# Medicube Deep Peptide Radiance Mask for mature skin

**Lovi Fit: High fit for mature skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/ae/p/medicube/deep-peptide-radiance-mask/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Arab Emirates.

Brand: [Medicube](https://lovi.care/skincare/ae/brands/medicube)
Category: [Face masks](https://lovi.care/skincare/ae/best/face-masks)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for mature skin; a few nourishing masks fit it even better.

## Why this fit

- This mask is highly suitable for your normal skin, as niacinamide and panthenol provide essential hydration and barrier support, while peptides like Acetyl Hexapeptide-1 and Palmitoyl Tripeptide-5 effectively target wrinkles and fine lines by promoting collagen synthesis and improving elasticity.
- The inclusion of Centella Asiatica Leaf Extract and other fermented lysates further enhances the soothing and skin-renewing benefits, making it a well-rounded treatment for your concerns.
- The product has a very safe profile, with no reported risks of irritation due to its gentle formulation and absence of harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ae/p/medicube/deep-peptide-radiance-mask/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/ae/p/medicube/deep-peptide-radiance-mask/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/ae/p/medicube/deep-peptide-radiance-mask/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/ae/p/medicube/deep-peptide-radiance-mask/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/ae/p/medicube/deep-peptide-radiance-mask/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/ae/p/medicube/deep-peptide-radiance-mask/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ae/p/medicube/deep-peptide-radiance-mask/for/mature-skin): High (this page)
- [Dry sensitive skin](https://lovi.care/skincare/ae/p/medicube/deep-peptide-radiance-mask/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/ae/p/medicube/deep-peptide-radiance-mask/for/oily-acne-prone-skin): Superior

## Key ingredients

Peptide Complex, Niacinamide, Centella Asiatica Leaf Extract, Hydrolyzed Hyaluronic Acid, Ceramide Np

## What the research says

- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))

## What reviewers say

Based on limited data, users love this mask for its intense hydration and ability to provide an instant glow, making it ideal for dry, dull, or sensitive skin. The peptide-rich essence is praised for plumping fine lines and soothing irritation without a sticky feel. Some users find the price high for frequent use and note the sheet size can be slightly small.

- Liked: Intense hydration (mostly mentioned)
- Liked: Instant radiance (often mentioned)
- Liked: Non-sticky finish (sometimes noted)
- Liked: Soothing and plumping (sometimes noted)
- Disliked: High price point (sometimes noted)
- Disliked: Handling difficulty (rarely noted)
- Disliked: Sheet fit issues (rarely noted)

## How to apply

- You can use this sheet mask in your PM routine about 2-3 times a week. Smooth it gently over your face and relax.
- Apply the sheet mask right after cleansing and toning, but before putting on your moisturizer.
- Place the sheet mask flat on your face and smooth it out gently with your fingers. Leave it on for ten to fifteen minutes before removing.
- Put the sheet mask on clean and dry skin for the best comfort. Gently pat any remaining essence into your skin after taking it off.
- Avoid getting the product into your eyes and do a quick patch test before your very first use.
- Video: https://storage.pora.ai/cf9cbc1593b43309df7ca9cfe4fbbdae.mp4

## Questions and answers

### What makes medicube Deep Peptide Radiance Mask a great fit for mature skin?

This mask is a great fit for mature skin because its peptides and niacinamide help smooth fine lines and support elasticity while keeping the skin hydrated. It also includes soothing centella extract and a gentle formula that is unlikely to cause irritation.
Sources: [Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/)

### Which ingredients make this mask a good fit for mature skin?

This mask is a great fit for mature skin because its peptide complex and niacinamide help smooth out wrinkles and fine lines while supporting firmness. Additionally, ingredients like centella asiatica leaf extract and ceramides keep the skin calm and hydrated with a very safe profile that is unlikely to cause irritation.
Sources: [Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/)

### What does Peptide Complex do for mature skin?

Peptide Complex helps smooth mature skin by supporting collagen production, which reduces the look of fine lines and wrinkles. Using it regularly may also improve overall firmness, elasticity, and hydration.
Sources: [International Journal of Cosmetic Science, 2005](https://pubmed.ncbi.nlm.nih.gov/18492182/), [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37335808/)

### What does Niacinamide do for mature skin?

Niacinamide helps mature skin by smoothing out fine lines and wrinkles, reducing dark spots, and improving overall skin elasticity. It is also very well tolerated and supports a strong skin barrier to keep skin looking healthy.
Sources: [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/), [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/)

### Where does this mask go in a skincare routine for mature skin?

This mask goes into your weekly routine after cleansing and an enzyme powder, followed by your treatment and moisturizer. It is unlikely to cause irritation due to its gentle formula, making it a safe weekly step for your skin.
Sources: [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Can I use this mask with retinol, and in what order?

You can use this mask in your weekly routine alongside retinol treatments, applying the mask first to nourish and soothe the skin before following up with your treatment and moisturizer. This gentle approach helps maintain skin comfort and supports your barrier.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this mask?

You can use this nourishing mask once a week as part of your weekly routine. Its gentle formulation has a very safe profile, so it is unlikely to cause irritation.
Sources: [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Can this mask clog pores, cause breakouts or purging for mature skin?

This mask is unlikely to clog pores or cause breakouts for mature skin, as it has a very safe profile and a gentle formula without harsh ingredients. It helps keep skin calm and smooth while providing deep hydration.

### Is this mask fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Behenyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for mature skin

- [Mediheal Watermide Essential Mask](https://lovi.care/skincare/ae/p/mediheal/watermide-essential-mask/for/mature-skin) — Superior fit — AED 65.00 at Amazon
- [Numbuzin No.2 Water Collagen 65% Voluming Sheet Mask](https://lovi.care/skincare/ae/p/numbuzin/no-2-water-collagen-65-voluming-sheet-mask/for/mature-skin) — High fit — AED 30.00 at Amazon
- [Dr. Jart+ Ceramidin Facial Barrier Mask](https://lovi.care/skincare/ae/p/dr-jart/ceramidin-facial-barrier-mask/for/mature-skin) — High fit — AED 181.38 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ae/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — AED 84.53 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/ae/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — AED 65.43 at Amazon
- Moisturizer: [Elizabeth Arden Ceramide Lift and Firm Night Cream](https://lovi.care/skincare/ae/p/elizabeth-arden/advanced-ceramide-lift-and-firm-night-cream/for/mature-skin) — Superior fit — AED 493.00 at Amazon

## Where to buy

- Amazon.ae: AED 49.99 (https://www.amazon.ae/dp/B0DT6X9R7J?tag=lovi00-21&linkCode=osi&th=1&psc=1)
Prices checked 2 Nov 2026.

## Ingredients

Water, Dipropylene Glycol, Glycerin, Butylene Glycol, Niacinamide, 1,2-Hexanediol, Cetyl Ethylhexanoate, Panthenol, Allantoin, Xylitol, Centella Asiatica Leaf Extract, Lactobacillus Lysate Ferment, Lactococcus Lysate Ferment, Bifida Lysate Ferment, Caprylyl Glycol, Sorbitan Laurate, Hydrogenated Lecithin, Hydrolyzed Hyaluronic Acid, Tocopherol, Asiaticoside, Madecassic Acid, Asiatic Acid, Acetyl Dipeptide-1, Cetyl Ester, Acetyl Hexapeptide-1, Palmitoyl Tripeptide-5, Beta-Glucan, Ceramide Np, Acetyl Octapeptide-3, Hydrogenated Oil, Behenyl Alcohol, Polyglyceryl-3 Methylglucose Distearate, Arginine, Carbomer, Adenosine, Hydroxyethylcellulose, Ethylhexylglycerin, Disodium Edta
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medicube/deep-peptide-radiance-mask/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medicube/deep-peptide-radiance-mask/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/medicube/deep-peptide-radiance-mask/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/medicube/deep-peptide-radiance-mask/for/mature-skin
- France: https://lovi.care/skincare/fr/p/medicube/deep-peptide-radiance-mask/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/medicube/deep-peptide-radiance-mask/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/medicube/deep-peptide-radiance-mask/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/medicube/deep-peptide-radiance-mask/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/medicube/deep-peptide-radiance-mask/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/medicube/deep-peptide-radiance-mask/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/medicube/deep-peptide-radiance-mask/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/medicube/deep-peptide-radiance-mask/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/medicube/deep-peptide-radiance-mask/for/mature-skin (this page)