# Dewytree Miracle Clear Serum for acne-prone skin

**Lovi Fit: High fit for acne-prone skin.**
Combination Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/ae/p/dewytree/miracle-clear-serum/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Arab Emirates.

Brand: [Dewytree](https://lovi.care/skincare/ae/brands/dewytree)
Category: [Serums and treatments](https://lovi.care/skincare/ae/best/serums)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for acne-prone skin; a few serums fit it even better.

## Why this fit

- Offers excellent treatment for your acne-prone skin, as papain exfoliates blemishes and Centella Asiatica Extract calms irritation, while Squalane and Glycerin balance your combination skin without exacerbating oiliness.
- The presence of Madecassoside and Asiaticoside further aids in skin repair and provides moderate benefits for your breakouts.
- The formula is safe for your skin, with no risks of irritation due to the absence of harsh ingredients and the inclusion of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ae/p/dewytree/miracle-clear-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/ae/p/dewytree/miracle-clear-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/ae/p/dewytree/miracle-clear-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/ae/p/dewytree/miracle-clear-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/ae/p/dewytree/miracle-clear-serum/for/acne-prone-skin): High (this page)
- [Skin with dark spots](https://lovi.care/skincare/ae/p/dewytree/miracle-clear-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ae/p/dewytree/miracle-clear-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/ae/p/dewytree/miracle-clear-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/ae/p/dewytree/miracle-clear-serum/for/oily-acne-prone-skin): High

## Key ingredients

Centella Asiatica Extract, Sodium Hyaluronate, Madecassoside, Squalane, Glycerin

## What the research says

- A fixed combination of hydroxypinacolone retinoate, retinol glycospheres, and papain glycospheres in aqueous gel applied once daily for 12 weeks achieved a 41% mean reduction in GAGS score and a 40.8% mean reduction in total lesions, with 15.3% of patients experiencing mild to moderate local side effects, in 94 evaluable patients with comedonal-papular, mild to moderate acne of the face. ([Giornale Italiano Di Dermatologia E Venereologia, 2015](https://pubmed.ncbi.nlm.nih.gov/25876142/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- The novel high-payload nanosuspension system of Centella asiatica extract increased skin accumulation of asiatic acid, madecassic acid, and asiaticoside by 5-, 4-, and 4.5-fold respectively compared to a marketed cream in porcine skin, with no local skin irritation in normal rats. ([International Journal of Nanomedicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34764648/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))

## What reviewers say

Based on limited data, users with sensitive, acne-prone, and combination skin find this serum's lightweight, layerable texture beneficial for soothing redness and calming blemishes over time. Many appreciate its hydrating effect, though a notable number find the dropper packaging difficult to use and note that results can be subtle rather than dramatic.

- Disliked: Difficult dropper packaging (mostly mentioned)
- Liked: Lightweight texture (often mentioned)
- Liked: Soothes redness (often mentioned)
- Liked: Good value (sometimes noted)
- Liked: Hydrating feel (sometimes noted)
- Disliked: Subtle or slow results (sometimes noted)
- Disliked: Small quantity (rarely noted)
- Disliked: Unpleasant scent (rarely noted)

## How to apply

- Use your serum as part of your PM routine and start 3x/week before working up to daily use.
- Apply this treatment after cleansing and toner, and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the product on clean, dry skin to help manage your breakouts safely.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Dewytree Miracle Clear Serum a great fit for acne-prone skin?

This serum is a great fit because papain exfoliates blemishes and Centella Asiatica extract calms irritation, while squalane and glycerin balance your skin without adding extra oil. Ingredients like madecassoside also help repair your skin and provide moderate benefits for breakouts. The formula is very safe and is unlikely to cause irritation.
Sources: [Giornale Italiano Di Dermatologia E Venereologia, 2015](https://pubmed.ncbi.nlm.nih.gov/25876142/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### Which ingredients make this serum a good fit for acne-prone skin?

Papain exfoliates blemishes and Centella Asiatica Extract calms irritation, while Squalane and Glycerin balance your skin without adding oil. Madecassoside and Asiaticoside further help repair your skin and provide moderate benefits for breakouts.
Sources: [Giornale Italiano Di Dermatologia E Venereologia, 2015](https://pubmed.ncbi.nlm.nih.gov/25876142/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### What does Centella Asiatica Extract do for acne-prone skin?

Centella asiatica extract helps calm angry skin, reduces redness, and supports healing for breakouts. It is unlikely to cause irritation and may improve overall skin clarity when used consistently.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/)

### What does Hyaluronic Acid do for acne-prone skin?

Hyaluronic acid helps acne-prone skin by soothing irritation, calming redness, and keeping the skin balanced without clogging pores. When combined with targeted ingredients like zinc oxide, it may also help reduce breakouts.
Sources: [Biomedicines, 2025](https://pubmed.ncbi.nlm.nih.gov/41007718/), [Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/)

### Where does it go in a skincare routine for acne-prone skin?

This treatment goes in the evening routine after cleansing and before moisturizing, for simplicity and extra safety around sun exposure. It is unlikely to cause irritation because it lacks harsh ingredients and includes soothing components.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first to calm and hydrate your skin, followed by your retinol. This pairing helps balance your skin while keeping the risk of irritation low.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### How often should I use it?

You can use this treatment in your evening routine, applying it once a day or a few times a week. It is safe for your skin, with no risks of irritation due to the absence of harsh ingredients and the inclusion of soothing components.
Sources: [Giornale Italiano Di Dermatologia E Venereologia, 2015](https://pubmed.ncbi.nlm.nih.gov/25876142/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### Can this serum clog pores, cause breakouts or purging for acne-prone skin?

This serum is unlikely to clog pores or cause breakouts for acne-prone skin because it contains soothing ingredients that calm irritation and balance skin without adding extra oiliness. The formula is generally safe for your skin with no risks of harsh irritation.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [International Journal of Nanomedicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34764648/)

### Is it fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for acne-prone skin

- [Clinique Fresh Pressed Daily Booster with Pure Vitamin C 10%](https://lovi.care/skincare/ae/p/clinique/fresh-pressed-daily-booster-with-pure-vitamin-c-10/for/acne-prone-skin) — Superior fit — AED 365.22 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/ae/p/skinceuticals/c-e-ferulic/for/acne-prone-skin) — Superior fit — AED 715.99 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/ae/p/neogen-dermalogy/real-vitamin-c-serum/for/acne-prone-skin) — Superior fit — AED 89.30 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/ae/p/cerave/foaming-facial-cleanser/for/acne-prone-skin) — Superior fit — AED 49.95 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/ae/p/some-by-mi/snail-truecica-miracle-repair-toner/for/acne-prone-skin) — Superior fit — AED 49.99 at Amazon
- Moisturizer: [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/ae/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/acne-prone-skin) — Superior fit — AED 91.81 at Amazon

## Where to buy

- Amazon.ae: AED 74.78 (https://www.amazon.ae/dp/B0BVM8S565?tag=lovi00-21&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, Butylene Glycol, Propanediol, Glycerin, Squalane, Cetearyl Alcohol, Macadamia Ternifolia Seed Oil, Limnanthes Alba Seed Oil, Helianthus Annuus Seed Oil Sunflower Seed Oil, Menadione, Sodium Hyaluronate, Centella Asiatica Extract, Madecassoside, Asiaticoside, Madecassic Acid, Hydrogenated Lecithin, Polysorbate 60, Sorbitan Isostearate, Caprylic Capric Triglyceride, Dimethicone, Hydroxyethylcellulose, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Carbomer, Xanthan Gum, Arginine, 1,2-Hexanediol, Chlorphenesin, Caprylyl Glycol, Cholesterol, Brassica Campestris Sterols, Allantoin, Dipotassium Glycyrrhizate, Panthenol, Papain, Disodium Edta
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/dewytree/miracle-clear-serum/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/dewytree/miracle-clear-serum/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/dewytree/miracle-clear-serum/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/dewytree/miracle-clear-serum/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/dewytree/miracle-clear-serum/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/dewytree/miracle-clear-serum/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/dewytree/miracle-clear-serum/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/dewytree/miracle-clear-serum/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/dewytree/miracle-clear-serum/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/dewytree/miracle-clear-serum/for/acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/dewytree/miracle-clear-serum/for/acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/dewytree/miracle-clear-serum/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/dewytree/miracle-clear-serum/for/acne-prone-skin (this page)