# Dr. Lili Fan Probiotic Age Defying Eye Serum for combination skin

**Lovi Fit: Average fit for combination skin.**
Combination Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/ae/p/dr-lili-fan/probiotic-age-defying-eye-serum/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Arab Emirates.

Brand: [Dr. Lili Fan](https://lovi.care/skincare/ae/brands/dr-lili-fan)
Category: [Eye care and eye patches](https://lovi.care/skincare/ae/best/eye-creams)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for combination skin; other eye cares fit it better.

## Why this fit

- Offers moderate plumping and firming for your combination skin due to peptides like Myristoyl Pentapeptide-17 and Palmitoyl Oligopeptide, which support skin elasticity. Sodium Hyaluronate and Glycerin provide essential hydration, while Lactobacillus Ulkenia Extract Ferment Filtrate and Bifida Lysate Ferment help repair your skin barrier.
- While beneficial for general hydration and barrier support, the formula does not specifically target your oily shine concerns.
- The product is safe for your combination skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ae/p/dr-lili-fan/probiotic-age-defying-eye-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ae/p/dr-lili-fan/probiotic-age-defying-eye-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/ae/p/dr-lili-fan/probiotic-age-defying-eye-serum/for/combination-skin): Average (this page)
- [Sensitive skin](https://lovi.care/skincare/ae/p/dr-lili-fan/probiotic-age-defying-eye-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/ae/p/dr-lili-fan/probiotic-age-defying-eye-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/ae/p/dr-lili-fan/probiotic-age-defying-eye-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ae/p/dr-lili-fan/probiotic-age-defying-eye-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/ae/p/dr-lili-fan/probiotic-age-defying-eye-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/ae/p/dr-lili-fan/probiotic-age-defying-eye-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Sodium Hyaluronate, Myristoyl Pentapeptide-17, Palmitoyl Tetrapeptide-7, Lactobacillus Ulkenia Extract Ferment Filtrate, Bifida Lysate Ferment

## What the research says

- A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo. ([Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/))
- Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants. ([Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical application of Bifida Ferment Lysate strengthens the skin barrier function by upregulating barrier and antimicrobial peptide genes, exhibiting strong antioxidant properties, and decreasing inflammatory cytokine secretion in vitro. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37218728/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Palmitoyl tetrapeptide-7, acetyl hexapeptide-8, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-10 significantly increased type III collagen levels in human dermal fibroblasts following UV exposure, with their combination demonstrating a greater effect in vitro and enhancing type I, III, and IV collagen levels in ex vivo skin tissues compared to individual components. ([International Journal of Cosmetic Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42683869/))

## Why other eye cares fit combination skin better

- Combined ascorbyl palmitate and sodium ascorbyl phosphate treatment significantly reduced facial sebum secretions in healthy female volunteers compared to a placebo control over 90 days. ([Drug Research, 2017](https://pubmed.ncbi.nlm.nih.gov/27756097/))
- Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo. ([BioMed Research International, 2022](https://pubmed.ncbi.nlm.nih.gov/35342760/))

## Questions and answers

### How well does Dr. Lili Fan Probiotic Age Defying Eye Serum work for combination skin?

This eye serum works well enough for combination skin by delivering moderate hydration and firming, though it does not target oily shine concerns. An eye product for this skin needs lightweight hydrators and balancing ingredients that smooth the eye area without feeling heavy.
Sources: [Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for combination skin?

This serum works well for combination skin because it includes sodium hyaluronate and glycerin for essential moisture, along with peptides like myristoyl pentapeptide-17 and palmitoyl tetrapeptide-7 that help keep the skin firm and smooth. Probiotic ferments such as lactobacillus and bifida lysate also help calm and repair the skin barrier. To be a top fit for this skin type, a product of this type needs lightweight hydrators, barrier-repairing ferments, and gentle balancing ingredients that manage oily shine without heavy oils.
Sources: [Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Hyaluronic Acid do for combination skin?

Hyaluronic acid is a great fit for combination skin because it quenches dry areas with a boost of hydration while keeping oily zones balanced. Regular use helps smooth out fine lines and makes your skin feel soft and plump without causing irritation.
Sources: [Dermatology and Therapy, 2021](https://pubmed.ncbi.nlm.nih.gov/34176098/), [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/)

### What does Myristoyl Pentapeptide-17 do for combination skin?

Myristoyl Pentapeptide-17 helps support skin renewal and encourages a healthy, smooth look for combination skin. This ingredient works by supporting the proteins that keep skin feeling firm and resilient. To get the best results on combination skin, this type of product needs to be paired with lightweight hydrators that balance dry and oily areas without clogging pores.
Sources: [Tissue Engineering. Part A, 2009](https://pubmed.ncbi.nlm.nih.gov/19292667/)

### Where does it go in a skincare routine for combination skin?

This eye serum goes in the evening routine as a treatment after cleansing and before moisturizing. Because it contains peptides like palmitoyl oligopeptide and palmitoyl tetrapeptide-7, it may help improve firmness and elasticity.
Sources: [Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/), [Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/)

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol, applying the serum first to give your skin hydration and barrier support before your retinol treatment. This product is safe for your combination skin, though an eye serum for this skin type also needs ingredients that balance oily shine.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use it?

You can use this eye serum daily, morning and night, as part of your regular routine. It is safe for your skin and unlikely to cause irritation, providing helpful hydration and barrier support.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can this serum clog pores, cause breakouts or purging for combination skin?

This serum is unlikely to clog pores or cause breakouts on your combination skin because it lacks heavy or harsh ingredients that typically trigger irritation. To better manage oily shine alongside hydration, combination skin needs lightweight formulas with oil-balancing or mattifying ingredients.

### Is it fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for combination skin

- [MARY & MAY Tranexamic Acid + Glutathione Eye Cream](https://lovi.care/skincare/ae/p/mary-and-may/tranexamic-acid-glutathione-eye-cream/for/combination-skin) — High fit — AED 13.23 at Amazon
- [Lancome Advanced Genifique Yeux Light-Pearl Eye & Lash Concentrate](https://lovi.care/skincare/ae/p/lancome/advanced-genifique-yeux-light-pearl/for/combination-skin) — High fit — AED 400.00 at Amazon
- [Valmont Serum Majestueux Vos Yeux](https://lovi.care/skincare/ae/p/valmont/serum-majestueux-vos-yeux/for/combination-skin) — Average fit — AED 1,708.95 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ae/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — AED 84.53 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/ae/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — AED 145.00 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/ae/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — AED 33.40 at Amazon

## Where to buy

No store in United Arab Emirates has a checked price for this product, so the page shows none.

## Ingredients

Water, Sodium Hyaluronate, Menthyl Lactate, Asiatic Acid, Pentylene Glycol, Panthenol, Steareth-20, Glycerin, Lysolecithin, N-Hydroxysuccinimide, Hydroxyethylcellulose, Chrysin, Myristoyl Pentapeptide-17, Cocoyl-Oligopeptide, Palmitoyl Oligopeptide, Palmitoyl Tetrapeptide-7, Rice Protein, Lactobacillus Ulkenia Extract Ferment Filtrate, Bifida Lysate Ferment, Phenoxyethanol, Caprylyl Glycol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/dr-lili-fan/probiotic-age-defying-eye-serum/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/dr-lili-fan/probiotic-age-defying-eye-serum/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/dr-lili-fan/probiotic-age-defying-eye-serum/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/dr-lili-fan/probiotic-age-defying-eye-serum/for/combination-skin
- France: https://lovi.care/skincare/fr/p/dr-lili-fan/probiotic-age-defying-eye-serum/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/dr-lili-fan/probiotic-age-defying-eye-serum/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/dr-lili-fan/probiotic-age-defying-eye-serum/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/dr-lili-fan/probiotic-age-defying-eye-serum/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/dr-lili-fan/probiotic-age-defying-eye-serum/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/dr-lili-fan/probiotic-age-defying-eye-serum/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/dr-lili-fan/probiotic-age-defying-eye-serum/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/dr-lili-fan/probiotic-age-defying-eye-serum/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/dr-lili-fan/probiotic-age-defying-eye-serum/for/combination-skin (this page)