# Mederma PM Intensive Overnight Scar Cream for combination skin

**Lovi Fit: Low fit for combination skin.**
Combination Skin Fit: Average · Effectiveness: High · Safety: Concerning.

Page: https://lovi.care/skincare/ae/p/mederma/pm-intensive-overnight-scar-cream/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Arab Emirates.

Brand: [Mederma](https://lovi.care/skincare/ae/brands/mederma)
Category: [Serums and treatments](https://lovi.care/skincare/ae/best/serums)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A weak match for combination skin; the serums alongside fit it better.

## Why this fit

- Offers moderate scar treatment for your combination skin, as onion bulb extract and copper tripeptide-1 work to improve scar appearance, while glycerin provides hydration. However, the formula lacks specialized ingredients for effective oil control, which is your main concern for oily shine.
- The presence of alcohol in the formulation may pose a slight risk of irritation for your skin.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ae/p/mederma/pm-intensive-overnight-scar-cream/for/oily-skin): Low
- [Dry skin](https://lovi.care/skincare/ae/p/mederma/pm-intensive-overnight-scar-cream/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/ae/p/mederma/pm-intensive-overnight-scar-cream/for/combination-skin): Low (this page)
- [Sensitive skin](https://lovi.care/skincare/ae/p/mederma/pm-intensive-overnight-scar-cream/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/ae/p/mederma/pm-intensive-overnight-scar-cream/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/ae/p/mederma/pm-intensive-overnight-scar-cream/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/ae/p/mederma/pm-intensive-overnight-scar-cream/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/ae/p/mederma/pm-intensive-overnight-scar-cream/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/ae/p/mederma/pm-intensive-overnight-scar-cream/for/oily-acne-prone-skin): Average

## Key ingredients

Dimethicone, Onion Bulb Extract, Copper Tripeptide-1, Aloe Barbadensis Leaf, Hydrolyzed Collagen

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate can be used safely in cosmetic formulations at concentrations up to 5%, and Benzyl Alcohol is safe up to 10% in hair dyes, despite causing nonimmunologic contact reactions. ([International Journal of Toxicology, 2001](https://pubmed.ncbi.nlm.nih.gov/11766131/))
- Wearing an N95 mask alone compared to using dimethicone cream or hydrocolloid dressing caused more adverse skin reactions among 73 military health care workers, with no significant differences in fit test failure rates between groups. ([Military Medicine, 2024](https://pubmed.ncbi.nlm.nih.gov/38771104/))
- A dimethicone skin protectant lotion significantly decreased visual scoring and transepidermal water loss compared to vehicle control and SLS-only treated sites in 12 healthy humans exposed to sodium lauryl sulfate. ([Skin Research and Technology, 2000](https://pubmed.ncbi.nlm.nih.gov/11428946/))
- Treatment with a moisturizer containing dimethicone and glycerine increased epidermal thickness by 0.019 mm, improved barrier function by decreasing transepidermal water loss by 13%, decreased melanin intensity, and induced keratins 6 and 16 in fifteen women with moderately photoaged forearms. ([Clinical and Experimental Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17137484/))
- Topical onion extract improved scar colour compared to silicon gel, while silicon gel was superior in decreasing scar height in 60 patients with hypertrophic and keloid scars, with the most effective results obtained from combining onion extract and silicon gel. ([Journal of Wound Care, 2007](https://pubmed.ncbi.nlm.nih.gov/17722521/))
- Silicone derivative plus onion extract gel reduced pain, itching, and pigmentation compared to placebo in patients after median sternotomy. ([International Wound Journal, 2012](https://pubmed.ncbi.nlm.nih.gov/22168750/))
- Topical 12% onion extract gel applied early on Pfannenstiel's cesarean section scars in Asians improved scar height and scar symptoms compared to placebo, with no significant difference in scar redness, pliability, or overall appearance. ([Dermatology Research and Practice, 2012](https://pubmed.ncbi.nlm.nih.gov/22924037/))
- Topical copper tripeptide complex on CO2 laser-resurfaced skin caused no significant reduction in erythema or objective improvement in wrinkles compared to controls, but significantly increased patient satisfaction regarding overall skin quality. ([Archives of Facial Plastic Surgery, 2006](https://pubmed.ncbi.nlm.nih.gov/16847171/))
- A novel regimen combining a hydroxy acid-based scrub and copper tripeptide serum significantly reduced adherent scalp flaking by 61.24%, increased hair density by 12.48%, increased hair thickness by 25.36%, and improved scalp skin hydration by 76.24% in adults with mild to moderate dandruff over 15 days. ([Cureus, 2024](https://pubmed.ncbi.nlm.nih.gov/39449909/))
- The combination of Thermus thermophilus and Bacillus subtilis mixed-culture ferment extract and copper tripeptide-1 GHK-Cu reduced inflammatory cytokines, protected skin explants from UV-induced damage, and improved wrinkles and skin barrier conditions compared to individual components or controls. ([Skin Research and Technology, 2026](https://pubmed.ncbi.nlm.nih.gov/42573538/))
- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Topical aloe vera gel significantly accelerated split-thickness skin graft donor-site healing compared to placebo in 12 patients, but showed no significant difference in pain relief. ([Plastic and Reconstructive Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29649056/))
- Topical application of Aloe vera cream reduced postoperative pain at rest and during defecation, accelerated wound healing at two weeks, and decreased analgesic requirements in patients after open hemorrhoidectomy compared to placebo. ([Journal of Alternative and Complementary Medicine, 2010](https://pubmed.ncbi.nlm.nih.gov/20569031/))
- Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35818134/))
- Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks. ([International Journal of Molecular Sciences, 2022](https://pubmed.ncbi.nlm.nih.gov/35163025/))
- Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers. ([Marine Drugs, 2023](https://pubmed.ncbi.nlm.nih.gov/36827098/))

## Why other serums fit combination skin better

- Topical benzoyl peroxide 5% gel treatment improved acne severity, sebum, stratum corneum hydration, and transepidermal water loss, while significantly reducing microbial diversity and the prevalence of Cutibacterium in 33 patients with acne vulgaris. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/34962033/))
- Application of Galactomyces ferment filtrate skin care formula significantly reduced the net values and daily fluctuation of facial pore area, roughness, and redness in young Japanese women. ([Journal of Clinical Medicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34198790/))

## What reviewers say

Based on a very large amount of data, users report this cream is effective at softening and flattening scars from surgery, acne, and injuries with consistent use over months. Many appreciate the convenient, non-greasy application. However, results can take a long time to become noticeable, and a significant number of users find the scent unpleasant.

- Liked: Effective on scars (often mentioned)
- Disliked: Slow results (often mentioned)
- Disliked: Unpleasant smell (often mentioned)
- Liked: Convenient application (sometimes noted)
- Liked: Good absorption (sometimes noted)
- Liked: Improves texture (sometimes noted)
- Disliked: Price vs quantity (sometimes noted)
- Disliked: Skin reactions (rarely noted)

## How to apply

- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### Why is Mederma PM Intensive Overnight Scar Cream a weak match for combination skin?

This cream is a weak match for your combination skin because it lacks specialized ingredients to control oily shine, and the alcohol it contains may pose a slight risk of irritation. A treatment for this skin needs non-irritating ingredients that manage oily shine and balance hydration without causing adverse effects.

### Which ingredients make this cream a poor fit for combination skin?

This cream is a weak match for your combination skin because it lacks specialized ingredients for oil control and contains alcohol, which may pose a slight risk of irritation. A treatment of this type needs balancing ingredients that manage oily shine and provide hydration without causing irritation or unsuitability.

### What does Dimethicone do for combination skin?

Dimethicone helps protect combination skin by forming a light barrier that smooths the surface without feeling heavy or greasy. It may keep skin soft and comfortable, though it is unlikely to deeply moisturize dry areas or control excess oil on its own.
Sources: [Military Medicine, 2024](https://pubmed.ncbi.nlm.nih.gov/38771104/), [Skin Pharmacology and Physiology, 2014](https://pubmed.ncbi.nlm.nih.gov/24457536/)

### What does Onion Bulb Extract do for combination skin?

For combination skin, a product of this type needs soothing ingredients and antioxidants to help balance oily and dry areas while keeping the skin calm and smooth.
Sources: [Journal of Food Science, 2022](https://pubmed.ncbi.nlm.nih.gov/36101019/)

### Where does this cream go in a skincare routine for combination skin?

This treatment goes in the evening routine after cleansing and toning, and before moisturizing. Because it is a weak match for combination skin, this skin type needs oil-balancing ingredients to manage oily shine.

### Can I use this cream with retinol, and in what order?

You can use this cream in your evening routine, applying it after your retinol treatment. A product of this type needs specialized ingredients for oil control to help manage oily shine on combination skin.

### How often should I use this cream?

You can use this cream in the evening as part of your nighttime routine, applying it just before your moisturizer. Because this formula lacks oil-controlling ingredients and contains alcohol, it is a weak match for your combination skin and needs added oil-balancing ingredients and soothing hydrators.

### Can this cream clog pores, cause breakouts or purging for combination skin?

This cream is unlikely to clog pores or cause breakouts for your combination skin, but the alcohol in the formula may cause mild irritation. Because it lacks ingredients for oil control, combination skin needs a treatment that balances hydration with oil-controlling ingredients.
Sources: [International Journal of Toxicology, 2001](https://pubmed.ncbi.nlm.nih.gov/11766131/)

### Is this cream fragrance-free and alcohol-free?

It has no fragrance and contains drying alcohol (alcohol and isopropyl alcohol).

## Alternatives for combination skin

- [Dewytree Miracle Clear Serum](https://lovi.care/skincare/ae/p/dewytree/miracle-clear-serum/for/combination-skin) — High fit — AED 74.78 at Amazon
- [REN Clean Skincare Clearcalm Non-Drying Acne Treatment Gel](https://lovi.care/skincare/ae/p/ren-clean-skincare/clearcalm-non-drying-acne-treatment-gel/for/combination-skin) — High fit — AED 233.00 at Amazon
- [Clean & Clear Persa-Gel 10 Acne Medication](https://lovi.care/skincare/ae/p/clean-and-clear/persa-gel-10/for/combination-skin) — High fit — AED 36.96 at Amazon

## Routine for combination skin

### AM

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ae/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — AED 84.53 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/ae/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — AED 145.00 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/ae/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — AED 33.40 at Amazon

### PM

- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/ae/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/combination-skin) — Superior fit — AED 179.45 at Amazon
- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ae/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — AED 84.53 at Amazon
- Cleansing Toner: [Medicube Zero Pore Pad 2.0](https://lovi.care/skincare/ae/p/medicube/zero-pore-pad-2-0/for/combination-skin) — Superior fit — AED 53.12 at Amazon
- Serum or Treatment: [Peach & Lily Glass Skin Refining Serum](https://lovi.care/skincare/ae/p/peach-and-lily/glass-skin-refining-serum/for/combination-skin) — Superior fit — AED 168.76 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/ae/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — AED 33.40 at Amazon

### Weekly

- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/ae/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/combination-skin) — Superior fit — AED 179.45 at Amazon
- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ae/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — AED 84.53 at Amazon
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/ae/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — AED 101.09 at Amazon
- Cleansing Mask: [Kora Organics Turmeric Brightening & Exfoliating Mask](https://lovi.care/skincare/ae/p/kora-organics/turmeric-brightening-and-exfoliating-mask/for/combination-skin) — Superior fit — AED 122.93 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/ae/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — AED 145.00 at Amazon
- Serum or Treatment: [Peach & Lily Glass Skin Refining Serum](https://lovi.care/skincare/ae/p/peach-and-lily/glass-skin-refining-serum/for/combination-skin) — Superior fit — AED 168.76 at Amazon

## Where to buy

No store in United Arab Emirates has a checked price for this product, so the page shows none.

## Ingredients

Water, Cetearyl Alcohol, Glycerin, C12-15 Alkyl Benzoate, Dicaprylyl Carbonate, Pentylene Glycol, Cyclomethicone, Arachidyl Alcohol, Alcohol, Behenyl Alcohol, Arachidyl Glucoside, Onion Bulb Extract, Copper Tripeptide-1, Aloe Barbadensis Leaf, Cetearyl Glucoside, Tocopheryl Acetate, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Hydroxyethylcellulose, Hydrolyzed Soy Protein, Glycine, Panthenol, Hydrolyzed Collagen, Peg-400, Arginine Hcl, Leucine, Lysine Hydrochloride, Alanine, Sodium Lactate, Aspartic Acid, Glucose, Glutamic Acid, Isopropyl Alcohol, Mannitol, Sorbitol, Tromethamine, Valine, Histidine Hydrochloride, Isoleucine, Phenylalanine, Tyrosine, Potassium Sorbate, Sodium Benzoate, Citric Acid, Sodium Hydroxide
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/mederma/pm-intensive-overnight-scar-cream/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/mederma/pm-intensive-overnight-scar-cream/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/mederma/pm-intensive-overnight-scar-cream/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/mederma/pm-intensive-overnight-scar-cream/for/combination-skin
- France: https://lovi.care/skincare/fr/p/mederma/pm-intensive-overnight-scar-cream/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/mederma/pm-intensive-overnight-scar-cream/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/mederma/pm-intensive-overnight-scar-cream/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/mederma/pm-intensive-overnight-scar-cream/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/mederma/pm-intensive-overnight-scar-cream/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/mederma/pm-intensive-overnight-scar-cream/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/mederma/pm-intensive-overnight-scar-cream/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/mederma/pm-intensive-overnight-scar-cream/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/mederma/pm-intensive-overnight-scar-cream/for/combination-skin (this page)