# Derma E Retinol Concentrated Serum for acne-prone skin

**Lovi Fit: High fit for acne-prone skin.**
Combination Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/ae/p/derma-e/retinol-concentrated-serum/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Arab Emirates.

Brand: [Derma E](https://lovi.care/skincare/ae/brands/derma-e)
Category: [Serums and treatments](https://lovi.care/skincare/ae/best/serums)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for acne-prone skin; a few serums fit it even better.

## Why this fit

- Offers excellent wrinkle reduction and acne control for your combination skin, as retinol and bakuchiol promote skin renewal and reduce inflammation. Glycerin and allantoin provide soothing benefits, ensuring comfort for acne-prone skin.
- Astaxanthin and sodium hyaluronate further enhance skin hydration and offer antioxidant protection, supporting overall skin health.
- The product is safe for your skin, with no risks of irritation due to the absence of harsh ingredients and the inclusion of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ae/p/derma-e/retinol-concentrated-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ae/p/derma-e/retinol-concentrated-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/ae/p/derma-e/retinol-concentrated-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/ae/p/derma-e/retinol-concentrated-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/ae/p/derma-e/retinol-concentrated-serum/for/acne-prone-skin): High (this page)
- [Skin with dark spots](https://lovi.care/skincare/ae/p/derma-e/retinol-concentrated-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/ae/p/derma-e/retinol-concentrated-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/ae/p/derma-e/retinol-concentrated-serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/ae/p/derma-e/retinol-concentrated-serum/for/oily-acne-prone-skin): High

## Key ingredients

Encapsulated Retinol, Bakuchiol, Punica Granatum Extract, Astaxanthin, Sodium Hyaluronate

## What the research says

- Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging. ([The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/))
- Combining oral and topical astaxanthin in 30 healthy females improved skin wrinkles, age spots, elasticity, texture, and moisture, while 6 mg daily oral supplementation in 36 healthy males improved crow's feet wrinkles, elasticity, and transepidermal water loss. ([Acta Biochimica Polonica, 2012](https://pubmed.ncbi.nlm.nih.gov/22428137/))
- Astaxanthin-loaded polyhydroxybutyrate microbeads achieved 98.1% encapsulation efficiency with sustained release, reduced degradation by 2-fold compared to unencapsulated astaxanthin, and showed no cytotoxicity or skin irritation in human cells and tests. ([International Journal of Biological Macromolecules, 2024](https://pubmed.ncbi.nlm.nih.gov/38072340/))
- Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle. ([International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/))
- Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity. ([Journal of Controlled Release, 2018](https://pubmed.ncbi.nlm.nih.gov/29604311/))
- Topical stabilized retinol treatment induced HAS gene expression and increased hyaluronic acid production in human skin in vitro, ex vivo, and in vivo compared to vehicle. ([Archives of Dermatological Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28247017/))
- A dermocosmetic containing bakuchiol, Ginkgo biloba extract, and mannitol improves inflammatory lesions, Investigator Global Assessment, and seborrhea intensity when added to adapalene 0.1% gel in patients with acne vulgaris. ([Clinical, Cosmetic and Investigational Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25914553/))
- Topical application of a serum containing supramolecular Bakuchiol and Terminalia chebula extract significantly improved barrier function, reduced redness and sensitivity, and improved wrinkles and elasticity in 34 Chinese subjects with sensitive skin after 28 days. ([Health Science Reports, 2025](https://pubmed.ncbi.nlm.nih.gov/41424674/))
- Bakuchiol functions as an anti-aging compound through retinol-like regulation of gene expression, producing significant improvements in lines, wrinkles, pigmentation, elasticity, firmness, and photo-damage after 12 weeks of twice-a-day facial application without usual retinol therapy-associated undesirable effects. ([International Journal of Cosmetic Science, 2014](https://pubmed.ncbi.nlm.nih.gov/24471735/))
- Phenolic-rich pomegranate peel extract formulated into a serum and mask showed significantly better facial skin lightening efficacy than placebo in 30 volunteers over 28 days. ([Planta Medica, 2020](https://pubmed.ncbi.nlm.nih.gov/32428937/))
- Topical application of a 2% cream containing combined fruit extracts for 56 days significantly reduced wrinkle depth by 11.5%, length by 10.07%, and area by 29.55% in 21 female subjects compared to a placebo. ([Clinical, Cosmetic and Investigational Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/26203268/))
- A topical microemulsion containing Punica granatum extract significantly reduced skin erythema and melanin compared to a placebo in healthy Asian subjects over 12 weeks. ([Postepy Dermatologii I Alergologii, 2014](https://pubmed.ncbi.nlm.nih.gov/25610348/))
- Oral astaxanthin supplementation significantly restored moisture content and improved elasticity but did not significantly decrease wrinkle depth compared to placebo in humans. ([Nutrients, 2021](https://pubmed.ncbi.nlm.nih.gov/34578794/))
- Twice-daily application of a novel topical antioxidant formulation safe, well-tolerated, and effective in improving overall skin quality, fine lines, wrinkles, radiance, and hyperpigmentation in 32 healthy female subjects over 12 weeks. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37608511/))
- Astaxanthin prevents UV-induced cutaneous inflammation, abnormal keratinization, wrinkling, and pigmentation in human skin even when applied postirradiation. ([Photochemistry and Photobiology, 2019](https://pubmed.ncbi.nlm.nih.gov/30338860/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))

## What reviewers say

Based on a very large amount of data, this serum is frequently praised for being gentle and suitable for sensitive skin, effectively improving texture and firmness. Many users report positive results without irritation, making it a good option for those new to retinol. Some users express frustration with the dropper design, and a few mention slow results or a sticky texture.

- Liked: Gentle on skin (mostly mentioned)
- Liked: Improves texture (often mentioned)
- Liked: Absorbs quickly (sometimes noted)
- Liked: Good for beginners (sometimes noted)
- Disliked: Dropper design issues (sometimes noted)
- Disliked: Slow results (rarely noted)
- Disliked: Sticky texture (rarely noted)

## How to apply

- Use your serum as part of your PM routine and start 3x/week before working up to daily use.
- Apply this treatment after cleansing and toner, and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the product on clean, dry skin to help manage your breakouts safely.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes DERMA E Retinol Serum a great fit for acne-prone skin?

DERMA E Retinol Concentrated Serum is a great fit because retinol and bakuchiol promote skin renewal and reduce inflammation, while glycerin and allantoin provide soothing comfort for acne-prone skin. Astaxanthin and sodium hyaluronate further enhance skin hydration and offer antioxidant protection.
Sources: [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/)

### Which ingredients make this serum a good fit for acne-prone skin?

Encapsulated retinol and bakuchiol make this serum a great fit by promoting skin renewal and reducing inflammation to help control breakouts. Soothing ingredients like glycerin and allantoin provide extra comfort, keeping acne-prone skin calm and balanced.
Sources: [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/)

### What does Encapsulated Retinol do for acne-prone skin?

Encapsulated retinol helps clear acne-prone skin by reducing pimples and dark spots while keeping irritation low. This ingredient is generally well tolerated, helping to smooth skin texture and improve overall clarity over time.
Sources: [Giornale Italiano Di Dermatologia E Venereologia, 2020](https://pubmed.ncbi.nlm.nih.gov/32869963/)

### What does Bakuchiol do for acne-prone skin?

Bakuchiol helps clear acne-prone skin by reducing pimples and dark spots without the stinging and scaling often caused by stronger treatments. It works well to calm redness and is unlikely to irritate sensitive skin.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25914553/), [Journal of Drugs in Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33683079/)

### Where does this serum go in a skincare routine for acne-prone skin?

This serum goes in your evening routine, keeping your skin safe from extra sun exposure while helping to clear acne and smooth wrinkles. It is applied after cleansing and toning, and right before your moisturizer.

### Can I use this serum with vitamin C, and in what order?

It is best to use vitamin C in your morning routine and this retinol serum at night to help prevent irritation on acne-prone skin. Applying them at different times of day lets both ingredients work effectively while keeping your skin calm and smooth.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/), [American Family Physician, 2012](https://pubmed.ncbi.nlm.nih.gov/23062156/)

### How often should I use this serum?

You can use this treatment in your evening routine, applying it once a week at first and carefully working up to more often if your skin tolerates it well. This routine helps your skin renew itself while reducing acne and wrinkles, with soothing ingredients included to keep your skin comfortable and calm.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38406974/), [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/)

### Can this serum clog pores, cause breakouts or purging for acne-prone skin?

This serum is a great fit for acne-prone skin because retinol and bakuchiol promote skin renewal and reduce inflammation, while soothing ingredients like glycerin and allantoin keep skin comfortable. It is unlikely to cause irritation or breakouts, and any mild purging may happen as your skin adjusts to the renewal process.
Sources: [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for acne-prone skin

- [Clinique Fresh Pressed Daily Booster with Pure Vitamin C 10%](https://lovi.care/skincare/ae/p/clinique/fresh-pressed-daily-booster-with-pure-vitamin-c-10/for/acne-prone-skin) — Superior fit — AED 365.22 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/ae/p/skinceuticals/c-e-ferulic/for/acne-prone-skin) — Superior fit — AED 715.99 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/ae/p/neogen-dermalogy/real-vitamin-c-serum/for/acne-prone-skin) — Superior fit — AED 89.30 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/ae/p/cerave/foaming-facial-cleanser/for/acne-prone-skin) — Superior fit — AED 49.95 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/ae/p/some-by-mi/snail-truecica-miracle-repair-toner/for/acne-prone-skin) — Superior fit — AED 49.99 at Amazon
- Moisturizer: [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/ae/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/acne-prone-skin) — Superior fit — AED 91.81 at Amazon

## Where to buy

No store in United Arab Emirates has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Retinol, Bakuchiol, Astaxanthin, Sodium Hyaluronate, Punica Granatum Fruit Extract, Aspalathus Linearius Extract, Allantoin, Sodium Pca, Caprylic Capric Triglyceride, Carbomer, Leuconostoc Radish Root Ferment Filtrate, Potassium Hydroxide, Potassium Sorbate, Sodium Benzoate, Polysorbate 20, Phenoxyethanol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/derma-e/retinol-concentrated-serum/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/derma-e/retinol-concentrated-serum/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/derma-e/retinol-concentrated-serum/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/derma-e/retinol-concentrated-serum/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/derma-e/retinol-concentrated-serum/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/derma-e/retinol-concentrated-serum/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/derma-e/retinol-concentrated-serum/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/derma-e/retinol-concentrated-serum/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/derma-e/retinol-concentrated-serum/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/derma-e/retinol-concentrated-serum/for/acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/derma-e/retinol-concentrated-serum/for/acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/derma-e/retinol-concentrated-serum/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/derma-e/retinol-concentrated-serum/for/acne-prone-skin (this page)