# Medicube Triple Collagen Serum 4.0 for oily skin

**Lovi Fit: Average fit for oily skin.**
Oily Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/ae/p/medicube/triple-collagen-serum-4-0/for/oily-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Arab Emirates.

Brand: [Medicube](https://lovi.care/skincare/ae/brands/medicube)
Category: [Serums and treatments](https://lovi.care/skincare/ae/best/serums)

This fit is calculated for the concerns frequently associated with oily skin: shine, enlarged pores, blackheads, and blemishes. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily skin; other serums fit it better.

## Why this fit

- Offers moderate plumping and firming benefits for your oily skin due to the inclusion of multiple collagen types and sodium hyaluronate, which support the extracellular matrix and hydration.
- While niacinamide aids in seboregulation, the formula lacks specialized ingredients to directly address your primary concern of reducing oily shine.
- The product is safe for your oily skin, with no risks of irritation from harsh ingredients and the presence of soothing components like glycerin.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ae/p/medicube/triple-collagen-serum-4-0/for/oily-skin): Average (this page)
- [Dry skin](https://lovi.care/skincare/ae/p/medicube/triple-collagen-serum-4-0/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/ae/p/medicube/triple-collagen-serum-4-0/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/ae/p/medicube/triple-collagen-serum-4-0/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/ae/p/medicube/triple-collagen-serum-4-0/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/ae/p/medicube/triple-collagen-serum-4-0/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/ae/p/medicube/triple-collagen-serum-4-0/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/ae/p/medicube/triple-collagen-serum-4-0/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/ae/p/medicube/triple-collagen-serum-4-0/for/oily-acne-prone-skin): Average

## Key ingredients

Collagen Extract, Sodium Hyaluronate, Niacinamide, Adenosine, Glycerin

## What the research says

- Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/))
- Both oral and topical collagen supplements help delay the skin aging process by improving moisture, elasticity, and hydration, with no differences arising between the two types of collagen. ([Dermatology Practical & Conceptual, 2022](https://pubmed.ncbi.nlm.nih.gov/35223163/))
- Hyaluronic acid extracts are safe and efficacious products for skin repair when used in tissue regeneration alone or in combination with herbal or Western medicine. ([Journal of Pharmacy & Pharmaceutical Sciences, 2015](https://pubmed.ncbi.nlm.nih.gov/25877441/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35818134/))
- Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks. ([International Journal of Molecular Sciences, 2022](https://pubmed.ncbi.nlm.nih.gov/35163025/))
- Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers. ([Marine Drugs, 2023](https://pubmed.ncbi.nlm.nih.gov/36827098/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical adenosine treatment significantly increased the anagen hair growth rate and thick hair rate compared to placebo in Japanese women with female pattern hair loss over 12 months. ([The Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/19239555/))
- Topical application of a disodium adenosine monophosphate-based formulation reduced wrinkles and hyperpigmentation while improving hydration, barrier function, skin lifting, and epidermal turnover in female participants. ([International Journal of Molecular Sciences, 2026](https://pubmed.ncbi.nlm.nih.gov/42278371/))
- Adenosine and cordycepin stimulate the Wnt/beta-catenin signaling pathway through adenosine receptor and PKA activation, promoting cell proliferation, migration, and growth factor secretion in cultured dermal fibroblasts. ([International Journal of Molecular Sciences, 2021](https://pubmed.ncbi.nlm.nih.gov/34070360/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))

## Why other serums fit oily skin better

- A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/))
- Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo. ([BioMed Research International, 2022](https://pubmed.ncbi.nlm.nih.gov/35342760/))

## What reviewers say

Users consistently praise this serum for delivering a "glass skin" finish and deep hydration, making it a favorite for those with dry, dull, or mature skin. While the plumping and glow-boosting effects are widely celebrated, some users with oily or sensitive skin find the formula slightly sticky or the fragrance too strong.

- Liked: Glass skin glow (mostly mentioned)
- Liked: Deep hydration (often mentioned)
- Liked: Makeup compatibility (sometimes noted)
- Liked: Silky texture (sometimes noted)
- Disliked: Added fragrance (sometimes noted)
- Disliked: Sticky or heavy (sometimes noted)
- Disliked: Packaging issues (rarely noted)
- Disliked: Price vs. quantity (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week and build up to daily use if your skin tolerates it well.
- Apply the serum after cleansing and toning, but right before your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin. Let it absorb ⏱ for a minute before applying the next product.
- Apply the serum on clean and dry skin since your skin is not sensitive and you want to target oily shine. This helps control excess oil throughout the night.
- Avoid the delicate eye area and do a patch test before using the serum for the very first time.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Medicube Triple Collagen Serum work for oily skin?

This serum works moderately well for oily skin by offering nice plumping and hydration, but it lacks the specialized ingredients needed to reduce oily shine. To truly thrive, oily skin needs targeted ingredients like niacinamide and zinc to control excess oil and manage enlarged pores.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Dermatology Practical & Conceptual, 2022](https://pubmed.ncbi.nlm.nih.gov/35223163/)

### Which ingredients make this serum a good fit for oily skin?

Niacinamide, sodium hyaluronate, and glycerin make this serum a fit for oily skin by helping control sebum while providing gentle hydration. To work best for oily skin, this type of product needs ingredients like niacinamide and zinc PCA to manage excess shine and pores, alongside light hydrators and soothing extracts.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Collagen Extract do for oily skin?

Collagen Extract is suitable for oily skin because it helps support skin firmness and resilience while maintaining moisture without feeling heavy. It may also help calm redness and protect against environmental stress, leaving skin looking smooth and balanced.
Sources: [Nutrients, 2022](https://pubmed.ncbi.nlm.nih.gov/36501011/), [Molecules, 2024](https://pubmed.ncbi.nlm.nih.gov/38611748/)

### What does Hyaluronic Acid do for oily skin?

Hyaluronic acid helps oily skin by reducing extra oil and sebum production without causing irritation. Clinical studies show it successfully balances oil levels while keeping the skin comfortable.
Sources: [The Journal of Investigative Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28163068/)

### Where does this serum go in a skincare routine for oily skin?

This treatment serum goes in your evening routine after cleansing and before moisturizing, and it can also be used weekly. While it offers moderate plumping and safe hydration for oily skin, this skin type needs specialized ingredients to directly reduce oily shine.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first and following it with your retinol. This approach helps keep your skin soft and comfortable while you use active treatments.

### How often should I use this serum?

You can use this treatment in the evening as part of your routine. It is safe for your oily skin and unlikely to cause irritation.

### Can this serum clog pores, cause breakouts or purging for oily skin?

This serum is unlikely to clog pores or cause breakouts on oily skin, as it has a safe profile with gentle soothing components like glycerin. However, because it lacks specialized oil-controlling ingredients, an oily skin type needs lightweight formulas with mattifying or sebum-regulating actives to properly manage shine.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is this serum fragrance-free and alcohol-free?

It contains fragrance (linalool, limonene, geraniol, citronellol, citral, and benzyl alcohol) and drying alcohol (alcohol denat).

## Alternatives for oily skin

- [Clinique Fresh Pressed Daily Booster with Pure Vitamin C 10%](https://lovi.care/skincare/ae/p/clinique/fresh-pressed-daily-booster-with-pure-vitamin-c-10/for/oily-skin) — Superior fit — AED 365.22 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/ae/p/skinceuticals/c-e-ferulic/for/oily-skin) — High fit — AED 715.99 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/ae/p/neogen-dermalogy/real-vita-c-serum/for/oily-skin) — High fit — AED 89.30 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/ae/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — AED 49.95 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/ae/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — AED 49.99 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/ae/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/oily-skin) — Superior fit — AED 33.40 at Amazon

## Where to buy

- Amazon.ae: AED 35.99 (https://www.amazon.ae/dp/B085VWWJJT?tag=lovi00-21&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, Glycerin, Butylene Glycol, Cetyl Ethylhexanoate, Niacinamide, Glycereth-26, Alcohol Denat, 2-Hexanediol, Cyclopentasiloxane, Cyclohexasiloxane, Trehalose, Dimethicone, Carbomer, Cetearyl Olivate, Tromethamine, Sorbitan Olivate, Ethylhexylglycerin, Collagen Extract, Adenosine, Disodium Edta, Benzyl Benzoate, Linalool, Limonene, Geraniol, Atelocollagen, Desamido Collagen, Citronellol, Hydrolyzed Collagen, Sodium Hyaluronate, Water-Soluble Collagen, Hydroxycitronellal, Sodium Hyaluronate Crosspolymer, Hydrolyzed Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Collagen, Collagen Amino Acids, Sodium Acetylated Hyaluronate, Procollagen, Hydroxypropyltrimonium Hyaluronate, Citral, Benzyl Alcohol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medicube/triple-collagen-serum-4-0/for/oily-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medicube/triple-collagen-serum-4-0/for/oily-skin
- Ireland: https://lovi.care/skincare/ie/p/medicube/triple-collagen-serum-4-0/for/oily-skin
- Germany: https://lovi.care/skincare/de/p/medicube/triple-collagen-serum-4-0/for/oily-skin
- France: https://lovi.care/skincare/fr/p/medicube/triple-collagen-serum-4-0/for/oily-skin
- Italy: https://lovi.care/skincare/it/p/medicube/triple-collagen-serum-4-0/for/oily-skin
- Netherlands: https://lovi.care/skincare/nl/p/medicube/triple-collagen-serum-4-0/for/oily-skin
- Spain: https://lovi.care/skincare/es/p/medicube/triple-collagen-serum-4-0/for/oily-skin
- Canada: https://lovi.care/skincare/ca/p/medicube/triple-collagen-serum-4-0/for/oily-skin
- Australia: https://lovi.care/skincare/au/p/medicube/triple-collagen-serum-4-0/for/oily-skin
- Singapore: https://lovi.care/skincare/sg/p/medicube/triple-collagen-serum-4-0/for/oily-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/medicube/triple-collagen-serum-4-0/for/oily-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/medicube/triple-collagen-serum-4-0/for/oily-skin (this page)