# Image Skincare the MAX™ Stem Cell Serum for mature skin

**Lovi Fit: High fit for mature skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/ae/p/image-skincare/the-maxtm-stem-cell-serum/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Arab Emirates.

Brand: [Image Skincare](https://lovi.care/skincare/ae/brands/image-skincare)
Category: [Serums and treatments](https://lovi.care/skincare/ae/best/serums)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for mature skin; a few serums fit it even better.

## Why this fit

- Offers high suitability for your normal skin, as Sodium Hyaluronate and Tocopheryl Acetate provide essential hydration and antioxidant protection, complementing the anti-aging benefits of Acetyl Hexapeptide-8 and Palmitoyl Tripeptide-38 for wrinkle reduction.
- The inclusion of Camellia Sinensis Leaf Extract and Centella Asiatica Extract further supports skin health by offering soothing properties, which is beneficial for maintaining overall skin comfort.
- The product is safe for your skin, with no identified risks of irritation due to the absence of harsh ingredients and the presence of calming botanical extracts.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ae/p/image-skincare/the-maxtm-stem-cell-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ae/p/image-skincare/the-maxtm-stem-cell-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/ae/p/image-skincare/the-maxtm-stem-cell-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/ae/p/image-skincare/the-maxtm-stem-cell-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/ae/p/image-skincare/the-maxtm-stem-cell-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/ae/p/image-skincare/the-maxtm-stem-cell-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ae/p/image-skincare/the-maxtm-stem-cell-serum/for/mature-skin): High (this page)
- [Dry sensitive skin](https://lovi.care/skincare/ae/p/image-skincare/the-maxtm-stem-cell-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/ae/p/image-skincare/the-maxtm-stem-cell-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Pyrus Malus Extract Cell Fruit Culture, Sodium Hyaluronate, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Tetrahexyldecyl Ascorbate

## What the research says

- Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group. ([American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/))
- Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days. ([Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/))
- Argireline applied twice daily for 4 weeks achieved a total anti-wrinkle efficiency of 48.9% and notably reduced wrinkle depth compared to placebo in Chinese subjects. ([Journal of Cosmetic and Laser Therapy, 2013](https://pubmed.ncbi.nlm.nih.gov/23607739/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- A 3-in-1 anti-aging topical night serum-in-oil applied once daily decreased wrinkles by 11%, increased skin firmness by 8%, reduced redness by 70%, and improved overall skin quality and complexion in 103 female subjects over 28 to 84 days compared to baseline. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30924254/))
- A novel facial serum containing apple stem cell extract, pro-collagen lipopeptide, creatine, and urea improved mitochondrial function in human senescent cultured fibroblasts and demonstrated anti-wrinkle, dermal density, and skin elasticity benefits in 32 women with sensitive skin applied twice daily for 28 days compared to baseline. ([Journal of Cosmetic Dermatology, 2016](https://pubmed.ncbi.nlm.nih.gov/26424007/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Acetyl hexapeptide-3 and tripeptide-10 citrulline demonstrated antiwrinkle efficacy and decreased transepidermal water loss in twenty-four healthy volunteers compared to control groups, though synergistic effects between the two peptides remained unclear. ([Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28150423/))
- Daily topical acetyl hexapeptide-8 showed a trend toward a longer time until return to baseline Jankovic Blepharospasm Rating Scale scores compared to placebo (3.7 months vs. 3.0 months) in 24 patients with blepharospasm receiving botulinum toxin therapy. ([European Journal of Neurology, 2013](https://pubmed.ncbi.nlm.nih.gov/23146065/))
- Dissolving microneedles loaded with 3-O-ethyl ascorbic acid and acetyl hexapeptide-8 achieved higher cumulative transdermal delivery than aqueous solutions and significantly reduced photoaging signs while restoring oxidative balance in a UV/D-galactose-induced mouse model. ([International Journal of Biological Macromolecules, 2026](https://pubmed.ncbi.nlm.nih.gov/41628877/))
- A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo. ([Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/))
- Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants. ([Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/))
- Palmitoyl tetrapeptide-7, acetyl hexapeptide-8, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-10 significantly increased type III collagen levels in human dermal fibroblasts following UV exposure, with their combination demonstrating a greater effect in vitro and enhancing type I, III, and IV collagen levels in ex vivo skin tissues compared to individual components. ([International Journal of Cosmetic Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42683869/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))

## What reviewers say

Users with mature, dry, or environmentally stressed skin frequently praise this serum for its hydrating, firming, and smoothing effects, which target fine lines and improve elasticity for a more youthful appearance. Some users note that consistent, long-term use is necessary to see the full benefits.

- Liked: Firms and tightens (often mentioned)
- Liked: Reduces fine lines (often mentioned)
- Liked: Absorbs quickly (sometimes noted)
- Liked: Hydrates and smooths (sometimes noted)
- Disliked: High price point (sometimes noted)
- Disliked: Faulty pump (rarely noted)
- Disliked: Slow to show (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes IMAGE Skincare The MAX Stem Cell Serum a great fit for mature skin?

IMAGE Skincare the MAX Stem Cell Serum is a great fit for mature skin because it combines sodium hyaluronate and plant extracts that provide deep hydration and soothing benefits. It also features peptides and vitamin C derivatives to help smooth out wrinkles and keep the skin looking firm.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/)

### Which ingredients make this serum a good fit for mature skin?

This serum is a great fit for mature skin because Sodium Hyaluronate and Tocopheryl Acetate provide essential hydration, while Acetyl Hexapeptide-8 and Palmitoyl Tripeptide-38 help reduce wrinkles. These ingredients work together to smooth lines and keep your skin feeling soft and comfortable.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/)

### What does Apple Fruit Cell Culture Extract do for mature skin?

Apple fruit cell culture extract helps improve fine lines, skin firmness, and elasticity while supporting tired cells in mature skin. Using a serum with this ingredient twice a day helps smooth the skin and keeps it looking youthful.
Sources: [Journal of Cosmetic Dermatology, 2016](https://pubmed.ncbi.nlm.nih.gov/26424007/)

### What does Hyaluronic Acid do for mature skin?

Hyaluronic acid helps mature skin by deeply boosting moisture, improving elasticity, and smoothing the appearance of fine lines and wrinkles. Regular use keeps the skin looking plump and soft while supporting overall firmness and hydration.
Sources: [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/), [Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38591218/)

### Where does this serum go in a skincare routine for mature skin?

This treatment serum goes in the evening routine after cleansing and before moisturizing, which keeps things simple and safe around sun exposure. Some active serums can also be used in the morning or twice a day.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying your retinol first and following with this treatment to keep your skin smooth and comfortable. This product is unlikely to cause irritation because it contains calming botanical extracts and lacks harsh ingredients, helping to buffer the drying effects of a retinoid.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/), [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/)

### How often should I use this serum?

Apply this serum in your evening routine, using it as a step after cleansing and before moisturizing. This frequency helps support mature skin with anti-aging benefits while maintaining a safe routine.
Sources: [Facial Plastic Surgery, 2014](https://pubmed.ncbi.nlm.nih.gov/24488631/), [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/)

### Can this serum clog pores, cause breakouts or purging for mature skin?

This serum is unlikely to clog pores, cause breakouts, or lead to purging on mature skin. It features a safe formula with calming plant extracts and hydrating ingredients that help maintain skin comfort without harsh irritants.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for mature skin

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/ae/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/mature-skin) — Superior fit — AED 347.75 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/ae/p/skinceuticals/c-e-ferulic/for/mature-skin) — Superior fit — AED 715.99 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/ae/p/neogen-dermalogy/real-vita-c-serum/for/mature-skin) — High fit — AED 89.30 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ae/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — AED 84.53 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/ae/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — AED 65.43 at Amazon
- Moisturizer: [Elizabeth Arden Ceramide Lift and Firm Night Cream](https://lovi.care/skincare/ae/p/elizabeth-arden/advanced-ceramide-lift-and-firm-night-cream/for/mature-skin) — Superior fit — AED 493.00 at Amazon

## Where to buy

No store in United Arab Emirates has a checked price for this product, so the page shows none.

## Ingredients

Water, Acetyl Hexapeptide-8, Sucrose Palmitate, Polysorbate 20, Tocopheryl Acetate, Pyrus Malus Extract Cell Fruit Culture, Plankton Extract, Sodium Hyaluronate, Hydrolyzed Rice Bran Protein, Imperata Cylindrica Root Extract, Tetrahexyldecyl Ascorbate, Palmitoyl Tripeptide-1, Algae Extract, Camellia Sinensis Leaf Extract, Spiraea Ulmaria Flower Extract, Centella Asiatica Extract, Echinacea Purpurea Extract, Phaseolus Radiatus L Callus Extract, Acetyl Octapeptide-3, Leontopodium Alpinum Meristem Cell Culture, Macrocystis Pyrifera Extract, Argania Spinosa Extract Cell Sprout Culture, Superoxide Dismutase, Palmitoyl Tripeptide-38, Hydroxypropyl Cyclodextrin, Hydrolyzed Wheat Protein, Arabidopsis Thaliana Extract, Lecithin, Butylene Glycol, Peg-8 Smdi Copolymer, Pullulan, Glycine Soja Protein Soybean Protein, Isomalt, Propylene Glycol, Glyceryl Polymethacrylate, Sodium Dextran Sulfate, Citric Acid, Pvp, Disodium Edta, Xanthan Gum, Sodium Benzoate, Potassium Sorbate, Hydroxyethylcellulose, Phenoxyethanol, Ethylhexylglycerin
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

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- United Arab Emirates: https://lovi.care/skincare/ae/p/image-skincare/the-maxtm-stem-cell-serum/for/mature-skin (this page)
