La Roche-Posay Toleriane Dermallergo Crème for acne-prone skin
Glycerin
Squalane
Niacinamide
Butyrospermum Parkii Butter Shea Butter
Hyaluronic AcidAverage
- AverageCombination Skin Fit
- AverageEffectiveness
- HighSafety
Works for acne-prone skin; other moisturizers fit it better.
This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate moisturizing for your combination skin, as glycerin and hyaluronic acid hydrate and enhance barrier resilience, while niacinamide supports anti-inflammatory and sebum-regulating functions beneficial for acne and blemishes.
- The formula provides relevant benefits for your acne and breakouts due to niacinamide's anti-inflammatory properties, though it lacks sufficient ingredients for optimal oil control on your oily areas.
- The product is safe for your combination skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.
How to apply
- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help keep breakouts under control.
- Apply after your cleanser and toner, and make sure to use your SPF right after in the morning.
- Gently spread a small amount of moisturizer over your face using soft motions. Let it absorb into the skin for a minute before getting dressed or applying makeup.
- Apply on slightly damp skin to help lock in extra moisture. This keeps your combination skin balanced without feeling heavy.
- Avoid the eye area and do a patch test before your first use. Stop using if you feel any irritation.
People Say
★4.3Overall rating based on 900+ reviewsUsers with dry, ultra-sensitive, and allergy-prone skin frequently praise this product for its deep hydration and immediate soothing of redness and irritation. It is also often noted as being safe for sensitive skin and absorbing quickly. Some users find the quantity to be small for the price and the packaging can be frustrating to empty completely.
Highlights
Calms redness Mostly Mentioned
- “really calms irritated skin”
- “itchiness... has disappeared. Naturally, it also reduced redness”
- “calms my skin down”
- “reduces irritation and counteracts redness”
Deeply hydrating Often Mentioned
- “The hydration is fantastic”
- “deeply hydrated with no deep dryness”
- “provides sufficient moisture throughout the day”
- “provides up to 48 hours of hydration”
Safe for sensitive skin Often Mentioned
- “apply this to my super sensitive skin without any side effects”
- “perfect day cream for those with hyper-allergic skin”
- “need things as sensitive as baby products... this is really beautiful”
- “use without irritation”
Absorbs quickly Sometimes Noted
- “soaks into the skin immediately”
- “Absorbs quickly and well”
- “absorbs quickly, makeup application is no problem”
- “works great under make up”
Expensive for quantity Sometimes Noted
- “quantity is too small for the price”
- “small size means it's not the most cost-effective”
- “get way less product for a higher price”
- “Expensive but wonderful stuff”
Can feel drying Rarely Noted
- “Quite drying and don't go far”
- “forehead feels quite flaky”
- “causing my skin to dry out”
Causes pilling Rarely Noted
- “Overapplying can result in pilling”
- “similar to dead skin cells rolling off”
- “need to use a lot... small pump doesn't go far”
Frustrating packaging Rarely Noted
- “stored in a compressed pouch... can't use every last bit”
- “Prefer a tube to avoid waste”
- “packaging is frustrating”
Sources: lovi.care, walmart.com, facethefuture.co.uk, hwahae.com, my-origines.com, deloox.com, and more
Questions and answers
How well does La Roche-Posay Toleriane Dermallergo Crème work for acne-prone skin?
La Roche-Posay Toleriane Dermallergo Crème works moderately well for acne-prone skin, as glycerin and hyaluronic acid hydrate while niacinamide helps calm breakouts. However, it lacks sufficient ingredients for optimal oil control on oily areas. A moisturizer for this skin needs effective ingredients that provide excellent benefits for acne and blemishes, oil-controlling agents, soothing extracts, and zero risk of irritation.
Which ingredients make this cream a good fit for acne-prone skin?
Glycerin and hyaluronic acid help hydrate and support the skin barrier, while niacinamide helps calm blemishes. This skin type needs a moisturizer that also provides strong oil control with targeted ingredients for breakouts.
What does Glycerin do for acne-prone skin?
Glycerin helps keep acne-prone skin hydrated and calm without clogging pores or feeling heavy. It supports the skin barrier so it stays soft and smooth while handling everyday treatments.
The British Journal of Dermatology, 2008International Journal of Toxicology, 2019
What does Squalane do for acne-prone skin?
Squalane may help keep acne-prone skin soft and smooth, but peroxidated forms can trigger inflammation in skin cells. For a better fit on acne-prone skin, products need non-clogging, soothing ingredients that balance oil without causing irritation.
Where does this cream go in a skincare routine for acne-prone skin?
This cream goes toward the end of your routine, right before sunscreen in the morning and as the final step in the evening. It provides moderate hydration for your skin while helping calm breakouts, though acne-prone skin of this type needs extra oil-control ingredients to manage shine on oily areas.
International Journal of Cosmetic Science, 2020Clinical, Cosmetic and Investigational Dermatology, 2017
Can I use it with retinol, and in what order?
You can use this moisturizer with retinol, and it works best when applied after your retinol treatment to help keep your skin calm and hydrated. Clinical studies show that using a barrier-supporting moisturizer alongside retinoids helps reduce dryness and irritation while supporting your overall routine.
How often should I use this cream?
You can use this moisturizer daily in your morning and evening skincare routines. Daily applications help keep skin hydrated and support your skin barrier.
Can it clog pores, cause breakouts or purging for acne-prone skin?
This moisturizer works for acne-prone skin, but it lacks sufficient ingredients for optimal oil control on oily areas. An average fit for acne-prone skin needs lightweight hydration, oil-balancing ingredients, and clear pores.
Can I use this cream around the eyes or on my body?
You can use this cream on the thin skin around your eyes and on your body, as its gentle ingredients are generally well tolerated across different areas. An acne-prone body or eye routine also needs lightweight, oil-balancing ingredients to keep pores clear.
Is it fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.
Journal of Cosmetic Dermatology, 2020Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.
International Journal of Cosmetic Science, 2001Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.
Journal of Drugs in Dermatology, 2012Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts.
Molecules, 2025Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway.
Antioxidants, 2025Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.
Journal of Cosmetic Dermatology, 2021Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.
The Journal of Investigative Dermatology, 2008Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.
Dermatologic Surgery, 2005A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events.
Lasers in Medical Science, 2025A skin barrier restoring cream with shea butter, silkflo, and vitamin E increased type I procollagen synthesis, enhanced antioxidant enzyme activity, decreased reactive oxygen species generation, and promoted hyaluronic acid production in H2O2-stimulated human keratinocyte cells compared to untreated cells.
International Journal of Cosmetic Science, 2025Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019
Why other moisturizers fit acne-prone skin better
A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions.
Journal of Cosmetic Dermatology, 2024Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components.
Molecules, 2023
Ingredients
Water, Glycerin, Squalane, Pentylene Glycol, Butylene Glycol, Propanediol, Dimethicone, Niacinamide, Butyrospermum Parkii Shea Butter, Hyaluronic Acid, Polysorbate 20, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Caprylyl Glycol, Citric Acid, Tocopherol, Ethylhexylglycerin, Sodium Hydroxide
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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