La Roche-Posay Toleriane Dermallergo Night Cream for acne-prone skin
Thermal Water
Niacinamide
Squalane
Shea Butter
AllantoinHigh
- HighCombination Skin Fit
- HighEffectiveness
- HighSafety
A great choice for acne-prone skin; a few moisturizers fit it even better.
This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Highly suitable for your combination skin, this formula leverages niacinamide for seboregulation and glycerin for humectant action, effectively balancing oil production and hydration. Salicylic acid also offers moderate benefits for your acne, blemishes, and breakouts by supporting skin health.
- The presence of shea butter and squalane further enhances barrier function and provides excellent moisturizing effects, contributing to overall skin resilience.
- The safety profile is excellent, with no risks of irritation due to the absence of prohibited or harsh ingredients.
How to apply
- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help keep breakouts under control.
- Apply after your cleanser and toner, and make sure to use your SPF right after in the morning.
- Gently spread a small amount of moisturizer over your face using soft motions. Let it absorb into the skin for a minute before getting dressed or applying makeup.
- Apply on slightly damp skin to help lock in extra moisture. This keeps your combination skin balanced without feeling heavy.
- Avoid the eye area and do a patch test before your first use. Stop using if you feel any irritation.
People Say
★4.2Overall rating based on 600+ reviewsUsers with ultra-sensitive, reactive, and allergy-prone skin frequently praise this night cream for its ability to instantly soothe redness and irritation without causing breakouts. While many appreciate the lightweight, gel-cream texture that absorbs quickly, those with extremely dry skin sometimes find it insufficiently moisturizing on its own, requiring an additional layer.
Highlights
Lightweight texture Mostly Mentioned
- “lightweight gel-cream”
- “feels like silk”
- “non-greasy finish”
Safe for sensitive skin Often Mentioned
- “no reaction”
- “fragrance-free formula”
Soothing and calming Often Mentioned
- “calms everything down”
- “skin felt calm”
- “reduced redness”
High price point Often Mentioned
- “expensive for size”
- “small bottle”
- “pricey”
Hygienic packaging Sometimes Noted
- “airtight pump”
- “hygienic dispenser”
- “dispenses perfect amount”
Not hydrating enough Sometimes Noted
- “need to layer”
- “not rich enough”
- “woke up dry”
Adverse reactions Rarely Noted
- “caused burning”
- “skin felt itchy”
- “awful reaction”
Texture issues Rarely Noted
- “sticky feel”
- “tacky finish”
- “sat on skin”
Sources: lovi.care, walmart.com, ulta.com, cultbeauty.co.uk, hometesterclub.com, lovelyskin.com, and more
Questions and answers
What makes Toleriane Dermallergo Night Cream a great fit for acne-prone skin?
This cream is a great fit because it balances oil production and keeps skin hydrated using niacinamide and glycerin. Ingredients like shea butter and squalane further help strengthen the skin barrier while offering great moisturizing effects with a very low risk of irritation.
Which ingredients make this cream a good fit for acne-prone skin?
This cream is a great fit for your skin because it features niacinamide to balance oil production along with squalane and shea butter to moisturize without feeling heavy. Its very safe formula is unlikely to cause any irritation.
What does Thermal Water do for acne-prone skin?
Thermal water helps calm acne-prone skin by reducing irritation, redness, and dryness while supporting the skin barrier. It is unlikely to cause irritation and may improve overall skin comfort when used alongside your regular acne routine.
The Medical Journal of Malaysia, 2024Dermatology and Therapy, 2023
What does Niacinamide do for acne-prone skin?
Niacinamide helps acne-prone skin by reducing both inflamed and uninflamed breakouts and calming redness. It is also very helpful for keeping oily skin balanced by cutting down on excess oil production, and it is well tolerated by most people.
Where does it go in a skincare routine for acne-prone skin?
This moisturizing treatment is used at the end of your evening routine after your treatment step, and also as the final step in your morning routine before sunscreen. It helps hydrate and balance your skin while keeping the barrier strong, with virtually no risk of irritation.
International Journal of Cosmetic Science, 2020Clinical, Cosmetic and Investigational Dermatology, 2017
Can I use this cream with retinol, and in what order?
You can use this moisturizing treatment with retinol by applying the cream after your retinol step to help keep your skin calm and hydrated. This type of routine helps lower the chance of dryness and irritation while you use active treatments.
How often should I use it?
You can use this moisturizing treatment daily in your evening routine. Regular application helps keep acne-prone skin balanced and hydrated without causing irritation.
Journal of Cosmetic Dermatology, 2020Health Science Reports, 2021
Can this cream clog pores, cause breakouts or purging for acne-prone skin?
This cream is a great fit for acne-prone skin because it balances oil production and hydration while supporting the skin barrier with ingredients like niacinamide, squalane, and shea butter. It has an excellent safety profile without harsh ingredients, so it is unlikely to cause irritation or breakouts.
Can I use it around the eyes or on my body?
This cream suits the thin skin around your eyes and your body well because its gentle ingredients keep the skin calm and safe from irritation. It is unlikely to cause any problems in these sensitive areas, maintaining good moisture without harsh effects.
Is this cream fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events.
Lasers in Medical Science, 2025Balneotherapy with thermal water altered specific skin microbiota at genus and species levels in healthy female volunteers compared to tap water, which produced no significant microbiome changes.
Life, 2023Malaysian thermal spring water as an adjunct to standard acne therapy improved skin hydration, reduced dryness and stinging, enhanced overall tolerability, and improved the acne disability index in patients with mild to moderate acne.
The Medical Journal of Malaysia, 2024A 2% Sphingomonas xenophaga ferment extract cream applied twice daily for 4 weeks significantly decreased facial vascular disorder scores compared to vehicle in 86 Caucasian female subjects, alongside dose-dependent inhibition of pre-kallikrein activity in vitro.
International Journal of Cosmetic Science, 2025Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.
Journal of Cosmetic Dermatology, 2021Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.
The Journal of Investigative Dermatology, 2008Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.
Dermatologic Surgery, 2005Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts.
Molecules, 2025Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway.
Antioxidants, 2025A skin barrier restoring cream with shea butter, silkflo, and vitamin E increased type I procollagen synthesis, enhanced antioxidant enzyme activity, decreased reactive oxygen species generation, and promoted hyaluronic acid production in H2O2-stimulated human keratinocyte cells compared to untreated cells.
International Journal of Cosmetic Science, 2025Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel.
Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo.
Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment.
Aesthetic Plastic Surgery, 2018
Ingredients
Water, Glycerin, Butylene Glycol, Propanediol, Butyrospermum Parkii Butter, Shea Butter, Pentylene Glycol, Squalane, Niacinamide, Ammonium Polyacryloyldimethyl Taurate, Pyridoxine Hcl, Polysorbate 20, Zea Mays Starch, Salvia Miltiorrhiza Root Extract, Allantoin, Glyceryl Acrylate, Acrylic Acid Copolymer, Sodium Hydroxide, Sphingomonas Extract Ferment, Hydroxyacetophenone, Caprylyl Glycol, Citric Acid, Trisodium Ethylenediamine Disuccinate, Acetyl Dipeptide-1 Cetyl Ester, Xanthan Gum, Tocopherol
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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