fine lines, wrinkles, firmness, elasticity, laxity, hyperpigmentation, radiance, roughness, and dermal thickness in subjects with mild to moderately photodamaged skin over 12 weeks. ([Journal of Drugs in Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/25607790/))

## What reviewers say

Based on a very large amount of data, users with sensitive, acne-prone, and dehydrated skin widely praise this mask for its immediate ability to soothe redness and cool heated skin. It is highly effective at calming active breakouts and hydrating the skin barrier, though fading older acne scars requires consistent, long-term use.

- Liked: Soothes redness (mostly mentioned)
- Liked: Deeply hydrating (often mentioned)
- Liked: Excellent sheet fit (often mentioned)
- Liked: Generous essence (sometimes noted)
- Liked: Helps blemishes (sometimes noted)
- Disliked: Sticky after-feel (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Herbal scent (rarely noted)
- Disliked: Slow scar results (rarely noted)

## How to apply

- Could be used as part of your PM routine. Start using your sheet mask 3 times a week, and build up to daily use if your skin likes it.
- Apply your sheet mask after cleansing and toning, but before putting on your moisturizer. Relax with it on for ten to fifteen minutes.
- Take the sheet mask out and gently smooth it over your face so it fits well. Pat any leftover essence into your skin without rubbing.
- Put the sheet mask on clean and dry skin for the best comfort. This helps your pores take in all the good ingredients.
- Avoid getting the product too close to your sensitive eye area. Do a small patch test before your very first use to stay safe.
- Video: https://storage.pora.ai/cf9cbc1593b43309df7ca9cfe4fbbdae.mp4

## Questions and answers

### What makes MEDIHEAL Madecassoside Essential Mask a great fit for acne-prone skin?

This mask is a great fit because niacinamide helps balance oil while madecassoside and centella asiatica calm redness and strengthen your skin barrier. Soothing ingredients like aloe vera and chamomile further help reduce irritation and support healing without harsh components.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Which ingredients make this mask a good fit for acne-prone skin?

This mask is a great fit for your acne-prone skin because it contains niacinamide, madecassoside, and centella asiatica extract, which help control oil and calm redness. These soothing ingredients work together to calm irritation and support skin repair with a very low risk of irritation.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### What does Madecassoside do for acne-prone skin?

Madecassoside helps acne-prone skin by calming redness, reducing acne breakouts, and repairing the skin barrier to keep it healthy. It may also lower water loss and soothe irritation when used consistently in your routine.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Bioengineering, 2025](https://pubmed.ncbi.nlm.nih.gov/41007180/)

### What does Niacinamide do for acne-prone skin?

Niacinamide helps acne-prone skin by reducing both inflamed and uninflamed breakouts and calming redness. It is also very helpful for keeping oily skin balanced by cutting down on excess oil production, and it is well tolerated by most people.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38299457/), [Cureus, 2024](https://pubmed.ncbi.nlm.nih.gov/38725769/)

### Where does this mask go in a skincare routine for acne-prone skin?

This nourishing mask is a great fit for your acne-prone skin because niacinamide helps balance oil while madecassoside and centella asiatica calm redness and strengthen your skin barrier. The gentle formula has an excellent safety profile, using soothing botanicals like aloe and chamomile that are unlikely to cause irritation.
Sources: [International Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/31461548/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### Can I use this mask with retinol, and in what order?

Yes, you can use this mask with retinol by applying the mask after your retinol treatment to help calm the skin. The soothing ingredients in this formula are very safe and are unlikely to cause irritation when combined with active treatments.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### How often should I use this mask?

This nourishing mask is a great fit for your acne-prone skin and can be used weekly as part of your routine. It helps calm irritation and supports skin repair with soothing botanicals and madecassoside, with an excellent safety profile that minimizes the risk of irritation.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/)

### Can this mask clog pores, cause breakouts or purging for acne-prone skin?

This mask is a great fit for acne-prone skin because niacinamide helps balance oil while madecassoside and centella extract calm redness and irritation. Reviewers rarely report breakouts, and the formula has an excellent safety profile with soothing ingredients that minimize the risk of clogged pores.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Is this mask fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for acne-prone skin

- [Mediheal Watermide Essential Mask](https://lovi.care/skincare/ae/p/mediheal/watermide-essential-mask/for/acne-prone-skin) — High fit — AED 65.00 at Amazon
- [Anua Heartleaf 77% Soothing Sheet Mask](https://lovi.care/skincare/ae/p/anua/heartleaf-77-soothing-sheet-mask/for/acne-prone-skin) — High fit — AED 97.63 at Amazon
- [ROUND LAB Pine Calming Cica Mask](https://lovi.care/skincare/ae/p/round-lab/pine-calming-cica-mask/for/acne-prone-skin) — High fit — AED 108.37 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/ae/p/cerave/foaming-facial-cleanser/for/acne-prone-skin) — Superior fit — AED 49.95 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/ae/p/some-by-mi/snail-truecica-miracle-repair-toner/for/acne-prone-skin) — Superior fit — AED 49.99 at Amazon
- Moisturizer: [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/ae/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/acne-prone-skin) — Superior fit — AED 91.81 at Amazon

## Where to buy

- Amazon.ae: AED 121.00 (https://www.amazon.ae/dp/B0DJ1D917P?tag=lovi00-21&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, Niacinamide, Propanediol, Dipropylene Glycol, 1,2-Hexanediol, Hydroxyacetophenone, Trehalose, Glycerin, Sodium Acrylic Acid Ma Copolymer, Butylene Glycol, Disodium Edta, Carbomer, Arginine, Octyldodeceth-16, Xanthan Gum, Caprylyl Glycol, Glycine, Glutamic Acid, Centella Asiatica Extract, Madecassoside, Aspartic Acid, Anthemis Nobilis Flower Extract, Portulaca Oleracea Extract, Gluconolactone, Sodium Polyacrylate, Sodium Chloride, Resveratrol, Centella Asiatica Stem Extract Flower Leaf, Centella Asiatica Leaf Extract, Centella Asiatica Root Extract, Saccharomyces Ferment, Histidine, Serine, Alanine, Threonine, Proline, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Asiaticoside, Magnesium Chloride, Calcium Chloride, Aloe Barbadensis Leaf Juice, Asiatic Acid, Madecassic Acid
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/mediheal/madecassoside-essential-mask/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/mediheal/madecassoside-essential-mask/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/mediheal/madecassoside-essential-mask/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/mediheal/madecassoside-essential-mask/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/mediheal/madecassoside-essential-mask/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/mediheal/madecassoside-essential-mask/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/mediheal/madecassoside-essential-mask/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/mediheal/madecassoside-essential-mask/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/mediheal/madecassoside-essential-mask/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/mediheal/madecassoside-essential-mask/for/acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/mediheal/madecassoside-essential-mask/for/acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/mediheal/madecassoside-essential-mask/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/mediheal/madecassoside-essential-mask/for/acne-prone-skin (this page)