# Medi-Peel Cica Antio Cream for dry skin

**Lovi Fit: Average fit for dry skin.**
Dry Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/ae/p/medi-peel/cica-antio-cream/for/dry-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Arab Emirates.

Brand: [Medi-Peel](https://lovi.care/skincare/ae/brands/medi-peel)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/ae/best/moisturizers)

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for dry skin; other moisturizers fit it better.

## Why this fit

- Offers moderate benefits for your dry skin, as glycerin and sodium hyaluronate crosspolymer provide essential hydration and occlusive action to combat dryness and flakiness. Shea butter further supports emollient needs, though its richness may be more than necessary for some dry skin types.
- Niacinamide and Centella Asiatica Extract offer additional soothing and tone-improving benefits, contributing to overall skin health.
- The product is safe for your dry skin, containing no harsh ingredients and featuring soothing components like Centella Asiatica Extract and Licorice Root Extract.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ae/p/medi-peel/cica-antio-cream/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ae/p/medi-peel/cica-antio-cream/for/dry-skin): Average (this page)
- [Combination skin](https://lovi.care/skincare/ae/p/medi-peel/cica-antio-cream/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/ae/p/medi-peel/cica-antio-cream/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/ae/p/medi-peel/cica-antio-cream/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/ae/p/medi-peel/cica-antio-cream/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/ae/p/medi-peel/cica-antio-cream/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/ae/p/medi-peel/cica-antio-cream/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/ae/p/medi-peel/cica-antio-cream/for/oily-acne-prone-skin): Average

## Key ingredients

Centella Asiatica Extract, Niacinamide, Sodium Hyaluronate, Squalane, Ceramide Np

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))

## What reviewers say

This cream is widely praised as a rescue treatment for damaged skin barriers, effectively calming redness and inflammation associated with acne and sensitivity. While many users with dry or combination skin love its deep hydration and healing properties, those with very oily skin sometimes find the texture too heavy or occlusive, occasionally leading to clogged pores.

- Liked: Soothes redness (mostly mentioned)
- Liked: Deep hydration (often mentioned)
- Disliked: Poor packaging (often mentioned)
- Liked: Improves acne (sometimes noted)
- Liked: Pleasant texture (sometimes noted)
- Disliked: Sticky/heavy finish (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Ineffective for some (rarely noted)

## How to apply

- Could be used as part of your AM or PM routine. Start using it 3 times a week and work your way up to daily use.
- Apply your moisturizer after your toner and before your sunscreen in the morning. At night, use it as the final step after your serum.
- Gently press a small amount of the moisturizer into your skin. Avoid rubbing to keep your dry skin happy.
- Apply the moisturizer on slightly damp skin to help lock in extra hydration. This is great for soothing dry and flaky areas .
- Avoid the sensitive eye area and do a patch test before your first use .
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Medi-Peel Cica Antio Cream work for dry skin?

Medi-Peel Cica Antio Cream works moderately well for dry skin, providing essential hydration and soothing benefits through ingredients like glycerin and Centella Asiatica Extract. Dry skin of this type needs rich, nourishing ingredients that deeply lock in moisture, support the skin barrier, and provide intense hydration without any risk of irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this cream a good fit for dry skin?

Glycerin, sodium hyaluronate crosspolymer, and shea butter make this cream a good fit by providing essential hydration, moisture-locking benefits, and softness to combat dryness and flakiness. Niacinamide and centella asiatica extract also help soothe and improve overall skin health. To fit dry skin even better, this type of product needs highly effective soothing ingredients, deep nourishment, and strong skin barrier support without any risk of irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Centella Asiatica Extract do for dry skin?

Centella asiatica extract helps dry skin by boosting moisture and reducing water loss while calming irritation. It supports barrier repair to keep the skin feeling soft and smooth.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Niacinamide do for dry skin?

Niacinamide helps dry skin by strengthening the skin barrier, increasing hydration, and reducing water loss. It supports ceramide production and helps keep the surface smooth and calm. This ingredient tends to be very well tolerated and is unlikely to irritate dry skin.
Sources: [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/), [Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/42108609/)

### Where does it go in a skincare routine for dry skin?

This treatment goes in the evening routine after cleansing. Dry skin works best with products that provide deep hydration and rich sealing ingredients to lock in moisture and soothe flakiness.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this cream with retinol, and in what order?

You can use this cream with retinol by applying the retinol first, letting it absorb, and then following with this moisturizer. This routine helps keep your dry skin calm and comfortable while reducing the dryness and flakiness that retinol can sometimes cause.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use it?

This moisturizing treatment works well as part of your evening routine. Daily application helps improve skin moisture and keeps dry skin feeling soft and smooth.
Sources: [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/), [Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/14571069/)

### Can this cream clog pores, cause breakouts or purging for dry skin?

This cream is unlikely to cause breakouts for dry skin, as it contains no harsh ingredients and features soothing components like Centella Asiatica Extract and Licorice Root Extract. Reviewers rarely report breakouts from using it.

### Can I use it around the eyes or on my body?

You can use this moisturizing treatment around the eyes and on your body, as it features a safe formula with soothing ingredients like centella asiatica extract and licorice root extract. Because dry skin often needs richer hydration and barrier support in those areas, a product of this type works best when it combines heavy sealing butters with deep moisture-holding ingredients.

### Is this cream fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (hexyl cinnamal, limonene, linalool, and citronellol). Cetearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for dry skin

- [SKIN1004 Madagascar Centella Probio-Cica Enrich Cream](https://lovi.care/skincare/ae/p/skin1004/madagascar-centella-probio-cica-enrich-cream/for/dry-skin) — Superior fit — AED 34.80 at Amazon
- [Obagi Hydrate Luxe Moisture-Rich Cream](https://lovi.care/skincare/ae/p/obagi/hydrate-luxe/for/dry-skin) — Superior fit — AED 244.74 at Amazon
- [The Ordinary Natural Moisturizing Factors + HA](https://lovi.care/skincare/ae/p/the-ordinary/natural-moisturizing-factors-ha/for/dry-skin) — Superior fit — AED 65.00 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/ae/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — AED 32.95 at Amazon
- SPF: [Dr.G Green Mild Up Sun+](https://lovi.care/skincare/ae/p/dr-g/green-mild-up-sun/for/dry-skin) — Superior fit — AED 81.00 at Amazon
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/ae/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — AED 35.29 at Amazon

## Where to buy

No store in United Arab Emirates has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Caprylic Capric Triglyceride, Cetearyl Alcohol, Dipropylene Glycol, Niacinamide, Glyceryl Stearate, Peg-100 Stearate, Betaine, Sorbitan Stearate, Arginine, Carbomer, Hydroxyacetophenone, Dimethicone, Caprylyl Glycol, Melia Azadirachta Leaf Extract, Dipotassium Glycyrrhizate, Wheat Extract Sprout, Centella Asiatica Extract, Melia Azadirachta Flower Extract, Coccinia Indica Fruit Extract, Ethylhexylglycerin, Curcuma Longa Root Extract, Eclipta Prostrata Extract, Adenosine, Corallina Officinalis Extract, Ocimum Sanctum Leaf Extract, Glyceryl Acrylate Acrylic Acid Copolymer, Solanum Melongena Fruit Extract, Disodium Edta, Allantoin, Aloe Barbadensis Flower Extract, Tocopheryl Acetate, Panthenol, Propylene Glycol, Propanediol, Beta-Glucan, Squalane, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Fructan, Butylene Glycol, Sodium Hyaluronate Crosspolymer, Glyceryl Polymethacrylate, Sodium Hyaluronate, Hydrolyzed Glycosaminoglycans, Butyrospermum Parkii Butter Shea Butter, 1,2-Hexanediol, Olea Europaea Leaf Extract Olive Leaf Extract, Mannan, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Dandelion Leaf Extract, Benzyl Glycol, Ceramide Np, Phytosphingosine, Hydrolyzed Hyaluronic Acid, Rosa Damascena Flower Extract, Rhodiola Rosea Root Extract, Origanum Vulgare Leaf Extract, Palmitoyl Tripeptide-5, Chamaecyparis Obtusa Leaf Extract, Willow Bark Extract, Usnea Barbata Extract, Zanthoxylum Piperitum Fruit Extract, Pulsatilla Koreana Extract, Lactobacillus Soybean Extract Ferment, Portulaca Oleracea Extract, Citric Acid, Cinnamomum Cassia Bark Extract, Scutellaria Baicalensis Root Extract, Raspberry Ketone, Acetyl Hexapeptide-8, Copper Tripeptide-1, Oligopeptide-29, Oligopeptide-32, Palmitoyl Oligopeptide, Palmitoyl Pentapeptide-4, Hexyl Cinnamal, Limonene, Linalool, Citronellol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medi-peel/cica-antio-cream/for/dry-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medi-peel/cica-antio-cream/for/dry-skin
- Ireland: https://lovi.care/skincare/ie/p/medi-peel/cica-antio-cream/for/dry-skin
- Germany: https://lovi.care/skincare/de/p/medi-peel/cica-antio-cream/for/dry-skin
- France: https://lovi.care/skincare/fr/p/medi-peel/cica-antio-cream/for/dry-skin
- Italy: https://lovi.care/skincare/it/p/medi-peel/cica-antio-cream/for/dry-skin
- Netherlands: https://lovi.care/skincare/nl/p/medi-peel/cica-antio-cream/for/dry-skin
- Spain: https://lovi.care/skincare/es/p/medi-peel/cica-antio-cream/for/dry-skin
- Canada: https://lovi.care/skincare/ca/p/medi-peel/cica-antio-cream/for/dry-skin
- Australia: https://lovi.care/skincare/au/p/medi-peel/cica-antio-cream/for/dry-skin
- Singapore: https://lovi.care/skincare/sg/p/medi-peel/cica-antio-cream/for/dry-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/medi-peel/cica-antio-cream/for/dry-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/medi-peel/cica-antio-cream/for/dry-skin (this page)