# MEDI THERAPY Retinal Skin Booster for combination skin

**Lovi Fit: Average fit for combination skin.**
Combination Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/ae/p/medi-therapy/retinal-skin-booster/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Arab Emirates.

Brand: [MEDI THERAPY](https://lovi.care/skincare/ae/brands/medi-therapy)
Category: [Serums and treatments](https://lovi.care/skincare/ae/best/serums)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for combination skin; other serums fit it better.

## Why this fit

- Offers moderate treatment for minimizing fine lines and wrinkles due to the presence of retinal for smoothing texture, and is suitable for your combination skin as niacinamide helps with seboregulation.
- Centella Asiatica provides soothing benefits and general skincare for your oily shine and combination skin, though its pore-refining effects are mostly supportive.
- The product is safe for your combination skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ae/p/medi-therapy/retinal-skin-booster/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ae/p/medi-therapy/retinal-skin-booster/for/dry-skin): Caution
- [Combination skin](https://lovi.care/skincare/ae/p/medi-therapy/retinal-skin-booster/for/combination-skin): Average (this page)
- [Sensitive skin](https://lovi.care/skincare/ae/p/medi-therapy/retinal-skin-booster/for/sensitive-skin): Low
- [Acne-prone skin](https://lovi.care/skincare/ae/p/medi-therapy/retinal-skin-booster/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/ae/p/medi-therapy/retinal-skin-booster/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/ae/p/medi-therapy/retinal-skin-booster/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/ae/p/medi-therapy/retinal-skin-booster/for/dry-sensitive-skin): Caution
- [Oily acne-prone skin](https://lovi.care/skincare/ae/p/medi-therapy/retinal-skin-booster/for/oily-acne-prone-skin): Average

## Key ingredients

Retinal, Centella Asiatica, Niacinamide

## What the research says

- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Treatment with a combination of niacinamide and hyaluronic acid improved skin aging signs and demonstrated a senomorphic effect by decreasing SASP and autocrine signaling genes in women. ([Scientific Reports, 2024](https://pubmed.ncbi.nlm.nih.gov/39009698/))
- Topical treatment of nicotinamide, alone or in combination with other active ingredients, reduces the progression of skin aging and hyperpigmentation in clinical trials while being well tolerated. ([Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- Twice daily application of retinaldehyde 0.1% and 0.05% creams for 3 months improved skin texture and hydration and reduced transepidermal water loss in 40 female Korean volunteers, with only the 0.1% cream significantly improving the melanin index. ([Journal of Cosmetic Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29663701/))
- Topical retinaldehyde demonstrated significant antibacterial activity against gram-positive bacteria both in vitro and in vivo, leading to decreased bacterial counts without inducing resistance. ([Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12218231/))
- Topical 0.05% retinaldehyde applied over 1 year significantly increased epidermal thickness of the temple and cutaneous elasticity compared to an emollient control group in 40 aging skin patients. ([Dermatology, 1999](https://pubmed.ncbi.nlm.nih.gov/10473959/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical 2% niacinamide significantly decreased sebum excretion rate in Japanese individuals and casual sebum levels in Caucasian individuals compared to placebo or baseline. ([Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/))

## What reviewers say

Based on a very large amount of data, users with sensitive, acne-prone, and aging skin report this product is gentle and effective, improving skin texture and hydration without irritation. Many users notice a radiant glow, reduced pore visibility, and smoother skin. Some users with very dry skin mention needing additional moisturization.

- Liked: Gentle & non-irritating (mostly mentioned)
- Liked: Hydrating & lightweight (often mentioned)
- Liked: Improves texture & pores (often mentioned)
- Liked: Fades acne & marks (sometimes noted)
- Liked: Great value (sometimes noted)
- Disliked: Dry skin needs more (rarely noted)
- Disliked: Mild stinging (rarely noted)
- Disliked: No visible change (rarely noted)
- Disliked: Packaging quality (rarely noted)
- Disliked: Sticky finish (rarely noted)

## How to apply

- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does MEDI THERAPY Retinal Skin Booster work for combination skin?

MEDI THERAPY Retinal Skin Booster works reasonably well for combination skin by smoothing texture, calming oily shine, and helping with fine lines, though other products fit this skin type better. To achieve the best results for combination skin, a product needs effective ingredients like niacinamide, propolis, or zinc PCA that regulate oiliness, enhance radiance, and provide balanced hydration without causing excess oiliness or dryness.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/)

### Which ingredients make this booster a good fit for combination skin?

Retinal, niacinamide, and Centella Asiatica make this booster a fit by smoothing texture, balancing oil, and calming the skin. Niacinamide helps manage shine, while Centella Asiatica provides soothing benefits. To work best for combination skin, a product of this type needs effective ingredients like niacinamide, propolis, and zinc PCA to provide balanced hydration and regulate oil without irritation.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/)

### What does Retinal do for combination skin?

Retinal helps smooth the skin and reduces signs of aging or breakouts when used regularly. It is unlikely to cause severe irritation when introduced gradually, keeping combination skin feeling calm and smooth.
Sources: [European Review for Medical and Pharmacological Sciences, 2014](https://pubmed.ncbi.nlm.nih.gov/25219827/), [Journal of Cosmetic Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/21649816/)

### What does Centella Asiatica do for combination skin?

Centella asiatica helps calm combination skin, keeps it balanced, and supports the moisture barrier without feeling heavy. It may also reduce redness and help keep breakouts under control.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### Where does this booster go in a skincare routine for combination skin?

This treatment goes in the evening routine after your cleansing toner and before your moisturizer. Treatments with active ingredients are placed at night for simplicity and extra safety around sun exposure.

### Can I use this booster with vitamin C, and in what order?

This retinal booster is used in your evening routine after cleansing and toning, and before moisturizing. Because it contains active ingredients, combining it directly with vitamin C in the same routine may increase the likelihood of skin irritation, so it is safer to use vitamin C in the morning and this treatment at night.

### How often should I use this booster?

Use this booster in your evening routine, starting just once a week to see how your skin reacts. If your skin feels comfortable and tolerates it well, you may carefully use it more often.
Sources: [Facial Plastic Surgery, 2014](https://pubmed.ncbi.nlm.nih.gov/24488631/)

### Can this booster clog pores, cause breakouts or purging for combination skin?

This booster is unlikely to clog pores or cause breakouts on combination skin because it avoids harsh ingredients and includes niacinamide to help balance oil. However, a product for combination skin ideally needs lightweight hydrating ingredients like hyaluronic acid and proven pore-clearing agents like salicylic acid to keep pores clear.
Sources: [Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/), [Scientific Reports, 2024](https://pubmed.ncbi.nlm.nih.gov/39009698/)

## Alternatives for combination skin

- [Augustinus Bader The Serum](https://lovi.care/skincare/ae/p/augustinus-bader/the-serum/for/combination-skin) — Superior fit — AED 1,348.00 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/ae/p/skinceuticals/c-e-ferulic/for/combination-skin) — Superior fit — AED 715.99 at Amazon
- [Clinique Fresh Pressed Daily Booster with Pure Vitamin C 10%](https://lovi.care/skincare/ae/p/clinique/fresh-pressed-daily-booster-with-pure-vitamin-c-10/for/combination-skin) — Superior fit — AED 365.22 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ae/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — AED 84.53 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/ae/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — AED 145.00 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/ae/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — AED 33.40 at Amazon

## Where to buy

No store in United Arab Emirates has a checked price for this product, so the page shows none.

## Ingredients

Retinal, Centella Asiatica, Niacinamide
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medi-therapy/retinal-skin-booster/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medi-therapy/retinal-skin-booster/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/medi-therapy/retinal-skin-booster/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/medi-therapy/retinal-skin-booster/for/combination-skin
- France: https://lovi.care/skincare/fr/p/medi-therapy/retinal-skin-booster/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/medi-therapy/retinal-skin-booster/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/medi-therapy/retinal-skin-booster/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/medi-therapy/retinal-skin-booster/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/medi-therapy/retinal-skin-booster/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/medi-therapy/retinal-skin-booster/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/medi-therapy/retinal-skin-booster/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/medi-therapy/retinal-skin-booster/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/medi-therapy/retinal-skin-booster/for/combination-skin (this page)