# iS Clinical Brightening Complex for oily acne-prone skin

**Lovi Fit: Average fit for oily acne-prone skin.**
Oily Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/ae/p/is-clinical/brightening-complex/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Arab Emirates.

Brand: [iS Clinical](https://lovi.care/skincare/ae/brands/is-clinical)
Category: [Serums and treatments](https://lovi.care/skincare/ae/best/serums)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily acne-prone skin; other serums fit it better.

## Why this fit

- Offers moderate brightening and smoothing for your oily skin due to alpha-arbutin and saccharum officinarum extract, which help even skin tone and exfoliate.
- While Willow Bark Extract and Saccharum Officinarum Extract Extrait De Canne À Sucre Extract are highly suitable for oily skin by regulating desquamation, ingredients like Sodium Hyaluronate and Glycerin provide hydration that is not directly targeted at your acne concerns.
- The product is safe for your oily skin with no risks of irritation due to the absence of harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ae/p/is-clinical/brightening-complex/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ae/p/is-clinical/brightening-complex/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/ae/p/is-clinical/brightening-complex/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/ae/p/is-clinical/brightening-complex/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/ae/p/is-clinical/brightening-complex/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/ae/p/is-clinical/brightening-complex/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/ae/p/is-clinical/brightening-complex/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/ae/p/is-clinical/brightening-complex/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/ae/p/is-clinical/brightening-complex/for/oily-acne-prone-skin): Average (this page)

## Key ingredients

Sodium Hyaluronate, Alpha-Arbutin, Licorice Root Extract, Tetrahexyldecyl Ascorbate, Willow Bark Extract

## What the research says

- Combined sequential treatment with microneedling and 35% glycolic acid peels caused a significant improvement in superficial and moderately deep acne scars, skin texture, and postacne pigmentation in thirty patients compared to thirty patients receiving microneedling alone. ([Journal of Cosmetic Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22151943/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- A botanical face cleanser with hops and willow bark extract continuously reduced skin sebum levels without reactive seborrhea after treatment in 21 healthy volunteers compared to a sodium laureth sulfate cleanser, with neither cleanser causing skin irritation. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30022595/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- A non-hydroquinone topical formulation (SKNB19) improved hyperpigmentation by 28.5% in patient self-assessment and 27% in independent reviewer assessment compared with 4% hydroquinone in 18 adult subjects, while showing significantly less irritation and better tolerability. ([Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/33022197/))
- Encapsulation of alpha arbutin in an optimized ethosomal gel significantly improved skin melanin reduction, moisture content, and elasticity in human volunteers compared to conventional formulations. ([Heliyon, 2023](https://pubmed.ncbi.nlm.nih.gov/37681127/))
- Combining a home-based radiofrequency device and arbutin cream reduced mMASI scores by 25.6% and melanin index by 22.8% at 8 weeks compared to baseline in 38 participants. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/39918262/))
- Combining 755 nm alexandrite laser with topical licorice gel significantly reduces terminal hair counts compared to alexandrite laser with placebo in women with idiopathic hirsutism. ([Evidence-based Complementary and Alternative Medicine, 2015](https://pubmed.ncbi.nlm.nih.gov/26273313/))
- Licochalcone A activated Nrf2 signaling, elevated cytoprotective enzymes, increased the reduced-to-oxidized glutathione ratio, and decreased reactive oxygen species in human fibroblasts and neutrophils, while a LicA-rich licorice extract lowered UVA-induced oxidative processes in vivo. ([Experimental Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25381913/))
- Bioactive glycyrrhizic acid and oxymatrine ionic liquid self-assembled nanomicelles significantly promoted the transdermal permeation, subcutaneous retention, and anti-photoaging efficacy of palmitoyl pentapeptide-4 in cellular and animal models compared to unformulated peptide. ([Advanced Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39783908/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Bioactive lipid nanocarriers co-loaded with willow bark or ivy leaf extracts and UV-filters provided pronounced UVA photoprotection up to an SPF-equivalent value of 13 and a maximum in vivo skin hydration effect of 97% when prepared with pomegranate oil. ([Nanomaterials, 2022](https://pubmed.ncbi.nlm.nih.gov/35889587/))
- A topical serum containing 0.5% salicin applied twice daily reduced visible signs of skin aging, including wrinkles and tactile roughness, in 30 female subjects over 12 weeks compared to baseline. ([Journal of Cosmetic Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/20883292/))
- A novel emulsion containing niacinamide, lens esculenta seed extract, and white willow bark extract effectively improved acne, blackheads, and conspicuous facial pores in 30 subjects with oily skin. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38140770/))

## Why other serums fit oily acne-prone skin better

- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo. ([BioMed Research International, 2022](https://pubmed.ncbi.nlm.nih.gov/35342760/))

## What reviewers say

Based on limited data, this product is highly praised for its ability to fade dark spots and hyperpigmentation, leading to a more even and radiant skin tone. Users with various skin types, including acne-prone and sensitive skin, find the formula to be gentle and non-irritating. A moderate number of users mention the high price point as a drawback, while a low frequency of reviews indicate no visible changes.

- Liked: Fades dark spots (mostly mentioned)
- Liked: Evens skin tone (often mentioned)
- Liked: Gentle and non-irritating (sometimes noted)
- Disliked: High price point (sometimes noted)
- Disliked: No visible changes (rarely noted)
- Disliked: Unpleasant smell (rarely noted)

## How to apply

- Could be used as part of your PM routine. Start 3 times a week and build up to daily use if your skin tolerates it well.
- Apply your serum after cleansing and toning, but before putting on your moisturizer.
- Gently press 2 to 3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on clean, dry skin to help manage your blemishes safely.
- Do a patch test before your first use and avoid the delicate eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Brightening Complex work for oily acne-prone skin?

Brightening Complex works moderately well for oily acne-prone skin, offering safe brightening and smoothing with a low risk of irritation. A treatment for this skin needs ingredients like niacinamide, propolis, or vitamin C to better target acne and excess oil while keeping hydration balanced.
Sources: [Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30022595/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this cream a good fit for oily acne-prone skin?

Willow bark extract and alpha-arbutin make this cream a good fit for oily acne-prone skin by helping to regulate shedding and even out skin tone. To work best for this skin type, a product of this type needs effective ingredients like niacinamide, propolis, or vitamin C that target both acne and excess oil without any risk of irritation.
Sources: [Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30022595/)

### What does Hyaluronic Acid do for oily acne-prone skin?

Hyaluronic acid helps calm oily acne-prone skin by reducing sebum production and lipid synthesis in sebaceous glands. It also supports skin barrier function and improves hydration while helping deliver treatments without causing irritation.
Sources: [The Journal of Investigative Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28163068/), [Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35796638/)

### What does Alpha-Arbutin do for oily acne-prone skin?

Alpha-arbutin does not target acne or oiliness directly, but it helps fade dark spots left behind by breakouts on oily skin. Because it works gently, it is unlikely to clog pores or trigger new pimples while evening out your skin tone. Oily, acne-prone skin still needs ingredients that clear pores and calm redness to fully address breakouts alongside dark spots.

### Where does it go in a skincare routine for oily acne-prone skin?

This treatment goes in the evening routine. A product of this type needs acne-fighting ingredients like salicylic acid or benzoyl peroxide to properly care for oily, acne-prone skin.

### Can I use this cream with retinol, and in what order?

This treatment is unlikely to irritate your oily skin, so you may use it alongside retinol, applying your retinol first and following with this cream. Because this skin needs ingredients that directly target breakouts and keep pores clear, an ideal product of this type should also include acne-fighting components.

### How often should I use it?

You can use this treatment in the evening as part of your nighttime routine. For oily acne-prone skin, an average fit product of this type needs targeted blemish-clearing and pore-refining ingredients alongside oil control to work best.

### Can this cream clog pores, cause breakouts or purging for oily acne-prone skin?

This cream is unlikely to clog pores or cause breakouts for oily acne-prone skin, as it is safe and free of harsh ingredients that typically trigger irritation. However, it features hydrating ingredients like sodium hyaluronate and glycerin that are not directly targeted at acne concerns. To better care for oily acne-prone skin, this type of product needs pore-clearing and oil-balancing ingredients like willow bark extract and fruit extracts to manage breakouts.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30022595/)

### Is it fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Stearyl alcohol and cetearyl alcohol are fatty alcohols, which soften the skin.

## Alternatives for oily acne-prone skin

- [Clinique Fresh Pressed Daily Booster with Pure Vitamin C 10%](https://lovi.care/skincare/ae/p/clinique/fresh-pressed-daily-booster-with-pure-vitamin-c-10/for/oily-acne-prone-skin) — Superior fit — AED 365.22 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/ae/p/neogen-dermalogy/real-vitamin-c-serum/for/oily-acne-prone-skin) — Superior fit — AED 89.30 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/ae/p/neogen-dermalogy/real-vita-c-serum/for/oily-acne-prone-skin) — High fit — AED 89.30 at Amazon

## Pairs well with

- Cleanser: [IS Clinical Cleansing Complex](https://lovi.care/skincare/ae/p/is-clinical/cleansing-complex/for/oily-acne-prone-skin) — Superior fit — AED 138.20 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/ae/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-acne-prone-skin) — Superior fit — AED 145.00 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/ae/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/oily-acne-prone-skin) — Superior fit — AED 33.40 at Amazon

## Where to buy

No store in United Arab Emirates has a checked price for this product, so the page shows none.

## Ingredients

Water, Willow Bark Extract, Sodium Hyaluronate, Saccharum Officinarum Extract Extrait De Canne À Sucre Extract, Vaccinium Myrtillus Leaf Extract Fruit, Ascophyllum Nodosum Extract, Tetrahexyldecyl Ascorbate, Glycerin, Squalane, Imperata Cylindrica Root Extract, Glyceryl Stearate, Alpha-Arbutin, Peg-100 Stearate, Peg-8 Smdi Copolymer, Triethanolamine, Polyporus Umbellatus Extract Mushroom Extract, Stearyl Alcohol, Cetearyl Alcohol, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Dimethicone, 1,2-Hexanediol, Caprylyl Glycol, Citrus Aurantium Dulcis Oil, Xanthan Gum, Hydrogenated Lecithin, Disodium Edta
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/is-clinical/brightening-complex/for/oily-acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/is-clinical/brightening-complex/for/oily-acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/is-clinical/brightening-complex/for/oily-acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/is-clinical/brightening-complex/for/oily-acne-prone-skin
- France: https://lovi.care/skincare/fr/p/is-clinical/brightening-complex/for/oily-acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/is-clinical/brightening-complex/for/oily-acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/is-clinical/brightening-complex/for/oily-acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/is-clinical/brightening-complex/for/oily-acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/is-clinical/brightening-complex/for/oily-acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/is-clinical/brightening-complex/for/oily-acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/is-clinical/brightening-complex/for/oily-acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/is-clinical/brightening-complex/for/oily-acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/is-clinical/brightening-complex/for/oily-acne-prone-skin (this page)