# Estée Lauder Futurist Peptide-Power Serum Primer for acne-prone skin

**Lovi Fit: Average fit for acne-prone skin.**
Combination Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/ae/p/estee-lauder/futurist-peptide-power-serum-primer/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Arab Emirates.

Brand: [Estée Lauder](https://lovi.care/skincare/ae/brands/estee-lauder)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/ae/best/moisturizers)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for acne-prone skin; other moisturizers fit it better.

## Why this fit

- Offers excellent moisturizing and treatment for your combination skin due to the presence of Glycerin and Sodium Hyaluronate, which hydrate drier areas without exacerbating oiliness.
- Provides moderate benefits for acne, blemishes, and breakouts with peptides like Acetyl Hexapeptide-8 and Palmitoyl Hexapeptide-12 supporting skin repair, though targeted acne treatment ingredients are lacking.
- The safety profile is excellent, with no risks of irritation for your combination skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ae/p/estee-lauder/futurist-peptide-power-serum-primer/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ae/p/estee-lauder/futurist-peptide-power-serum-primer/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/ae/p/estee-lauder/futurist-peptide-power-serum-primer/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/ae/p/estee-lauder/futurist-peptide-power-serum-primer/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/ae/p/estee-lauder/futurist-peptide-power-serum-primer/for/acne-prone-skin): Average (this page)
- [Skin with dark spots](https://lovi.care/skincare/ae/p/estee-lauder/futurist-peptide-power-serum-primer/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/ae/p/estee-lauder/futurist-peptide-power-serum-primer/for/mature-skin): Superior
- [Dry sensitive skin](https://lovi.care/skincare/ae/p/estee-lauder/futurist-peptide-power-serum-primer/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/ae/p/estee-lauder/futurist-peptide-power-serum-primer/for/oily-acne-prone-skin): Average

## Key ingredients

Acetyl Hexapeptide-8, Palmitoyl Hexapeptide-12, Sodium Hyaluronate, Glycerin, Tetrahexyldecyl Ascorbate

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Palmitoyl hexapeptide-12 permeates the stratum corneum and epidermis, initiating gel formation via endogenous ions and strengthening and repairing the skin barrier after delipidation in human skin. ([ACS Applied Bio Materials, 2025](https://pubmed.ncbi.nlm.nih.gov/39964201/))
- A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo. ([Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/))
- Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days. ([Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/))
- Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group. ([American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/))
- Acetyl hexapeptide-3 and tripeptide-10 citrulline demonstrated antiwrinkle efficacy and decreased transepidermal water loss in twenty-four healthy volunteers compared to control groups, though synergistic effects between the two peptides remained unclear. ([Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28150423/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))

## Why other moisturizers fit acne-prone skin better

- A peel-off facial mask containing myoinositol and trehalose-loaded liposomes improved adult female acne by decreasing lesion counts, sebum production, GAGS scores, and local androgen levels while increasing beclin-1 levels. ([Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28342238/))
- A Tris/Arg-formulated cleanser significantly decreased noninflammatory and inflammatory acne and pore size with keratotic plugs compared to an AEC/AC cleanser in male Thai subjects with mild to moderate acne over 4 weeks. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31347768/))

## What reviewers say

This serum-gel primer is highly praised for its hydrating, plumping, and smoothing effects, making it an excellent choice for mature skin or those seeking a radiant, dewy finish. While it excels at creating a smooth, makeup-ready canvas, some users find the packaging frustrating and the price point high for the amount of product provided.

- Liked: Intense hydration (often mentioned)
- Liked: Radiant finish (often mentioned)
- Liked: Makeup-gripping base (sometimes noted)
- Liked: Smooths fine lines (sometimes noted)
- Disliked: High price/value (sometimes noted)
- Disliked: Poor packaging (sometimes noted)
- Disliked: Heavy/comedogenic concerns (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help keep breakouts under control.
- Apply after your cleanser and toner, and make sure to use your SPF right after in the morning.
- Gently spread a small amount of moisturizer over your face using soft motions. Let it absorb into the skin for a minute before getting dressed or applying makeup.
- Apply on slightly damp skin to help lock in extra moisture. This keeps your combination skin balanced without feeling heavy.
- Avoid the eye area and do a patch test before your first use. Stop using if you feel any irritation.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Estée Lauder Futurist Peptide-Power Serum Primer work for acne-prone skin?

This product works decently for acne-prone skin, providing moderate benefits through peptides that support skin repair, though it lacks targeted acne-fighting ingredients. To work even better for this skin type, a product needs effective ingredients like niacinamide and hyaluronic acid to provide great hydration and texture improvement without triggering breakouts.
Sources: [ACS Applied Bio Materials, 2025](https://pubmed.ncbi.nlm.nih.gov/39964201/), [Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/)

### Which ingredients make this serum a good fit for acne-prone skin?

This serum works for acne-prone skin because it contains glycerin and sodium hyaluronate to keep dry areas soft without adding extra oil, along with peptides like acetyl hexapeptide-8 and palmitoyl hexapeptide-12 that help repair the skin. Because it lacks targeted blemish-fighting ingredients, a product of this type needs effective ingredients like niacinamide and hyaluronic acid to provide better hydration and texture improvement while keeping oil balanced.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [ACS Applied Bio Materials, 2025](https://pubmed.ncbi.nlm.nih.gov/39964201/)

### What does Argireline do for acne-prone skin?

Argireline is not typically targeted for acne-prone skin, as it is primarily used to smooth fine lines and reduce wrinkles by relaxing facial movements. While it helps keep skin smooth, acne-prone skin generally needs ingredients that clear pores, calm redness, and balance oil production.

### What does Palmitoyl Hexapeptide-12 do for acne-prone skin?

Palmitoyl hexapeptide-12 helps strengthen and repair the skin barrier, making it a supportive option for acne-prone skin that is recovering from dryness or irritation. This ingredient works by sinking into the outer skin layers to help restore skin health, which is unlikely to cause clogging or breakouts.
Sources: [ACS Applied Bio Materials, 2025](https://pubmed.ncbi.nlm.nih.gov/39964201/)

### Where does this serum go in a skincare routine for acne-prone skin?

This treatment goes in the evening routine after cleansing and before moisturizing, though it is an average fit for acne-prone skin. To work best for blemishes and breakouts, this skin type needs targeted blemish-fighting ingredients alongside hydrating and repairing components.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first to keep your skin smooth and hydrated while preparing it for retinol, as barrier-enhancing moisturizers help reduce irritation. This product works well for your skin, though acne-prone skin needs products containing targeted blemish-fighting ingredients and barrier-repairing ceramides.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this serum?

This serum works well as an evening treatment, though you can also use it in the morning or twice a day if your skin tolerates it. Daily use helps keep your skin soft and smooth while supporting repair, but this skin type also needs targeted blemish-fighting ingredients for the best fit.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this serum clog pores, cause breakouts or purging for acne-prone skin?

This serum is unlikely to cause breakouts or clog pores because it has an excellent safety profile with no harsh ingredients, though acne-prone skin still needs targeted acne-fighting ingredients for the best care.

### Can I use this serum around the eyes or on my body?

You can use this serum around the eyes, where the skin is very thin and benefits from gentle hydrating ingredients like glycerin and sodium hyaluronate. A product of this type needs soothing hydrators and barrier-repairing peptides to safely care for delicate areas without causing irritation.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for acne-prone skin

- [Revision Skincare Hydrating Serum](https://lovi.care/skincare/ae/p/revision-skincare/hydrating-serum/for/acne-prone-skin) — Superior fit — AED 333.85 at Amazon
- [Elizavecca Witch Piggy Hell Pore Control Hyaluronic Acid 97%](https://lovi.care/skincare/ae/p/elizavecca/witch-piggy-hell-pore-control-hyaluronic-acid-97/for/acne-prone-skin) — Superior fit — AED 53.01 at Amazon
- [innisfree Green Tea Seed Hyaluronic Acid Hydrating Serum](https://lovi.care/skincare/ae/p/innisfree/green-tea-seed-hyaluronic-acid-hydrating-serum/for/acne-prone-skin) — High fit — AED 92.81 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/ae/p/cerave/foaming-facial-cleanser/for/acne-prone-skin) — Superior fit — AED 49.95 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/ae/p/some-by-mi/snail-truecica-miracle-repair-toner/for/acne-prone-skin) — Superior fit — AED 49.99 at Amazon
- SPF: [d'Alba Piedmont Waterfull Mild Sunscreen](https://lovi.care/skincare/ae/p/d-alba/piedmont-waterfull-mild-sunscreen/for/acne-prone-skin) — Superior fit — AED 92.70 at Amazon

## Where to buy

No store in United Arab Emirates has a checked price for this product, so the page shows none.

## Ingredients

Water, Butylene Glycol, Glycerin, Acetyl Hexapeptide-8, Palmitoyl Hexapeptide-12, Sodium Pca, Whey Lactis Proteine Du Petit-Lait Protein, Glycine Soja Protein Soybean Protein, Sodium Hyaluronate, Acetyl Glucosamine, Lactobacillus Ferment, Tetrahexyldecyl Ascorbate, Chlorella Vulgaris Extract, Algae Extract, Caprylyl Glycol, Caffeine, Hydrolyzed Rice Extract, Laminaria Digitata Extract, Glucose, Artemia Extract, Sucrose, Peg-8, Xanthan Gum, Sodium Polyacryloyldimethyl Taurate, Calcium Chloride, Glyceryl Polymethacrylate, Sodium Hydroxide, Propanediol, Bht, Tocopheryl Acetate, Disodium Edta, Silica, Phenoxyethanol, Potassium Sorbate, Chlorphenesin, Mica, Titanium Dioxide Ci 77891, Iron Oxides Ci 77492, Bismuth Oxychloride, Carmine
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/estee-lauder/futurist-peptide-power-serum-primer/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/estee-lauder/futurist-peptide-power-serum-primer/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/estee-lauder/futurist-peptide-power-serum-primer/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/estee-lauder/futurist-peptide-power-serum-primer/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/estee-lauder/futurist-peptide-power-serum-primer/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/estee-lauder/futurist-peptide-power-serum-primer/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/estee-lauder/futurist-peptide-power-serum-primer/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/estee-lauder/futurist-peptide-power-serum-primer/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/estee-lauder/futurist-peptide-power-serum-primer/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/estee-lauder/futurist-peptide-power-serum-primer/for/acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/estee-lauder/futurist-peptide-power-serum-primer/for/acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/estee-lauder/futurist-peptide-power-serum-primer/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/estee-lauder/futurist-peptide-power-serum-primer/for/acne-prone-skin (this page)