HydroPeptide Power Serum for oily acne-prone skin
Palmitoyl Tripeptide-5
Hexapeptide-11
Acetyl Hexapeptide-30
Sodium Hyaluronate
Lemon Peel Extract
High
- HighOily Skin Fit
- HighEffectiveness
- ExcellentSafety
A great choice for oily acne-prone skin; a few serums fit it even better.
This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- This formulation is highly suitable for your oily skin, as Barosma Betulina Leaf Extract and Hexapeptide-11 work synergistically to regulate sebum production and condition the skin, addressing your concerns with acne, blemishes, and breakouts. Tetrahexyldecyl Ascorbate further aids in brightening your skin tone and smoothing texture, offering relevant benefits for your skin issues.
- The inclusion of Tocopherol and Glycerin ensures a gentle experience, minimizing irritation potential for your oily skin.
- This product is safe for your skin.
How to apply
- Could be used as part of your PM routine. Start 3 times a week and build up to daily use if your skin tolerates it well.
- Apply your serum after cleansing and toning, but before putting on your moisturizer.
- Gently press 2 to 3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on clean, dry skin to help manage your blemishes safely.
- Do a patch test before your first use and avoid the delicate eye area.
People Say
★4.8Overall rating based on 400+ reviewsUsers consistently praise this serum as a lightweight, non-greasy anti-aging powerhouse that visibly plumps and smooths the skin. While it is highly effective for hydrating dry skin and softening fine lines without irritating sensitive complexions, the high price point and distinct scent are occasional points of contention.
Highlights
Lightweight texture Mostly Mentioned
- “sinks right into skin”
- “featherlight formula”
- “perfect under makeup”
- “no greasy residue”
Deep hydration Often Mentioned
- “skin feels incredibly soft”
- “visibly plumps”
- “deeply hydrates without heaviness”
- “glowing complexion”
Visible anti-aging Often Mentioned
- “fine lines look reduced”
- “skin feels firmer”
- “years-younger appearance”
- “unbelievable difference in 2 weeks”
High price point Often Mentioned
- “a little pricey”
- “worth the occasional splurge”
- “wallet hurting”
Gentle on skin Sometimes Noted
- “doesn't irritate my sensitive skin”
- “calming peptides”
- “no redness or breakouts”
- “gentle formula”
Pleasant scent Sometimes Noted
- “smells like heaven”
- “hint of grapefruit”
- “light and refreshing”
- “smells like cucumbers”
Packaging size Rarely Noted
- “1oz is too small”
- “wish it was bigger”
- “pump stopped working”
- “expensive for the size”
Scent dislike Rarely Noted
- “smell is a little off-putting”
- “can't stand the scent”
- “smells terrible”
- “fragrance isn't for everyone”
Slow results Rarely Noted
- “didn't see dramatic results”
- “no huge difference”
- “takes consistent use”
- “wrinkles still there”
Sources: lovi.care, hydropeptide.com, dermstore.com, lovelyskin.com, youtube.com, wimj.com, and more
Questions and answers
What makes Power Serum a great fit for oily acne-prone skin?
HydroPeptide Power Serum is a great fit because ingredients like Barosma Betulina Leaf Extract and Hexapeptide-11 help control excess oil and breakouts, while Tetrahexyldecyl Ascorbate brightens and smooths your skin. Tocopherol and Glycerin also help keep the formula gentle and unlikely to cause irritation.
Which ingredients make this serum a good fit for oily acne-prone skin?
Barosma Betulina Leaf Extract and Hexapeptide-11 help regulate oil and condition oily skin, while Tetrahexyldecyl Ascorbate brightens skin tone and smooths texture. Tocopherol and Glycerin also help keep the formula gentle and minimize irritation.
What does Palmitoyl Tripeptide-5 do for oily acne-prone skin?
Palmitoyl tripeptide-5 helps smooth fine lines and firms the skin, though it is not a direct treatment for oily or acne-prone skin. This type of skin needs ingredients that help control excess oil, clear pores, and calm breakouts.
What does Hexapeptide-11 do for oily acne-prone skin?
Hexapeptide-11 helps protect skin cells from everyday damage and may improve firmness, but oily acne-prone skin also needs ingredients that control oil and soothe swelling to truly stay clear and smooth.
Where does this serum go in a skincare routine for oily acne-prone skin?
This serum goes in the evening routine after cleansing and before moisturizing, though some can also be used in the morning or twice a day. Applying treatments in the evening helps keep things simple and provides extra safety around sun exposure.
Can I use this serum with retinol, and in what order?
You can use this treatment alongside retinol by applying the retinol first at night, followed by this serum in your routine. This helps manage breakouts while keeping your skin calm, as the gentle ingredients minimize irritation.
Journal of Cosmetic Dermatology, 2024American Family Physician, 2012
How often should I use this serum?
You can use this serum in your evening routine, and some treatments like this one may also be used in the morning or twice a day. Its gentle ingredients are unlikely to cause irritation while helping to balance oil and brighten your skin.
Can this serum clog pores, cause breakouts or purging for oily acne-prone skin?
This serum is a great fit for your oily acne-prone skin, as it uses ingredients that help control oil and condition the skin without clogging pores. It also includes gentle ingredients that minimize the likelihood of irritation or breakouts.
Is this serum fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol. Cetearyl alcohol is a fatty alcohol, which soften the skin.
What the research says
A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers.
Journal of Cosmetic Dermatology, 2020Hyaluronic acid extracts are safe and efficacious products for skin repair when used in tissue regeneration alone or in combination with herbal or Western medicine.
Journal of Pharmacy & Pharmaceutical Sciences, 2015Supramolecular collagen nanoparticles composed of lactoferrin, recombinant human collagen, and palmitoyl tripeptide-5 improved transdermal efficiency by 69.90% and demonstrated moisturizing, whitening, wrinkle reduction, and firming effects.
Colloids and Surfaces. B, Biointerfaces, 2025Hexapeptide-11 activated proteasome, autophagy, chaperones, and antioxidant response genes, protected fibroblasts against oxidative-stress-mediated premature cellular senescence, and improved skin elasticity in human subjects.
Redox Biology, 2015Hexapeptide-11 reversibly downregulated ATM and p53 protein expression in intrinsically aged fibroblasts, extrinsically aged fibroblasts, and extrinsically aged dermal papillae cells at concentrations between 0.1% and 1.0% in vitro, thereby influencing the onset of cellular senescence.
Journal of Cosmetic Science, 2013Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019
Ingredients
Water, Glycerin, Lactococcus Lysate Ferment, Butylene Glycol, Propanediol, Diethylhexyl Carbonate, Isopentyldiol, Pentylene Glycol, Diheptyl Succinate, Caprylyl Glycol, Hydroxyacetophenone, Olea Europaea Fruit Olive Fruit, Sodium Stearoyl Glutamate, Cetearyl Alcohol, Glyceryl Stearate, Potassium Olivoyl Hydrolyzed Oat Protein, Lysolecithin, Sclerotium Gum, Hexapeptide-11, Tetrahexyldecyl Ascorbate, 1,2-Hexanediol, Capryloyl Glycerin Sebacic Acid Copolymer, Phenylpropanol, Sorbitan Laurate, Pullulan, Xanthan Gum, Caprylic Capric Triglyceride, Glyceryl Oleate, Glycine Soja Seed Extract Soybean Seed Extract, Anogeissus Leiocarpus Bark Extract, Lemon Peel Extract, Palmitoyl Hexapeptide-19, Sodium Phytate, Hydroxyethylcellulose, Sodium Hyaluronate, Acetyl Dipeptide-1 Cetyl Ester, Citrus Aurantium Dulcis Peel Extract, Grapefruit Fruit Extract, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Bergamot Fruit Extract, Citrus Aurantifolia Peel Extract, Citrus Nobilis Fruit Extract Mandarin Orange Fruit Extract, Tangerine Peel Extract, Acetyl Hexapeptide-30, Barosma Betulina Leaf Extract, Vanilla Planifolia Fruit Extract, Vitis Vinifera Fruit Extract Grape Fruit Extract, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Palmitoyl Tripeptide-5, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Tocopherol
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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