Illiyoon Ceramide Ato Concentrate Cream for acne-prone skin

How to apply

Questions and answers

What the research says

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• Topical application of an emulsion containing a complete mixture of ceramides III, IIIB, VI, phytosphingosine, cholesterol, and linoleic acid significantly accelerated barrier recovery after SLS damage and improved skin hydration after acetone treatment in human volunteers compared to an emulsion containing only two types of ceramides.

  Journal of the European Academy of Dermatology and Venereology, 2002

• Phytosphingosine demonstrates anti-microbial and anti-inflammatory activity with excellent clinical results in acne vulgaris.

  International Journal of Cosmetic Science, 2007

• Enzyme-modified ginseng extract cream significantly reduced the global photo-damage score and various roughness measures including total roughness, smoothness depth, and arithmetic roughness average compared to placebo in 23 human subjects.

  Rejuvenation Research, 2015

• A red ginseng hydrogel formulation with 1,2-hexanediol promoted selective growth of Staphylococcus epidermidis and decreased Cutibacterium acnes in 20 female subjects.

  Journal of Ginseng Research, 2022

• A 1% fermented black ginseng cream significantly reduced eye wrinkles and brightened skin color in twenty-three human subjects compared to control cream and baseline.

  Journal of Toxicology and Environmental Health. Part A, 2020

• Botulinum toxin-A encapsulated in phosphatidylcholine/cholesterol nanoliposomes delivered transdermally achieved a diffusion depth of 380 μm and showed a nonsignificant advantage in relieving post-acne scarring compared to hyaluronic acid hydrogel treatment in 12 facial patients.

  Journal of Materials Science. Materials in Medicine, 2024

• Topical application of cholesterol sulfate increases stratum corneum thickness and inhibits protease-induced cell dissociation by competitively inhibiting serine proteases in mice and human stratum corneum.

  The Journal of Investigative Dermatology, 1998

• Topical lovastatin treatment impairs the recovery of cutaneous permeability barrier function and stratum corneum cholesterol levels after acetone disruption in mice, an effect normalized by simultaneous treatment with mevalonate or cholesterol.

  The Journal of Clinical Investigation, 1990

• Topical application of a cream containing the NHE1 activator rosmarinic acid decreased skin surface pH and transepidermal water loss while increasing skin hydration in 50-60-year-old adult females compared to vehicle cream and no treatment.

  International Journal of Molecular Sciences, 2022

• Emulgels containing Perilla frutescens seed oil, Moringa oleifera seed oil, and mixed seed oil microemulsions exhibit good stability, lack of cytotoxicity in PBMC, and no skin irritation or allergic reactions in human subjects.

  Polymers, 2022

• Incorporating rosmarinic acid into sunscreens enhanced the in vivo SPF of octocrylene by over 157% and reduced lipid peroxidation in the human stratum corneum.

  Antioxidants, 2025

Why other moisturizers fit acne-prone skin better

• Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components.

  Molecules, 2023

• A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions.

  Journal of Cosmetic Dermatology, 2024

• A facial serum containing snail secretion filtrate, Calendula officinalis, and Glycyrrhiza glabra root extract significantly reduced inflammatory acne lesions compared to placebo in 66 participants with mild-to-moderate maskne over 12 weeks.

  Journal of Cosmetic Dermatology, 2022

Ingredients

Water, Butylene Glycol, Glycerin, Cetyl Ethylhexanoate, Pentaerythrityl Tetraisostearate, Cyclopentasiloxane, Stearic Acid, Palmitic Acid, Behenyl Alcohol, Arachidyl Alcohol, C14-22 Alcohols, Cyclohexasiloxane, Hydroxypropyl Bispalmitamide Mea, Arachidyl Glucoside, C12-20 Alkyl Glucoside, Polyacrylate-13, Dimethiconol, Mannitol, Glyceryl Caprylate, Polyisobutene, Panax Ginseng Water Root, Ethylhexylglycerin, Acrylates Ammonium Methacrylate Copolymer, Polysorbate 20, Sorbitan Isostearate, Myristic Acid, Arachidic Acid, Bupleurum Falcatum Root Extract, Angelica Acutiloba Root Extract, Ophiopogon Japonicus Root Extract, Glucose, Cholesterol, Silica, Perilla Ocymoides Seed Extract, Tocopherol, Ceramide Np, Phytosphingosine, Hydrogenated Lecithin, Canola Oil, Rosmarinus Officinalis Leaf Extract Rosemary Leaf Extract

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.