# Le Mieux Bio Cell Rejuvenating Cream for oily acne-prone skin

**Lovi Fit: Average fit for oily acne-prone skin.**
Oily Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/ae/p/le-mieux/bio-cell-rejuvenating-cream/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Arab Emirates.

Brand: [Le Mieux](https://lovi.care/skincare/ae/brands/le-mieux)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/ae/best/moisturizers)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily acne-prone skin; other moisturizers fit it better.

## Why this fit

- Offers moderate suitability for your oily skin, as Squalane and Jojoba Seed Oil provide emollient action, but it lacks sufficient ingredients for strong oil control to address your acne, blemishes, and breakouts.
- The presence of Sodium Hyaluronate and Saccharomyces Lysate Extract offers general hydration and soothing benefits, which are supportive but not specifically targeted for your primary concerns.
- The safety profile is good, with no risks of irritation for your oily skin due to the absence of harsh ingredients and the inclusion of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ae/p/le-mieux/bio-cell-rejuvenating-cream/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ae/p/le-mieux/bio-cell-rejuvenating-cream/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/ae/p/le-mieux/bio-cell-rejuvenating-cream/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/ae/p/le-mieux/bio-cell-rejuvenating-cream/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/ae/p/le-mieux/bio-cell-rejuvenating-cream/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/ae/p/le-mieux/bio-cell-rejuvenating-cream/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/ae/p/le-mieux/bio-cell-rejuvenating-cream/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/ae/p/le-mieux/bio-cell-rejuvenating-cream/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/ae/p/le-mieux/bio-cell-rejuvenating-cream/for/oily-acne-prone-skin): Average (this page)

## Key ingredients

Sodium Hyaluronate, Squalane, Argan Oil, Acetyl Hexapeptide-8, Ceramide Np

## What the research says

- Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/))
- Hyaluronic acid extracts are safe and efficacious products for skin repair when used in tissue regeneration alone or in combination with herbal or Western medicine. ([Journal of Pharmacy & Pharmaceutical Sciences, 2015](https://pubmed.ncbi.nlm.nih.gov/25877441/))
- Optimized transfersomes loaded with epigallocatechin-3-gallate and hyaluronic acid increased cell viability while reducing lipid peroxidation, intracellular ROS, and MMP expression in HaCaT cells, and exhibited higher skin permeation and deposition compared to plain EGCG. ([Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/))
- Topical application of jojoba wax reduced LPS-induced secretion of IL-6, IL-8, and TNFα by approximately 30% and increased the synthesis of pro-collagen III and hyaluronic acid compared to untreated skin in an ex-vivo human skin organ culture model. ([Frontiers in Pharmacology, 2024](https://pubmed.ncbi.nlm.nih.gov/38344180/))
- Clay jojoba oil facial masks reduced total skin lesions by a mean of 54% after 6 weeks in 133 participants with acne-prone, lesioned skin and mild acne compared to baseline. ([Forschende Komplementarmedizin, 2012](https://pubmed.ncbi.nlm.nih.gov/22585103/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))
- A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events. ([Lasers in Medical Science, 2025](https://pubmed.ncbi.nlm.nih.gov/41134387/))
- Topical application of an argan oil NLC-based hydrogel formulation increased skin hydration in healthy volunteers over a one-month period through a synergistic effect of NLC occlusion and argan oil hydration. ([International Journal of Nanomedicine, 2014](https://pubmed.ncbi.nlm.nih.gov/25143733/))
- Incorporating allantoin into argan oil enriched liposomes improved its accumulation in the dermis (~8.7μg/cm(2)) and permeation through the skin (~33μg/cm(2)) compared to conventional liposomes, water dispersion, and a commercial gel. ([International Journal of Pharmaceutics, 2016](https://pubmed.ncbi.nlm.nih.gov/27063848/))
- Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days. ([Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/))
- Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group. ([American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/))
- Acetyl hexapeptide-3 and tripeptide-10 citrulline demonstrated antiwrinkle efficacy and decreased transepidermal water loss in twenty-four healthy volunteers compared to control groups, though synergistic effects between the two peptides remained unclear. ([Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28150423/))

## Why other moisturizers fit oily acne-prone skin better

- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- A peel-off facial mask containing myoinositol and trehalose-loaded liposomes improved adult female acne by decreasing lesion counts, sebum production, GAGS scores, and local androgen levels while increasing beclin-1 levels. ([Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28342238/))
- A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/))

## What reviewers say

This moisturizer is widely celebrated for its rich, non-greasy formula that effectively targets dehydration, loss of firmness, and fine lines. It is particularly favored by users with dry or mature skin types who seek a product that leaves the complexion feeling soft, supple, and visibly rejuvenated.

- Liked: Deep hydration (mostly mentioned)
- Liked: Radiant finish (often mentioned)
- Liked: Silky texture (often mentioned)
- Liked: Improves lines (sometimes noted)
- Disliked: Irritation risk (rarely noted)
- Disliked: Price point (rarely noted)
- Disliked: Too rich (rarely noted)

## How to apply

- Use this AM and PM routine every day to help clear your skin. Always remember to finish with SPF in the morning.
- Apply the moisturizer after your cleanser and toner, right before your SPF during the day.
- Gently press a small amount into your skin and avoid rubbing to keep pores clear.
- Apply on clean, slightly damp skin to help the product absorb better and control oil.
- Avoid the sensitive eye area and do a simple patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Le Mieux Bio Cell Rejuvenating Cream work for oily acne-prone skin?

Le Mieux Bio Cell Rejuvenating Cream works moderately well for oily acne-prone skin, as it provides basic moisture and soothing benefits, but it lacks strong ingredients to control oil and breakouts. Oily acne-prone skin needs lightweight hydration, ingredients that clear blemishes without clogging pores, and powerful oil-controlling components.
Sources: [Frontiers in Pharmacology, 2024](https://pubmed.ncbi.nlm.nih.gov/38344180/), [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Which ingredients make this cream a good fit for oily acne-prone skin?

Sodium Hyaluronate, Squalane, and jojoba seed oil make this cream a moderate fit by offering hydration and soothing benefits. However, oily acne-prone skin needs a product with strong oil control ingredients that target breakouts and blemishes without clogging pores.
Sources: [Frontiers in Pharmacology, 2024](https://pubmed.ncbi.nlm.nih.gov/38344180/), [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### What does Hyaluronic Acid do for oily acne-prone skin?

Hyaluronic acid helps calm oily acne-prone skin by reducing sebum production and lipid synthesis in sebaceous glands. It also supports skin barrier function and improves hydration while helping deliver treatments without causing irritation.
Sources: [The Journal of Investigative Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28163068/), [Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35796638/)

### What does Squalane do for oily acne-prone skin?

Squalane may help keep oily skin soft and smooth, but oxidized squalene can trigger inflammation in acne-prone skin. Because of this, oily acne-prone skin needs lightweight, non-greasy ingredients that balance moisture without clogging pores.
Sources: [The Journal of Investigative Dermatology, 2006](https://pubmed.ncbi.nlm.nih.gov/16778793/)

### Where does this cream go in a skincare routine for oily acne-prone skin?

This moisturizing treatment goes in the morning routine after your hydrating toner and before your sunscreen, and in the evening routine after your treatment and before bed. It works for oily skin by providing gentle hydration and a safe profile, though oily acne-prone skin needs ingredients focused on oil control and clearing blemishes.

### Can I use this cream with retinol, and in what order?

You can use this cream with retinol by applying your retinol first, letting it absorb, and then following with the cream. This moisturizer is unlikely to cause irritation on oily skin, but to properly care for acne-prone skin, a product of this type needs strong oil-controlling ingredients.

### How often should I use this cream?

You can use this moisturizing treatment twice daily to keep your oily skin hydrated and soft. This type of product needs stronger oil control ingredients to effectively manage breakouts for oily, acne-prone skin.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for oily acne-prone skin?

This cream is unlikely to cause irritation or breakouts on your oily skin, though it offers only moderate suitability. Oily acne-prone skin needs products with strong oil control ingredients to effectively manage blemishes.

### Can I use this cream around the eyes or on my body?

You can use this moisturizing treatment on your body and the thin skin around your eyes, as it is unlikely to cause irritation. To properly fit oily acne-prone skin, a product of this type needs ingredients that offer strong oil control for blemishes and breakouts.

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for oily acne-prone skin

- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/ae/p/cosrx/advanced-snail-96-mucin-power-essence/for/oily-acne-prone-skin) — Superior fit — AED 29.35 at Amazon
- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/ae/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/oily-acne-prone-skin) — Superior fit — AED 91.81 at Amazon
- [Torriden DIVE-IN Low Molecular Hyaluronic Acid Serum](https://lovi.care/skincare/ae/p/torriden/dive-in-low-molecular-hyaluronic-acid-serum/for/oily-acne-prone-skin) — Superior fit — AED 45.00 at Amazon

## Pairs well with

- Cleanser: [IS Clinical Cleansing Complex](https://lovi.care/skincare/ae/p/is-clinical/cleansing-complex/for/oily-acne-prone-skin) — Superior fit — AED 138.20 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/ae/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-acne-prone-skin) — Superior fit — AED 145.00 at Amazon
- SPF: [Dear, Klairs All-day Airy Sunscreen](https://lovi.care/skincare/ae/p/dear-klairs/all-day-airy-sunscreen/for/oily-acne-prone-skin) — Superior fit — AED 95.14 at Amazon

## Where to buy

No store in United Arab Emirates has a checked price for this product, so the page shows none.

## Ingredients

Sodium Hyaluronate, Acetyl Hexapeptide-8, Dipalmitoyl Hydroxyproline, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-5, Ceramide Eop, Ceramide Np, Squalane, Cimicifuga Racemosa Root Extract Black Cohosh Root Extract, Saccharomyces Lysate Extract, Glyceryl Polymethacrylate, Jojoba Seed Oil, Argania Spinosa Oil Argan Oil, Plukenetia Volubilis Seed Oil, Butyrospermum Parkii Butter Shea Butter, Cetyl Alcohol, Tocotrienols Vitamin E, Tocopheryl Linoleate, Sodium Carboxymethyl Beta-Glucan, Vitis Vinifera Seed Extract Grape Seed Extract, Oenothera Biennis Oil, Rosa Canina Oil Rosehip Oil, Proprietary Blend Essential Oil, Caprylyl Glycol, Ethylhexylglycerin, Undecylenoyl Glycine, Capryloyl Glycine
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/le-mieux/bio-cell-rejuvenating-cream/for/oily-acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/le-mieux/bio-cell-rejuvenating-cream/for/oily-acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/le-mieux/bio-cell-rejuvenating-cream/for/oily-acne-prone-skin
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- Singapore: https://lovi.care/skincare/sg/p/le-mieux/bio-cell-rejuvenating-cream/for/oily-acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/le-mieux/bio-cell-rejuvenating-cream/for/oily-acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/le-mieux/bio-cell-rejuvenating-cream/for/oily-acne-prone-skin (this page)